Published in J Cell Physiol on November 01, 2011
Nonmuscle myosin-2: mix and match. Cell Mol Life Sci (2012) 1.30
GPCRs and cancer. Acta Pharmacol Sin (2012) 1.02
Signaling through myosin light chain kinase in smooth muscles. J Biol Chem (2013) 0.98
Acylglycerol kinase promotes cell proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor. Mol Cancer (2014) 0.90
Direct observation of α-actinin tension and recruitment at focal adhesions during contact growth. Exp Cell Res (2014) 0.82
Curcumin inhibits LPA-induced invasion by attenuating RhoA/ROCK/MMPs pathway in MCF7 breast cancer cells. Clin Exp Med (2015) 0.80
The effect of including the C2 insert of nonmuscle myosin II-C on neuritogenesis. J Biol Chem (2013) 0.79
Life without double-headed non-muscle myosin II motor proteins. Front Chem (2014) 0.78
Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells. BMC Cancer (2014) 0.78
Promising pharmacological directions in the world of lysophosphatidic Acid signaling. Biomol Ther (Seoul) (2015) 0.78
Phosphorylation of Nonmuscle myosin II-A regulatory light chain resists Sendai virus fusion with host cells. Sci Rep (2015) 0.77
Migrastatics-Anti-metastatic and Anti-invasion Drugs: Promises and Challenges. Trends Cancer (2017) 0.77
Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis. Exp Mol Med (2017) 0.75
Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility. J Cell Biol (2017) 0.75
Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA (2003) 8.07
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science (1999) 7.12
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. Nat Med (2007) 5.06
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13. Science (1998) 4.62
Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk. Nat Cell Biol (2007) 4.26
Lysophospholipid receptors: signaling and biology. Annu Rev Biochem (2004) 3.78
Nonmuscle myosin II moves in new directions. J Cell Sci (2008) 3.39
Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases. Cancer Cell (2009) 3.36
Molecular mechanisms of nonmuscle myosin-II regulation. Curr Opin Cell Biol (1999) 3.05
Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. J Cell Biol (2004) 3.03
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem (2003) 2.98
Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells. J Cell Biol (1998) 2.64
Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid. J Biol Chem (1998) 2.49
Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid. J Biol Chem (1999) 2.44
Lysophosphatidic acid: G-protein signalling and cellular responses. Curr Opin Cell Biol (1997) 2.39
Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner. J Cell Biol (1999) 2.35
Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer. J Clin Invest (2004) 2.30
Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. J Biol Chem (2004) 2.17
Myosin phosphatase target subunit: Many roles in cell function. Biochem Biophys Res Commun (2007) 2.08
Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration. J Biol Chem (2006) 2.07
Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Mol Cell Biol (2002) 2.06
ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts. J Cell Biol (2002) 2.05
Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomes. Circ Res (1991) 1.98
Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration. Cancer Res (2006) 1.96
Lysophospholipid G protein-coupled receptors. J Biol Chem (2004) 1.88
Asymmetric distribution of myosin IIB in migrating endothelial cells is regulated by a rho-dependent kinase and contributes to tail retraction. Mol Biol Cell (2003) 1.85
Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts. Am J Physiol Cell Physiol (2001) 1.81
Mechanisms of lysophosphatidic acid production. Semin Cell Dev Biol (2004) 1.80
Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion. Genes Dev (2007) 1.77
Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis. J Biol Chem (2005) 1.77
Lysophosphatidic acid signalling. Curr Opin Cell Biol (1995) 1.66
Myosin-IIA heavy-chain phosphorylation regulates the motility of MDA-MB-231 carcinoma cells. Mol Biol Cell (2007) 1.64
The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases. Proc Natl Acad Sci U S A (2006) 1.61
Novel role for PDEF in epithelial cell migration and invasion. Cancer Res (2005) 1.57
Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK. J Cell Sci (2003) 1.51
Evidence for inserted sequences in the head region of nonmuscle myosin specific to the nervous system. Cloning of the cDNA encoding the myosin heavy chain-B isoform of vertebrate nonmuscle myosin. J Biol Chem (1992) 1.51
Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system. Mol Pharmacol (2000) 1.48
Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species. Structure-activity relationship of cloned LPA receptors. FEBS Lett (2000) 1.47
Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells. Mol Cancer Res (2009) 1.38
Molecular cloning and characterization of a lysophosphatidic acid receptor, Edg-7, expressed in prostate. Mol Pharmacol (2000) 1.37
Cloning of the cDNA encoding the myosin heavy chain of a vertebrate cellular myosin. Proc Natl Acad Sci U S A (1989) 1.34
Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion. Cancer Res (2008) 1.34
The G12/13-RhoA signaling pathway contributes to efficient lysophosphatidic acid-stimulated cell migration. Oncogene (2006) 1.33
Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma. Breast Cancer Res (2004) 1.29
LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells. Am J Physiol Cell Physiol (2007) 1.28
Role of lysophosphatidic acid and rho in glioma cell motility. Cell Motil Cytoskeleton (2000) 1.28
Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA(1), p42 and p38alpha. Biochim Biophys Acta (2007) 1.18
Applications of lentiviral vectors for shRNA delivery and transgenesis. Curr Gene Ther (2008) 1.14
A specific isoform of nonmuscle myosin II-C is required for cytokinesis in a tumor cell line. J Biol Chem (2006) 1.14
A novel myosin heavy chain gene in human chromosome 19q13.3. Gene (2003) 1.13
Lysophosphatidic acid synthesis and release. Prostaglandins Other Lipid Mediat (2001) 1.09
A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs). Cell Biochem Biophys (1999) 1.08
Lysophosphatidylserine stimulates chemotactic migration in U87 human glioma cells. Biochem Biophys Res Commun (2008) 0.95
Regulation of Rac and Cdc42 pathways by G(i) during lysophosphatidic acid-induced cell spreading. J Biol Chem (2000) 0.89
Leukomogenic factors downregulate heparanase expression in acute myeloid leukemia cells. Biochem Biophys Res Commun (2005) 0.78
Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol (2009) 7.77
Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk. Nat Cell Biol (2007) 4.26
Nonmuscle myosin II moves in new directions. J Cell Sci (2008) 3.39
Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice. J Biol Chem (2004) 3.31
Nonmuscle myosin IIb is involved in the guidance of fibroblast migration. Mol Biol Cell (2003) 3.02
Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem (2003) 2.98
Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens. Nat Cell Biol (2010) 2.51
Basic mechanism of three-dimensional collagen fibre transport by fibroblasts. Nat Cell Biol (2005) 2.28
Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors. J Biol Chem (2009) 2.16
Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C. J Biol Chem (2005) 1.86
Local cortical tension by myosin II guides 3D endothelial cell branching. Curr Biol (2009) 1.85
Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions. Nat Immunol (2010) 1.82
Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis. J Biol Chem (2005) 1.77
A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell (2004) 1.73
A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions. PLoS One (2007) 1.72
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. Blood (2007) 1.64
Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell (2007) 1.49
Replacement of nonmuscle myosin II-B with II-A rescues brain but not cardiac defects in mice. J Biol Chem (2007) 1.48
Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A. Blood (2011) 1.41
Ablation and mutation of nonmuscle myosin heavy chain II-B results in a defect in cardiac myocyte cytokinesis. Circ Res (2003) 1.40
Ablation of nonmuscle myosin II-B and II-C reveals a role for nonmuscle myosin II in cardiac myocyte karyokinesis. Mol Biol Cell (2010) 1.36
Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis. Proc Natl Acad Sci U S A (2012) 1.29
NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry. Curr Biol (2013) 1.29
Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics. J Cell Sci (2012) 1.26
Characterization of three full-length human nonmuscle myosin II paralogs. J Biol Chem (2013) 1.23
Fox-3 and PSF interact to activate neural cell-specific alternative splicing. Nucleic Acids Res (2010) 1.22
Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development (2009) 1.19
Nonmuscle myosin II isoform and domain specificity during early mouse development. Proc Natl Acad Sci U S A (2010) 1.16
Non-muscle myosin II regulates survival threshold of pluripotent stem cells. Nat Commun (2010) 1.16
Distinct and redundant roles of the non-muscle myosin II isoforms and functional domains. Biochem Soc Trans (2011) 1.15
A specific isoform of nonmuscle myosin II-C is required for cytokinesis in a tumor cell line. J Biol Chem (2006) 1.14
Non-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasion. Am J Pathol (2009) 1.09
A novel guanine nucleotide exchange factor MyoGEF is required for cytokinesis. Cell Cycle (2006) 1.07
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain. Oncogene (2003) 1.06
Induction of nonmuscle myosin heavy chain II-C by butyrate in RAW 264.7 mouse macrophages. J Biol Chem (2003) 1.05
Conditional ablation of nonmuscle myosin II-B delineates heart defects in adult mice. Circ Res (2009) 1.03
Function of the neuron-specific alternatively spliced isoforms of nonmuscle myosin II-B during mouse brain development. Mol Biol Cell (2006) 1.02
Pitx2a expression alters actin-myosin cytoskeleton and migration of HeLa cells through Rho GTPase signaling. Mol Biol Cell (2002) 1.01
An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation. J Biol Chem (2009) 0.97
Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress. Dev Cell (2012) 0.92
The B2 alternatively spliced isoform of nonmuscle myosin II-B lacks actin-activated MgATPase activity and in vitro motility. Biochem Biophys Res Commun (2007) 0.89
Nonmuscle myosin II is required for internalization of the epidermal growth factor receptor and modulation of downstream signaling. J Biol Chem (2012) 0.87
N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration. J Neurosci (2013) 0.84
Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A. Mol Biol Cell (2008) 0.83
Nonmuscle myosin II is a critical regulator of clathrin-mediated endocytosis. Traffic (2014) 0.81
In vivo studies on nonmuscle myosin II expression and function in heart development. Front Biosci (Landmark Ed) (2012) 0.81
Non-muscle myosin IIB is essential for cytokinesis during male meiotic cell divisions. Dev Biol (2012) 0.79
Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality. Dev Biol (2013) 0.77
Corrigendum: Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells. Nat Commun (2015) 0.75