Published in Am J Hum Genet on August 01, 1997
Large upward bias in estimation of locus-specific effects from genomewide scans. Am J Hum Genet (2001) 7.53
SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease. Am J Hum Genet (2000) 3.58
Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans. Am J Hum Genet (1999) 2.42
Ranks of genuine associations in whole-genome scans. Genetics (2005) 2.42
A genomewide screen for autism susceptibility loci. Am J Hum Genet (2001) 2.30
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Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15. Am J Hum Genet (1999) 1.74
Scan statistics to scan markers for susceptibility genes. Proc Natl Acad Sci U S A (2000) 1.73
Bayesian association-based fine mapping in small chromosomal segments. Genetics (2004) 1.72
A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22. Proc Natl Acad Sci U S A (2001) 1.64
Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolate. Am J Hum Genet (2002) 1.62
Genomewide scan for prostate cancer-aggressiveness loci. Am J Hum Genet (2000) 1.57
A genome scan in families from Australia and New Zealand confirms the presence of a maternal susceptibility locus for pre-eclampsia, on chromosome 2. Am J Hum Genet (2000) 1.29
Identification of a major locus for age-related cortical cataract on chromosome 6p12-q12 in the Beaver Dam Eye Study. Proc Natl Acad Sci U S A (2004) 1.27
Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium. Proc Natl Acad Sci U S A (2002) 1.23
Genomewide linkage and linkage disequilibrium analyses identify COL6A1, on chromosome 21, as the locus for ossification of the posterior longitudinal ligament of the spine. Am J Hum Genet (2003) 1.15
Nonparametric tests for right-censored data with biased sampling. J R Stat Soc Series B Stat Methodol (2010) 1.07
Mapping of complex traits by single-nucleotide polymorphisms. Am J Hum Genet (1998) 1.05
Assignment of the locus for PLO-SL, a frontal-lobe dementia with bone cysts, to 19q13. Am J Hum Genet (1998) 1.04
Inflated false-positive rates in Hardy-Weinberg and linkage-equilibrium tests are due to sampling on the basis of rare familial phenotypes in finite populations. Am J Hum Genet (2000) 1.02
Maximum Likelihood Estimations and EM Algorithms with Length-biased Data. J Am Stat Assoc (2011) 1.02
Evidence for linkage of adolescent-onset idiopathic generalized epilepsies to chromosome 8-and genetic heterogeneity. Am J Hum Genet (1999) 0.98
Statistical approaches to gene mapping. Am J Hum Genet (2000) 0.96
Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24. Am J Hum Genet (2005) 0.90
HDR: a statistical two-step approach successfully identifies disease genes in autosomal recessive families. J Hum Genet (2016) 0.82
Discriminating between true and false-positive peaks in a genomewide linkage scan, by use of the peak length. Am J Hum Genet (1998) 0.79
Imputation for semiparametric transformation models with biased-sampling data. Lifetime Data Anal (2012) 0.77
Age and sex based genetic locus heterogeneity in type 1 diabetes. J Med Genet (2000) 0.76
Scan statistics in human gene mapping. Am J Hum Genet (2012) 0.75
Recursive partitioning models for linkage in COGA data. BMC Genet (2005) 0.75
Nonparametric and semiparametric regression estimation for length-biased survival data. Lifetime Data Anal (2016) 0.75
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet (1995) 49.77
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Genome screening by searching for shared segments: mapping a gene for benign recurrent intrahepatic cholestasis. Nat Genet (1994) 10.35
Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. Am J Hum Genet (1993) 8.05
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Chromosome-based method for rapid computer simulation in human genetic linkage analysis. Genet Epidemiol (1993) 4.98
Length biased sampling in etiologic studies. Am J Epidemiol (1980) 2.23
Accurate and superaccurate gene mapping. Am J Hum Genet (1985) 1.85
Efficient strategies for genomic searching using the affected-pedigree-member method of linkage analysis. Am J Hum Genet (1994) 1.19
Gametogenesis processes and multilocus gene identity by descent. Am J Hum Genet (1996) 1.15
Use of exact and adjusted liability scores to detect genes affecting common traits. Genet Epidemiol (1995) 0.98
Effect of length sampling bias on labeled mitotic index waves. J Theor Biol (1971) 0.97
Multilocus linkage analysis in humans: detection of linkage and estimation of recombination. Am J Hum Genet (1985) 87.59
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Easy calculations of lod scores and genetic risks on small computers. Am J Hum Genet (1984) 28.51
PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet (1998) 23.25
The VITESSE algorithm for rapid exact multilocus linkage analysis via genotype set-recoding and fuzzy inheritance. Nat Genet (1995) 10.17
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Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3) Nature (1996) 5.32
Computer programs for multilocus haplotyping of general pedigrees. Am J Hum Genet (1995) 4.51
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat Genet (2000) 4.48
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat Genet (1996) 4.09
A primary genetic map of chromosome 13q. Am J Hum Genet (1986) 4.01
Genetic counseling: a consumers' view. N Engl J Med (1972) 3.90
Evaluating pedigree data. I. The estimation of pedigree error in the presence of marker mistyping. Am J Hum Genet (1983) 3.82
Controversy in human genetics: founder effect in Tay-Sachs disease. Am J Hum Genet (1972) 3.72
What participants understand about a maternal serum alpha-fetoprotein screening program. Am J Public Health (1985) 3.67
A genome-wide search for quantitative trait loci underlying asthma. Nature (1996) 3.58
Therapeutic hypothermia after cardiac arrest: an advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation. Circulation (2003) 3.40
Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees. Hum Hered (2001) 3.32
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am J Hum Genet (2001) 3.26
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease. Nat Genet (1999) 3.25
Isolation and mapping of a polymorphic DNA sequence (pTHH22) on chromosome 9 [D9S12]. Nucleic Acids Res (1988) 3.17
The effect of graft function on FK506 plasma levels, dosages, and renal function, with particular reference to the liver. Transplantation (1991) 3.14
Similarity of DNA fingerprints due to chance and relatedness. Hum Hered (1993) 2.90
Localisation of atopy and beta subunit of high-affinity IgE receptor (Fc epsilon RI) on chromosome 11q. Lancet (1993) 2.88
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy maps to chromosome 19q12. Nat Genet (1993) 2.79
A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands. Arch Gen Psychiatry (1982) 2.75
Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE). Hum Mol Genet (2001) 2.75
A primary genetic linkage map for human chromosome 12. Genomics (1987) 2.72
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Fire on an intensive care unit caused by an oxygen cylinder. Anaesthesia (2012) 2.61
Nonparametric simulation-based statistics for detecting linkage in general pedigrees. Am J Hum Genet (1996) 2.57
A radiation hybrid map of the rat genome containing 5,255 markers. Nat Genet (1999) 2.54
Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene. Proc Natl Acad Sci U S A (1994) 2.54
Use of robust variance components models to analyse triglyceride data in families. Ann Hum Genet (1985) 2.52
Efficient computation of lod scores: genotype elimination, genotype redefinition, and hybrid maximum likelihood algorithms. Ann Hum Genet (1989) 2.51
Evaluating pedigree data. II. Identifying the cause of error in families with inconsistencies. Hum Hered (1983) 2.45
A chart review study of late-onset and early-onset schizophrenia. Am J Psychiatry (1989) 2.44
Anticipation in bipolar affective disorder. Am J Hum Genet (1993) 2.44
Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum Mol Genet (1997) 2.43
Does changing the configuration of a motor racing circuit make it safer? Br J Sports Med (2005) 2.40
A quantitative-trait locus on chromosome 6p influences different aspects of developmental dyslexia. Am J Hum Genet (1999) 2.38
Combined linkage and segregation analysis using regressive models. Am J Hum Genet (1988) 2.33
Evidence of linkage disequilibrium between schizophrenia and the SCa1 CAG repeat on chromosome 6p23. Am J Hum Genet (1996) 2.19
Inhibitors of hydroxymethylglutaryl-coenzyme A reductase and risk of fracture among older women. Lancet (2000) 2.17
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The ENCU scoring system. A strategy for solving a class of single-locus genetic counseling problems. Clin Genet (1971) 2.16
Use of a ProSeal laryngeal mask airway for airway maintenance during emergency Caesarean section after failed tracheal intubation. Br J Anaesth (2004) 2.15
Genetic linkage analysis of bipolar affective disorder in an Old Order Amish pedigree. Hum Genet (1992) 2.15
Offering cystic fibrosis carrier screening to an HMO population: factors associated with utilization. Am J Hum Genet (1994) 2.06
Genome-wide association scan for childhood caries implicates novel genes. J Dent Res (2011) 2.05
Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am J Psychiatry (1990) 2.04
A new method to test genetic models in HLA associated diseases: the MASC method. Ann Hum Genet (1988) 2.03
Polygenic control of autoimmune diabetes in nonobese diabetic mice. Nat Genet (1993) 1.98
A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc Natl Acad Sci U S A (1999) 1.96
Emergency airway management in patients with cervical spine injuries. Anaesthesia (1994) 1.88
What are the requirements for medical cover at motor racing circuits? Injury (1999) 1.88
Two-locus models of disease: comparison of likelihood and nonparametric linkage methods. Am J Hum Genet (1993) 1.87
A juvenile-onset, progressive cataract locus on chromosome 3q21-q22 is associated with a missense mutation in the beaded filament structural protein-2. Am J Hum Genet (2000) 1.86
Therapeutic hypothermia after cardiac arrest - implementation in UK intensive care units. Anaesthesia (2010) 1.85
Social language use in parents of autistic individuals. Psychol Med (1992) 1.85
Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci. Am J Hum Genet (2001) 1.82
Psychiatric disorders in the parents of autistic individuals. J Am Acad Child Adolesc Psychiatry (1991) 1.82
Polygenic disease: methods for mapping complex disease traits. Trends Genet (1995) 1.81
Training in basic and advanced life support in UK medical schools: questionnaire survey. BMJ (2001) 1.80
Familial infantile convulsions and paroxysmal choreoathetosis: a new neurological syndrome linked to the pericentromeric region of human chromosome 16. Am J Hum Genet (1997) 1.79
Linkage mapping of dopa-responsive dystonia (DRD) to chromosome 14q. Nat Genet (1993) 1.78
Optimal ascertainment strategies to detect linkage to common disease alleles. Am J Hum Genet (1998) 1.77
The uniqueness of the DSM definition of post-traumatic stress disorder: implications for research. Psychol Med (2002) 1.75
Visual hallucinations in patients with macular degeneration. Am J Psychiatry (1992) 1.75
A gene for Hirschsprung disease (megacolon) in the pericentromeric region of human chromosome 10. Nat Genet (1993) 1.73
X-chromosome markers and manic-depressive illness. Rejection of linkage to Xq28 in nine bipolar pedigrees. Arch Gen Psychiatry (1990) 1.72
Familial cutaneous malignant melanoma: autosomal dominant trait possibly linked to the Rh locus. Proc Natl Acad Sci U S A (1983) 1.72
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Measuring physicians' tolerance for ambiguity and its relationship to their reported practices regarding genetic testing. Med Care (1993) 1.71
Goodness-of-fit tests for locus order in three-point mapping. Genet Epidemiol (1987) 1.71
An evaluation of the Airway Management Device. Anaesthesia (2001) 1.69
The association of affective disorder with Huntington's disease in a case series and in families. Psychol Med (1983) 1.65
Linkage and association between inflammatory bowel disease and a locus on chromosome 12. Am J Hum Genet (1998) 1.64
Endotoxin, reticuloendothelial function, and liver injury. Hepatology (1982) 1.64
Further linkage data on cystic fibrosis: the Utah Study. Am J Hum Genet (1986) 1.63
Statistical testing of genetic linkage under heterogeneity. Biometrics (1993) 1.63
Physicians' knowledge of genetics and genetic tests. Acad Med (1993) 1.62
Close linkage of c-Harvey-ras-1 and the insulin gene to affective disorder is ruled out in three North American pedigrees. Nature (1987) 1.61
Detection of tandem duplications and implications for linkage analysis. Am J Hum Genet (1994) 1.60
The role of endotoxin in liver injury. Gastroenterology (1975) 1.60
Invalidity of the Rao map function for three loci. Hum Hered (1994) 1.59
Volumetric MRI changes in basal ganglia of children with Tourette's syndrome. Neurology (1993) 1.59
Conduct disorder and affective disorder among the offspring of patients with Huntington's disease. Psychol Med (1983) 1.58
Influence of clinical subtype, sex, and lineality on age at onset of major affective disorder in a family sample. Am J Psychiatry (1994) 1.58
Rat gene mapping using PCR-analyzed microsatellites. Genetics (1992) 1.57
Dissecting the loci controlling fetal haemoglobin production on chromosomes 11p and 6q by the regressive approach. Nat Genet (1996) 1.57
Modulation of GTPase activity of G proteins by fluid shear stress and phospholipid composition. Proc Natl Acad Sci U S A (1998) 1.55
Randomized crossover comparison of the proseal with the classic laryngeal mask airway in unparalysed anaesthetized patients. Br J Anaesth (2002) 1.54
Ventricle-brain ratio, computed tomographic density, and brain area in 50 schizophrenics. Arch Gen Psychiatry (1989) 1.54
Ziskind-Somerfeld Research Award 1996. Medial and superior temporal gyral volumes and cerebral asymmetry in schizophrenia versus bipolar disorder. Biol Psychiatry (1997) 1.54
Classification methods for confronting heterogeneity. Adv Genet (2001) 1.53
Determinants of hospital staff nurse turnover. Med Care (1981) 1.52