Published in Infect Immun on February 01, 1994
Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins. Biochem J (1997) 4.31
Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases. Infect Immun (1995) 2.87
Cleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infection. Proc Natl Acad Sci U S A (2006) 2.64
Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteins. Microbiol Mol Biol Rev (2004) 2.60
Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics. Biol Direct (2012) 2.05
Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain. Science (2008) 1.67
Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives. EMBO J (2000) 1.60
Characterization, genetic analysis, and expression of a protease antigen (PrpRI) of Porphyromonas gingivalis W50. Infect Immun (1995) 1.46
Substrate cleavage analysis of furin and related proprotein convertases. A comparative study. J Biol Chem (2008) 1.40
Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin. Nat Chem Biol (2009) 1.36
A small-molecule furin inhibitor inhibits cancer cell motility and invasiveness. Neoplasia (2008) 1.25
A protein-based therapeutic for human cytomegalovirus infection. Proc Natl Acad Sci U S A (2000) 1.23
Proteomic analysis of the Vibrio cholerae type II secretome reveals new proteins, including three related serine proteases. J Biol Chem (2011) 1.20
Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase. Proc Natl Acad Sci U S A (1999) 1.19
Localization of functional domains of the mitogenic toxin of Pasteurella multocida. Infect Immun (2001) 1.18
Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins. PLoS Pathog (2010) 1.17
A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen. Infect Immun (1997) 1.13
The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. Infect Immun (2002) 1.09
Role of trypsin-like cleavage at arginine 192 in the enzymatic and cytotonic activities of Escherichia coli heat-labile enterotoxin. Infect Immun (1994) 1.05
Clostridium septicum alpha-toxin is proteolytically activated by furin. Infect Immun (1997) 1.04
Furin regulates both the activation of Pseudomonas exotoxin A and the Quantity of the toxin receptor expressed on target cells. Infect Immun (1996) 1.02
Toxin-based therapeutic approaches. Toxins (Basel) (2010) 1.00
Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen. J Mol Biol (2011) 0.91
Proteolytic cleavage of pertussis toxin S1 subunit is not essential for its activity in mammalian cells. BMC Microbiol (2005) 0.91
Inhibition of class II major histocompatibility complex antigen processing by Escherichia coli heat-labile enterotoxin requires an enzymatically active A subunit. Infect Immun (1998) 0.86
Selective and potent furin inhibitors protect cells from anthrax without significant toxicity. Int J Biochem Cell Biol (2010) 0.84
Zinc metalloproteinase ProA directly activates Legionella pneumophila PlaC glycerophospholipid:cholesterol acyltransferase. J Biol Chem (2012) 0.80
Pseudomonas Exotoxin A: optimized by evolution for effective killing. Front Microbiol (2015) 0.80
Functional and structural characterization of Vibrio cholerae extracellular serine protease B, VesB. J Biol Chem (2014) 0.80
Autoproteolytic activation of bacterial toxins. Toxins (Basel) (2010) 0.79
Elevation of vacuolar pH inhibits the cytotoxic activity of furin-cleaved exotoxin A. Infect Immun (1997) 0.78
A sequence and structure based method to predict putative substrates, functions and regulatory networks of endo proteases. PLoS One (2009) 0.77
Furin Cleavage of L2 during Papillomavirus Infection: Minimal Dependence on Cyclophilins. J Virol (2016) 0.76
Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development. Nature (1984) 12.10
Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc Natl Acad Sci U S A (1982) 10.36
Diphtheria toxin. Annu Rev Biochem (1977) 8.44
Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature (1992) 8.39
ompT encodes the Escherichia coli outer membrane protease that cleaves T7 RNA polymerase during purification. J Bacteriol (1988) 6.64
Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process. J Biol Chem (1986) 5.86
Structure and activity of diphtheria toxin. I. Thiol-dependent dissociation of a fraction of toxin into enzymically active and inactive fragments. J Biol Chem (1971) 5.51
Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins. Eur J Biochem (1988) 5.22
Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease. EMBO J (1992) 5.05
Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin. Proc Natl Acad Sci U S A (1992) 4.91
Mammalian subtilisins: the long-sought dibasic processing endoproteases. Cell (1991) 4.91
Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J Biol Chem (1992) 4.87
Characterization of degP, a gene required for proteolysis in the cell envelope and essential for growth of Escherichia coli at high temperature. J Bacteriol (1989) 4.56
Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160. Nature (1992) 4.16
Purification and characterization of a Shigella dysenteriae 1-like toxin produced by Escherichia coli. Infect Immun (1983) 3.85
Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor. Cell (1992) 3.81
The crystal structure of diphtheria toxin. Nature (1992) 3.80
Pathogenesis of shigella diarrhea. XI. Isolation of a shigella toxin-binding glycolipid from rabbit jejunum and HeLa cells and its identification as globotriaosylceramide. J Exp Med (1986) 3.61
Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway. J Biol Chem (1991) 3.50
Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution. Proc Natl Acad Sci U S A (1986) 3.41
Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule. J Biol Chem (1971) 3.27
The new enzymology of precursor processing endoproteases. J Biol Chem (1992) 3.26
Botulinum C2 toxin ADP-ribosylates actin. Nature (1986) 3.16
Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis. Curr Top Microbiol Immunol (1992) 3.03
Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1. J Biol Chem (1987) 3.00
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule. J Biol Chem (1981) 2.79
Purification and characterization of two components of botulinum C2 toxin. Infect Immun (1980) 2.74
Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin. Infect Immun (1988) 2.69
Molecular pharmacology of botulinum toxin and tetanus toxin. Annu Rev Pharmacol Toxicol (1986) 2.66
Subunit structure of Shigella cytotoxin. J Biol Chem (1981) 2.59
Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum. Nature (1992) 2.49
The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A. J Biol Chem (1992) 2.40
A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo. J Biol Chem (1989) 2.31
Secretion, processing and activation of bacterial extracellular proteases. Mol Microbiol (1989) 2.26
Residues 1-254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides. J Biol Chem (1993) 2.23
Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity. Proc Natl Acad Sci U S A (1990) 2.12
Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes. Mol Biol Rep (1990) 2.12
Recombinant toxins as novel therapeutic agents. Annu Rev Biochem (1992) 2.05
Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol. J Biol Chem (1990) 2.04
Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion. J Biol Chem (1993) 1.94
Conformation of protein secreted across bacterial outer membranes: a study of enterotoxin translocation from Vibrio cholerae. Proc Natl Acad Sci U S A (1987) 1.84
pH-dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen. Mol Microbiol (1993) 1.81
Functional expression of furin demonstrating its intracellular localization and endoprotease activity for processing of proalbumin and complement pro-C3. J Biol Chem (1991) 1.76
Serum protease cleavage of Bacillus anthracis protective antigen. J Gen Microbiol (1992) 1.70
Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL. J Biol Chem (1991) 1.61
Disruption of the Golgi apparatus by brefeldin A inhibits the cytotoxicity of ricin, modeccin, and Pseudomonas toxin. Exp Cell Res (1991) 1.60
Separation and characterization of heavy and light chains from Clostridium botulinum type C toxin and their reconstitution. J Biol Chem (1981) 1.58
Activation of Clostridium botulinum type B toxin by an endogenous enzyme. J Bacteriol (1971) 1.49
Botulinum neurotoxins are zinc proteins. J Biol Chem (1992) 1.48
Anthrax toxin protective antigen: low-pH-induced hydrophobicity and channel formation in liposomes. Mol Microbiol (1991) 1.48
Characterization of the diphtheria toxin-resistance system in Chinese hamster ovary cells. Somatic Cell Genet (1979) 1.45
Strains of CHO-K1 cells resistant to Pseudomonas exotoxin A and cross-resistant to diphtheria toxin and viruses. Infect Immun (1983) 1.41
Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol. J Biol Chem (1992) 1.38
ADP-ribosylation of nonmuscle actin with component I of C2 toxin. Biochem Biophys Res Commun (1986) 1.38
A mutant CHO-K1 strain with resistance to Pseudomonas exotoxin A and alphaviruses fails to cleave Sindbis virus glycoprotein PE2. J Virol (1991) 1.33
Activation of botulinum C2 toxin by trypsin. Infect Immun (1987) 1.32
Domain II mutants of Pseudomonas exotoxin deficient in translocation. J Biol Chem (1989) 1.31
Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway. FEBS Lett (1993) 1.31
PACE/furin can process the vitamin K-dependent pro-factor IX precursor within the secretory pathway. J Biol Chem (1993) 1.30
Biochemical and genetic characterization of three hamster cell mutants resistant to diphtheria toxin. J Cell Biol (1979) 1.26
Mechanisms of the cytopathic action of actin-ADP-ribosylating toxins. Mol Microbiol (1992) 1.22
Identity of molecular structure of Shiga-like toxin I (VT1) from Escherichia coli O157:H7 with that of Shiga toxin. Microb Pathog (1988) 1.20
Interaction between Clostridium botulinum neurotoxin and gangliosides. Biochim Biophys Acta (1980) 1.18
Consensus sequence for precursor processing at mono-arginyl sites. Evidence for the involvement of a Kex2-like endoprotease in precursor cleavages at both dibasic and mono-arginyl sites. J Biol Chem (1992) 1.16
Botulinum neurotoxin type A: sequence of amino acids at the N-terminus and around the nicking site. Biochimie (1990) 1.09
Production by Clostridium spiroforme of an iotalike toxin that possesses mono(ADP-ribosyl)transferase activity: identification of a novel class of ADP-ribosyltransferases. Infect Immun (1989) 1.09
Cellular processing of the interleukin-2 fusion toxin DAB486-IL-2 and efficient delivery of diphtheria fragment A to the cytosol of target cells requires Arg194. J Biol Chem (1990) 1.08
Characterization of a cellular protease that cleaves Pseudomonas exotoxin. Infect Immun (1992) 1.01
Specific cleavage of diphtheria toxin by human urokinase. Biochem Biophys Res Commun (1988) 1.00
Construction of a new universal vector for insertional mutagenesis by homologous recombination. Gene (1992) 0.99
Visualizations of binding and internalization of two nonlinked protein components of botulinum C2 toxin in tissue culture cells. Infect Immun (1992) 0.99
Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage. J Biol Chem (1989) 0.98
Structure of tetanus toxin. Demonstration and separation of a specific enzyme converting intracellular tetanus toxin to the extracellular form. J Biol Chem (1979) 0.98
Entry of diphtheria toxin-protein A chimeras into cells. J Biol Chem (1991) 0.94
A recombinant form of Pseudomonas exotoxin directed at the epidermal growth factor receptor that is cytotoxic without requiring proteolytic processing. J Biol Chem (1992) 0.92
Cytotoxicity of a recombinant ricin-A-chain fusion protein containing a proteolytically-cleavable spacer sequence. FEBS Lett (1990) 0.90
Purification and characterization of a protease from Clostridium botulinum type A that nicks single-chain type A botulinum neurotoxin into the di-chain form. J Bacteriol (1990) 0.90
Immunotoxins containing ricin or its A chain. Semin Cell Biol (1991) 0.89
The processing of human proinsulin and chicken proalbumin by rat hepatic vesicles suggests a convertase specific for X-Y-Arg-Arg or Arg-X-Y-Arg sequences. J Biol Chem (1991) 0.87
Immunotoxins and cytokine toxin fusion proteins. Ann N Y Acad Sci (1991) 0.85
Limited proteolysis of tetanus toxin. Relation to activity and identification of cleavage sites. Eur J Biochem (1991) 0.85
Chains and fragments of tetanus toxin, and their contribution to toxicity. J Physiol (Paris) (1990) 0.82
Entry of Shiga toxin into cells. Zentralbl Bakteriol (1993) 0.80
Botulinum neurotoxin type E fragmented with endoproteinase Lys-C reveals the site trypsin nicks and homology with tetanus neurotoxin. Biochimie (1990) 0.79
Limited proteolysis of single-chain tetanus toxin by tissue enzymes, in cultured brain tissue and during retrograde axonal to the spinal cord. Naunyn Schmiedebergs Arch Pharmacol (1991) 0.76
Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor. Science (1998) 10.53
Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells. Proc Natl Acad Sci U S A (1982) 10.36
Crystal structure of the anthrax toxin protective antigen. Nature (1997) 6.63
Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin. Proc Natl Acad Sci U S A (1992) 4.91
Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J Biol Chem (1992) 4.87
Crystal structure of the anthrax lethal factor. Nature (2001) 3.75
Large-scale purification and characterization of the exotoxin of Pseudomonas aeruginosa. Infect Immun (1976) 3.45
Sequence and analysis of the DNA encoding protective antigen of Bacillus anthracis. Gene (1988) 3.10
Production and purification of anthrax toxin. Methods Enzymol (1988) 3.04
Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases. Infect Immun (1995) 2.87
Bacillus anthracis calmodulin-dependent adenylate cyclase: chemical and enzymatic properties and interactions with eucaryotic cells. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 2.86
Immunoelectrophoretic analysis, toxicity, and kinetics of in vitro production of the protective antigen and lethal factor components of Bacillus anthracis toxin. Infect Immun (1984) 2.70
Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin. Infect Immun (1988) 2.69
Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity. Mol Microbiol (1994) 2.65
Immunization studies with attenuated strains of Bacillus anthracis. Infect Immun (1986) 2.63
Production and characterization of monoclonal antibodies to the protective antigen component of Bacillus anthracis toxin. Infect Immun (1988) 2.63
Optimized production and purification of Bacillus anthracis lethal factor. Protein Expr Purif (2000) 2.52
Cloning and characterization of a gene whose product is a trans-activator of anthrax toxin synthesis. J Bacteriol (1993) 2.46
Cloning of the protective antigen gene of Bacillus anthracis. Cell (1983) 2.31
A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo. J Biol Chem (1989) 2.31
Residues 1-254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides. J Biol Chem (1993) 2.23
Characterization of the subunit structure of the ribonucleic acid genome of influenza virus. J Virol (1971) 2.22
Characterization of lethal factor binding and cell receptor binding domains of protective antigen of Bacillus anthracis using monoclonal antibodies. Microbiology (1996) 2.16
Association of diphtheria toxin with Vero cells. Demonstration of a receptor. J Biol Chem (1978) 2.13
Inhibition of protein synthesis by Shiga toxin: activation of the toxin and inhibition of peptide elongation. FEBS Lett (1980) 2.05
Characterization of macrophage sensitivity and resistance to anthrax lethal toxin. Infect Immun (1993) 1.97
Receptor-mediated internalization and degradation of diphtheria toxin by monkey kidney cells. J Biol Chem (1979) 1.94
Internalization and processing of Bacillus anthracis lethal toxin by toxin-sensitive and -resistant cells. J Biol Chem (1989) 1.93
Nucleotide sequence of the Bacillus anthracis edema factor gene (cya): a calmodulin-dependent adenylate cyclase. Gene (1988) 1.90
Transcriptional regulation of the protective antigen gene of Bacillus anthracis. Infect Immun (1989) 1.86
Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells. Infect Immun (1994) 1.84
Production and characterization of monoclonal antibodies against the lethal factor component of Bacillus anthracis lethal toxin. Infect Immun (1990) 1.78
Production, recovery and immunogenicity of the protective antigen from a recombinant strain of Bacillus anthracis. J Ind Microbiol Biotechnol (2002) 1.75
Protection against anthrax lethal toxin challenge by genetic immunization with a plasmid encoding the lethal factor protein. Infect Immun (2001) 1.75
Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent anthrax toxin. J Biol Chem (2001) 1.73
Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells. J Biol Chem (1992) 1.71
Identification of a receptor-binding region within domain 4 of the protective antigen component of anthrax toxin. Infect Immun (1999) 1.68
Internalization of a Bacillus anthracis protective antigen-c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies. Mol Med (1998) 1.64
Antibodies to anthrax toxin in humans and guinea pigs and their relevance to protective immunity. Med Microbiol Immunol (1988) 1.61
Oligomerization of anthrax toxin protective antigen and binding of lethal factor during endocytic uptake into mammalian cells. Infect Immun (1999) 1.58
The pore-forming toxin proaerolysin is activated by furin. J Biol Chem (1998) 1.54
Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis. J Biol Chem (1991) 1.52
Molecular cloning and expression in Escherichia coli of the lethal factor gene of Bacillus anthracis. Gene (1986) 1.51
Purification and characterization of adenylyl cyclase from Bacillus anthracis. Methods Enzymol (1991) 1.48
The chymotrypsin-sensitive site, FFD315, in anthrax toxin protective antigen is required for translocation of lethal factor. J Biol Chem (1994) 1.47
Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin. Cancer Res (2000) 1.43
The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity. J Biol Chem (1991) 1.41
Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells. J Biol Chem (1989) 1.39
Phosphatidylcholine-specific phospholipase C and sphingomyelinase activities in bacteria of the Bacillus cereus group. Infect Immun (2003) 1.37
Proteasome activity is required for anthrax lethal toxin to kill macrophages. Infect Immun (1999) 1.32
Calcium is required for the expression of anthrax lethal toxin activity in the macrophagelike cell line J774A.1. Infect Immun (1989) 1.31
Suppression of ras-mediated transformation and inhibition of tumor growth and angiogenesis by anthrax lethal factor, a proteolytic inhibitor of multiple MEK pathways. Proc Natl Acad Sci U S A (2001) 1.28
Clostridium septicum alpha toxin uses glycosylphosphatidylinositol-anchored protein receptors. J Biol Chem (1999) 1.26
The exotoxin P. aeruginosa: a proenzyme having an unusual mode of activation. Biochem Biophys Res Commun (1978) 1.25
Protection against anthrax toxin by vaccination with a DNA plasmid encoding anthrax protective antigen. Vaccine (1999) 1.20
Functional characterization of protease-treated Bacillus anthracis protective antigen. J Biol Chem (1992) 1.20
A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen. Infect Immun (1997) 1.13
Cytotoxic effects of a chimeric protein consisting of tetanus toxin light chain and anthrax toxin lethal factor in non-neuronal cells. J Biol Chem (1994) 1.10
Study of immunization against anthrax with the purified recombinant protective antigen of Bacillus anthracis. Infect Immun (1998) 1.10
Effects of lectins on the interaction of diphtheria toxin with mammalian cells. Exp Cell Res (1979) 1.09
Targeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp120-anthrax toxin fusion protein. Proc Natl Acad Sci U S A (1997) 1.09
Protection against experimental Pseudomonas aeruginosa infection in mice by active immunization with exotoxin A toxoids. Infect Immun (1981) 1.08
Furin is important but not essential for the proteolytic maturation of gp160 of HIV-1. FEBS Lett (1995) 1.07
Clostridium septicum alpha-toxin is proteolytically activated by furin. Infect Immun (1997) 1.04
Anthrax toxin components stimulate chemotaxis of human polymorphonuclear neutrophils. Proc Soc Exp Biol Med (1985) 1.04
Structure-function analysis of Bacillus anthracis edema factor by using monoclonal antibodies. Biochem Biophys Res Commun (1994) 1.04
Furin regulates both the activation of Pseudomonas exotoxin A and the Quantity of the toxin receptor expressed on target cells. Infect Immun (1996) 1.02
A dominant-negative therapy for anthrax. Nat Med (2001) 0.95
Evaluation of Pseudomonas aeruginosa toxin A in experimental rat burn wound sepsis. Infect Immun (1979) 0.92
Delivery of antigens to the MHC class I pathway using bacterial toxins. Hum Immunol (1997) 0.89
Comparison of the 3' termini of discrete segments of the double-stranded ribonucleic acid genomes of cytoplasmic polyhedrosis virus, wound tumor virus, and reovirus. J Virol (1972) 0.88
Crystallization of the protective antigen protein of Bacillus anthracis. J Biol Chem (1985) 0.85
In vitro processing of anthrax toxin protective antigen by recombinant PC1 (SPC3) and bovine intermediate lobe secretory vesicle membranes. Arch Biochem Biophys (1995) 0.85
Effect of ammonium chloride on receptor-mediated uptake of diphtheria toxin by Vero cells. Exp Cell Res (1981) 0.84
Separation of three exotoxic factors of Bacillus anthracis by sequential immunosorbent chromatography. Toxicon (1988) 0.81
Induction of hepatitis C virus-specific cytotoxic T lymphocytes in mice by immunization with dendritic cells treated with an anthrax toxin fusion protein. Vaccine (2001) 0.80