S L Berger

Author PubWeight™ 170.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev 2000 9.36
2 Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev 1997 8.35
3 Expression of human immune interferon cDNA in E. coli and monkey cells. Nature 1982 6.55
4 Inhibition of intractable nucleases with ribonucleoside--vanadyl complexes: isolation of messenger ribonucleic acid from resting lymphocytes. Biochemistry 1979 6.00
5 The TAF(II)250 subunit of TFIID has histone acetyltransferase activity. Cell 1996 5.20
6 p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. Mol Cell Biol 1999 4.88
7 BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. Oncogene 1998 4.88
8 Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol Cell 2001 4.73
9 Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell 2000 4.05
10 Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction. Mol Cell Biol 1999 3.90
11 First-strand cDNA synthesis primed with oligo(dT). Methods Enzymol 1987 3.06
12 Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors. EMBO J 1994 3.00
13 Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo. Genes Dev 1998 2.76
14 Snf1--a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. Science 2001 2.58
15 Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo. EMBO J 1997 2.58
16 Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature 1999 2.50
17 Preparation of cDNA and the generation of cDNA libraries: overview. Methods Enzymol 1987 2.40
18 Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein. J Biol Chem 1995 2.37
19 Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5. Mol Cell Biol 1996 2.30
20 The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes. Trends Cell Biol 1998 2.28
21 Catalytic mechanism and function of invariant glutamic acid 173 from the histone acetyltransferase GCN5 transcriptional coactivator. J Biol Chem 1999 2.13
22 Structural and functional analysis of yeast putative adaptors. Evidence for an adaptor complex in vivo. J Biol Chem 1996 2.01
23 Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters. Mol Cell Biol 2000 2.00
24 The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae. Mol Cell Biol 1999 2.00
25 Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator. Proc Natl Acad Sci U S A 1999 1.99
26 Gene expression during reactivation of herpes simplex virus type 1 from latency in the peripheral nervous system is different from that during lytic infection of tissue cultures. J Virol 1997 1.86
27 Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation. Mol Cell Biol 1997 1.85
28 During lytic infection herpes simplex virus type 1 is associated with histones bearing modifications that correlate with active transcription. J Virol 2004 1.84
29 Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases. Mol Cell 2000 1.80
30 Differential activation of RNA polymerase III-transcribed genes by the polyomavirus enhancer and the adenovirus E1A gene products. Nucleic Acids Res 1985 1.72
31 Absence of Gcn5 HAT activity defines a novel state in the opening of chromatin at the PHO5 promoter in yeast. Mol Cell 1998 1.71
32 Two tandem and independent sub-activation domains in the amino terminus of p53 require the adaptor complex for activity. Oncogene 1997 1.70
33 CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein. Cancer Res 1997 1.70
34 Ribonuclease H activities associated with viral reverse transcriptases are endonucleases. Proc Natl Acad Sci U S A 1989 1.67
35 A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. Mol Cell 1999 1.55
36 Histone acetyltransferase complexes. Semin Cell Dev Biol 1999 1.52
37 Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol Cell Biol 1998 1.50
38 Nucleotides in the polyomavirus enhancer that control viral transcription and DNA replication. Mol Cell Biol 1987 1.48
39 Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members. Nucleic Acids Res 1998 1.47
40 The human prothymosin alpha gene is polymorphic and induced upon growth stimulation: evidence using a cloned cDNA. Proc Natl Acad Sci U S A 1986 1.43
41 Molecular hybridization of immobilized nucleic acids: theoretical concepts and practical considerations. Methods Enzymol 1987 1.43
42 Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A. EMBO J 1999 1.39
43 Isolation of cytoplasmic RNA: ribonucleoside-vanadyl complexes. Methods Enzymol 1987 1.30
44 Development and characterization of an in vivo pathogenic molecular clone of equine infectious anemia virus. J Virol 1998 1.22
45 Reverse transcriptase and its associated ribonuclease H: interplay of two enzyme activities controls the yield of single-stranded complementary deoxyribonucleic acid. Biochemistry 1983 1.22
46 Structure and function of bromodomains in chromatin-regulating complexes. Gene 2001 1.15
47 Screening colonies or plaques with radioactive nucleic acid probes. Methods Enzymol 1987 1.13
48 Very short-lived and stable mRNAs from resting human lymphocytes. Proc Natl Acad Sci U S A 1975 1.13
49 Homopolymeric tailing. Methods Enzymol 1987 1.12
50 Isolation and partial sequencing of the human prothymosin alpha gene family. Evidence against export of the gene products. J Biol Chem 1989 1.11
51 GCN5 and ADA adaptor proteins regulate triiodothyronine/GRIP1 and SRC-1 coactivator-dependent gene activation by the human thyroid hormone receptor. Mol Endocrinol 2000 1.11
52 Activation of chromosomal DNA replication in Saccharomyces cerevisiae by acidic transcriptional activation domains. Mol Cell Biol 1998 1.08
53 Enhanced sensitivity to neutralizing antibodies in a variant of equine infectious anemia virus is linked to amino acid substitutions in the surface unit envelope glycoprotein. J Virol 1995 1.07
54 Prothymosin alpha antisense oligomers inhibit myeloma cell division. Proc Natl Acad Sci U S A 1991 1.07
55 Quantifying 32P-labeled and unlabeled nucleic acids. Methods Enzymol 1987 1.06
56 Isolation of RNA. Methods Enzymol 1989 1.04
57 Nuclear targeting of prothymosin alpha. J Biol Chem 1991 1.01
58 Identification and analysis of native nucleosomal histone acetyltransferase complexes. Methods Mol Biol 1999 1.00
59 Interplay between chromatin modifying and remodeling complexes in transcriptional regulation. Crit Rev Eukaryot Gene Expr 1999 0.99
60 Effect of ribonucleoside-vanadyl complexes on enzyme-catalyzed reactions central to recombinant deoxyribonucleic acid technology. Biochemistry 1982 0.98
61 Reverse transcriptase from human immunodeficiency virus: a single template-primer binding site serves two physically separable catalytic functions. Biochemistry 1991 0.95
62 Diethyl pyrocarbonate: an examination of its properties in buffered solutions with a new assay technique. Anal Biochem 1975 0.93
63 GAG triplets as splice acceptors of last resort. An unusual form of alternative splicing in prothymosin alpha pre-mRNA. J Mol Biol 1993 0.91
64 Preparation of interferon messenger RNAs with the use of ribonucleoside--vanadyl complexes. Methods Enzymol 1981 0.90
65 Gene regulation. Local or global? Nature 2000 0.90
66 Lymphocytes as resting cells. Methods Enzymol 1979 0.90
67 Histone H2B ubiquitylation and deubiquitylation in genomic regulation. Cold Spring Harb Symp Quant Biol 2004 0.89
68 Characterization of interferon messenger RNA synthesis in Namalva cells. J Biol Chem 1980 0.89
69 Preparation and characterization of RNA: overview. Methods Enzymol 1987 0.88
70 Free ribosomes in physiologically nondividing cells. Human peripheral lymphocytes. J Biol Chem 1976 0.88
71 The human transcriptional adaptor genes TADA2L and GCN5L2 colocalize to chromosome 17q12-q21 and display a similar tissue expression pattern. Genomics 1997 0.87
72 The human prothymosin alpha gene family contains several processed pseudogenes lacking deleterious lesions. Genomics 1992 0.86
73 Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model. Cell Death Differ 2013 0.86
74 Use of differential display reverse transcription-PCR to reveal cellular changes during stimuli that result in herpes simplex virus type 1 reactivation from latency: upregulation of immediate-early cellular response genes TIS7, interferon, and interferon regulatory factor-1. J Virol 1998 0.85
75 Purification of large double-stranded cDNA fragments. Methods Enzymol 1987 0.85
76 Turnover of the acyl phosphates of human and murine prothymosin alpha in vivo. J Biol Chem 1997 0.84
77 Histone post-translational modifications regulate transcription and silent chromatin in Saccharomyces cerevisiae. Ernst Schering Res Found Workshop 2006 0.83
78 Functional discontinuities in prothymosin alpha caused by caspase cleavage in apoptotic cells. J Cell Physiol 2000 0.82
79 A micromethod for measuring the molar concentration of polyadenylated RNA in the presence of ribosomal RNA. Anal Biochem 1986 0.82
80 The use of Cerenkov radiation for monitoring reactions performed in minute volumes: examples from recombinant DNA technology. Anal Biochem 1984 0.82
81 The acidic transcriptional activation domains of herpes virus VP16 and yeast HAP4 have different co-factor requirements. Gene 1995 0.82
82 Prothymosin alpha is a nonspecific facilitator of nuclear processes: studies of run-on transcription. Protein Expr Purif 2000 0.81
83 Prothymosin alpha in vivo contains phosphorylated glutamic acid residues. J Biol Chem 1997 0.81
84 Human prothymosin alpha: purification of a highly acidic nuclear protein by means of a phenol extraction. Protein Expr Purif 1990 0.81
85 Direct mapping of rare messenger RNAs by means of oligomer-directed ribonuclease H cleavage. Anal Biochem 1987 0.81
86 Interferon enhancement of the invasive capacity of Ewing sarcoma cells in vitro. Proc Natl Acad Sci U S A 1982 0.80
87 Gene array analysis reveals changes in peripheral nervous system gene expression following stimuli that result in reactivation of latent herpes simplex virus type 1: induction of transcription factor Bcl-3. J Virol 2001 0.80
88 Mobility within the nucleus and neighboring cytosol is a key feature of prothymosin-alpha. J Histochem Cytochem 2000 0.80
89 Do products of the myc proto-oncogene play a role in transcriptional regulation of the prothymosin alpha gene? Mol Cell Biol 1995 0.79
90 Translation of human immune interferon messenger RNA in Xenopus laevis oocytes. Biochem Biophys Res Commun 1981 0.79
91 Phosphorylation of human and bovine prothymosin alpha in vivo. Biochemistry 1993 0.78
92 Does prothymosin alpha affect the phosphorylation of elongation factor 2? J Biol Chem 1999 0.77
93 The relationship between hnRNA+-poly(A) and mRNA+-poly (A) in non-dividing human lymphocytes. Evidence for distinct synthetic pathways for mRNA precursor- and nonprecursor-hnRNA. Biochim Biophys Acta 1978 0.77
94 Multiple RNA splicing and the presence of cryptic RNA splice donor and acceptor sites may contribute to low expression levels and poor immunogenicity of potential DNA vaccines containing the env gene of equine infectious anemia virus (EIAV). Vet Microbiol 2002 0.77
95 Metabolic regulation of protein-bound glutamyl phosphates: insights into the function of prothymosin alpha. J Cell Physiol 1999 0.77
96 Metabolism of polyadenylated mRNA in growing human lymphocytes. Biochim Biophys Acta 1979 0.76
97 Mapping introns by exon excision. Anal Biochem 1989 0.75
98 Determination of the molar concentration of messenger RNA. Methods Enzymol 1987 0.75
99 Prothymosin alpha is not found in yeast. Protein Expr Purif 1998 0.75
100 Analysis of activity and regulation of hGcn5, a human histone acetyltransferase. Methods Enzymol 1999 0.75
101 Nuclease digestion: a method for mapping introns. Methods Enzymol 1989 0.75