Published in Biochemistry on September 20, 1977
Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursor. Proc Natl Acad Sci U S A (1986) 1.25
A fluorescence resonance energy transfer approach for monitoring protein-mediated glycolipid transfer between vesicle membranes. Anal Biochem (1999) 1.11
Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa. J Biol Chem (2010) 0.99
Binding of human blood-coagulation Factors IXa and X to phospholipid membranes. Biochem J (1984) 0.96
Effective electrostatic charge of coagulation factor X in solution and on phospholipid membranes: implications for activation mechanisms and structure-function relationships of the Gla domain. Biochem J (1998) 0.96
Studies on a family with combined functional deficiencies of vitamin K-dependent coagulation factors. J Clin Invest (1982) 0.90
Prothrombinase complex assembly on the platelet surface is mediated through the 74,000-dalton component of factor Va. Proc Natl Acad Sci U S A (1983) 0.90
Adsorption of bovine prothrombin to spread phospholipid monolayers. Biophys J (1997) 0.83
Structural basis for calcium and phosphatidylserine regulation of phospholipase C δ1. Biochemistry (2012) 0.82
Manipulation of the membrane binding site of vitamin K-dependent proteins: enhanced biological function of human factor VII. Proc Natl Acad Sci U S A (1998) 0.81
Caldesmon-phospholipid interaction. Effect of protein kinase C phosphorylation and sequence similarity with other phospholipid-binding proteins. Biochem J (1992) 0.78
Dissociation of peripheral protein-membrane complexes by high pressure. Protein Sci (1992) 0.78
Highly conserved residue arginine-15 is required for the Ca2+-dependent properties of the gamma-carboxyglutamic acid domain of human anticoagulation protein C and activated protein C. Biochem J (1997) 0.75
Aggregation of hapten-bearing liposomes mediated by specific antibodies. Biophys J (1993) 0.75
The mode of action of vitamin K. Identification of gamma-carboxyglutamic acid as a component of prothrombin. J Biol Chem (1974) 2.59
EUS-guided FNA immediately after unrevealing transbronchial needle aspiration in the evaluation of mediastinal lymphadenopathy: a prospective study. Gastrointest Endosc (2006) 2.15
Severe asthma. Singapore Med J (1997) 1.55
Asthma practice guidelines: common sense, expert opinion or evidence based approach? Singapore Med J (1996) 1.39
Metered-dose inhaler with spacer instead of nebulizer during the outbreak of severe acute respiratory syndrome in Singapore. Respir Care (2009) 1.38
The toxic strept syndrome: two case reports. Singapore Med J (1992) 1.38
Factors influencing morbidity and mortality in esophageal carcinoma. J Thorac Cardiovasc Surg (1978) 1.36
Interaction of vitamin K dependent proteins with membranes. Biochemistry (1978) 1.35
Klebsiella bacteraemia: a report of 101 cases from National University Hospital, Singapore. J Hosp Infect (1994) 1.30
Effects of volume history during spontaneous and acutely induced air-flow obstruction in asthma. Am Rev Respir Dis (1987) 1.29
Comparison of naturally occurring vitamin K-dependent proteins: correlation of amino acid sequences and membrane binding properties suggests a membrane contact site. Biochemistry (1997) 1.28
The mode of action of vitamin K. Isolation of a peptide containing the vitamin K-dependent portion of prothrombin. Proc Natl Acad Sci U S A (1973) 1.26
The purification and properties of an abnormal prothrombin protein produced by dicumarol-treated cows. A comparison to normal prothrombin. J Biol Chem (1972) 1.26
Tuberculosis associated with Mycobacterium tuberculosis Beijing and non-Beijing genotypes: a clinical and immunological comparison. BMC Infect Dis (2006) 1.25
Mode of action of vitamin K. Calcium binding properties of bovine prothrombin. Biochemistry (1972) 1.22
Gamma-carboxyglutamic acid: identification and distribution in vitamin K-dependent proteins. Mayo Clin Proc (1974) 1.22
Role of gamma-carboxyglutamic acid. An unusual protein transition required for the calcium-dependent binding of prothrombin to phospholipid. J Biol Chem (1976) 1.21
Role of substrate in imparting calcium and phospholipid requirements to protein kinase C activation. Biochemistry (1987) 1.19
Noninvasive ventilation in hypercapnic acute respiratory failure due to chronic obstructive pulmonary disease vs. other conditions: effectiveness and predictors of failure. Intensive Care Med (2005) 1.19
Utility of the electronic information resource UpToDate for clinical decision-making at bedside rounds. Singapore Med J (2012) 1.18
Mechanism of protein kinase C inhibition by sphingosine. Biochem Biophys Res Commun (1987) 1.11
Rapid shallow breathing (frequency-tidal volume ratio) did not predict extubation outcome. Chest (1994) 1.09
The collisional limit: an important consideration for membrane-associated enzymes and receptors. FASEB J (1988) 1.08
Role of gamma-carboxyglutamic acid. Cation specificity of prothrombin and factor X-phospholipid binding. J Biol Chem (1976) 1.07
Importance of phosphatidylethanolamine for association of protein kinase C and other cytoplasmic proteins with membranes. Biochemistry (1992) 1.06
Protein kinase C interaction with calcium: a phospholipid-dependent process. Biochemistry (1990) 1.06
Association of protein kinase C with phospholipid vesicles. Biochemistry (1987) 1.03
Failure of inhaled corticosteroids to modify bronchoconstrictor or bronchodilator responsiveness in middle-aged smokers with mild airflow obstruction. Chest (1992) 1.02
Severe community-acquired pneumonia in Singapore. Singapore Med J (1996) 1.01
Pentraxin family of proteins interact specifically with phosphorylcholine and/or phosphorylethanolamine. Biochemistry (1992) 0.99
Acute pancreatitis in Hong Kong. Br J Surg (1979) 0.99
Extensive segregation of acidic phospholipids in membranes induced by protein kinase C and related proteins. Biochemistry (1991) 0.99
Association of a protein with membrane vesicles at the collisional limit: studies with blood coagulation factor Va light chain also suggest major differences between small and large unilamellar vesicles. Biochemistry (1987) 0.99
Clinical study of hemospermia. Urology (1977) 0.99
Validation and clinical implications of the IDSA/ATS minor criteria for severe community-acquired pneumonia. Thorax (2009) 0.99
Isolation and characterization of vitamin K-dependent region of bovine blood clotting factor X. Proc Natl Acad Sci U S A (1975) 0.98
Interaction of prothrombin and blood-clotting factor X with membranes of varying composition. Biochemistry (1977) 0.98
The impact of a delay in intensive care unit admission for community-acquired pneumonia. Eur Respir J (2010) 0.96
Use of traditional versus electronic medical-information resources by residents and interns. Med Teach (2007) 0.96
Prothrombin association with phospholipid monolayers. Biochemistry (1983) 0.96
Role of substrate in determining the phospholipid specificity of protein kinase C activation. Biochemistry (1987) 0.96
[3H]diborane reduction of vitamin K-dependent calcium-binding proteins. Identification of a unique amino acid. J Biol Chem (1975) 0.95
The mechanism of action of uridine diphosphoglucose dehydrogenase. Uridine diphosphohexodialdoses as intermediates. J Biol Chem (1971) 0.95
Structure of the prothrombin- and blood clotting factor X-membrane complexes. Biochemistry (1977) 0.94
Membrane permeability to macromolecules mediated by the membrane attack complex. Biochemistry (1989) 0.94
Kinetic properties of enzyme populations in vivo: alkaline phosphatase of the Escherichia coli periplasm. Biochemistry (1992) 0.94
Independent association of serum amyloid P component, protein S, and complement C4b with complement C4b-binding protein and subsequent association of the complex with membranes. J Biol Chem (1990) 0.93
Constitutive activity of membrane-inserted protein kinase C. Biochem Biophys Res Commun (1988) 0.93
Differences in the effects of phorbol esters and diacylglycerols on protein kinase C. Biochemistry (1989) 0.92
Detection of Mycobacterium tuberculosis in sputum, pleural and bronchoalveolar lavage fluid using DNA amplification of the MPB 64 protein coding gene and IS6110 insertion element. Southeast Asian J Trop Med Public Health (1995) 0.92
Potent inhibition of terminal complement assembly by clusterin: characterization of its impact on C9 polymerization. Biochemistry (1997) 0.92
Controlled trial of intrapleural streptokinase in the treatment of pleural empyema and complicated parapneumonic effusions. Chest (1997) 0.92
Soluble triggering receptor expressed on myeloid cells-1 in acute respiratory infections. Eur Respir J (2006) 0.91
On the role of gamma-carboxyglutamic acid in calcium and phospholipid binding. Biochem Biophys Res Commun (1975) 0.90
Phosphorylation of lens intrinsic membrane proteins by protein kinase C. Eur J Biochem (1986) 0.90
Properties of membrane-inserted protein kinase C. Biochemistry (1988) 0.90
Electrochemical disinfection of drinking water using an activated-carbon-fiber reactor capable of monitoring its microbial fouling. Appl Microbiol Biotechnol (1997) 0.89
Reduced outer membrane permeability of Escherichia coli O157:H7: suggested role of modified outer membrane porins and theoretical function in resistance to antimicrobial agents. Biochemistry (2001) 0.89
Protein structural requirements and properties of membrane binding by gamma-carboxyglutamic acid-containing plasma proteins and peptides. J Biol Chem (1989) 0.89
Properties of a Ca2+ binding peptide from prothrombin. Biochem Biophys Res Commun (1974) 0.89
The carbohydrate of bovine prothrombin. Partial structural determination demonstrating the presence of -galactose residues. J Biol Chem (1972) 0.89
Amino-terminal alanine functions in a calcium-specific process essential for membrane binding by prothrombin fragment 1. Biochemistry (1988) 0.88
Regulation of the biosynthesis of cytochrome P-450 in brewer's yeast. Role of cyclic AMP. Biochim Biophys Acta (1978) 0.88
Binding and activation properties of human factor XII, prekallikrein, and derived peptides with acidic lipid vesicles. Biochemistry (1985) 0.88
Properties of the protein kinase C-phorbol ester interaction. Biochemistry (1989) 0.88
Kinetic and mechanistic analysis of prothrombin-membrane binding by stopped-flow light scattering. Biochemistry (1982) 0.88
Kinetic and hydrodynamic analysis of blood clotting factor V-membrane binding. Biochemistry (1982) 0.87
Bronchial hyperresponsiveness as a risk factor for progressive airflow obstruction in smokers. Bull Eur Physiopathol Respir (1988) 0.87
Empirical treatment of chronic cough--a cost-effectiveness analysis. Proc AMIA Symp (2001) 0.87
Substrate-specific stimulation of protein kinase C by polyvalent anion. Biochem Biophys Res Commun (1987) 0.86
Observations on the binding of lanthanides and calcium to vitamin D-dependent chick intestinal calcium-binding protein. Implications regarding calcium-binding protein function. J Biol Chem (1987) 0.86
Quasi-elastic laser light scattering. Methods Enzymol (1978) 0.85
Calcium and membrane-binding properties of monomeric and multimeric annexin II. Biochemistry (1994) 0.85
Cause, treatment and outcome of patients with life-threatening haemoptysis. Singapore Med J (1999) 0.85
Dynamic features of prothrombin interaction with phospholipid vesicles of different size and composition: implications for protein--membrane contact. Biochemistry (1996) 0.85
Moraxella catarrhalis respiratory infection in adults. Singapore Med J (1993) 0.85
Assembly of the membrane attack complex of complement on small unilamellar phospholipid vesicles. Biochemistry (1986) 0.85
Two-substrate reaction model for the heparin-catalyzed bovine antithrombin/protease reaction. J Biol Chem (1983) 0.85
Airway responsiveness of firefighters after smoke exposure. Br J Ind Med (1990) 0.85
Calcium and prothrombin-induced lateral phase separation in membranes. Biochemistry (1981) 0.84
Electron microscopy and hydrodynamic properties of blood clotting factor V and activation fragments of factor V with phospholipid vesicles. J Biol Chem (1984) 0.84
A simple, economical synthesis of uridine diphospho-N-acetylgalactosamine-6-3H. Anal Biochem (1971) 0.83
The physical significance of Km in the prothrombinase reaction. Biochem Biophys Res Commun (1983) 0.83
Uridine diphosphoglucose 4-epimerase: kinetic isotope effect. Biochim Biophys Acta (1970) 0.83
Highly sequential binding of protein kinase C and related proteins to membranes. Biochemistry (1991) 0.83
Tb3+ binding to bovine prothrombin and bovine prothrombin fragment 1. J Biol Chem (1985) 0.83
Origin of life: consideration of alternatives to proteins and nucleic acids. J Mol Evol (1980) 0.83
Transbronchial needle aspiration: initial experience in routine diagnostic bronchoscopy. Respir Med (2003) 0.83
Emergency department asthma: compliance with an evidence-based management algorithm. Ann Acad Med Singapore (2002) 0.83
Autophosphorylation of protein kinase C may require a high order of protein-phospholipid aggregates. J Biol Chem (1992) 0.82
Interaction of annexin VI with membranes: highly restricted dissipation of clustered phospholipids in membranes containing phosphatidylethanolamine. Biochemistry (1992) 0.82
Possible basis for the apparent surface selectivity of the contact activation of human blood coagulation factor XII. Biochemistry (1986) 0.82
Enhancing the activity of protein C by mutagenesis to improve the membrane-binding site: studies related to proline-10. Biochemistry (1997) 0.82
Audit of oxygen therapy in acute general medical wards following an educational programme. Ann Acad Med Singapore (2000) 0.82
Relationship of cytochrome P-450 to growth phase of brewer's yeast in 1 per cent- or 20 per cent-glucose medium. Biochem Soc Trans (1975) 0.81
Enhancement of human protein C function by site-directed mutagenesis of the gamma-carboxyglutamic acid domain. J Biol Chem (1998) 0.81
Manipulation of the membrane binding site of vitamin K-dependent proteins: enhanced biological function of human factor VII. Proc Natl Acad Sci U S A (1998) 0.81
The changing face of healthcare worker perceptions on powered air-purifying respirators during the SARS outbreak. Respirology (2005) 0.81