Published in Mol Pharmacol on December 01, 1995
The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels. Br J Pharmacol (2013) 1.88
Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A). J Physiol (1998) 1.20
Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor. J Biol Chem (2008) 1.07
Therapeutics of 5-HT3 receptor antagonists: current uses and future directions. Pharmacol Ther (2011) 1.07
Using guinea pigs in studies relevant to asthma and COPD. Pulm Pharmacol Ther (2008) 0.98
Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E. J Comp Neurol (2011) 0.96
Serotonin 5-HT(3) receptors in rat CA1 hippocampal interneurons: functional and molecular characterization. J Physiol (2002) 0.95
The 4'lysine in the putative channel lining domain affects desensitization but not the single-channel conductance of recombinant homomeric 5-HT3A receptors. J Physiol (2000) 0.95
Engineering a prokaryotic Cys-loop receptor with a third functional domain. J Biol Chem (2011) 0.94
Characterization of a human 5-hydroxytryptamine3 receptor type A (h5-HT3R-AS) subunit stably expressed in HEK 293 cells. Br J Pharmacol (1996) 0.93
Identification of critical residues in loop E in the 5-HT3ASR binding site. BMC Biochem (2002) 0.91
Promiscuous coassembly of serotonin 5-HT3 and nicotinic alpha4 receptor subunits into Ca(2+)-permeable ion channels. Proc Natl Acad Sci U S A (1998) 0.90
RIC-3 exclusively enhances the surface expression of human homomeric 5-hydroxytryptamine type 3A (5-HT3A) receptors despite direct interactions with 5-HT3A, -C, -D, and -E subunits. J Biol Chem (2010) 0.86
Immunomodulatory effects mediated by serotonin. J Immunol Res (2015) 0.85
Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study. Transl Psychiatry (2012) 0.85
Identification of a domain which affects kinetics and antagonistic potency of clozapine at 5-HT3 receptors. PLoS One (2009) 0.80
Colchicine: a novel positive allosteric modulator of the human 5-hydroxytryptamine3A receptor. J Pharmacol Exp Ther (2009) 0.79
Interactions of metoclopramide and ergotamine with human 5-HT(3A) receptors and human 5-HT reuptake carriers. Br J Pharmacol (2005) 0.77
Deletion of the 5-HT(3A)-receptor subunit blunts the induction of cocaine sensitization. Genes Brain Behav (2007) 0.77
Guide to Receptors and Channels (GRAC), 3rd edition. Br J Pharmacol (2008) 13.18
The 5-HT3B subunit is a major determinant of serotonin-receptor function. Nature (1999) 2.91
The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid. Proc Natl Acad Sci U S A (1997) 2.73
Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments. Proc Natl Acad Sci U S A (1984) 2.51
Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor. Br J Pharmacol (1997) 2.08
Neurosteroids and GABAA receptor function. Trends Pharmacol Sci (1995) 1.87
The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones. Br J Pharmacol (1991) 1.81
SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology (1997) 1.76
Molecular cloning and complete amino-acid sequence of form-I phosphoinositide-specific phospholipase C. Nature (1988) 1.68
Guide to Receptors and Channels (GRAC), 2nd edition (2007 Revision). Br J Pharmacol (2007) 1.56
The properties of 5-HT3 receptors in clonal cell lines studied by patch-clamp techniques. Br J Pharmacol (1989) 1.54
Modulation of the GABAA receptor by progesterone metabolites. Proc R Soc Lond B Biol Sci (1987) 1.48
Closure of membrane channels gated by glutamate receptors may be a two-step process. Nature (1982) 1.45
Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase. Mol Cell Biol (1990) 1.45
Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS. Neuropharmacology (2000) 1.43
For the benefit of all. Hastings Cent Rep (1994) 1.41
Modulation of GABAA receptor activity by alphaxalone. Br J Pharmacol (1987) 1.40
Non-random openings and concentration-dependent lifetimes of glutamate-gated channels in muscle membrane. Nature (1981) 1.39
The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study. Br J Pharmacol (1997) 1.37
Modulation of the GABAA receptor by depressant barbiturates and pregnane steroids. Br J Pharmacol (1988) 1.35
Cloning and functional expression of an apparent splice variant of the murine 5-HT3 receptor A subunit. Eur J Pharmacol (1993) 1.34
Novel compounds selectively enhance delta subunit containing GABA A receptors and increase tonic currents in thalamus. Neuropharmacology (2008) 1.32
Further characterization of 5-hydroxytryptamine receptors (putative 5-HT2B) in rat stomach fundus longitudinal muscle. Br J Pharmacol (1994) 1.31
Antagonism of GABAA receptors by 4-quinolones. J Antimicrob Chemother (1993) 1.25
Divalent cations modulate 5-HT3 receptor-induced currents in N1E-115 neuroblastoma cells. Eur J Pharmacol (1988) 1.25
Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A). J Physiol (1998) 1.20
Recent advances in the electrophysiological characterization of 5-HT3 receptors. Trends Pharmacol Sci (1992) 1.19
Structure of the mouse glial fibrillary acidic protein gene: implications for the evolution of the intermediate filament multigene family. Nucleic Acids Res (1985) 1.19
Pharmacological comparison of human homomeric 5-HT3A receptors versus heteromeric 5-HT3A/3B receptors. Neuropharmacology (2001) 1.17
Complementary regulation of anaesthetic activation of human (alpha6beta3gamma2L) and Drosophila (RDL) GABA receptors by a single amino acid residue. J Physiol (1999) 1.16
Modulation of native and recombinant GABA(A) receptors by endogenous and synthetic neuroactive steroids. Brain Res Brain Res Rev (2001) 1.15
Steroid hormones and neurosteroids in normal and pathological aging of the nervous system. Prog Neurobiol (2003) 1.15
In vitro and in vivo profile of SB 206553, a potent 5-HT2C/5-HT2B receptor antagonist with anxiolytic-like properties. Br J Pharmacol (1996) 1.14
Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed in Xenopus laevis oocytes. Br J Pharmacol (1996) 1.14
Neuroactive steroids and inhibitory neurotransmission: mechanisms of action and physiological relevance. Neuroscience (2005) 1.14
Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor. J Pharmacol Exp Ther (1997) 1.11
The structure and (local) stability constants of borate esters of mono- and di-saccharides as studied by 11B and 13C NMR spectroscopy. Carbohydr Res (1994) 1.11
Drug-induced modification of ionic conductance at the neuromuscular junction. Annu Rev Pharmacol Toxicol (1983) 1.10
An electrophysiological investigation of the properties of a murine recombinant 5-HT3 receptor stably expressed in HEK 293 cells. Br J Pharmacol (1995) 1.09
In vivo properties of SB 200646A, a 5-HT2C/2B receptor antagonist. Br J Pharmacol (1994) 1.09
The interaction of general anaesthetics and neurosteroids with GABA(A) and glycine receptors. Neurochem Int (1999) 1.09
Erp61 is GRP58, a stress-inducible luminal endoplasmic reticulum protein, but is devoid of phosphatidylinositide-specific phospholipase C activity. Arch Biochem Biophys (1994) 1.08
National Cancer Institute program on nutrition and cancer. Cancer Res (1975) 1.08
The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells. J Neurosci (1990) 1.07
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor. Proc Natl Acad Sci U S A (1994) 1.04
BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats. Neuropharmacology (1997) 1.04
Evidence for expression of the 5-hydroxytryptamine-2B receptor protein in the rat central nervous system. Neuroscience (1997) 1.03
The mechanism of action and pharmacological specificity of the anticonvulsant NMDA antagonist MK-801: a voltage clamp study on neuronal cells in culture. Br J Pharmacol (1989) 1.03
Proportion of heritable paraganglioma cases and associated clinical characteristics. Laryngoscope (2001) 1.02
An electrophysiological investigation of the characteristics and function of GABAA receptors on bovine adrenomedullary chromaffin cells. Pflugers Arch (1989) 1.01
On the mechanisms of kappa-opioid-induced diuresis. Br J Pharmacol (1986) 1.01
The effects of quinolones and NSAIDs upon GABA-evoked currents recorded from rat dorsal root ganglion neurones. J Antimicrob Chemother (1991) 1.01
The interaction of trichloroethanol with murine recombinant 5-HT3 receptors. Br J Pharmacol (1995) 1.01
Antagonism of 5-HT3 receptor mediated currents in murine N1E-115 neuroblastoma cells by (+)-tubocurarine. Neurosci Lett (1990) 0.99
The effect of a transmembrane amino acid on etomidate sensitivity of an invertebrate GABA receptor. Br J Pharmacol (1998) 0.99
DNase I hypersensitive sites of globin genes of uninduced Friend erythroleukemia cells and changes during induction with dimethyl sulfoxide. J Biol Chem (1983) 0.99
Guide to receptors and channels, 1st edition. Br J Pharmacol (2004) 0.99
A comparison of the facilitatory actions of 4-aminopyridine methiodide and 4-aminopyridine on neuromuscular transmission. Br J Pharmacol (1979) 0.99
Neurosteroid modulation of native and recombinant GABAA receptors. Cell Mol Neurobiol (1996) 0.98
Effects of the 5-HT2B receptor agonist, BW 723C86, on three rat models of anxiety. Br J Pharmacol (1996) 0.98
The interaction of anaesthetic steroids with recombinant glycine and GABAA receptors. Br J Anaesth (2004) 0.97
Pharmacological characterisation of [35S]-GTPgammaS binding to Chinese hamster ovary cell membranes stably expressing cloned human 5-HT1D receptor subtypes. J Recept Signal Transduct Res (1997) 0.97
Guide to receptors and channels, 2nd edition. Br J Pharmacol (2006) 0.97
General anaesthetic action at transmitter-gated inhibitory amino acid receptors. Trends Pharmacol Sci (1999) 0.97
Steroid modulation of the GABAA receptor complex: electrophysiological studies. Ciba Found Symp (1990) 0.97
A patch clamp study of the nicotinic acetylcholine receptor of bovine adrenomedullary chromaffin cells in culture. J Physiol (1992) 0.96
Electrophysiology of 5-HT3 receptors in neuronal cell lines. Trends Pharmacol Sci (1989) 0.96
BRL 46470 potently antagonizes neural responses activated by 5-HT3 receptors. Neuropharmacology (1993) 0.96
Influence of sex-steroid hormones on the regulation of lymphocyte beta 2-adrenoceptors during the menstrual cycle. Br J Clin Pharmacol (1994) 0.95
The 4'lysine in the putative channel lining domain affects desensitization but not the single-channel conductance of recombinant homomeric 5-HT3A receptors. J Physiol (2000) 0.95
Cardiac valve replacement with the stabilized glutaraldehyde porcine aortic valve: indications, operative results, and followup. Chest (1975) 0.95
Activation of 5-HT2B receptors in the medial amygdala causes anxiolysis in the social interaction test in the rat. Neuropharmacology (1997) 0.94
A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A) receptors. Br J Pharmacol (2013) 0.94
Synthesis, characterization, and relaxivity of two linear Gd(DTPA)-polymer conjugates. Bioconjug Chem (2001) 0.94
Molecular determinants of (+)-tubocurarine binding at recombinant 5-hydroxytryptamine3A receptor subunits. Mol Pharmacol (1999) 0.94