Published in Infect Immun on June 01, 1997
Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell (1989) 13.41
Commentary. Lysosomotropic agents. Biochem Pharmacol (1974) 12.28
Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells. Proc Natl Acad Sci U S A (1988) 10.77
Biological applications of ionophores. Annu Rev Biochem (1976) 9.81
Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J Biol Chem (1992) 4.87
Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae. Cell (1991) 4.17
Bacterial toxins: cellular mechanisms of action. Microbiol Rev (1984) 3.42
The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A. J Biol Chem (1992) 2.40
Defective acidification of endosomes in Chinese hamster ovary cell mutants "cross-resistant" to toxins and viruses. Proc Natl Acad Sci U S A (1983) 2.39
Receptor-mediated internalization of Pseudomonas toxin by mouse fibroblasts. Cell (1980) 2.17
Recombinant toxins as novel therapeutic agents. Annu Rev Biochem (1992) 2.05
Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol. J Biol Chem (1990) 2.04
Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion. J Biol Chem (1993) 1.94
Proteolytic activation of bacterial toxins: role of bacterial and host cell proteases. Infect Immun (1994) 1.61
Disruption of the Golgi apparatus by brefeldin A inhibits the cytotoxicity of ricin, modeccin, and Pseudomonas toxin. Exp Cell Res (1991) 1.60
Cleavage of pseudomonas exotoxin and diphtheria toxin by a furin-like enzyme prepared from beef liver. J Biol Chem (1994) 1.43
Strains of CHO-K1 cells resistant to Pseudomonas exotoxin A and cross-resistant to diphtheria toxin and viruses. Infect Immun (1983) 1.41
Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol. J Biol Chem (1992) 1.38
Toxin entry: how reversible is the secretory pathway? Trends Cell Biol (1992) 1.29
Structure, function, and regulation of Pseudomonas aeruginosa exotoxin A. Annu Rev Microbiol (1990) 1.18
Coat proteins in intracellular membrane transport. Curr Opin Cell Biol (1994) 1.17
A Chinese hamster ovary cell mutant with a heat-sensitive, conditional-lethal defect in vacuolar function. J Cell Biol (1984) 1.16
Receptor-mediated entry of Pseudomonas toxin: methylamine blocks clustering step. Infect Immun (1983) 1.15
Brefeldin-A enhancement of ricin A-chain immunotoxins and blockade of intact ricin, modeccin, and abrin. J Biol Chem (1991) 1.06
Cloning and expression of a gene segment encoding the enzymatic moiety of Pseudomonas aeruginosa exotoxin A. J Bacteriol (1984) 0.95
A dipeptide insertion in domain I of exotoxin A that impairs receptor binding. J Biol Chem (1989) 0.86
The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement. J Cell Biol (1980) 3.64
Diphtheria toxin forms transmembrane channels in planar lipid bilayers. Proc Natl Acad Sci U S A (1981) 3.17
The nature of major histocompatibility complex recognition by gamma delta T cells. Cell (1994) 2.64
Monensin blocks the transport of diphtheria toxin to the cell cytoplasm. J Cell Biol (1982) 1.58
Diphtheria toxin has the properties of a lectin. Proc Natl Acad Sci U S A (1978) 1.36
Biochemical and genetic characterization of three hamster cell mutants resistant to diphtheria toxin. J Cell Biol (1979) 1.26
Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane. Infect Immun (1984) 1.17
A Chinese hamster ovary cell mutant with a heat-sensitive, conditional-lethal defect in vacuolar function. J Cell Biol (1984) 1.16
Transcription and expression of the exotoxin A gene of Pseudomonas aeruginosa. J Gen Microbiol (1987) 1.16
Three new complementation groups of temperature-sensitive Chinese hamster ovary cell mutants defective in the endocytic pathway. Somat Cell Mol Genet (1988) 1.12
A thermosensitive lesion in a Chinese hamster cell mutant causing differential effects on the acidification of endosomes and lysosomes. J Biol Chem (1986) 1.03
Studies of the diphtheria toxin receptor on Chinese hamster cells. J Supramol Struct (1978) 1.00
Cloning and expression of a gene segment encoding the enzymatic moiety of Pseudomonas aeruginosa exotoxin A. J Bacteriol (1984) 0.95
Interaction of coatomer with aminoglycoside antibiotics: evidence that coatomer has at least two dilysine binding sites. Mol Biol Cell (1997) 0.95
Identification of a cold-sensitive step in the mechanism of modeccin action. J Biol Chem (1984) 0.92
Turnover of the transferrin receptor is not influenced by removing most of the extracellular domain. J Biol Chem (1991) 0.91
Inhibition of secretion by 1,3-Cyclohexanebis(methylamine), a dibasic compound that interferes with coatomer function. Mol Biol Cell (1999) 0.90
Impaired lysosomes in a temperature-sensitive mutant of Chinese hamster ovary cells. J Cell Biol (1989) 0.89
Biosynthesis of lysosomal enzymes in cells of the End3 complementation group conditionally defective in endosomal acidification. Somat Cell Mol Genet (1991) 0.89
Retention of secretory proteins in an intermediate compartment and disappearance of the Golgi complex in an END4 mutant of Chinese hamster ovary cells. J Cell Biol (1992) 0.86
A dipeptide insertion in domain I of exotoxin A that impairs receptor binding. J Biol Chem (1989) 0.86
Thermolabile proton translocating ATPase and pump activities in a clathrin-coated vesicle fraction from an acidification defective Chinese hamster cell line. J Biol Chem (1987) 0.86
Purification, molecular weight, amino acid, and subunit composition of arylsulfatase A from human liver. Arch Biochem Biophys (1976) 0.86
Impaired secretion and fluid-phase endocytosis in the End4 mutant of Chinese hamster ovary cells. J Biol Chem (1990) 0.85
Two pathways of transferrin recycling evident in a variant of mouse LMTK- cells. Somat Cell Mol Genet (1988) 0.83
Ricin intoxicates End4 mutants that have an aberrant Golgi complex. J Biol Chem (1993) 0.81
Characterization of a transferrin-diphtheria toxin conjugate. J Biol Chem (1985) 0.81
Defective transport of Sindbis virus glycoproteins in End4 mutant Chinese hamster ovary cells. J Virol (1991) 0.78
Novel method for isolating mammalian cells defective in fluid-phase endocytosis. Somat Cell Mol Genet (1992) 0.78
A variant of exotoxin A that forms potent and specific chemically conjugated immunotoxins. J Biol Chem (1993) 0.75
Pseudomonas aeruginosa exotoxin A. Targeted Diagn Ther (1992) 0.75
Cloning of an enzymatically active segment of the exotoxin-A gene of Pseudomonas aeruginosa. Basic Life Sci (1985) 0.75