Published in Proteins on May 01, 1997
Mutant alcohol dehydrogenase leads to improved ethanol tolerance in Clostridium thermocellum. Proc Natl Acad Sci U S A (2011) 1.96
The 1.9 A crystal structure of Escherichia coli MurG, a membrane-associated glycosyltransferase involved in peptidoglycan biosynthesis. Protein Sci (2000) 1.90
CtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fission. EMBO J (2003) 1.86
Identification of the C-signal, a contact-dependent morphogen coordinating multiple developmental responses in Myxococcus xanthus. Genes Dev (2003) 1.42
Separating NADH and NADPH fluorescence in live cells and tissues using FLIM. Nat Commun (2014) 1.37
Structure of the Escherichia coli malate synthase G:pyruvate:acetyl-coenzyme A abortive ternary complex at 1.95 A resolution. Protein Sci (2003) 1.30
Different biochemical mechanisms ensure network-wide balancing of reducing equivalents in microbial metabolism. J Bacteriol (2009) 1.30
A structurally conserved water molecule in Rossmann dinucleotide-binding domains. Protein Sci (2002) 1.17
V-shaped structure of glutamyl-tRNA reductase, the first enzyme of tRNA-dependent tetrapyrrole biosynthesis. EMBO J (2001) 1.16
Increased ethanol productivity in xylose-utilizing Saccharomyces cerevisiae via a randomly mutagenized xylose reductase. Appl Environ Microbiol (2010) 1.13
Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity. J Mol Biol (2006) 1.10
Engineering of coenzyme specificity of formate dehydrogenase from Saccharomyces cerevisiae. Biochem J (2002) 1.08
Structure of xylose reductase bound to NAD+ and the basis for single and dual co-substrate specificity in family 2 aldo-keto reductases. Biochem J (2003) 1.08
Computational design of Candida boidinii xylose reductase for altered cofactor specificity. Protein Sci (2009) 1.02
The crystal structure of shikimate dehydrogenase (AroE) reveals a unique NADPH binding mode. J Bacteriol (2003) 1.02
Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3. J Biol Chem (2009) 1.02
Crystal structure of cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase from a PCB degrader at 2.0 A resolution. Protein Sci (1998) 0.95
Investigating the coenzyme specificity of phenylacetone monooxygenase from Thermobifida fusca. Appl Microbiol Biotechnol (2010) 0.91
Regulation of photosynthetic GAPDH dissected by mutants. Plant Physiol (2005) 0.91
Structure and reaction mechanism of basil eugenol synthase. PLoS One (2007) 0.90
Structural studies of cinnamoyl-CoA reductase and cinnamyl-alcohol dehydrogenase, key enzymes of monolignol biosynthesis. Plant Cell (2014) 0.88
Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase. Proc Natl Acad Sci U S A (2002) 0.86
A core catalytic domain of the TyrA protein family: arogenate dehydrogenase from Synechocystis. Biochem J (2004) 0.84
Intracellular β-nicotinamide adenine dinucleotide inhibits the skeletal muscle ClC-1 chloride channel. J Biol Chem (2012) 0.84
Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.83
A Molecular Dynamics (MD) and Quantum Mechanics/Molecular Mechanics (QM/MM) study on Ornithine Cyclodeaminase (OCD): a tale of two iminiums. Int J Mol Sci (2012) 0.82
A soluble NADH-dependent fumarate reductase in the reductive tricarboxylic acid cycle of Hydrogenobacter thermophilus TK-6. J Bacteriol (2008) 0.81
Molecular characterization of an NADPH-dependent acetoin reductase/2,3-butanediol dehydrogenase from Clostridium beijerinckii NCIMB 8052. Appl Environ Microbiol (2014) 0.81
Structure of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase from Synechococcus PCC7942 complexed with NADP. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.80
Structure and function of glutamyl-tRNA reductase, the first enzyme of tetrapyrrole biosynthesis in plants and prokaryotes. Photosynth Res (2002) 0.79
Evolution of plant δ(1)-pyrroline-5-carboxylate reductases from phylogenetic and structural perspectives. Front Plant Sci (2015) 0.78
Functional divergence and convergent evolution in the plastid-targeted glyceraldehyde-3-phosphate dehydrogenases of diverse eukaryotic algae. PLoS One (2013) 0.78
Wanted: unique names for unique atom positions. PDB-wide analysis of diastereotopic atom names of small molecules containing diphosphate. BMC Bioinformatics (2008) 0.78
Molecular determinants of the cofactor specificity of ribitol dehydrogenase, a short-chain dehydrogenase/reductase. Appl Environ Microbiol (2012) 0.78
Nucleotide binding database NBDB - a collection of sequence motifs with specific protein-ligand interactions. Nucleic Acids Res (2015) 0.78
POR structural domains important for the enzyme activity in R. capsulatus complementation system. Photosynth Res (2002) 0.77
Crystal structure of human micro-crystallin complexed with NADPH. Protein Sci (2007) 0.76
Determinants of Cofactor Specificity for the Glucose-6-Phosphate Dehydrogenase from Escherichia coli: Simulation, Kinetics and Evolutionary Studies. PLoS One (2016) 0.76
Structure of RNA 3'-phosphate cyclase bound to substrate RNA. RNA (2014) 0.75
Two distinct cinnamoyl-CoA reductases in Selaginella moellendorffii offer insight into the divergence of CCRs in plants. Planta (2017) 0.75
Structural studies of shikimate dehydrogenase from Bacillus anthracis complexed with cofactor NADP. J Mol Model (2008) 0.75
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Knowledge-based protein secondary structure assignment. Proteins (1995) 14.08
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Weighting aligned protein or nucleic acid sequences to correct for unequal representation. J Mol Biol (1990) 11.50
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature (1986) 11.35
Primary structural comparison of RNA-dependent polymerases from plant, animal and bacterial viruses. Nucleic Acids Res (1984) 8.36
The integrase family of site-specific recombinases: regional similarities and global diversity. EMBO J (1986) 8.12
An attempt to unify the structure of polymerases. Protein Eng (1990) 7.93
Motif recognition and alignment for many sequences by comparison of dot-matrices. J Mol Biol (1991) 7.40
Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin. Cell (1991) 5.10
A conformational preference parameter to predict helices in integral membrane proteins. Biochim Biophys Acta (1986) 4.91
The primary structure of transcription factor TFIIIA has 12 consecutive repeats. FEBS Lett (1985) 4.73
The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors. EMBO J (1986) 4.47
Overseer: a nucleotide sequence searching tool. Comput Appl Biosci (1992) 4.46
Cloning of the human cDNA for the U1 RNA-associated 70K protein. EMBO J (1986) 4.43
Prediction of transmembrane segments in proteins utilising multiple sequence alignments. J Mol Biol (1994) 4.07
An assessment of amino acid exchange matrices in aligning protein sequences: the twilight zone revisited. J Mol Biol (1995) 3.74
The structure of bovine rhodopsin. Biophys Struct Mech (1983) 3.33
Similarity in gene organization and homology between proteins of animal picornaviruses and a plant comovirus suggest common ancestry of these virus families. Nucleic Acids Res (1984) 2.99
Suggestions for "safe" residue substitutions in site-directed mutagenesis. J Mol Biol (1991) 2.80
Thermal stability and protein structure. Biochemistry (1979) 2.73
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Protein thermal stability, hydrogen bonds, and ion pairs. J Mol Biol (1997) 2.69
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A possible nucleotide-binding domain in the tertiary fold of phosphoribosyltransferases. J Biol Chem (1983) 2.60
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Structural prediction of membrane-bound proteins. Eur J Biochem (1982) 2.44
Human adenosine deaminase. cDNA and complete primary amino acid sequence. J Biol Chem (1984) 2.33
The release of growth arrest by microinjection of adenovirus E1A DNA. EMBO J (1985) 2.32
Side-chain clusters in protein structures and their role in protein folding. J Mol Biol (1991) 2.24
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Ribosome-mediated translational pause and protein domain organization. Protein Sci (1996) 2.20
Evidence for a repeating domain in type I restriction enzymes. EMBO J (1985) 2.20
Seventy-five percent accuracy in protein secondary structure prediction. Proteins (1997) 2.16
A model for the tertiary structure of the 28 residue DNA-binding motif ('zinc finger') common to many eukaryotic transcriptional regulatory proteins. Protein Eng (1988) 1.98
Intramolecular cavities in globular proteins. Protein Eng (1994) 1.97
Rotamers: to be or not to be? An analysis of amino acid side-chain conformations in globular proteins. J Mol Biol (1993) 1.92
Protein-protein crystal-packing contacts. Protein Sci (1997) 1.89
Automated protein sequence database classification. I. Integration of compositional similarity search, local similarity search, and multiple sequence alignment. Bioinformatics (1998) 1.84
A sensitive procedure to compare amino acid sequences. J Mol Biol (1987) 1.84
Primary structural relationships may reflect similar DNA replication strategies. Virology (1986) 1.81
Sequence analysis and characterization of a maize gene encoding a high-sulfur zein protein of Mr 15,000. J Biol Chem (1986) 1.77
Engineering protein thermal stability. Sequence statistics point to residue substitutions in alpha-helices. J Mol Biol (1989) 1.74
A comparison of the heme binding pocket in globins and cytochrome b5. J Biol Chem (1975) 1.74
A structural model for maize zein proteins. J Biol Chem (1982) 1.73
Topology prediction of membrane proteins. Protein Sci (1996) 1.71
Transforming a set of biological flat file libraries to a fast access network. Comput Appl Biosci (1993) 1.69
Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase. Nucleic Acids Res (1991) 1.68
Determination of reliable regions in protein sequence alignments. Protein Eng (1990) 1.66
Sugar permeases of the bacterial phosphoenolpyruvate-dependent phosphotransferase system: sequence comparisons. FASEB J (1988) 1.64
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Automated protein sequence database classification. II. Delineation Of domain boundaries from sequence similarities. Bioinformatics (1998) 1.61
The primary structure of human secretogranin II, a widespread tyrosine-sulfated secretory granule protein that exhibits low pH- and calcium-induced aggregation. J Biol Chem (1989) 1.60
Fingers and helices. Nature (1987) 1.59
Three-dimensional Fourier synthesis of calf liver cytochrome b 5 at 2-8 A resolution. J Mol Biol (1972) 1.58
OBSTRUCT: a program to obtain largest cliques from a protein sequence set according to structural resolution and sequence similarity. Comput Appl Biosci (1992) 1.57
Prediction of membrane protein topology utilizing multiple sequence alignments. J Protein Chem (1997) 1.56
Structural similarity between legumin and vicilin storage proteins from legumes. EMBO J (1985) 1.49
The structure of cytochrome b 5 at 2.0 Angstrom resolution. Cold Spring Harb Symp Quant Biol (1972) 1.49
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Protein secondary structural types are differentially coded on messenger RNA. Protein Sci (1996) 1.47
A method to recognize distant repeats in protein sequences. Proteins (1993) 1.47
Identification of a trpG-related glutamine amide transfer domain in Escherichia coli GMP synthetase. J Biol Chem (1985) 1.44
Similarities in active center geometries of zinc-containing enzymes, proteases and dehydrogenases. J Mol Biol (1978) 1.40
DOMO: a new database of aligned protein domains. Trends Biochem Sci (1998) 1.38
Automated protein sequence pattern handling and PROSITE searching. Comput Appl Biosci (1991) 1.37
Principles of helix-helix packing in proteins: the helical lattice superposition model. J Mol Biol (1996) 1.37
Protein thermal stability: hydrogen bonds or internal packing? Fold Des (1997) 1.36
Protein secondary structure. Studies on the limits of prediction accuracy. Int J Pept Protein Res (1982) 1.35
Cavities and packing at protein interfaces. Protein Sci (1994) 1.34
Comparison of atomic solvation parametric sets: applicability and limitations in protein folding and binding. Protein Sci (1995) 1.33
TMAP: a new email and WWW service for membrane-protein structural predictions. Trends Biochem Sci (1995) 1.32
Hydrophobic patches on protein subunit interfaces: characteristics and prediction. Proteins (1997) 1.31
Sensitivity comparison of protein amino acid sequences. Methods Enzymol (1990) 1.28
Folding the main chain of small proteins with the genetic algorithm. J Mol Biol (1994) 1.28
An assessment of protein secondary structure prediction methods based on amino acid sequence. Biochim Biophys Acta (1976) 1.28
Scrutineer: a computer program that flexibly seeks and describes motifs and profiles in protein sequence databases. Comput Appl Biosci (1990) 1.25
Anatomy and evolution of proteins displaying the viral capsid jellyroll topology. J Mol Biol (1992) 1.25
Potential of genetic algorithms in protein folding and protein engineering simulations. Protein Eng (1992) 1.22
Prediction of secondary structural content of proteins from their amino acid composition alone. II. The paradox with secondary structural class. Proteins (1996) 1.22
A method to configure protein side-chains from the main-chain trace in homology modelling. J Mol Biol (1993) 1.22
Structural stability of halophilic proteins. Biochemistry (1981) 1.21
Is Sindbis a simple picornavirus with an envelope? EMBO J (1987) 1.21
The Chou-Fasman secondary structure prediction method with an extended data base. FEBS Lett (1978) 1.18
Accessibility to internal cavities and ligand binding sites monitored by protein crystallographic thermal factors. Proteins (1998) 1.16
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Structural prediction of sugar-binding proteins functional in chemotaxis and transport. J Biol Chem (1981) 1.14
Protein structure prediction: recognition of primary, secondary, and tertiary structural features from amino acid sequence. Crit Rev Biochem Mol Biol (1995) 1.14
Optimal protocol and trajectory visualization for conformational searches of peptides and proteins. J Mol Biol (1992) 1.12
The taxonomy of binding sites in proteins. Mol Cell Biochem (1978) 1.12
The role of side-chain hydrogen bonds in the formation and stabilization of secondary structure in soluble proteins. J Mol Biol (1994) 1.09
The structure of calf liver cytochrome b 5 at 2.8 A resolution. Nat New Biol (1971) 1.09
Structural adaptation of enzymes to low temperatures. Protein Eng (2001) 1.09
Correlation between side chain mobility and conformation in protein structures. Protein Eng (1997) 1.07
Prediction of secondary structural elements in glycerol-3-phosphate dehydrogenase by comparison with other dehydrogenases. Eur J Biochem (1980) 1.07
Quantification of secondary structure prediction improvement using multiple alignments. Protein Eng (1993) 1.05