Published in Genomics on November 01, 1997
The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors. Br J Pharmacol (2013) 5.74
Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implications. Steroids (2007) 2.56
The G-protein-coupled estrogen receptor GPER in health and disease. Nat Rev Endocrinol (2011) 2.33
Involvement of G protein-coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons. Mol Endocrinol (2009) 1.72
GPR30: A G protein-coupled receptor for estrogen. Mol Cell Endocrinol (2007) 1.59
Mechanisms of estrogen signaling and gene expression via GPR30. Mol Cell Endocrinol (2009) 1.55
Mechanisms of resistance to endocrine therapy in breast cancer: focus on signaling pathways, miRNAs and genetically based resistance. Int J Mol Sci (2012) 1.44
Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology. Endocrinology (2012) 1.43
Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation. Cancer Res (2009) 1.39
The ins and outs of GPR30: a transmembrane estrogen receptor. J Steroid Biochem Mol Biol (2008) 1.36
A novel estrogen receptor GPER inhibits mitochondria permeability transition pore opening and protects the heart against ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol (2009) 1.33
Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis. J Neuroimmunol (2009) 1.32
Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors. J Biol Chem (2008) 1.32
Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues. J Endocrinol (2009) 1.27
Mechanisms of gender-linked ischemic brain injury. Restor Neurol Neurosci (2009) 1.24
The G protein-coupled receptor GPR30 inhibits human urothelial cell proliferation. Endocrinology (2008) 1.23
Estrogen biology: new insights into GPER function and clinical opportunities. Mol Cell Endocrinol (2014) 1.23
Membrane estradiol signaling in the brain. Front Neuroendocrinol (2009) 1.22
Estrogen signaling characteristics of Atlantic croaker G protein-coupled receptor 30 (GPR30) and evidence it is involved in maintenance of oocyte meiotic arrest. Endocrinology (2008) 1.18
Neuroprotective actions of brain aromatase. Front Neuroendocrinol (2009) 1.14
New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation. Biochim Biophys Acta (2009) 1.13
Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer. BMC Cancer (2012) 1.09
Differential screening and suppression subtractive hybridization identified genes differentially expressed in an estrogen receptor-positive breast carcinoma cell line. Nucleic Acids Res (1998) 1.09
Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER. Prostaglandins Other Lipid Mediat (2009) 1.07
A novel genetic locus for low renin hypertension: familial hyperaldosteronism type II maps to chromosome 7 (7p22). J Med Genet (2000) 1.07
The G protein-coupled receptor 87 is necessary for p53-dependent cell survival in response to genotoxic stress. Cancer Res (2009) 1.05
Estrogen regulates estrogen receptors and antioxidant gene expression in mouse skeletal muscle. PLoS One (2010) 1.05
Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30. Mol Endocrinol (2009) 1.05
Spinal synthesis of estrogen and concomitant signaling by membrane estrogen receptors regulate spinal κ- and μ-opioid receptor heterodimerization and female-specific spinal morphine antinociception. J Neurosci (2011) 1.04
G-protein coupled receptor 30 (GPR30): a novel regulator of endothelial inflammation. PLoS One (2012) 1.03
Rapid pain modulation with nuclear receptor ligands. Brain Res Rev (2008) 1.03
Estrogen induces rapid translocation of estrogen receptor beta, but not estrogen receptor alpha, to the neuronal plasma membrane. Neuroscience (2008) 1.03
Derailed estrogen signaling and breast cancer: an authentic couple. Endocr Rev (2012) 1.01
Post-synaptic density-95 (PSD-95) binding capacity of G-protein-coupled receptor 30 (GPR30), an estrogen receptor that can be identified in hippocampal dendritic spines. J Biol Chem (2013) 1.01
Rapid action of oestrogen in luteinising hormone-releasing hormone neurones: the role of GPR30. J Neuroendocrinol (2009) 1.01
Transit of hormonal and EGF receptor-dependent signals through cholesterol-rich membranes. Steroids (2006) 1.00
Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice. Endocrinology (2012) 0.98
GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes. J Biol Chem (2012) 0.96
Loss of GPER identifies new targets for therapy among a subgroup of ERα-positive endometrial cancer patients with poor outcome. Br J Cancer (2012) 0.96
Conserved estrogen binding and signaling functions of the G protein-coupled estrogen receptor 1 (GPER) in mammals and fish. Steroids (2010) 0.96
GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice. J Bone Miner Res (2011) 0.95
Membrane-initiated estradiol signaling regulating sexual receptivity. Front Endocrinol (Lausanne) (2011) 0.94
The putative G-protein coupled estrogen receptor agonist G-1 suppresses proliferation of ovarian and breast cancer cells in a GPER-independent manner. Am J Transl Res (2012) 0.94
Role of estrogen in diastolic dysfunction. Am J Physiol Heart Circ Physiol (2014) 0.93
G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection. J Mol Endocrinol (2013) 0.92
G protein-coupled oestrogen receptor 1 (GPER1)/GPR30: a new player in cardiovascular and metabolic oestrogenic signalling. Br J Pharmacol (2011) 0.92
Comparison of the effects of estradiol and progesterone on serotonergic function. Biol Psychiatry (2012) 0.92
Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis. Horm Behav (2014) 0.91
Estrogen regulates Hippo signaling via GPER in breast cancer. J Clin Invest (2015) 0.91
YAP regulates cell proliferation, migration, and steroidogenesis in adult granulosa cell tumors. Endocr Relat Cancer (2014) 0.90
Estrogens in the wrong place at the wrong time: Fetal BPA exposure and mammary cancer. Reprod Toxicol (2014) 0.90
GPER Function in Breast Cancer: An Overview. Front Endocrinol (Lausanne) (2014) 0.90
Estrogen regulates epithelial cell deformability by modulation of cortical actomyosin through phosphorylation of nonmuscle myosin heavy-chain II-B filaments. Endocrinology (2006) 0.90
Alternate estrogen receptors promote invasion of inflammatory breast cancer cells via non-genomic signaling. PLoS One (2012) 0.90
Interplay of estrogen receptors and FOXA factors in the liver cancer. Mol Cell Endocrinol (2015) 0.90
G protein-coupled estrogen receptor (GPER) expression in normal and abnormal endometrium. Reprod Sci (2012) 0.90
Unraveling the mechanisms underlying the rapid vascular effects of steroids: sorting out the receptors and the pathways. Br J Pharmacol (2011) 0.89
Gender influences the response to experimental silica-induced lung fibrosis in mice. Am J Physiol Lung Cell Mol Physiol (2010) 0.89
cAMP response element-binding protein (CREB) and nuclear factor κB mediate the tamoxifen-induced up-regulation of glutamate transporter 1 (GLT-1) in rat astrocytes. J Biol Chem (2013) 0.88
Activation of ERα signaling differentially modulates IFN-γ induced HLA-class II expression in breast cancer cells. PLoS One (2014) 0.87
Importance of sex to pain and its amelioration; relevance of spinal estrogens and its membrane receptors. Front Neuroendocrinol (2012) 0.87
International Union of Basic and Clinical Pharmacology. XCVII. G Protein-Coupled Estrogen Receptor and Its Pharmacologic Modulators. Pharmacol Rev (2015) 0.87
Membrane-initiated estradiol actions mediate structural plasticity and reproduction. Front Neuroendocrinol (2012) 0.87
ER and PR signaling nodes during mammary gland development. Breast Cancer Res (2012) 0.86
Rapid signaling mechanisms of estrogens in the developing cerebellum. Brain Res Rev (2007) 0.85
GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts. Endocr Relat Cancer (2014) 0.85
The Cell Surface Estrogen Receptor, G Protein- Coupled Receptor 30 (GPR30), is Markedly Down Regulated During Breast Tumorigenesis. Breast Cancer (Auckl) (2008) 0.84
G Protein-Coupled Receptor 87: a Promising Opportunity for Cancer Drug Discovery. Mol Cell Pharmacol (2010) 0.84
Estrogen receptors in the central nervous system and their implication for dopamine-dependent cognition in females. Horm Behav (2015) 0.84
Stimulation of GPR30 increases release of EMMPRIN-containing microvesicles in human uterine epithelial cells. J Clin Endocrinol Metab (2012) 0.83
Evidence that the G protein-coupled membrane receptor GPR30 contributes to the cardiovascular actions of estrogen. Gend Med (2011) 0.83
G protein-coupled receptors: extranuclear mediators for the non-genomic actions of steroids. Int J Mol Sci (2014) 0.82
What does an orphan G-protein-coupled receptor have to do with estrogen? Breast Cancer Res (2005) 0.81
Induction of G protein-coupled estrogen receptor (GPER) and nuclear steroid hormone receptors by gonadotropins in human granulosa cells. Histochem Cell Biol (2011) 0.81
Cellular targets of estrogen signaling in regeneration of inner ear sensory epithelia. Hear Res (2009) 0.81
Exogenous hormonal regulation in breast cancer cells by phytoestrogens and endocrine disruptors. Curr Med Chem (2014) 0.81
Contributions of academic laboratories to the discovery and development of chemical biology tools. J Med Chem (2013) 0.81
The therapeutic target of estrogen receptor-alpha36 in estrogen-dependent tumors. J Transl Med (2014) 0.80
Expression of G protein-coupled estrogen receptor in irritable bowel syndrome and its clinical significance. Int J Clin Exp Pathol (2014) 0.79
Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1. Cancer Res (2016) 0.79
GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro. Sci Rep (2016) 0.79
Biosensor-based approach identifies four distinct calmodulin-binding domains in the G protein-coupled estrogen receptor 1. PLoS One (2014) 0.79
Estrogen modulation of MgATPase activity of nonmuscle myosin-II-B filaments. Endocrinology (2006) 0.79
G protein-coupled estrogen receptor in energy homeostasis and obesity pathogenesis. Prog Mol Biol Transl Sci (2013) 0.79
Estradiol Membrane-Initiated Signaling and Female Reproduction. Compr Physiol (2015) 0.78
GPER-novel membrane oestrogen receptor. Clin Sci (Lond) (2016) 0.78
A common hypofunctional genetic variant of GPER is associated with increased blood pressure in women. Br J Clin Pharmacol (2014) 0.77
Estrogen induces two distinct cholesterol crystallization pathways by activating ERα and GPR30 in female mice. J Lipid Res (2015) 0.77
Differences in GPR30 Regulation by Chlorotriazine Herbicides in Human Breast Cells. Biochem Res Int (2016) 0.77
GPR30 FORMS AN INTEGRAL PART OF E2-PROTECTIVE PATHWAY IN EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS. Immunol Endocr Metab Agents Med Chem (2011) 0.77
Pregnancy Augments G Protein Estrogen Receptor (GPER) Induced Vasodilation in Rat Uterine Arteries via the Nitric Oxide - cGMP Signaling Pathway. PLoS One (2015) 0.77
Inhibition of GPR30 by estriol prevents growth stimulation of triple-negative breast cancer cells by 17β-estradiol. BMC Cancer (2014) 0.77
Estrogens Suppress Spinal Endomorphin 2 Release in Female Rats in Phase with the Estrous Cycle. Neuroendocrinology (2015) 0.76
Osteoprotective effect of combination therapy of low-dose oestradiol with G15, a specific antagonist of GPR30/GPER in ovariectomy-induced osteoporotic rats. Biosci Rep (2015) 0.76
G-protein-coupled estrogen receptor as a new therapeutic target for treating coronary artery disease. World J Cardiol (2014) 0.76
Activation of novel estrogen receptor GPER results in inhibition of cardiocyte apoptosis and cardioprotection. Mol Med Rep (2015) 0.76
Estradiol modulates myosin regulatory light chain phosphorylation and contractility in skeletal muscle of female mice. Am J Physiol Endocrinol Metab (2016) 0.76
Acting on Hormone Receptors with Minimal Side Effect on Cell Proliferation: A Timely Challenge Illustrated with GLP-1R and GPER. Front Endocrinol (Lausanne) (2013) 0.76
The Arcuate Estrogen-Regulated Transcriptome: Estrogen Response Element-Dependent and -Independent Signaling of ERα in Female Mice. Endocrinology (2017) 0.75
G Protein-Coupled Estrogen Receptor (GPER) Agonist Dual Binding Mode Analyses toward Understanding of its Activation Mechanism: A Comparative Homology Modeling Approach. Mol Inform (2013) 0.75
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