Published in Curr Opin Cell Biol on April 01, 1997
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Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior. Proc Natl Acad Sci U S A (2000) 2.60
Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. J Cell Biol (1998) 2.54
Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer. Breast Cancer Res (2000) 2.14
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Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1. Mol Biol Cell (1999) 2.02
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Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA. ChemMedChem (2007) 1.32
Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid. Proc Natl Acad Sci U S A (1999) 1.29
Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways. Proc Natl Acad Sci U S A (2002) 1.27
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Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: a mass spectrometric approach. Protein Sci (1999) 1.16
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Gelsolin and functionally similar actin-binding proteins are regulated by lysophosphatidic acid. EMBO J (1998) 1.09
RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao. Biochem J (2000) 1.07
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Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNS. Br J Pharmacol (2014) 1.00
Transcriptional and post-transcriptional mechanisms for lysophosphatidic acid-induced cyclooxygenase-2 expression in ovarian cancer cells. FASEB J (2008) 1.00
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Dual regulation of actin rearrangement through lysophosphatidic acid receptor in neuroblast cell lines: actin depolymerization by Ca(2+)-alpha-actinin and polymerization by rho. Mol Biol Cell (2002) 0.96
Novel advances in shotgun lipidomics for biology and medicine. Prog Lipid Res (2015) 0.95
NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid. J Cell Sci (2010) 0.94
Phospholipase A2beta mediates light-induced stomatal opening in Arabidopsis. J Exp Bot (2008) 0.94
Involvement of lipoxygenase in lysophosphatidic acid-stimulated hydrogen peroxide release in human HaCaT keratinocytes. Biochem J (2000) 0.93
Sphingosine 1-phosphate and its G protein-coupled receptors constitute a multifunctional immunoregulatory system. J Cell Biochem (2004) 0.92
Mechanisms of lysophosphatidic acid (LPA) mediated stimulation of intestinal apical Cl-/OH- exchange. Am J Physiol Gastrointest Liver Physiol (2009) 0.91
Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells. Exp Mol Med (2008) 0.90
Growth cone collapse through coincident loss of actin bundles and leading edge actin without actin depolymerization. J Cell Biol (2001) 0.89
P2Y5 is a G(alpha)i, G(alpha)12/13 G protein-coupled receptor activated by lysophosphatidic acid that reduces intestinal cell adhesion. Am J Physiol Gastrointest Liver Physiol (2009) 0.88
LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells. J Cell Physiol (2011) 0.88
Dynamic changes in neurexins' alternative splicing: role of Rho-associated protein kinases and relevance to memory formation. PLoS One (2011) 0.87
Mechanisms of the lysophosphatidic acid-induced increase in [Ca(2+)](i) in skeletal muscle cells. J Cell Mol Med (2008) 0.86
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Plasticity-related gene 3 promotes neurite shaft protrusion. BMC Neurosci (2013) 0.85
Gi-mediated tyrosine phosphorylation of Grb2 (growth-factor-receptor-bound protein 2)-bound dynamin-II by lysophosphatidic acid. Biochem J (1999) 0.83
Involvement of small GTPases Rho and Rac in the invasion of rat ascites hepatoma cells. Clin Exp Metastasis (1999) 0.83
Lysophospholipid receptors are differentially expressed in rat terminal Schwann cells, as revealed by a single cell rt-PCR and in situ hybridization. Acta Histochem Cytochem (2006) 0.82
Purification and characterization of a lysophosphatidic acid-specific phosphatase. Biochem J (1998) 0.82
Comprehensive and quantitative analysis of lysophospholipid molecular species present in obese mouse liver by shotgun lipidomics. Anal Chem (2015) 0.81
Lysophosphatidic acid induced nuclear translocation of nuclear factor-kappaB in Panc-1 cells by mobilizing cytosolic free calcium. World J Gastroenterol (2008) 0.81
Roles of atypical protein kinase C in lysophosphatidic acid-induced type II adenylyl cyclase activation in RAW 264.7 macrophages. Br J Pharmacol (1999) 0.79
Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity. J Biol Chem (2014) 0.79
Lysophosphatidic acid-mediated Ca2+ mobilization in human SH-SY5Y neuroblastoma cells is independent of phosphoinositide signalling, but dependent on sphingosine kinase activation. Biochem J (1999) 0.78
A lysophosphatidic acid analogue is revealed as a potent inhibitor of phosphatidylcholine synthesis, inducing apoptosis. Biochem J (2002) 0.77
Signaling pathway of lysophosphatidic Acid-induced contraction in feline esophageal smooth muscle cells. Korean J Physiol Pharmacol (2013) 0.77
Casein kinase iγ2 impairs fibroblasts actin stress fibers formation and delays cell cycle progression in g1. Int J Cell Biol (2012) 0.76
Progesterone produces antinociceptive and neuroprotective effects in rats with microinjected lysophosphatidic acid in the trigeminal nerve root. Mol Pain (2012) 0.76
Receptor-mediated vascular smooth muscle migration induced by LPA involves p38 mitogen-activated protein kinase pathway activation. Int J Mol Sci (2009) 0.75
Activation of lysophosphatidic Acid receptor is coupled to enhancement of ca(2+)-activated potassium channel currents. Korean J Physiol Pharmacol (2013) 0.75
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Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells. J Cell Biol (1998) 2.81
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Cell-cell adhesion mediated by a receptor-like protein tyrosine phosphatase. J Biol Chem (1993) 1.94
Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action. Cell Growth Differ (1993) 1.80
Rho family proteins in cell adhesion and cell migration. Eur J Cancer (2000) 1.68
Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1. Biochem J (1998) 1.67
Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology. J Cell Biol (1997) 1.64
Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade. J Biol Chem (2001) 1.43
Effects of tirapazamine on experimental colorectal liver metastases after radiofrequency ablation. Br J Surg (2012) 1.42
Characterization of p190RhoGEF, a RhoA-specific guanine nucleotide exchange factor that interacts with microtubules. J Biol Chem (2000) 1.41
Malignant effusions contain lysophosphatidic acid (LPA)-like activity. Ann Oncol (1998) 1.35
Cell surface expression of receptor protein tyrosine phosphatase RPTP mu is regulated by cell-cell contact. J Cell Biol (1995) 1.34
Interaction of c-Src with gap junction protein connexin-43. Role in the regulation of cell-cell communication. J Biol Chem (2000) 1.33
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Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis. Biochem J (1995) 1.26
Acute loss of cell-cell communication caused by G protein-coupled receptors: a critical role for c-Src. J Cell Biol (1998) 1.14
Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target. Mol Cell Proteomics (2011) 1.14
Increased cyclin A and decreased cyclin D levels in adenovirus 5 E1A-transformed rodent cell lines. Oncogene (1993) 1.11
Diacylglycerol kinase theta binds to and is negatively regulated by active RhoA. J Biol Chem (1999) 1.08
The value of miRNA in diagnosing thyroid cancer: a systematic review. Cancer Biomark (2012) 0.99
Purification and characterization of the cytoplasmic domain of human receptor-like protein tyrosine phosphatase RPTP mu. Biochemistry (1993) 0.97
Transient infection of freshly isolated human colorectal tumor cells by reovirus T3D intermediate subviral particles. Cancer Gene Ther (2008) 0.94
Immunosuppression promotes reovirus therapy of colorectal liver metastases. Cancer Gene Ther (2006) 0.90
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Early endostatin treatment inhibits metastatic seeding of murine colorectal cancer cells in the liver and their adhesion to endothelial cells. Br J Cancer (2005) 0.87
A strategy for genetic modification of the spike-encoding segment of human reovirus T3D for reovirus targeting. Gene Ther (2008) 0.86
Prolonged portal triad clamping during liver surgery for colorectal liver metastases is associated with decreased time to hepatic tumour recurrence. Eur J Surg Oncol (2009) 0.86
Intramolecular interactions between the juxtamembrane domain and phosphatase domains of receptor protein-tyrosine phosphatase RPTPmu. Regulation of catalytic activity. J Biol Chem (2000) 0.85
Recurrence location after resection of colorectal liver metastases influences prognosis. J Gastrointest Surg (2014) 0.81
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Differential regulation of the Wilms' tumor gene, WT1, during differentiation of embryonal carcinoma and embryonic stem cells. Cell Growth Differ (1997) 0.75