Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines.

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🔗 View Article (PMID 9323208)

Published in Science on October 10, 1997

Authors

C Boshoff1, Y Endo, P D Collins, Y Takeuchi, J D Reeves, V L Schweickart, M A Siani, T Sasaki, T J Williams, P W Gray, P S Moore, Y Chang, R A Weiss

Author Affiliations

1: Institute of Cancer Research, Chester Beatty Laboratories, London SW3 6JB, UK.

Associated clinical trials:

Effects of Maraviroc (MVC) on HIV-related Kaposi's Sarcoma (KS) | NCT01276236

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science (1994) 39.60

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Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med (1991) 23.89

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell (1986) 22.26

Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med (1995) 21.16

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell (1998) 13.98

Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc Natl Acad Sci U S A (1996) 12.89

A physical map of the human genome. Nature (2001) 12.39

Laser capture microdissection. Science (1996) 12.21

The DNA sequence of human chromosome 21. Nature (2000) 10.66

Dissociation of gp120 from HIV-1 virions induced by soluble CD4. Science (1990) 10.13

Small GTP-binding proteins. Physiol Rev (2001) 9.52

Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and without HIV infection. N Engl J Med (1995) 8.52

Structure and function of lipopolysaccharide binding protein. Science (1990) 7.76

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Kaposi's sarcoma. N Engl J Med (2000) 6.81

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Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia. Proc Natl Acad Sci U S A (2001) 6.70

Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients. Nature (1985) 6.65

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Expression of human immune interferon cDNA in E. coli and monkey cells. Nature (1982) 6.55

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Control of vascular permeability by polymorphonuclear leukocytes in inflammation. Nature (1981) 6.36

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Prostaglandins as potentiators of increased vascular permeability in inflammation. Nature (1973) 6.34

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The mechanism of action of ricin and related toxic lectins on eukaryotic ribosomes. The site and the characteristics of the modification in 28 S ribosomal RNA caused by the toxins. J Biol Chem (1987) 5.79

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Variable and conserved neutralization antigens of human immunodeficiency virus. Nature (1987) 5.29

Cloning and expression of murine immune interferon cDNA. Proc Natl Acad Sci U S A (1983) 5.25

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Role of prostaglandin-mediated vasodilatation in inflammation. Nature (1977) 3.95

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Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI). J Cell Biol (1993) 3.87

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Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha. J Biol Chem (1996) 3.78