Published in Dis Mon on May 01, 1997
Therapeutic applications of PARP inhibitors: anticancer therapy and beyond. Mol Aspects Med (2013) 1.62
Pathophysiological roles of peroxynitrite in circulatory shock. Shock (2010) 1.10
Tetrahydrobiopterin in cardiovascular health and disease. Antioxid Redox Signal (2014) 1.04
Retracted Characterization of short range DNA looping in endotoxin-mediated transcription of the murine inducible nitric-oxide synthase (iNOS) gene. J Biol Chem (2008) 0.93
Nitric oxide and reactive oxygen species in the pathogenesis of preeclampsia. Int J Mol Sci (2015) 0.85
Osteopontin mediates Stat1 degradation to inhibit iNOS transcription in a cecal ligation and puncture model of sepsis. Surgery (2008) 0.83
Stat1 acetylation inhibits inducible nitric oxide synthase expression in interferon-gamma-treated RAW264.7 murine macrophages. Surgery (2007) 0.82
Curbing inflammation in the ischemic heart disease. Int J Inflam (2013) 0.75
Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med (2001) 2.91
Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J Immunol (1996) 2.55
Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J (2000) 2.53
Selective pharmacological inhibition of distinct nitric oxide synthase isoforms. Biochem Pharmacol (1996) 2.48
Derived pulmonary capillary pressure changes after smoke inhalation in sheep. Crit Care Med (1991) 2.15
Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. J Immunol (1999) 1.99
Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide. Proc Natl Acad Sci U S A (1993) 1.96
Malignant hyperpyrexia with anesthesia. JAMA (1967) 1.93
Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury. Circ Res (1998) 1.80
Total arteriovenous CO2 removal: simplifying extracorporeal support for respiratory failure. Ann Thorac Surg (1997) 1.71
Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure. J Pharmacol Exp Ther (2002) 1.69
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity. Br J Pharmacol (1995) 1.67
Poly (ADP-ribose) synthetase mediates intestinal mucosal barrier dysfunction after mesenteric ischemia. Shock (2000) 1.64
New clinically relevant sheep model of severe respiratory failure secondary to combined smoke inhalation/cutaneous flame burn injury. Crit Care Med (2000) 1.63
Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock. Crit Care Med (1997) 1.61
Effect on mortality of inhalation injury. J Trauma (1986) 1.58
Inosine improves gut permeability and vascular reactivity in endotoxic shock. Crit Care Med (2001) 1.57
Protective effect of tumor necrosis factor-alpha against subsequent endotoxemia in mice is mediated, in part, by interleukin-10. Crit Care Med (2001) 1.55
Does measurement of systolic blood pressure with a pulse oximeter correlate with conventional methods? J Clin Monit (1990) 1.55
Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells. Gastroenterology (1998) 1.54
The dynamics of vascular volume and fluid shifts of lactated Ringer's solution and hypertonic-saline-dextran solutions infused in normovolemic sheep. Anesth Analg (2001) 1.53
Nitric oxide sensitivity of the aconitases. J Biol Chem (1997) 1.51
Effects of a novel guanylyl cyclase inhibitor on the vascular actions of nitric oxide and peroxynitrite in immunostimulated smooth muscle cells and in endotoxic shock. Crit Care Med (1999) 1.49
Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide. J Immunol (1996) 1.48
Intermittent high glucose enhances ICAM-1, VCAM-1, E-selectin and interleukin-6 expression in human umbilical endothelial cells in culture: the role of poly(ADP-ribose) polymerase. J Thromb Haemost (2004) 1.48
Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock. J Immunol (2000) 1.47
Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling. Diabetologia (2007) 1.46
Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury. Circulation (2000) 1.46
Pretreatment with tumor necrosis factor-alpha attenuates arterial hypotension and mortality induced by endotoxin in pigs. Crit Care Med (2000) 1.44
Hypertonic saline dextran produces early (8-12 hrs) fluid sparing in burn resuscitation: a 24-hr prospective, double-blind study in sheep. Crit Care Med (2000) 1.42
Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock. Br J Pharmacol (1993) 1.40
Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase. Circ Res (2001) 1.39
Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation. Immunology (1998) 1.34
Clinical detection of LPS and animal models of endotoxemia. Immunobiology (1993) 1.34
An agonist of adenosine A3 receptors decreases interleukin-12 and interferon-gamma production and prevents lethality in endotoxemic mice. Eur J Pharmacol (1998) 1.29
Inhalation injury in burned patients: effects and treatment. Burns Incl Therm Inj (1988) 1.25
Up-regulation of the parathyroid calcium-sensing receptor after burn injury in sheep: a potential contributory factor to postburn hypocalcemia. Crit Care Med (2000) 1.25
Biology of nitric oxide signaling. Crit Care Med (2000) 1.25
Differentiation of the cardiovascular effects of CI-581. Anesth Analg (1969) 1.24
Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke. Int J Mol Med (2001) 1.24
Pathophysiological analysis of combined burn and smoke inhalation injuries in sheep. Am J Physiol Lung Cell Mol Physiol (2001) 1.23
Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase. Inflamm Res (2001) 1.22
Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase. Gut (1999) 1.19
Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death. J Immunol (1998) 1.18
Protective effects of mercaptoethylguanidine, a selective inhibitor of inducible nitric oxide synthase, in ligature-induced periodontitis in the rat. Br J Pharmacol (1998) 1.18
Regulation of cytokine and chemokine production by transmitters and co-transmitters of the autonomic nervous system. Biochem Pharmacol (1998) 1.17
Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase. Cardiovasc Res (1997) 1.17
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock. Br J Pharmacol (1995) 1.16
Blockade of Poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis. Gastroenterology (1999) 1.15
The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock. Br J Pharmacol (1997) 1.14
Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFkappaB activation. FASEB J (1998) 1.14
Role of nitric oxide in vascular permeability after combined burns and smoke inhalation injury. Am J Respir Crit Care Med (2001) 1.14
Bacterial induction of inducible nitric oxide synthase in cultured human intestinal epithelial cells. Gastroenterology (1998) 1.13
Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation. Free Radic Biol Med (1998) 1.12
Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion. Br J Pharmacol (1997) 1.10
Antiperoxynitrite strategies for the experimental therapy of shock. Crit Care Med (2000) 1.10
Lipocortin 1 protects against splanchnic artery occlusion and reperfusion injury by affecting neutrophil migration. J Immunol (1997) 1.09
Reversal of hyperdynamic response to continuous endotoxin administration by inhibition of NO synthesis. J Appl Physiol (1985) (1992) 1.09
Proinflammatory cytokines depress cardiac efficiency by a nitric oxide-dependent mechanism. Am J Physiol (1998) 1.09
Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells. Diabetes (1997) 1.08
Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation. J Mol Med (Berl) (2001) 1.08
Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy. Diabetologia (2004) 1.08
Effects of NG-nitro-L-arginine and L-arginine on regional cerebral blood flow in the cat. J Physiol (1992) 1.07
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity. J Pineal Res (1997) 1.07
An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice. J Autoimmun (2001) 1.06
Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture. Am J Respir Crit Care Med (2001) 1.05
Bacterial invasion is not required for activation of NF-kappaB in enterocytes. Infect Immun (1999) 1.03
Effect of L-buthionine-(S,R)-sulphoximine, an inhibitor of gamma-glutamylcysteine synthetase on peroxynitrite- and endotoxic shock-induced vascular failure. Br J Pharmacol (1998) 1.03
NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes. J Endocrinol (2002) 1.02
Involvement of the sympathetic nervous system in the pressor response to ketamine. Anesth Analg (1969) 1.02
Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse. Br J Pharmacol (1995) 1.02
Free radical activity and loss of plasma antioxidants, vitamin E, and sulfhydryl groups in patients with burns: the 1993 Moyer Award. J Burn Care Rehabil (1994) 1.02
The pathophysiology of smoke inhalation injury in a sheep model. J Trauma (1984) 1.01
Protection by inhibition of poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts In vitro. J Mol Cell Cardiol (1997) 1.01
Induction and activity of nitric oxide synthase in cultured human intestinal epithelial monolayers. Am J Physiol (1996) 1.00
The crucial role of IL-10 in the suppression of the immunological response in mice exposed to staphylococcal enterotoxin B. Eur J Immunol (1998) 1.00
Pathophysiologic role of oxidative stress-induced poly(ADP-ribose) polymerase-1 activation: focus on cell death and transcriptional regulation. Cell Mol Life Sci (2005) 0.99
Increasing duration of smoke exposure induces more severe lung injury in sheep. J Appl Physiol (1985) (1988) 0.99
A dynamic model of ventricular interaction and pericardial influence. Am J Physiol (1997) 0.98
Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death. FASEB J (2001) 0.98
The effect of leukocyte depletion on smoke inhalation injury in sheep. Surgery (1988) 0.98
Etiology of the pulmonary pathophysiology associated with inhalation injury. Resuscitation (1986) 0.98
Transcriptional regulation of human inducible nitric oxide synthase gene in an intestinal epithelial cell line. Am J Physiol (1997) 0.97
Nicotine reduces the incidence of type I diabetes in mice. J Pharmacol Exp Ther (2002) 0.97
Heparin improves oxygenation and minimizes barotrauma after severe smoke inhalation in an ovine model. Surg Gynecol Obstet (1993) 0.97
Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase. Mol Med (2001) 0.97
Suppression of poly (ADP-ribose) polymerase activation by 3-aminobenzamide in a rat model of myocardial infarction: long-term morphological and functional consequences. Br J Pharmacol (2001) 0.96
ATP suppression of interleukin-12 and tumour necrosis factor-alpha release from macrophages. Br J Pharmacol (2000) 0.96
Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion. Neurosci Lett (1998) 0.96
Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: lessons learned from experimental and clinical studies. Shock (1997) 0.96
Melatonin is a scavenger of peroxynitrite. Life Sci (1997) 0.96
Role of inducible nitric oxide synthase in the regulation of neutrophil migration in zymosan-induced inflammation. Immunology (1998) 0.96
Gut failure and translocation following burn and sepsis. J Surg Res (1994) 0.95
Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-gamma. Shock (2000) 0.95
K(ATP)-channel inhibition improves hemodynamics and cellular energetics in hemorrhagic shock. Am J Physiol (1997) 0.95
Collagen induced arthritis: reversal by mercaptoethylguanidine, a novel antiinflammatory agent with a combined mechanism of action. J Rheumatol (1998) 0.95
Stimulation of beta-adrenoceptors inhibits endotoxin-induced IL-12 production in normal and IL-10 deficient mice. J Neuroimmunol (1998) 0.94