Plasmodium falciparum CTP:phosphocholine cytidylyltransferase expressed in Escherichia coli: purification, characterization and lipid regulation.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 1218507)

Published in Biochem J on June 15, 1997

Authors

H J Yeo1, M P Larvor, M L Ancelin, H J Vial

Author Affiliations

1: Laboratoire de Dynamique Moléculaire des Interactions Membranaires, CNRS UMR 5539, Université Montpellier II, case 107, 34095 Montpellier Cedex 5, France.

Articles cited by this

Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81

A rapid method of total lipid extraction and purification. Can J Biochem Physiol (1959) 173.74

"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem (1981) 71.15

Phosphorus assay in column chromatography. J Biol Chem (1959) 60.56

Use of bacteriophage T7 lysozyme to improve an inducible T7 expression system. J Mol Biol (1991) 5.81

Signaling through phosphatidylcholine breakdown. J Biol Chem (1990) 5.36

The regulation and cellular functions of phosphatidylcholine hydrolysis. Biochem J (1990) 3.44

Phospholipid biosynthesis in yeast. Annu Rev Biochem (1989) 2.58

Identification of a non-mitochondrial phosphatidylserine decarboxylase activity (PSD2) in the yeast Saccharomyces cerevisiae. J Biol Chem (1995) 1.91

Genetic regulation of phospholipid biosynthesis in Saccharomyces cerevisiae. Microbiol Rev (1996) 1.77

Coordination of membrane phospholipid synthesis with the cell cycle. J Biol Chem (1994) 1.67

Inhibition of pyrimidine biosynthesis de novo in Plasmodium falciparum by 2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone in vitro. Mol Biochem Parasitol (1985) 1.54

Malarial lipids. An overview. Subcell Biochem (1992) 1.35

Quaternary ammonium compounds efficiently inhibit Plasmodium falciparum growth in vitro by impairment of choline transport. Antimicrob Agents Chemother (1986) 1.27

Regulation of CTP:phosphocholine cytidylyltransferase by lipids. 2. Surface curvature, acyl chain length, and lipid-phase dependence for activation. Biochemistry (1991) 1.25

Genetic analysis of yeast phospholipid biosynthesis. Annu Rev Genet (1991) 1.22

Regulation of phospholipid biosynthesis in the yeast Saccharomyces cerevisiae. J Biol Chem (1996) 1.22

The purification and characterization of CTP:phosphorylcholine cytidylyltransferase from rat liver. J Biol Chem (1986) 1.22

Regulation of phosphatidylcholine biosynthesis in Plasmodium-infected erythrocytes. Biochim Biophys Acta (1989) 1.19

Molecular cloning and characterization of the gene encoding cholinephosphate cytidylyltransferase in Saccharomyces cerevisiae. Eur J Biochem (1987) 1.17

Translocation of CTP: phosphocholine cytidylyltransferase from cytosol to membranes in HeLa cells: stimulation by fatty acid, fatty alcohol, mono- and diacylglycerol. Biochim Biophys Acta (1987) 1.16

Sphingosine inhibits the activity of rat liver CTP:phosphocholine cytidylyltransferase. J Biol Chem (1990) 1.12

CTP:phosphorylcholine cytidylyltransferase in rat lung. The effect of free fatty acids on the translocation of activity between microsomes and cytosol. J Biol Chem (1984) 1.11

Cloning and expression of rat liver CTP: phosphocholine cytidylyltransferase: an amphipathic protein that controls phosphatidylcholine synthesis. Proc Natl Acad Sci U S A (1990) 1.09

Lipid regulation of CTP: phosphocholine cytidylyltransferase: electrostatic, hydrophobic, and synergistic interactions of anionic phospholipids and diacylglycerol. Biochemistry (1996) 1.04

Functional redundancy of CDP-ethanolamine and CDP-choline pathway enzymes in phospholipid biosynthesis: ethanolamine-dependent effects on steady-state membrane phospholipid composition in Saccharomyces cerevisiae. J Bacteriol (1994) 1.04

Phosphatidylcholine biosynthesis via the CDP-choline pathway in Saccharomyces cerevisiae. Multiple mechanisms of regulation. J Biol Chem (1994) 1.03

Regulation of CTP:phosphocholine cytidylyltransferase in HeLa cells. Effect of oleate on phosphorylation and intracellular localization. J Biol Chem (1993) 1.03

Regulation of CTP:phosphocholine cytidylyltransferase by lipids. 1. Negative surface charge dependence for activation. Biochemistry (1991) 1.02

Effects of altered phosphorylation sites on the properties of CTP:phosphocholine cytidylyltransferase. J Biol Chem (1995) 1.02

Identification of an inhibitory domain of CTP:phosphocholine cytidylyltransferase. J Biol Chem (1995) 1.00

Dephosphorylation of CTP-phosphocholine cytidylyltransferase is not required for binding to membranes. J Biol Chem (1994) 0.99

Identification of the membrane-binding domain of rat liver CTP:phosphocholine cytidylyltransferase using chymotrypsin proteolysis. J Biol Chem (1994) 0.99

Evidence that binding of CTP:phosphocholine cytidylyltransferase to membranes in rat hepatocytes is modulated by the ratio of bilayer- to non-bilayer-forming lipids. Biochem J (1993) 0.98

The association of lipid activators with the amphipathic helical domain of CTP:phosphocholine cytidylyltransferase accelerates catalysis by increasing the affinity of the enzyme for CTP. J Biol Chem (1995) 0.97

CTP:phosphorylcholine cytidylyltransferase from rat liver. Isolation and characterization of the catalytic subunit. J Biol Chem (1987) 0.96

Lipid activation of CTP:phosphocholine cytidylyltransferase is regulated by the phosphorylated carboxyl-terminal domain. J Biol Chem (1995) 0.93

Functions of the C-terminal domain of CTP: phosphocholine cytidylyltransferase. Effects of C-terminal deletions on enzyme activity, intracellular localization and phosphorylation potential. Biochem J (1995) 0.92

Membrane-binding amphipathic alpha-helical peptide derived from CTP:phosphocholine cytidylyltransferase. Biochemistry (1994) 0.90

Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by CTP. J Biol Chem (1995) 0.90

Baculovirus-mediated expression of rat liver CTP:phosphocholine cytidylyltransferase. Protein Expr Purif (1993) 0.88

On the mechanism of the okadaic acid-induced inhibition of phosphatidylcholine biosynthesis in isolated rat hepatocytes. J Biol Chem (1992) 0.88

Expression of wild-type and mutant rat liver CTP: phosphocholine cytidylyltransferase in a cytidylyltransferase-deficient Chinese hamster ovary cell line. Arch Biochem Biophys (1994) 0.87

Choline-phosphate cytidylyltransferase. Methods Enzymol (1992) 0.87

Primary structure and expression of a human CTP:phosphocholine cytidylyltransferase. Biochim Biophys Acta (1994) 0.85

Increased expression of CTP:phosphocholine cytidylyltransferase in maturing type II cells. Am J Physiol (1994) 0.85

Regulation of CTP:phosphocholine cytidylyltransferase activity and subcellular location by phosphorylation in Chinese hamster ovary cells. The effect of phospholipase C treatment. J Biol Chem (1991) 0.85

Comparison of the lipid regulation of yeast and rat CTP: phosphocholine cytidylyltransferase expressed in COS cells. Biochem J (1992) 0.85

Molecular cloning of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum. Eur J Biochem (1995) 0.82

Articles by these authors

Use of radioactive ethanolamine incorporation into phospholipids to assess in vitro antimalarial activity by the semiautomated microdilution technique. Antimicrob Agents Chemother (1992) 1.96

Antimalarial activity of compounds interfering with Plasmodium falciparum phospholipid metabolism: comparison between mono- and bisquaternary ammonium salts. J Med Chem (2000) 1.50

The neuroprotective effects of caffeine: a prospective population study (the Three City Study). Neurology (2007) 1.47

Malarial lipids. An overview. Subcell Biochem (1992) 1.35

Quaternary ammonium compounds efficiently inhibit Plasmodium falciparum growth in vitro by impairment of choline transport. Antimicrob Agents Chemother (1986) 1.27

Antimalarial activity of 77 phospholipid polar head analogs: close correlation between inhibition of phospholipid metabolism and in vitro Plasmodium falciparum growth. Blood (1998) 1.24

Biosynthesis and dynamics of lipids in Plasmodium-infected mature mammalian erythrocytes. Blood Cells (1990) 1.21

Regulation of phosphatidylcholine biosynthesis in Plasmodium-infected erythrocytes. Biochim Biophys Acta (1989) 1.19

Antimalarial activity of molecules interfering with Plasmodium falciparum phospholipid metabolism. Structure-activity relationship analysis. J Med Chem (1997) 1.15

Phospholipid biosynthesis in synchronous Plasmodium falciparum cultures. J Protozool (1982) 1.14

Phospholipid metabolism of serine in Plasmodium-infected erythrocytes involves phosphatidylserine and direct serine decarboxylation. Biochem J (1997) 1.12

Increased permeability to choline in simian erythrocytes after Plasmodium knowlesi infection. Biochem J (1991) 1.10

A reevaluation of the status of cholesterol in erythrocytes infected by Plasmodium knowlesi and P. falciparum. Mol Biochem Parasitol (1984) 1.09

Phospholipid biosynthesis by Plasmodium knowlesi-infected erythrocytes: the incorporation of phospohlipid precursors and the identification of previously undetected metabolic pathways. J Parasitol (1982) 1.08

Differential in vitro activities of ionophore compounds against Plasmodium falciparum and mammalian cells. Antimicrob Agents Chemother (1996) 1.07

Characterization of the potent in vitro and in vivo antimalarial activities of ionophore compounds. Antimicrob Agents Chemother (1997) 1.06

A prospective study of diurnal cortisol and cognitive function in community-dwelling elderly people. Psychol Med (2009) 1.04

Characteristics of hormone therapy, cognitive function, and dementia: the prospective 3C Study. Neurology (2009) 1.03

Phospholipid metabolism as a new target for malaria chemotherapy. Mechanism of action of D-2-amino-1-butanol. Biochem Pharmacol (1984) 0.97

Characterization of phosphatidylinositol synthase and evidence of a polyphosphoinositide cycle in Plasmodium-infected erythrocytes. Mol Biochem Parasitol (1994) 0.95

Phospholipid uptake by Plasmodium knowlesi infected erythrocytes. FEBS Lett (1988) 0.94

Selective elimination of malaria infected erythrocytes by a modified phospholipase A2 in vitro. Biochim Biophys Acta (1990) 0.89

Phospholipid metabolism in Plasmodium-infected erythrocytes: guidelines for further studies using radioactive precursor incorporation. Parasitology (1989) 0.88

Inhibitors of choline transport into Plasmodium-infected erythrocytes are effective antiplasmodial compounds in vitro. Biochem Pharmacol (1985) 0.88

Choline kinase activity in Plasmodium-infected erythrocytes: characterization and utilization as a parasite-specific marker in malarial fractionation studies. Biochim Biophys Acta (1986) 0.88

Exploring metabolomic approaches to analyse phospholipid biosynthetic pathways in Plasmodium. Parasitology (2010) 0.87

Cholinephosphotransferase and ethanolaminephosphotransferase activities in Plasmodium knowlesi-infected erythrocytes. Their use as parasite-specific markers. Biochim Biophys Acta (1984) 0.85

Several lines of evidence demonstrating that Plasmodium falciparum, a parasitic organism, has distinct enzymes for the phosphorylation of choline and ethanolamine. FEBS Lett (1986) 0.84

Uninfected red cells from malaria-infected blood: alteration of fatty acid composition involving a serum protein: an in vivo and in vitro study. In Vitro Cell Dev Biol (1988) 0.83

Modification of the fatty acid composition of individual phospholipids and neutral lipids after infection of the simian erythrocyte by Plasmodium knowlesi. Biochim Biophys Acta (1986) 0.83

Inhibition of the in vitro growth of Plasmodium falciparum by D vitamins and vitamin D-3 derivatives. Mol Biochem Parasitol (1982) 0.83

Molecular cloning of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum. Eur J Biochem (1995) 0.82

An original method for rapid serial determination of phospholipid biosynthesis. Applications to mammalian lymphocytic cells and a lower eucaryote, Plasmodium falciparum. Anal Biochem (1991) 0.82

Acyl-CoA synthetase activity in Plasmodium knowlesi-infected erythrocytes displays peculiar substrate specificities. Biochim Biophys Acta (1988) 0.82

Saturable and non-saturable components of choline transport in Plasmodium-infected mammalian erythrocytes: possible role of experimental conditions. Biochem J (1992) 0.82

Reevaluation, using marker enzymes, of the ability of saponin and ammonium chloride to free Plasmodium from infected erythrocytes. J Parasitol (1987) 0.82

A quantitative liquid chromatography tandem mass spectrometry method for metabolomic analysis of Plasmodium falciparum lipid related metabolites. Anal Chim Acta (2012) 0.81

Progestins and androgens stimulate lipid accumulation in T47D breast cancer cells via their own receptors. J Steroid Biochem (1989) 0.80

Cationomycin and monensin partition between serum proteins and erythrocyte membrane: consequences for Na+ and K+ transport and antimalarial activities. Arch Biochem Biophys (1999) 0.80

Quantitative analysis of a bis-thiazolium antimalarial compound, SAR97276, in mouse plasma and red blood cell samples, using liquid chromatography mass spectrometry. J Pharm Biomed Anal (2007) 0.80

Continuous in vitro culture of Babesia divergens in a serum-free medium. Parasitology (1997) 0.79

Plasmodium knowlesi induces alterations in phosphatidylcholine and phosphatidylethanolamine molecular species composition of parasitized monkey erythrocytes. Biochim Biophys Acta (1990) 0.79

Transport of phospholipid synthesis precursors and lipid trafficking into malaria-infected erythrocytes. Novartis Found Symp (1999) 0.78

Phospholipid asymmetry in the plasma membrane of malaria infected erythrocytes. Biochem Cell Biol (1990) 0.77

Enhanced transbilayer mobility of phospholipids in malaria-infected monkey erythrocytes: a spin-label study. J Cell Physiol (1988) 0.77

Differential effects of chloroquine on the phospholipid metabolism of Plasmodium-infected erythrocytes. Biochem Pharmacol (1988) 0.77

Present development concerning antimalarial activity of phospholipid metabolism inhibitors with special reference to in vivo activity. Mem Inst Oswaldo Cruz (1994) 0.77

Choline incorporation by Schistosoma mansoni: distribution of choline metabolites during development and after sexual differentiation. J Parasitol (1987) 0.76

Correlation of the efficiency of fatty acid derivatives in suppressing Plasmodium falciparum growth in culture with their inhibitory effect on acyl-CoA synthetase activity. Mol Biochem Parasitol (1988) 0.76

Modelling complex pathways between late-life depression and disability: evidence for mediating and moderating factors. Psychol Med (2009) 0.75

[Epidemiology of mental diseases in the elderly]. Encephale (2006) 0.75

1H-NMR conformational analysis of a high-affinity antigenic 11-residue peptide from the tryptophan synthase beta 2 subunit. Eur J Biochem (1991) 0.75

Infected erythrocyte choline carrier inhibitors: exploring some potentialities inside Plasmodium phospholipid metabolism for eventual resistance acquisition. Mem Inst Oswaldo Cruz (1994) 0.75

Renewed strategies for drug development against parasitic diseases. Parasitol Today (1999) 0.75

[Research for new antimalarial molecules: an emergency, a hope]. Pathol Biol (Paris) (1994) 0.75

Rapid resolution liquid chromatography-mass spectrometry determination of SAR97276 in monkey matrices. Pharmacokinetics in rhesus monkey infected by Plasmodium cynomolgi. J Pharm Biomed Anal (2009) 0.75

A liquid chromatography-mass spectrometry assay for simultaneous determination of two antimalarial thiazolium compounds in human and rat matrices. J Pharm Biomed Anal (2008) 0.75

The design of original antimalarial drugs. An example of phospholipid metabolism. Parassitologia (1993) 0.75

Quantitative analysis of fatty acid methyl esters and dimethyl acetals on a polar (free fatty acid phase) capillary column. J Chromatogr (1986) 0.75

Total cholesterol, fatty acids, and plasmalogens can be reliably quantitated by analysis on chromarods after the methylation step required for fatty acid analysis by gas-liquid chromatography. Anal Biochem (1986) 0.75

Renewal of the membrane complex of Schistosoma mansoni is closely associated with lipid metabolism. Mol Biochem Parasitol (1985) 0.75

Rapid and serial determination of protein kinase C activity and of the associated [3H]PDBu binding using a 96-well microtiter plate and a cell harvester. Anal Biochem (1990) 0.75