Published in Proc Natl Acad Sci U S A on September 27, 2010
Lignin biosynthesis perturbations affect secondary cell wall composition and saccharification yield in Arabidopsis thaliana. Biotechnol Biofuels (2013) 1.33
A genomics approach to deciphering lignin biosynthesis in switchgrass. Plant Cell (2013) 1.26
MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula. Plant Cell (2011) 1.19
Salicylic acid mediates the reduced growth of lignin down-regulated plants. Proc Natl Acad Sci U S A (2011) 1.07
Characterization of a cinnamoyl-CoA reductase 1 (CCR1) mutant in maize: effects on lignification, fibre development, and global gene expression. J Exp Bot (2011) 1.03
Integrative analysis of transgenic alfalfa (Medicago sativa L.) suggests new metabolic control mechanisms for monolignol biosynthesis. PLoS Comput Biol (2011) 1.02
A polymer of caffeyl alcohol in plant seeds. Proc Natl Acad Sci U S A (2012) 0.99
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Structural studies of cinnamoyl-CoA reductase and cinnamyl-alcohol dehydrogenase, key enzymes of monolignol biosynthesis. Plant Cell (2014) 0.88
Functional analysis of metabolic channeling and regulation in lignin biosynthesis: a computational approach. PLoS Comput Biol (2012) 0.87
Medicago glucosyltransferase UGT72L1: potential roles in proanthocyanidin biosynthesis. Planta (2013) 0.87
Environmental stresses of field growth allow cinnamyl alcohol dehydrogenase-deficient Nicotiana attenuata plants to compensate for their structural deficiencies. Plant Physiol (2012) 0.84
Genetic architecture of plant stress resistance: multi-trait genome-wide association mapping. New Phytol (2016) 0.83
Reduced lignin content and altered lignin composition in the warm season forage grass Paspalum dilatatum by down-regulation of a Cinnamoyl CoA reductase gene. Transgenic Res (2014) 0.82
Proteomic analyses reveal differences in cold acclimation mechanisms in freezing-tolerant and freezing-sensitive cultivars of alfalfa. Front Plant Sci (2015) 0.78
Characterization of the cinnamoyl-CoA reductase (CCR) gene family in Populus tomentosa reveals the enzymatic active sites and evolution of CCR. Planta (2016) 0.77
Overexpression of artificially fused bifunctional enzyme 4CL1-CCR: a method for production of secreted 4-hydroxycinnamaldehydes in Escherichia coli. Microb Cell Fact (2015) 0.77
Transcriptome analysis of secondary cell wall development in Medicago truncatula. BMC Genomics (2016) 0.76
Transcriptome Analysis of a New Peanut Seed Coat Mutant for the Physiological Regulatory Mechanism Involved in Seed Coat Cracking and Pigmentation. Front Plant Sci (2016) 0.75
in Silico mutagenesis and docking studies of active site residues suggest altered substrate specificity and possible physiological role of Cinnamoyl CoA Reductase 1 (Ll-CCRH1). Bioinformation (2013) 0.75
Characterization of developmental- and stress-mediated expression of cinnamoyl-CoA reductase in kenaf (Hibiscus cannabinus L.). ScientificWorldJournal (2014) 0.75
Computational inference of the structure and regulation of the lignin pathway in Panicum virgatum. Biotechnol Biofuels (2015) 0.75
Structural and Biochemical Characterization of Cinnamoyl-CoA Reductases. Plant Physiol (2016) 0.75
Two distinct cinnamoyl-CoA reductases in Selaginella moellendorffii offer insight into the divergence of CCRs in plants. Planta (2017) 0.75
Wood chemistry analysis and expression profiling of a poplar clone expressing a tyrosine-rich peptide. Plant Cell Rep (2013) 0.75
SG2-type R2R3-MYB transcription factor MYB15 controls defense-induced lignification and basal immunity in Arabidopsis. Plant Cell (2017) 0.75
Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data. Neurosci Lett (2003) 18.34
A gene expression atlas of the model legume Medicago truncatula. Plant J (2008) 3.38
Cloning and characterization of irregular xylem4 (irx4): a severely lignin-deficient mutant of Arabidopsis. Plant J (2001) 2.93
Silencing of hydroxycinnamoyl-coenzyme A shikimate/quinate hydroxycinnamoyltransferase affects phenylpropanoid biosynthesis. Plant Cell (2004) 2.57
Improvement of biomass through lignin modification. Plant J (2008) 2.47
Lignin engineering. Curr Opin Plant Biol (2008) 2.40
Rewriting the lignin roadmap. Curr Opin Plant Biol (2002) 2.37
Large-scale insertional mutagenesis using the Tnt1 retrotransposon in the model legume Medicago truncatula. Plant J (2008) 2.37
CYP98A3 from Arabidopsis thaliana is a 3'-hydroxylase of phenolic esters, a missing link in the phenylpropanoid pathway. J Biol Chem (2001) 2.32
Flavonoid accumulation in Arabidopsis repressed in lignin synthesis affects auxin transport and plant growth. Plant Cell (2007) 2.27
Downregulation of caffeic acid 3-O-methyltransferase and caffeoyl CoA 3-O-methyltransferase in transgenic alfalfa. impacts on lignin structure and implications for the biosynthesis of G and S lignin. Plant Cell (2001) 2.23
Coniferyl aldehyde 5-hydroxylation and methylation direct syringyl lignin biosynthesis in angiosperms. Proc Natl Acad Sci U S A (1999) 2.17
Downregulation of cinnamoyl-coenzyme A reductase in poplar: multiple-level phenotyping reveals effects on cell wall polymer metabolism and structure. Plant Cell (2007) 1.71
Cinnamoyl CoA reductase, the first committed enzyme of the lignin branch biosynthetic pathway: cloning, expression and phylogenetic relationships. Plant J (1997) 1.64
Substrate preferences of O-methyltransferases in alfalfa suggest new pathways for 3-O-methylation of monolignols. Plant J (2001) 1.64
Antisense suppression of 4-coumarate:coenzyme A ligase activity in Arabidopsis leads to altered lignin subunit composition. Plant Cell (1997) 1.63
Multi-site genetic modulation of monolignol biosynthesis suggests new routes for formation of syringyl lignin and wall-bound ferulic acid in alfalfa (Medicago sativa L.). Plant J (2006) 1.54
Redirection of the phenylpropanoid pathway to feruloyl malate in Arabidopsis mutants deficient for cinnamoyl-CoA reductase 1. Planta (2007) 1.45
Essential role of caffeoyl coenzyme A O-methyltransferase in lignin biosynthesis in woody poplar plants. Plant Physiol (2000) 1.41
Using the acetyl bromide assay to determine lignin concentrations in herbaceous plants: some cautionary notes. J Agric Food Chem (1999) 1.40
Two cinnamoyl-CoA reductase (CCR) genes from Arabidopsis thaliana are differentially expressed during development and in response to infection with pathogenic bacteria. Phytochemistry (2001) 1.38
Convergent evolution of syringyl lignin biosynthesis via distinct pathways in the lycophyte Selaginella and flowering plants. Plant Cell (2010) 1.38
Multi-site genetic modification of monolignol biosynthesis in alfalfa (Medicago sativa): effects on lignin composition in specific cell types. New Phytol (2008) 1.31
The biosynthesis of monolignols: a "metabolic grid", or independent pathways to guaiacyl and syringyl units? Phytochemistry (2001) 1.28
Down-regulation of the AtCCR1 gene in Arabidopsis thaliana: effects on phenotype, lignins and cell wall degradability. Planta (2003) 1.26
Insertional mutagenesis: a Swiss Army knife for functional genomics of Medicago truncatula. Trends Plant Sci (2005) 1.23
Structural and compositional modifications in lignin of transgenic alfalfa down-regulated in caffeic acid 3-O-methyltransferase and caffeoyl coenzyme A 3-O-methyltransferase. Phytochemistry (2003) 1.22
Cell-specific and conditional expression of caffeoyl-coenzyme A-3-O-methyltransferase in poplar. Plant Physiol (2000) 1.10
Purification and Characterization of Cinnamoyl-Coenzyme A:NADP Oxidoreductase in Eucalyptus gunnii. Plant Physiol (1994) 1.09
Switchgrass (Panicum virgatum) possesses a divergent family of cinnamoyl CoA reductases with distinct biochemical properties. New Phytol (2009) 1.04
Epidermal patterning genes are active during embryogenesis in Arabidopsis. Development (2003) 1.03
Clarification of cinnamoyl co-enzyme A reductase catalysis in monolignol biosynthesis of Aspen. Plant Cell Physiol (2005) 0.98
Characterization of a cinnamoyl-CoA reductase that is associated with stem development in wheat. J Exp Bot (2007) 0.90
Reassessment of effects on lignification and vascular development in the irx4 Arabidopsis mutant. Phytochemistry (2005) 0.90
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
Sequencing of 50 human exomes reveals adaptation to high altitude. Science (2010) 11.27
Lignin modification improves fermentable sugar yields for biofuel production. Nat Biotechnol (2007) 5.91
The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature (2011) 4.94
Clinical analyses of clustered microcalcifications after autologous fat injection for breast augmentation. Plast Reconstr Surg (2011) 3.96
A second-generation combined linkage physical map of the human genome. Genome Res (2007) 3.60
Clinical application of massively parallel sequencing-based prenatal noninvasive fetal trisomy test for trisomies 21 and 18 in 11,105 pregnancies with mixed risk factors. Prenat Diagn (2012) 3.54
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A (2005) 3.37
Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis. Science (2003) 3.26
A putative lipid transfer protein involved in systemic resistance signalling in Arabidopsis. Nature (2002) 3.15
Influenza vaccine effectiveness in the 2011-2012 season: protection against each circulating virus and the effect of prior vaccination on estimates. Clin Infect Dis (2013) 3.00
Plant metabolomics: large-scale phytochemistry in the functional genomics era. Phytochemistry (2003) 2.84
Genetic manipulation of lignin reduces recalcitrance and improves ethanol production from switchgrass. Proc Natl Acad Sci U S A (2011) 2.77
Acceptance of and barriers to voluntary HIV counselling and testing among adults in Guizhou province, China. AIDS (2007) 2.35
Measurement of the quantum capacitance of graphene. Nat Nanotechnol (2009) 2.24
Metabolic profiling of Medicago truncatula cell cultures reveals the effects of biotic and abiotic elicitors on metabolism. J Exp Bot (2004) 2.04
Structural basis for the modulation of lignin monomer methylation by caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase. Plant Cell (2002) 1.87
Targeted down-regulation of cytochrome P450 enzymes for forage quality improvement in alfalfa (Medicago sativa L.). Proc Natl Acad Sci U S A (2005) 1.86
Effects of coumarate 3-hydroxylase down-regulation on lignin structure. J Biol Chem (2006) 1.83
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
Transcriptional networks for lignin biosynthesis: more complex than we thought? Trends Plant Sci (2011) 1.75
VIOLIN: vaccine investigation and online information network. Nucleic Acids Res (2007) 1.72
Virus infection improves drought tolerance. New Phytol (2008) 1.72
Genomics-based selection and functional characterization of triterpene glycosyltransferases from the model legume Medicago truncatula. Plant J (2005) 1.70
Crystal structures of a multifunctional triterpene/flavonoid glycosyltransferase from Medicago truncatula. Plant Cell (2005) 1.67
Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts. Cancer Res (2006) 1.66
The Vaccine Safety Datalink: a model for monitoring immunization safety. Pediatrics (2011) 1.60
An extracellular aspartic protease functions in Arabidopsis disease resistance signaling. EMBO J (2004) 1.58
A genomics approach to the early stages of triterpene saponin biosynthesis in Medicago truncatula. Plant J (2002) 1.57
MATE transporters facilitate vacuolar uptake of epicatechin 3'-O-glucoside for proanthocyanidin biosynthesis in Medicago truncatula and Arabidopsis. Plant Cell (2009) 1.57
Terpene biosynthesis in glandular trichomes of hop. Plant Physiol (2008) 1.57
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Pluripotency can be rapidly and efficiently induced in human amniotic fluid-derived cells. Hum Mol Genet (2009) 1.54
Multi-site genetic modulation of monolignol biosynthesis suggests new routes for formation of syringyl lignin and wall-bound ferulic acid in alfalfa (Medicago sativa L.). Plant J (2006) 1.54
Randomized phase II trial of lyophilized strawberries in patients with dysplastic precancerous lesions of the esophagus. Cancer Prev Res (Phila) (2011) 1.53
Early steps in proanthocyanidin biosynthesis in the model legume Medicago truncatula. Plant Physiol (2007) 1.52
Mutation of WRKY transcription factors initiates pith secondary wall formation and increases stem biomass in dicotyledonous plants. Proc Natl Acad Sci U S A (2010) 1.47
Different mechanisms for phytoalexin induction by pathogen and wound signals in Medicago truncatula. Proc Natl Acad Sci U S A (2007) 1.46
Delay discounting, locus of control, and cognitive impulsiveness independently predict tobacco dependence treatment outcomes in a highly dependent, lower socioeconomic group of smokers. Am J Addict (2012) 1.45
Noninvasive Fetal Trisomy (NIFTY) test: an advanced noninvasive prenatal diagnosis methodology for fetal autosomal and sex chromosomal aneuploidies. BMC Med Genomics (2012) 1.45
Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol (2014) 1.45
Translating and testing the ENABLE: CHF-PC concurrent palliative care model for older adults with heart failure and their family caregivers. J Palliat Med (2014) 1.41
The effect of complete percutaneous revascularisation with and without intravascular ultrasound guidance in the drugeluting stent era. EuroIntervention (2015) 1.40
Does obesity attenuate the effect of metabolic syndrome on chronic kidney disease in patients with coronary artery disease? Report from China heart survey. Circ J (2010) 1.40
Colocalization of L-phenylalanine ammonia-lyase and cinnamate 4-hydroxylase for metabolic channeling in phenylpropanoid biosynthesis. Plant Cell (2004) 1.40
Ten-year screening for thrombocytopenia after aortic valve replacement. Interact Cardiovasc Thorac Surg (2014) 1.39
Down-regulation of hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase in transgenic alfalfa affects lignification, development and forage quality. Phytochemistry (2007) 1.39
Impact of chronic kidney disease on patients with unprotected left main coronary artery disease treated with coronary artery bypass grafting or drug-eluting stents. Coron Artery Dis (2016) 1.39
Noninvasive prenatal diagnosis of common fetal chromosomal aneuploidies by maternal plasma DNA sequencing. J Matern Fetal Neonatal Med (2012) 1.38
Braided thin-walled biodegradable ureteral stent: preliminary evaluation in a canine model. Int J Urol (2013) 1.38
Local ionic and electron heating in single-molecule junctions. Nat Nanotechnol (2007) 1.35
Metabolomics reveals novel pathways and differential mechanistic and elicitor-specific responses in phenylpropanoid and isoflavonoid biosynthesis in Medicago truncatula cell cultures. Plant Physiol (2007) 1.34
Genome-wide analysis of phenylpropanoid defence pathways. Mol Plant Pathol (2010) 1.33
A transcript profiling approach reveals an epicatechin-specific glucosyltransferase expressed in the seed coat of Medicago truncatula. Proc Natl Acad Sci U S A (2008) 1.33
The mysteries of proanthocyanidin transport and polymerization. Plant Physiol (2010) 1.32
Gateway-compatible vectors for high-throughput gene functional analysis in switchgrass (Panicum virgatum L.) and other monocot species. Plant Biotechnol J (2011) 1.32
Multi-site genetic modification of monolignol biosynthesis in alfalfa (Medicago sativa): effects on lignin composition in specific cell types. New Phytol (2008) 1.31
A review on endogenous regenerative technology in periodontal regenerative medicine. Biomaterials (2010) 1.31
Phytochemistry meets genome analysis, and beyond. Phytochemistry (2003) 1.31
Functional characterization of the switchgrass (Panicum virgatum) R2R3-MYB transcription factor PvMYB4 for improvement of lignocellulosic feedstocks. New Phytol (2011) 1.31
Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis and pathogenic convergence with Salmonella typhi. PLoS One (2009) 1.30
The LAP1 MYB transcription factor orchestrates anthocyanidin biosynthesis and glycosylation in Medicago. Plant J (2009) 1.29
The 'ins' and 'outs' of flavonoid transport. Trends Plant Sci (2009) 1.29
On-off switches for secondary cell wall biosynthesis. Mol Plant (2011) 1.28
Silencing of 4-coumarate:coenzyme A ligase in switchgrass leads to reduced lignin content and improved fermentable sugar yields for biofuel production. New Phytol (2011) 1.28
Proanthocyanidin biosynthesis--still more questions than answers? Phytochemistry (2005) 1.26
Safety of trivalent inactivated influenza vaccine in children 6 to 23 months old. JAMA (2006) 1.26
A genomics approach to deciphering lignin biosynthesis in switchgrass. Plant Cell (2013) 1.26
Metabolic engineering of proanthocyanidins through co-expression of anthocyanidin reductase and the PAP1 MYB transcription factor. Plant J (2006) 1.25
Methyl jasmonate and yeast elicitor induce differential transcriptional and metabolic re-programming in cell suspension cultures of the model legume Medicago truncatula. Planta (2004) 1.25
Influenza vaccination and mortality benefits: new insights, new opportunities. Vaccine (2009) 1.24
Carbon dioxide flux from rice paddy soils in central China: effects of intermittent flooding and draining cycles. PLoS One (2013) 1.24
Crystal structure of Medicago truncatula UGT85H2--insights into the structural basis of a multifunctional (iso)flavonoid glycosyltransferase. J Mol Biol (2007) 1.24
Genome-wide association of body fat distribution in African ancestry populations suggests new loci. PLoS Genet (2013) 1.24
Secondary findings from non-invasive prenatal testing for common fetal aneuploidies by whole genome sequencing as a clinical service. Prenat Diagn (2013) 1.24
Structural and compositional modifications in lignin of transgenic alfalfa down-regulated in caffeic acid 3-O-methyltransferase and caffeoyl coenzyme A 3-O-methyltransferase. Phytochemistry (2003) 1.22
Transcriptome analysis of alfalfa glandular trichomes. Planta (2004) 1.22
A method for noninvasive detection of fetal large deletions/duplications by low coverage massively parallel sequencing. Prenat Diagn (2013) 1.22
Single- and cross-commodity discounting among cocaine addicts: the commodity and its temporal location determine discounting rate. Psychopharmacology (Berl) (2011) 1.22