Published in Proteins on May 01, 1997
Touring protein fold space with Dali/FSSP. Nucleic Acids Res (1998) 18.00
Towards understanding the first genome sequence of a crenarchaeon by genome annotation using clusters of orthologous groups of proteins (COGs). Genome Biol (2000) 6.50
Predicting protein function by genomic context: quantitative evaluation and qualitative inferences. Genome Res (2000) 5.14
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell Cycle (2009) 4.14
Structure-based activity prediction for an enzyme of unknown function. Nature (2007) 3.65
Expanding protein universe and its origin from the biological Big Bang. Proc Natl Acad Sci U S A (2002) 2.92
Phosphoesterase domains associated with DNA polymerases of diverse origins. Nucleic Acids Res (1998) 2.61
Emergence of protein fold families through rational design. PLoS Comput Biol (2006) 2.35
Melamine deaminase and atrazine chlorohydrolase: 98 percent identical but functionally different. J Bacteriol (2001) 1.61
Anaerobic catabolism of aromatic compounds: a genetic and genomic view. Microbiol Mol Biol Rev (2009) 1.59
AtzC is a new member of the amidohydrolase protein superfamily and is homologous to other atrazine-metabolizing enzymes. J Bacteriol (1998) 1.58
A gold standard set of mechanistically diverse enzyme superfamilies. Genome Biol (2006) 1.52
Functional annotation and three-dimensional structure of Dr0930 from Deinococcus radiodurans, a close relative of phosphotriesterase in the amidohydrolase superfamily. Biochemistry (2009) 1.47
PDBSiteScan: a program for searching for active, binding and posttranslational modification sites in the 3D structures of proteins. Nucleic Acids Res (2004) 1.41
Structural bases for CRMP function in plexin-dependent semaphorin3A signaling. EMBO J (2003) 1.29
SURFACE: a database of protein surface regions for functional annotation. Nucleic Acids Res (2004) 1.26
Purification, substrate range, and metal center of AtzC: the N-isopropylammelide aminohydrolase involved in bacterial atrazine metabolism. J Bacteriol (2002) 1.22
Single-cell genome and metatranscriptome sequencing reveal metabolic interactions of an alkane-degrading methanogenic community. ISME J (2013) 1.19
Ni uptake and limitation in marine Synechococcus strains. Appl Environ Microbiol (2007) 1.18
Inference of functional properties from large-scale analysis of enzyme superfamilies. J Biol Chem (2011) 1.17
N-Acetyl-D-glucosamine-6-phosphate deacetylase: substrate activation via a single divalent metal ion. Biochemistry (2007) 1.14
Collapsin response mediator protein-1: a novel invasion-suppressor gene. Clin Exp Metastasis (2003) 1.12
Catalytic mechanism and three-dimensional structure of adenine deaminase. Biochemistry (2011) 1.11
Functional annotation by identification of local surface similarities: a novel tool for structural genomics. BMC Bioinformatics (2005) 1.11
Substrate specificity of atrazine chlorohydrolase and atrazine-catabolizing bacteria. Appl Environ Microbiol (2000) 1.11
Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus. Arch Biochem Biophys (2009) 1.10
Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteins. Mol Biosyst (2009) 1.10
Similar active sites in lysostaphins and D-Ala-D-Ala metallopeptidases. Protein Sci (2004) 1.09
Uronate isomerase: a nonhydrolytic member of the amidohydrolase superfamily with an ambivalent requirement for a divalent metal ion. Biochemistry (2006) 1.07
Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily. J Biol Chem (2010) 1.07
Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri. Proc Natl Acad Sci U S A (2006) 1.07
Functional expression and characterization of the two cyclic amidohydrolase enzymes, allantoinase and a novel phenylhydantoinase, from Escherichia coli. J Bacteriol (2000) 1.04
TrzN from Arthrobacter aurescens TC1 Is a zinc amidohydrolase. J Bacteriol (2006) 1.03
Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies. J Struct Funct Genomics (2009) 1.00
Functional identification of incorrectly annotated prolidases from the amidohydrolase superfamily of enzymes. Biochemistry (2009) 0.99
Predicting ligand-binding function in families of bacterial receptors. Proc Natl Acad Sci U S A (2000) 0.99
CARF and WYL domains: ligand-binding regulators of prokaryotic defense systems. Front Genet (2014) 0.98
Evolutionarily conserved substrate substructures for automated annotation of enzyme superfamilies. PLoS Comput Biol (2008) 0.98
Substrate specificity and colorimetric assay for recombinant TrzN derived from Arthrobacter aurescens TC1. Appl Environ Microbiol (2005) 0.98
Structure and catalytic mechanism of LigI: insight into the amidohydrolase enzymes of cog3618 and lignin degradation. Biochemistry (2012) 0.97
Discovery and structure determination of the orphan enzyme isoxanthopterin deaminase . Biochemistry (2010) 0.94
Metal ion dependence of recombinant Escherichia coli allantoinase. J Bacteriol (2003) 0.94
Functional annotation of two new carboxypeptidases from the amidohydrolase superfamily of enzymes. Biochemistry (2009) 0.93
Amine-synthesizing enzyme N-substituted formamide deformylase: screening, purification, characterization, and gene cloning. Proc Natl Acad Sci U S A (2004) 0.92
A homology identification method that combines protein sequence and structure information. Protein Sci (1998) 0.92
Crystal structure of D-Hydantoinase from Burkholderia pickettii at a resolution of 2.7 Angstroms: insights into the molecular basis of enzyme thermostability. J Bacteriol (2003) 0.92
HorA web server to infer homology between proteins using sequence and structural similarity. Nucleic Acids Res (2009) 0.92
Three-dimensional structure and catalytic mechanism of cytosine deaminase. Biochemistry (2011) 0.91
Genes acquired by horizontal transfer are potentially involved in the evolution of phytopathogenicity in Moniliophthora perniciosa and Moniliophthora roreri, two of the major pathogens of cacao. J Mol Evol (2009) 0.91
Hydroxyatrazine N-ethylaminohydrolase (AtzB): an amidohydrolase superfamily enzyme catalyzing deamination and dechlorination. J Bacteriol (2007) 0.91
Assignment of pterin deaminase activity to an enzyme of unknown function guided by homology modeling and docking. J Am Chem Soc (2013) 0.90
Dihydropyrimidine amidohydrolases and dihydroorotases share the same origin and several enzymatic properties. Nucleic Acids Res (2003) 0.89
The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily. Biochemistry (2009) 0.89
Dali server update. Nucleic Acids Res (2016) 0.88
Functional annotation and three-dimensional structure of an incorrectly annotated dihydroorotase from cog3964 in the amidohydrolase superfamily. Biochemistry (2012) 0.88
Fold recognition without folds. Protein Sci (2002) 0.88
Structure-based function discovery of an enzyme for the hydrolysis of phosphorylated sugar lactones. Biochemistry (2012) 0.88
Widespread distribution of cell defense against D-aminoacyl-tRNAs. J Biol Chem (2009) 0.87
Catalytic improvement and evolution of atrazine chlorohydrolase. Appl Environ Microbiol (2009) 0.87
Functional characterization of allantoinase genes from Arabidopsis and a nonureide-type legume black locust. Plant Physiol (2004) 0.86
Structural and mechanistic characterization of L-histidinol phosphate phosphatase from the polymerase and histidinol phosphatase family of proteins. Biochemistry (2013) 0.86
Functional identification and structure determination of two novel prolidases from cog1228 in the amidohydrolase superfamily . Biochemistry (2010) 0.85
The pyrimidine nucleotide reductase step in riboflavin and F(420) biosynthesis in archaea proceeds by the eukaryotic route to riboflavin. J Bacteriol (2002) 0.84
Enzymatic degradation of chlorodiamino-s-triazine. Appl Environ Microbiol (2002) 0.84
Pa0148 from Pseudomonas aeruginosa catalyzes the deamination of adenine. Biochemistry (2011) 0.83
Enhancing the promiscuous phosphotriesterase activity of a thermostable lactonase (GkaP) for the efficient degradation of organophosphate pesticides. Appl Environ Microbiol (2012) 0.83
Discovery of a cAMP deaminase that quenches cyclic AMP-dependent regulation. ACS Chem Biol (2013) 0.83
A semiautomated approach to gene discovery through expressed sequence tag data mining: discovery of new human transporter genes. AAPS PharmSci (2003) 0.82
A common catalytic mechanism for proteins of the HutI family. Biochemistry (2008) 0.82
Phylogenetics in the bioinformatics culture of understanding. Comp Funct Genomics (2004) 0.82
Effect of metal binding and posttranslational lysine carboxylation on the activity of recombinant hydantoinase. J Biol Inorg Chem (2008) 0.82
Structure-guided discovery of new deaminase enzymes. J Am Chem Soc (2013) 0.80
A proton wire and water channel revealed in the crystal structure of isatin hydrolase. J Biol Chem (2014) 0.80
Evolution of cyclic amidohydrolases: a highly diversified superfamily. J Mol Evol (2013) 0.80
Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-fluoroorotate: catalytic activity is reflected by the crystal form. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.80
300-Fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization. Appl Environ Microbiol (2014) 0.80
The mononuclear metal center of type-I dihydroorotase from Aquifex aeolicus. BMC Biochem (2013) 0.79
Substrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase. J Am Chem Soc (2016) 0.79
Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron. Appl Environ Microbiol (2015) 0.78
Feature amplified voting algorithm for functional analysis of protein superfamily. BMC Genomics (2010) 0.78
Functional annotation and structural characterization of a novel lactonase hydrolyzing D-xylono-1,4-lactone-5-phosphate and L-arabino-1,4-lactone-5-phosphate. Biochemistry (2014) 0.78
Structures of bacterial kynurenine formamidase reveal a crowded binuclear zinc catalytic site primed to generate a potent nucleophile. Biochem J (2014) 0.78
Structural characterization and function determination of a nonspecific carboxylate esterase from the amidohydrolase superfamily with a promiscuous ability to hydrolyze methylphosphonate esters. Biochemistry (2014) 0.77
Beyond BLASTing: tertiary and quaternary structure analysis helps identify major vault proteins. Genome Biol Evol (2013) 0.77
Construction and evaluation of a novel bifunctional N-carbamylase-D-hydantoinase fusion enzyme. Appl Environ Microbiol (2000) 0.77
Prospecting for unannotated enzymes: discovery of a 3',5'-nucleotide bisphosphate phosphatase within the amidohydrolase superfamily. Biochemistry (2014) 0.77
Identification of family-specific residue packing motifs and their use for structure-based protein function prediction: II. Case studies and applications. J Comput Aided Mol Des (2009) 0.77
Cloning, expression, purification, crystallization and preliminary X-ray characterization of allantoinase from Bacillus licheniformis ATCC 14580. Acta Crystallogr F Struct Biol Commun (2014) 0.76
Function discovery and structural characterization of a methylphosphonate esterase. Biochemistry (2015) 0.76
Active site loop conformation regulates promiscuous activity in a lactonase from Geobacillus kaustophilus HTA426. PLoS One (2015) 0.76
Expression, purification, crystallization and preliminary X-ray diffraction analysis of the dihydroorotase domain of human CAD. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.76
Inhibition of a Putative Dihydropyrimidinase from Pseudomonas aeruginosa PAO1 by Flavonoids and Substrates of Cyclic Amidohydrolases. PLoS One (2015) 0.76
Structural-based mutational analysis of D-aminoacylase from Alcaligenes faecalis DA1. Protein Sci (2002) 0.75
A new synthetic route to N-benzyl carboxamides through the reverse reaction of N-substituted formamide deformylase. Appl Environ Microbiol (2013) 0.75
Identification of a new class of adenosine deaminase from Helicobacter pylori with homologs among diverse taxa. J Bacteriol (2013) 0.75
Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase). Bioorg Med Chem (2016) 0.75
Structure of N-formimino-L-glutamate iminohydrolase from Pseudomonas aeruginosa. Biochemistry (2015) 0.75
Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes. Biochemistry (2013) 0.75
Discovery of a bacterial 5-methylcytosine deaminase. Biochemistry (2014) 0.75
Characterization of the Dihydroorotase from Methanococcus jannaschii. Protein J (2017) 0.75
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