Published in Genes Dev on October 01, 1997
Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis. Microbiol Mol Biol Rev (1999) 11.32
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev (2000) 10.64
REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export. RNA (2000) 4.10
Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J (2000) 3.76
Transitions in RNA polymerase II elongation complexes at the 3' ends of genes. EMBO J (2004) 3.50
Protein factors in pre-mRNA 3'-end processing. Cell Mol Life Sci (2008) 3.44
Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export. EMBO J (1998) 3.02
Pre-mRNA processing factors are required for nuclear export. RNA (2000) 2.76
Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes Dev (1998) 2.74
Messenger RNAs are recruited for nuclear export during transcription. Genes Dev (2001) 2.68
Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. Mol Cell Biol (2000) 2.64
Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2000) 2.63
Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation. Mol Cell Biol (1998) 2.61
A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3p. Mol Cell Biol (2000) 2.56
Complex protein interactions within the human polyadenylation machinery identify a novel component. Mol Cell Biol (2000) 2.55
Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation. Mol Cell Biol (1998) 2.26
Control of cleavage site selection during mRNA 3' end formation by a yeast hnRNP. EMBO J (1998) 2.21
Increase in the 64-kDa subunit of the polyadenylation/cleavage stimulatory factor during the G0 to S phase transition. Proc Natl Acad Sci U S A (1998) 2.01
Coupling of termination, 3' processing, and mRNA export. Mol Cell Biol (2002) 1.92
Related eIF3 subunits TIF32 and HCR1 interact with an RNA recognition motif in PRT1 required for eIF3 integrity and ribosome binding. EMBO J (2001) 1.87
A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase II. Genetics (2000) 1.86
Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3'-end formation. Mol Cell Biol (2001) 1.82
Intron status and 3'-end formation control cotranscriptional export of mRNA. Genes Dev (2002) 1.79
Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory roles. RNA (2010) 1.74
Surveillance of nuclear-restricted pre-ribosomes within a subnucleolar region of Saccharomyces cerevisiae. EMBO J (2006) 1.73
An in-depth map of polyadenylation sites in cancer. Nucleic Acids Res (2012) 1.71
Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A (2001) 1.68
Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors. Genes Dev (2004) 1.66
A probabilistic model of 3' end formation in Caenorhabditis elegans. Nucleic Acids Res (2004) 1.60
Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor. Mol Cell Biol (1999) 1.59
Functional specificity of shuttling hnRNPs revealed by genome-wide analysis of their RNA binding profiles. RNA (2005) 1.58
Recognition of polyadenylation sites in yeast pre-mRNAs by cleavage and polyadenylation factor. EMBO J (2001) 1.58
Tailing and 3'-end labeling of RNA with yeast poly(A) polymerase and various nucleotides. RNA (1998) 1.57
A transcriptome-wide atlas of RNP composition reveals diverse classes of mRNAs and lncRNAs. Cell (2013) 1.55
Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3'-end formation. RNA (1999) 1.53
Processivity of the Saccharomyces cerevisiae poly(A) polymerase requires interactions at the carboxyl-terminal RNA binding domain. Mol Cell Biol (1998) 1.51
Specific isoforms of squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis. Genes Dev (1999) 1.50
Global analysis of Pub1p targets reveals a coordinate control of gene expression through modulation of binding and stability. Mol Cell Biol (2005) 1.50
Functional analysis of yeast snoRNA and snRNA 3'-end formation mediated by uncoupling of cleavage and polyadenylation. Mol Cell Biol (2002) 1.49
Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics (2002) 1.40
Evolution of SR protein and hnRNP splicing regulatory factors. Wiley Interdiscip Rev RNA (2011) 1.37
Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2000) 1.35
Distinct roles of two Yth1p domains in 3'-end cleavage and polyadenylation of yeast pre-mRNAs. EMBO J (2000) 1.35
Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor. Nucleic Acids Res (2006) 1.34
Npl3 is an antagonist of mRNA 3' end formation by RNA polymerase II. EMBO J (2005) 1.34
Fip1 regulates the activity of Poly(A) polymerase through multiple interactions. Mol Cell Biol (2001) 1.27
Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution. Mol Cell Biol (2003) 1.27
T7 RNA polymerase-directed transcripts are processed in yeast and link 3' end formation to mRNA nuclear export. RNA (2002) 1.27
Grabbing the message: structural basis of mRNA 3'UTR recognition by Hrp1. EMBO J (2006) 1.26
Synthetic lethal interactions with conditional poly(A) polymerase alleles identify LCP5, a gene involved in 18S rRNA maturation. RNA (1998) 1.25
Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast. Biochim Biophys Acta (2012) 1.24
The role of nuclear cap binding protein Cbc1p of yeast in mRNA termination and degradation. Mol Cell Biol (2000) 1.24
Polyadenylation site choice in yeast is affected by competition between Npl3 and polyadenylation factor CFI. RNA (2007) 1.18
The mRNA encoding the yeast ARE-binding protein Cth2 is generated by a novel 3' processing pathway. Nucleic Acids Res (2008) 1.15
The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formation. Nucleic Acids Res (2003) 1.15
Pti1p and Ref2p found in association with the mRNA 3' end formation complex direct snoRNA maturation. EMBO J (2003) 1.13
Rna14-Rna15 assembly mediates the RNA-binding capability of Saccharomyces cerevisiae cleavage factor IA. Nucleic Acids Res (2004) 1.11
Identification of factors regulating poly(A) tail synthesis and maturation. Mol Cell Biol (2004) 1.11
The export factor Yra1 modulates mRNA 3' end processing. Nat Struct Mol Biol (2011) 1.09
In vivo analysis of nucleolar proteins modified by the yeast arginine methyltransferase Hmt1/Rmt1p. RNA (2003) 1.09
Nuclear export of hnRNP Hrp1p and nuclear export of hnRNP Npl3p are linked and influenced by the methylation state of Npl3p. Mol Cell Biol (2004) 1.08
Evidence for a complex of transcription factor IIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping. J Biol Chem (2011) 1.08
Mpe1, a zinc knuckle protein, is an essential component of yeast cleavage and polyadenylation factor required for the cleavage and polyadenylation of mRNA. Mol Cell Biol (2001) 1.05
A PY-NLS nuclear targeting signal is required for nuclear localization and function of the Saccharomyces cerevisiae mRNA-binding protein Hrp1. J Biol Chem (2008) 1.04
Alternative 3' pre-mRNA processing in Saccharomyces cerevisiae is modulated by Nab4/Hrp1 in vivo. PLoS Biol (2007) 1.04
The essential N terminus of the Pta1 scaffold protein is required for snoRNA transcription termination and Ssu72 function but is dispensable for pre-mRNA 3'-end processing. Mol Cell Biol (2009) 1.02
Analyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation. BMC Genomics (2006) 1.02
Functional dissection of the zinc finger and flanking domains of the Yth1 cleavage/polyadenylation factor. Nucleic Acids Res (2003) 1.01
Assembly of an export-competent mRNP is needed for efficient release of the 3'-end processing complex after polyadenylation. Mol Cell Biol (2009) 1.01
Evidence that poly(A) binding protein has an evolutionarily conserved function in facilitating mRNA biogenesis and export. RNA (2003) 1.01
Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export. Mol Biol Cell (2009) 1.01
Characterization of the ptr6(+) gene in fission yeast: a possible involvement of a transcriptional coactivator TAF in nucleocytoplasmic transport of mRNA. Genetics (1999) 1.00
Novel protein-protein contacts facilitate mRNA 3'-processing signal recognition by Rna15 and Hrp1. J Mol Biol (2010) 1.00
A novel endonuclease activity associated with the Arabidopsis ortholog of the 30-kDa subunit of cleavage and polyadenylation specificity factor. Nucleic Acids Res (2007) 0.99
The spt5 C-terminal region recruits yeast 3' RNA cleavage factor I. Mol Cell Biol (2012) 0.99
An interaction between two RNA binding proteins, Nab2 and Pub1, links mRNA processing/export and mRNA stability. Mol Cell Biol (2007) 0.99
In vivo SELEX reveals novel sequence and structural determinants of Nrd1-Nab3-Sen1-dependent transcription termination. EMBO J (2012) 0.99
UBA1 and UBA2, two proteins that interact with UBP1, a multifunctional effector of pre-mRNA maturation in plants. Mol Cell Biol (2002) 0.99
The Role of Protein Arginine Methylation in mRNP Dynamics. Mol Biol Int (2011) 0.98
Role for Upf2p phosphorylation in Saccharomyces cerevisiae nonsense-mediated mRNA decay. Mol Cell Biol (2006) 0.98
Structural biology of poly(A) site definition. Wiley Interdiscip Rev RNA (2011) 0.94
The Ccr4-Not complex interacts with the mRNA export machinery. PLoS One (2011) 0.93
RBP45 and RBP47, two oligouridylate-specific hnRNP-like proteins interacting with poly(A)+ RNA in nuclei of plant cells. RNA (2000) 0.92
Snu56p is required for Mer1p-activated meiotic splicing. Mol Cell Biol (2008) 0.90
The role of the Brr5/Ysh1 C-terminal domain and its homolog Syc1 in mRNA 3'-end processing in Saccharomyces cerevisiae. RNA (2006) 0.89
The yeast hnRNP-like protein Hrp1/Nab4 sccumulates in the cytoplasm after hyperosmotic stress: a novel Fps1-dependent response. Mol Biol Cell (2003) 0.89
The long and the short of it: the role of the zinc finger polyadenosine RNA binding protein, Nab2, in control of poly(A) tail length. Biochim Biophys Acta (2012) 0.88
The P-loop domain of yeast Clp1 mediates interactions between CF IA and CPF factors in pre-mRNA 3' end formation. PLoS One (2011) 0.87
An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination. Nucleic Acids Res (2011) 0.87
Posttranslational phosphorylation and ubiquitination of the Saccharomyces cerevisiae Poly(A) polymerase at the S/G(2) stage of the cell cycle. Mol Cell Biol (2000) 0.87
The AMT1 arginine methyltransferase gene is important for plant infection and normal hyphal growth in Fusarium graminearum. PLoS One (2012) 0.86
A unified model for yeast transcript definition. Genome Res (2013) 0.84
In silico analysis of 3'-end-processing signals in Aspergillus oryzae using expressed sequence tags and genomic sequencing data. DNA Res (2011) 0.83
Selection of yeast strains with enhanced expression of Plasmodium falciparum proteins. Mol Biochem Parasitol (2008) 0.83
mRNA 3' end processing factors: a phylogenetic comparison. Comp Funct Genomics (2012) 0.82
Cryptic transcription and early termination in the control of gene expression. Genet Res Int (2011) 0.82
Coupled RNA polymerase II transcription and 3' end formation with yeast whole-cell extracts. RNA (2010) 0.81
Identification of Protein Arginine Methyltransferase 5 as a Regulator for Encystation of Acanthamoeba. Korean J Parasitol (2016) 0.80
Post-transcriptional regulation of iron homeostasis in Saccharomyces cerevisiae. Int J Mol Sci (2013) 0.80
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Basic local alignment search tool. J Mol Biol (1990) 659.07
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol Gen Genet (1984) 35.54
Replacement of chromosome segments with altered DNA sequences constructed in vitro. Proc Natl Acad Sci U S A (1979) 17.55
Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure. Yeast (1995) 13.20
Starting at the beginning, middle, and end: translation initiation in eukaryotes. Cell (1997) 7.15
Degradation of mRNA in eukaryotes. Cell (1995) 6.81
Preparation of high molecular weight RNA. Methods Enzymol (1991) 5.60
Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1. Mol Cell Biol (1993) 5.24
The two-hybrid system: an assay for protein-protein interactions. Trends Genet (1994) 5.06
A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes Dev (1996) 3.78
Synthetic enhancement in gene interaction: a genetic tool come of age. Trends Genet (1993) 3.75
Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins. Science (1996) 3.70
A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution. EMBO J (1994) 3.65
Primary structures of the heterogeneous nuclear ribonucleoprotein A2, B1, and C2 proteins: a diversity of RNA binding proteins is generated by small peptide inserts. Proc Natl Acad Sci U S A (1989) 3.51
Sequence similarity between the 73-kilodalton protein of mammalian CPSF and a subunit of yeast polyadenylation factor I. Science (1996) 3.29
Copper staining: a five-minute protein stain for sodium dodecyl sulfate-polyacrylamide gels. Anal Biochem (1987) 3.28
Role of polyadenylation in nucleocytoplasmic transport of mRNA. Mol Cell Biol (1996) 3.26
Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast. Cell (1992) 3.20
Mature mRNA 3' end formation stimulates RNA export from the nucleus. EMBO J (1991) 3.09
The end of the message--another link between yeast and mammals. Science (1996) 2.96
Dependence of yeast pre-mRNA 3'-end processing on CFT1: a sequence homolog of the mammalian AAUAAA binding factor. Science (1996) 2.81
A yeast RNA-binding protein shuttles between the nucleus and the cytoplasm. Mol Cell Biol (1994) 2.66
RNA processing generates the mature 3' end of yeast CYC1 messenger RNA in vitro. Science (1988) 2.62
The biochemistry of polyadenylation. Trends Biochem Sci (1996) 2.55
Nuclear export of proteins and RNAs. Curr Opin Cell Biol (1997) 2.51
3'-end-forming signals of yeast mRNA. Trends Biochem Sci (1996) 2.47
The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins. Genes Dev (1997) 2.46
Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. J Cell Biol (1994) 2.37
Mutations in the yeast RNA14 and RNA15 genes result in an abnormal mRNA decay rate; sequence analysis reveals an RNA-binding domain in the RNA15 protein. Mol Cell Biol (1991) 2.35
Separation of factors required for cleavage and polyadenylation of yeast pre-mRNA. Mol Cell Biol (1992) 2.34
A mutant nuclear protein with similarity to RNA binding proteins interferes with nuclear import in yeast. Mol Biol Cell (1992) 2.33
The major yeast poly(A)-binding protein is associated with cleavage factor IA and functions in premessenger RNA 3'-end formation. Proc Natl Acad Sci U S A (1997) 2.26
Yeast Pab1 interacts with Rna15 and participates in the control of the poly(A) tail length in vitro. Mol Cell Biol (1997) 2.18
The FIP1 gene encodes a component of a yeast pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase. Cell (1995) 2.06
A polyadenylation factor subunit is the human homologue of the Drosophila suppressor of forked protein. Nature (1994) 2.03
Biochemistry and regulation of pre-mRNA splicing. Curr Opin Cell Biol (1996) 1.98
Isolation of an active gene encoding human hnRNP protein A1. Evidence for alternative splicing. J Mol Biol (1989) 1.95
Purification of the Saccharomyces cerevisiae cleavage/polyadenylation factor I. Separation into two components that are required for both cleavage and polyadenylation of mRNA 3' ends. J Biol Chem (1996) 1.90
NOP3 is an essential yeast protein which is required for pre-rRNA processing. J Cell Biol (1992) 1.89
Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors. J Biol Chem (1996) 1.88
PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I. Mol Cell Biol (1997) 1.88
Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymerase. Mol Cell Biol (1992) 1.84
Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit. Mol Cell Biol (1994) 1.83
Essential yeast protein with unexpected similarity to subunits of mammalian cleavage and polyadenylation specificity factor (CPSF). Science (1996) 1.79
Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3. Genetics (1996) 1.76
Reconstitution of nuclear protein transport with semi-intact yeast cells. J Cell Biol (1993) 1.73
The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism. Bioessays (1996) 1.63
Termination and pausing of RNA polymerase II downstream of yeast polyadenylation sites. Mol Cell Biol (1993) 1.43
The influence of 5' and 3' end structures on pre-mRNA metabolism. J Cell Sci Suppl (1995) 1.32
Structure-function relationships in the Saccharomyces cerevisiae poly(A) polymerase. Identification of a novel RNA binding site and a domain that interacts with specificity factor(s). J Biol Chem (1995) 1.29
Cellular localization of RNA14p and RNA15p, two yeast proteins involved in mRNA stability. J Cell Sci (1994) 1.15
Silver staining of native and denatured eucaryotic DNA in agarose gels. Anal Biochem (1987) 1.12
Monoclonal antibodies to yeast poly(A) polymerase (PAP) provide evidence for association of PAP with cleavage factor I. Biochemistry (1995) 1.05
Differential accumulation of mRNA and interspersed RNA during Xenopus oogenesis and embryogenesis. Zygote (1994) 0.87
Purification and cloning of amyloid precursor protein beta-secretase from human brain. Nature (1999) 5.77
Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell (1985) 5.27
Cyanide-insensitive respiration. An alternative mitochondrial pathway. Subcell Biochem (1975) 5.02
Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. Proc Natl Acad Sci U S A (1984) 4.90
Cosmid vectors for rapid genomic walking, restriction mapping, and gene transfer. Proc Natl Acad Sci U S A (1987) 4.13
Biomarker identification by feature wrappers. Genome Res (2001) 3.93
Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. EMBO J (1998) 3.87
Inherited microdeletions in the Angelman and Prader-Willi syndromes define an imprinting centre on human chromosome 15. Nat Genet (1995) 3.79
A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export. Genes Dev (1996) 3.78
Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae. J Cell Biol (2000) 3.73
Site-specific polyadenylation in a cell-free reaction. Cell (1984) 3.59
G-protein signaling through tubby proteins. Science (2001) 3.59
Specific inhibition of mitochondrial Ca++ transport by ruthenium red. Biochem Biophys Res Commun (1971) 3.53
Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol Cell (1999) 3.46
The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility. Mol Cell (2000) 3.36
Refractive Error Study in Children: sampling and measurement methods for a multi-country survey. Am J Ophthalmol (2000) 3.22
The IC-SNURF-SNRPN transcript serves as a host for multiple small nucleolar RNA species and as an antisense RNA for UBE3A. Hum Mol Genet (2001) 3.07
Peroxisomal and mitochondrial defects in the cerebro-hepato-renal syndrome. Science (1973) 2.91
Transition-state analogue inhibitors of gamma-secretase bind directly to presenilin-1. Nat Cell Biol (2000) 2.84
HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection. Genes Dev (1998) 2.82
Mammography and clinical examination in mass screening for cancer of the breast. Cancer (1967) 2.80
Pre-mRNA processing factors are required for nuclear export. RNA (2000) 2.76
Arginine methylation facilitates the nuclear export of hnRNP proteins. Genes Dev (1998) 2.74
Messenger RNAs are recruited for nuclear export during transcription. Genes Dev (2001) 2.68
State of the arg: protein methylation at arginine comes of age. Cell (2001) 2.68
A yeast RNA-binding protein shuttles between the nucleus and the cytoplasm. Mol Cell Biol (1994) 2.66
Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. Mol Cell Biol (2000) 2.64
Comparison of the effects of e-cigarette vapor and cigarette smoke on indoor air quality. Inhal Toxicol (2012) 2.63
Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins. Genes Dev (1999) 2.56
Nucleocytoplasmic transport of macromolecules. Microbiol Mol Biol Rev (1997) 2.51
Kinetics of spindle pole body separation in budding yeast. Proc Natl Acad Sci U S A (1995) 2.51
The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay. Mol Cell (2000) 2.50
The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm. Proc Natl Acad Sci U S A (1995) 2.48
Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import. J Cell Biol (1995) 2.43
DSPP mutation in dentinogenesis imperfecta Shields type II. Nat Genet (2001) 2.39
Use of time-lapse microscopy to visualize rapid movement of the replication origin region of the chromosome during the cell cycle in Bacillus subtilis. Mol Microbiol (1998) 2.36
Prospective multicenter evaluation of the pulmonary embolism rule-out criteria. J Thromb Haemost (2008) 2.33
The yeast nuclear import receptor is required for mitosis. Proc Natl Acad Sci U S A (1995) 2.23
Dynamic localization of the nuclear import receptor and its interactions with transport factors. J Cell Biol (1996) 2.22
Slk19p is a centromere protein that functions to stabilize mitotic spindles. J Cell Biol (1999) 2.21
Seven novel methylation guide small nucleolar RNAs are processed from a common polycistronic transcript by Rat1p and RNase III in yeast. Mol Cell Biol (1999) 2.20
TLR signaling by tumor and immune cells: a double-edged sword. Oncogene (2008) 2.18
Cardiac troponin I phosphorylation increases the rate of cardiac muscle relaxation. Circ Res (1995) 2.09
Feature (gene) selection in gene expression-based tumor classification. Mol Genet Metab (2001) 2.08
DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication. Genes Dev (1997) 2.06
The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol Biol Cell (1998) 2.02
Elevated serum and synovial fluid TNF-like ligand 1A (TL1A) is associated with autoantibody production in patients with rheumatoid arthritis. Scand J Rheumatol (2013) 2.02
Factors affecting nuclear export of the 60S ribosomal subunit in vivo. Mol Biol Cell (2000) 2.00
Mutants in a yeast Ran binding protein are defective in nuclear transport. EMBO J (1995) 1.97
A novel methyltransferase (Hmt1p) modifies poly(A)+-RNA-binding proteins. Mol Cell Biol (1996) 1.95
A GTPase controlling nuclear trafficking: running the right way or walking RANdomly? Cell (1996) 1.95
A 3,000-year record of penguin populations. Nature (2000) 1.94
Purification of the Saccharomyces cerevisiae cleavage/polyadenylation factor I. Separation into two components that are required for both cleavage and polyadenylation of mRNA 3' ends. J Biol Chem (1996) 1.90
Importin/karyopherin protein family members required for mRNA export from the nucleus. Proc Natl Acad Sci U S A (1997) 1.87
Sporadic imprinting defects in Prader-Willi syndrome and Angelman syndrome: implications for imprint-switch models, genetic counseling, and prenatal diagnosis. Am J Hum Genet (1998) 1.87
Electrophoretic separation of polyadenylation-specific complexes. Genes Dev (1987) 1.86
Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase. Mol Cell Biol (1999) 1.83
Evidence that HetR protein is an unusual serine-type protease. Proc Natl Acad Sci U S A (1998) 1.83
Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3'-end formation. Mol Cell Biol (2001) 1.82
Family-based linkage disequilibrium mapping using SNP marker haplotypes: application to a potential locus for schizophrenia at chromosome 22q11. Mol Psychiatry (2000) 1.81
Monitoring expression of HER-2 on circulating epithelial cells in patients with advanced breast cancer. Int J Oncol (2002) 1.81
Analysis of RNA cleavage at the adenovirus-2 L3 polyadenylation site. EMBO J (1986) 1.80
Genotypic and phenotypic spectrum in tricho-rhino-phalangeal syndrome types I and III. Am J Hum Genet (2000) 1.80
Molecular cloning of human plasma membrane phospholipid scramblase. A protein mediating transbilayer movement of plasma membrane phospholipids. J Biol Chem (1997) 1.80
Highways for protein delivery to the mitochondria. Trends Biochem Sci (1997) 1.79
Protein-DNA interactions at a dioxin-responsive enhancer. Analysis of six bona fide DNA-binding sites for the liganded Ah receptor. J Biol Chem (1993) 1.79
Nuf2, a spindle pole body-associated protein required for nuclear division in yeast. J Cell Biol (1994) 1.77
Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3. Genetics (1996) 1.76
An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Proc Natl Acad Sci U S A (1998) 1.76
Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis. Oncogene (2009) 1.76
Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. Curr Biol (1999) 1.75
[German S3-guideline "Diagnosis and treatment of esophagogastric cancer"]. Z Gastroenterol (2011) 1.74
Reconstitution of nuclear protein transport with semi-intact yeast cells. J Cell Biol (1993) 1.73
KLF8 transcription factor participates in oncogenic transformation. Oncogene (2006) 1.71
Structure of yeast poly(A) polymerase alone and in complex with 3'-dATP. Science (2000) 1.70
Inhibition of homologous complement by CD59 is mediated by a species-selective recognition conferred through binding to C8 within C5b-8 or C9 within C5b-9. J Immunol (1991) 1.70
High prevalence of bla(CTX-M) extended-spectrum β-lactamase genes in Escherichia coli isolates from pets and emergence of CTX-M-64 in China. Clin Microbiol Infect (2010) 1.70
Point mutations upstream of the yeast ADH2 poly(A) site significantly reduce the efficiency of 3'-end formation. Mol Cell Biol (1991) 1.69
The structure and oligomerization of the yeast arginine methyltransferase, Hmt1. Nat Struct Biol (2000) 1.69
Implementing the quantum von Neumann architecture with superconducting circuits. Science (2011) 1.68
Peptidomimetic probes and molecular modeling suggest that Alzheimer's gamma-secretase is an intramembrane-cleaving aspartyl protease. Biochemistry (1999) 1.67
Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export. Genes Dev (1999) 1.67
beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4. J Biol Chem (2000) 1.67
The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol Biol Cell (2001) 1.66
KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9. Oncogene (2010) 1.65
Nucleologenesis: composition and fate of prenucleolar bodies. Chromosoma (1985) 1.63
A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s. J Cell Biol (1995) 1.63
A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast. Nature (1991) 1.61
5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States. J Allergy Clin Immunol (2000) 1.60
Efficient silicon light-emitting diodes. Nature (2001) 1.60
The effects of melatonin therapy on the development of scoliosis after pinealectomy in the chicken. J Bone Joint Surg Am (1999) 1.58
Objective Assessment of Multiresolution Image Fusion Algorithms for Context Enhancement in Night Vision: A Comparative Study. IEEE Trans Pattern Anal Mach Intell (2011) 1.57
Extragenic suppressors of mutations in the cytoplasmic C terminus of SEC63 define five genes in Saccharomyces cerevisiae. Genetics (1993) 1.57
Mapping interactions between nuclear transport factors in living cells reveals pathways through the nuclear pore complex. Mol Cell (2000) 1.55
Functional calcium release channel formed by the carboxyl-terminal portion of ryanodine receptor. Biophys J (1997) 1.55