Published in J Biol Chem on November 15, 1996
Rab11 regulates the compartmentalization of early endosomes required for efficient transport from early endosomes to the trans-golgi network. J Cell Biol (2000) 3.01
AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain. Biochem J (2005) 2.76
Phagosome maturation: going through the acid test. Nat Rev Mol Cell Biol (2008) 2.53
ER to Golgi transport: Requirement for p115 at a pre-Golgi VTC stage. J Cell Biol (1999) 1.57
Rab2 GTPase regulates vesicle trafficking between the endoplasmic reticulum and the Golgi bodies and is important to pollen tube growth. Plant Cell (2002) 1.57
p53/58 binds COPI and is required for selective transport through the early secretory pathway. J Cell Biol (1997) 1.33
Constructing a Golgi complex. J Cell Biol (2001) 1.32
Rab6 and Rab11 regulate Chlamydia trachomatis development and golgin-84-dependent Golgi fragmentation. PLoS Pathog (2009) 1.31
Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein. Mol Biol Cell (2002) 1.21
A Rab2 mutant with impaired GTPase activity stimulates vesicle formation from pre-Golgi intermediates. Mol Biol Cell (1999) 1.21
Regulation of anterograde transport of adrenergic and angiotensin II receptors by Rab2 and Rab6 GTPases. Cell Signal (2007) 1.21
UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. J Cell Biol (2009) 1.16
UNC-108/Rab2 regulates postendocytic trafficking in Caenorhabditis elegans. Mol Biol Cell (2008) 1.15
Endocytic Rab proteins are required for hepatitis C virus replication complex formation. Virology (2009) 1.14
Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2. J Cell Biol (2009) 1.11
Two Rab proteins, vesicle-associated membrane protein 2 (VAMP-2) and secretory carrier membrane proteins (SCAMPs), are present on immunoisolated parietal cell tubulovesicles. Biochem J (1997) 1.09
Are Rab proteins the link between Golgi organization and membrane trafficking? Cell Mol Life Sci (2012) 1.08
The Anaplasma phagocytophilum-occupied vacuole selectively recruits Rab-GTPases that are predominantly associated with recycling endosomes. Cell Microbiol (2010) 1.07
An overexpression screen of Toxoplasma gondii Rab-GTPases reveals distinct transport routes to the micronemes. PLoS Pathog (2013) 1.05
Discovery of novel genetic networks associated with 19 economically important traits in beef cattle. Int J Biol Sci (2009) 1.02
A GAPDH mutant defective in Src-dependent tyrosine phosphorylation impedes Rab2-mediated events. Traffic (2007) 0.99
New putative chloroplast vesicle transport components and cargo proteins revealed using a bioinformatics approach: an Arabidopsis model. PLoS One (2013) 0.97
Rab2 utilizes glyceraldehyde-3-phosphate dehydrogenase and protein kinase C{iota} to associate with microtubules and to recruit dynein. J Biol Chem (2008) 0.96
Distinct yet overlapping roles of Rab GTPases on synaptic vesicles. Small GTPases (2011) 0.93
Intracellular trafficking and synaptic function of APL-1 in Caenorhabditis elegans. PLoS One (2010) 0.89
Genetic analysis of posterior medial barrel subfield (PMBSF) size in somatosensory cortex (SI) in recombinant inbred strains of mice. BMC Neurosci (2008) 0.89
The Rab2A GTPase promotes breast cancer stem cells and tumorigenesis via Erk signaling activation. Cell Rep (2015) 0.88
The golgin GMAP-210 is required for efficient membrane trafficking in the early secretory pathway. J Cell Sci (2015) 0.83
Rab GTPases act in sequential steps to regulate phagolysosome formation. Small GTPases (2010) 0.82
Functional Characterization of Monomeric GTPase Rab1 in the Secretory Pathway of Leishmania. J Biol Chem (2015) 0.81
Expressed sequence tags (ESTs) analysis of Acanthamoeba healyi. Korean J Parasitol (2001) 0.81
Endoplasmic reticulum chaperones and oxidoreductases: critical regulators of tumor cell survival and immunorecognition. Front Oncol (2014) 0.80
AtRabD2b and AtRabD2c have overlapping functions in pollen development and pollen tube growth. BMC Plant Biol (2011) 0.79
Structural analysis of Brucella abortus RicA substitutions that do not impair interaction with human Rab2 GTPase. BMC Biochem (2012) 0.78
Proteomic analysis of the Ehrlichia chaffeensis phagosome in cultured DH82 cells. PLoS One (2014) 0.77
Molecular structure of the Brucella abortus metalloprotein RicA, a Rab2-binding virulence effector. Biochemistry (2013) 0.77
RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs. EMBO Rep (2016) 0.77
Structures of Drosophila melanogaster Rab2 and Rab3 bound to GMPPNP. Acta Crystallogr F Struct Biol Commun (2015) 0.76
GAPDH binds Akt to facilitate cargo transport in the early secretory pathway. Exp Cell Res (2016) 0.75
The impact of erdosteine on cisplatin-induced ototoxicity: a proteomics approach. Eur Arch Otorhinolaryngol (2016) 0.75
Methanogens: reevaluation of a unique biological group. Microbiol Rev (1979) 29.84
The phylogeny of prokaryotes. Science (1980) 24.57
New approach to the cultivation of methanogenic bacteria: 2-mercaptoethanesulfonic acid (HS-CoM)-dependent growth of Methanobacterium ruminantium in a pressureized atmosphere. Appl Environ Microbiol (1976) 15.95
Reconstitution of the transport of protein between successive compartments of the Golgi measured by the coupled incorporation of N-acetylglucosamine. Cell (1984) 10.74
Classification of methanogenic bacteria by 16S ribosomal RNA characterization. Proc Natl Acad Sci U S A (1977) 5.09
Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science (2000) 4.56
Semi-intact cells permeable to macromolecules: use in reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex. Cell (1987) 4.39
GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex. J Cell Biol (1992) 4.34
Role for adenosine triphosphate in regulating the assembly and transport of vesicular stomatitis virus G protein trimers. J Cell Biol (1987) 3.84
Dominant inhibitory mutants of ARF1 block endoplasmic reticulum to Golgi transport and trigger disassembly of the Golgi apparatus. J Biol Chem (1994) 3.71
Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein. Nature (1989) 3.62
Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum to Golgi transport. J Cell Biol (1995) 3.57
Characterization of protein transport between successive compartments of the Golgi apparatus: asymmetric properties of donor and acceptor activities in a cell-free system. Arch Biochem Biophys (1985) 3.43
The organization of endoplasmic reticulum export complexes. J Cell Biol (1996) 3.32
Mutations in GDI1 are responsible for X-linked non-specific mental retardation. Nat Genet (1998) 3.30
Calcium and GTP: essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus. J Cell Biol (1989) 3.26
Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. J Cell Biol (1991) 3.22
Sequential intermediates in the pathway of intercompartmental transport in a cell-free system. Cell (1984) 3.07
A di-acidic signal required for selective export from the endoplasmic reticulum. Science (1997) 3.05
Specificity and biological distribution of coenzyme M (2-mercaptoethanesulfonic acid). J Bacteriol (1979) 2.95
Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments. J Cell Biol (1994) 2.75
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J Cell Biol (1995) 2.74
Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis--Golgi tethering. Traffic (2001) 2.53
ATP-coupled transport of vesicular stomatitis virus G protein between the endoplasmic reticulum and the Golgi. J Biol Chem (1986) 2.45
An ancient divergence among the bacteria. J Mol Evol (1977) 2.44
Morphological analysis of protein transport from the ER to Golgi membranes in digitonin-permeabilized cells: role of the P58 containing compartment. J Cell Biol (1992) 2.44
GTPases: multifunctional molecular switches regulating vesicular traffic. Annu Rev Biochem (1994) 2.44
Cargo selection by the COPII budding machinery during export from the ER. J Cell Biol (1998) 2.44
The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. J Cell Biol (2001) 2.41
Integration of endoplasmic reticulum signaling in health and disease. Nat Med (1999) 2.35
Transport of coenzyme M (2-mercaptoethanesulfonic acid) in Methanobacterium ruminantium. J Bacteriol (1979) 2.28
Quality control in the endoplasmic reticulum: folding and misfolding of vesicular stomatitis virus G protein in cells and in vitro. J Cell Biol (1990) 2.22
A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments. J Cell Biol (1994) 2.21
COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI. J Cell Biol (1996) 2.11
Isoprenoid modification of rab proteins terminating in CC or CXC motifs. Proc Natl Acad Sci U S A (1991) 1.99
Membrane dynamics at the endoplasmic reticulum-Golgi interface. J Cell Biol (1997) 1.96
A Rab1 mutant affecting guanine nucleotide exchange promotes disassembly of the Golgi apparatus. J Cell Biol (1994) 1.91
ATP-coupled transport of vesicular stomatitis virus G protein. Functional boundaries of secretory compartments. J Biol Chem (1986) 1.89
Beta-COP is essential for transport of protein from the endoplasmic reticulum to the Golgi in vitro. J Cell Biol (1993) 1.88
Rab1 and Ca2+ are required for the fusion of carrier vesicles mediating endoplasmic reticulum to Golgi transport. J Cell Biol (1994) 1.83
Synthetic peptides of the Rab effector domain inhibit vesicular transport through the secretory pathway. EMBO J (1990) 1.71
A novel prefusion complex formed during protein transport between Golgi cisternae in a cell-free system. J Biol Chem (1986) 1.68
Coenzyme M: preparation and assay. Methods Enzymol (1980) 1.66
Syntaxin 5 regulates endoplasmic reticulum to Golgi transport. J Biol Chem (1994) 1.63
Differential inhibition of multiple vesicular transport steps between the endoplasmic reticulum and trans Golgi network. J Biol Chem (1993) 1.63
Kinase signaling initiates coat complex II (COPII) recruitment and export from the mammalian endoplasmic reticulum. J Biol Chem (2000) 1.59
Structure and mutational analysis of Rab GDP-dissociation inhibitor. Nature (1996) 1.56
A di-acidic (DXE) code directs concentration of cargo during export from the endoplasmic reticulum. J Biol Chem (1999) 1.56
Multiple GTP-binding proteins regulate vesicular transport from the ER to Golgi membranes. J Cell Biol (1992) 1.52
Furin initiates gelsolin familial amyloidosis in the Golgi through a defect in Ca(2+) stabilization. EMBO J (2001) 1.52
Sequential transport of protein between the endoplasmic reticulum and successive Golgi compartments in semi-intact cells. J Biol Chem (1991) 1.52
Role of vesicle-associated syntaxin 5 in the assembly of pre-Golgi intermediates. Science (1998) 1.50
Evidence for the regulation of exocytic transport by protein phosphorylation. J Cell Biol (1992) 1.48
Crystal structure of Sar1-GDP at 1.7 A resolution and the role of the NH2 terminus in ER export. J Cell Biol (2001) 1.47
Cargo can modulate COPII vesicle formation from the endoplasmic reticulum. J Biol Chem (1999) 1.47
Reconstitution of transport of vesicular stomatitis virus G protein from the endoplasmic reticulum to the Golgi complex using a cell-free system. J Cell Biol (1987) 1.47
Getting into the Golgi. Trends Cell Biol (1998) 1.44
AP-2-containing clathrin coats assemble on mature lysosomes. J Cell Biol (1996) 1.43
Exocytotic fusion is activated by Rab3a peptides. Nature (1992) 1.41
Guanine nucleotide dissociation inhibitor is essential for Rab1 function in budding from the endoplasmic reticulum and transport through the Golgi stack. J Cell Biol (1994) 1.37
The mammalian guanine nucleotide exchange factor mSec12 is essential for activation of the Sar1 GTPase directing endoplasmic reticulum export. Traffic (2001) 1.35
Principles of selective transport: coat complexes hold the key. Trends Cell Biol (1996) 1.34
p53/58 binds COPI and is required for selective transport through the early secretory pathway. J Cell Biol (1997) 1.33
Ricin cytotoxicity is sensitive to recycling between the endoplasmic reticulum and the Golgi complex. J Biol Chem (1995) 1.30
A synthetic peptide of the rab3a effector domain stimulates amylase release from permeabilized pancreatic acini. Proc Natl Acad Sci U S A (1992) 1.29
The glycoprotein that is transported between successive compartments of the Golgi in a cell-free system resides in stacks of cisternae. Cell (1984) 1.29
Structural insights into the function of the Rab GDI superfamily. Trends Biochem Sci (1996) 1.28
Phytanyl-glycerol ethers and squalenes in the archaebacterium Methanobacterium thermoautotrophicum. J Mol Evol (1978) 1.28
Sequence homologies in the N-terminal region of the ribosomal 'A' proteins from Methanobacterium Thermoautotrophicum and Halobacterium cutirubrum. Biochim Biophys Acta (1980) 1.26
Organization of the Rab-GDI/CHM superfamily: the functional basis for choroideremia disease. Traffic (2001) 1.25
Protein sorting by directed maturation of Golgi compartments. Science (1999) 1.23
Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum to Golgi transport. J Biol Chem (1996) 1.22
Sequential intermediates in the transport of protein between the endoplasmic reticulum and the Golgi. J Biol Chem (1990) 1.21
Differential regulation of exocytosis by calcium and CAPS in semi-intact synaptosomes. Neuron (1998) 1.20
Mss4 does not function as an exchange factor for Rab in endoplasmic reticulum to Golgi transport. Mol Biol Cell (1997) 1.13
Expression and purification of mammalian Sarl. Methods Enzymol (1995) 1.12
Stimulation of insulin release from permeabilized HIT-T15 cells by a synthetic peptide corresponding to the effector domain of the small GTP-binding protein rab3. FEBS Lett (1993) 1.08
Synthetic peptides of the effector-binding domain of rab enhance secretion from digitonin-permeabilized chromaffin cells. FEBS Lett (1992) 1.04
Traffic pattern of cystic fibrosis transmembrane regulator through the early exocytic pathway. Traffic (2000) 1.02
Molecular basis for Rab prenylation. J Cell Biol (2000) 1.00
A Rab GTPase is required for homotypic assembly of the endoplasmic reticulum. J Biol Chem (1997) 0.97
Molecular dissection of guanine nucleotide dissociation inhibitor function in vivo. Rab-independent binding to membranes and role of Rab recycling factors. J Biol Chem (1999) 0.96
Selective transport of cargo between the endoplasmic reticulum and Golgi compartments. Histochem Cell Biol (1998) 0.94
Export of protein from the endoplasmic reticulum is regulated by a diacylglycerol/phorbol ester binding protein. J Biol Chem (1994) 0.93
Membrane fusion: timing is everything. Nature (1996) 0.92
A new functional domain of guanine nucleotide dissociation inhibitor (alpha-GDI) involved in Rab recycling. Traffic (2000) 0.90
Transport-coupled oligosaccharide processing in a cell-free system. Methods Enzymol (1983) 0.90
Expression of wild-type and mutant green fluorescent protein-Rab1 for fluorescence microscopy analysis. Methods Enzymol (2001) 0.88
Molecular role for the Rab binding platform of guanine nucleotide dissociation inhibitor in endoplasmic reticulum to Golgi transport. J Biol Chem (1998) 0.85
Proteostasis, an emerging therapeutic paradigm for managing inflammatory airway stress disease. Curr Mol Med (2012) 0.85
Stage-specific assays to study biosynthetic cargo selection and role of SNAREs in export from the endoplasmic reticulum and delivery to the Golgi. Methods (2000) 0.84
Purification of His6-tagged Rab1 proteins using bacterial and insect cell expression systems. Methods Enzymol (1995) 0.83
A new frontier in pharmacology: the endoplasmic reticulum as a regulated export pathway in health and disease. Expert Opin Ther Targets (2001) 0.83
Use of two-stage incubations to define sequential intermediates in endoplasmic reticulum to Golgi transport. Methods Enzymol (1992) 0.82
Transport of protein between endoplasmic reticulum and Golgi compartments in semiintact cells. Methods Enzymol (1992) 0.82
Transient expression of small GTPases to study protein transport along secretory pathway in vivo using recombinant T7 vaccinia virus system. Methods Enzymol (1995) 0.81
Purification of properties of dihydroorotase, a zinc-containing metalloenzyme in Clostridium oroticum. J Bacteriol (1976) 0.80
Structural basis for Rab function: an overview. Methods Enzymol (2001) 0.80
Membrane fusion. Bridging the gap by AAA ATPases. Nature (1997) 0.80
Purification and properties of rat liver Sec23-Sec24 complex. Methods Enzymol (2001) 0.79