Published in Endocrinology on December 04, 2012
Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice. J Clin Invest (2014) 1.05
The role of hypothalamic estrogen receptors in metabolic regulation. Front Neuroendocrinol (2014) 0.93
Steroid receptor coactivators: servants and masters for control of systems metabolism. Trends Endocrinol Metab (2014) 0.90
Estrogens prevent metabolic dysfunctions induced by circadian disruptions in female mice. Endocrinology (2015) 0.84
Estrogen response element-independent signaling partially restores post-ovariectomy body weight gain but is not sufficient for 17β-estradiol's control of energy homeostasis. Steroids (2013) 0.83
Major epigenetic development distinguishing neuronal and non-neuronal cells occurs postnatally in the murine hypothalamus. Hum Mol Genet (2013) 0.82
Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences. Mol Endocrinol (2013) 0.82
The ERα-PI3K Cascade in Proopiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice. Endocrinology (2015) 0.81
Nuclear receptor coactivators: regulators of steroid action in brain and behaviour. J Neuroendocrinol (2013) 0.80
Progress in the molecular understanding of central regulation of body weight by estrogens. Obesity (Silver Spring) (2015) 0.80
PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice. Sci Rep (2016) 0.78
Apolipoprotein A-IV Inhibits AgRP/NPY Neurons and Activates Pro-Opiomelanocortin Neurons in the Arcuate Nucleus. Neuroendocrinology (2015) 0.78
Minireview: nuclear receptor coregulators of the p160 family: insights into inflammation and metabolism. Mol Endocrinol (2015) 0.77
Estradiol Preferentially Induces Progestin Receptor-A (PR-A) Over PR-B in Cells Expressing Nuclear Receptor Coactivators in the Female Mouse Hypothalamus(1,2,3). eNeuro (2015) 0.76
Estrogen Receptor-α in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females. Hypertension (2016) 0.76
Targeting steroid receptor coactivator 1 with antisense oligonucleotides increases insulin-stimulated skeletal muscle glucose uptake in chow-fed and high-fat-fed male rats. Am J Physiol Endocrinol Metab (2014) 0.75
Regulation of Estrogen Receptor α Expression in the Hypothalamus by Sex Steroids: Implication in the Regulation of Energy Homeostasis. Int J Endocrinol (2015) 0.75
SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice. PLoS One (2016) 0.75
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci (2009) 21.94
A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature (1997) 11.15
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature (2001) 8.95
Increased adipose tissue in male and female estrogen receptor-alpha knockout mice. Proc Natl Acad Sci U S A (2000) 5.47
Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron (2006) 5.27
STAT3 signalling is required for leptin regulation of energy balance but not reproduction. Nature (2003) 5.27
SRC-1 and TIF2 control energy balance between white and brown adipose tissues. Cell (2002) 4.31
Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science (1998) 3.85
Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nat Med (2011) 2.74
Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat Med (2006) 2.72
Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metab (2011) 2.61
Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome. Proc Natl Acad Sci U S A (2007) 2.59
A role for central nervous system PPAR-γ in the regulation of energy balance. Nat Med (2011) 2.34
Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat. Nat Neurosci (2001) 2.32
Modulation of appetite by gonadal steroid hormones. Philos Trans R Soc Lond B Biol Sci (2006) 2.30
Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer. Genomics (1997) 2.28
Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity. Circ Res (2009) 2.16
Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology (2009) 2.10
Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice. Endocrinology (2008) 2.09
An estrogen receptor (ER)alpha deoxyribonucleic acid-binding domain knock-in mutation provides evidence for nonclassical ER pathway signaling in vivo. Mol Endocrinol (2002) 2.08
Obesity and disturbed lipoprotein profile in estrogen receptor-alpha-deficient male mice. Biochem Biophys Res Commun (2000) 1.94
Cyclic estradiol treatment normalizes body weight and restores physiological patterns of spontaneous feeding and sexual receptivity in ovariectomized rats. Horm Behav (2002) 1.91
Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice. J Clin Invest (2011) 1.81
GPR30 does not mediate estrogenic responses in reproductive organs in mice. Biol Reprod (2008) 1.67
Cross-talk between estrogen and leptin signaling in the hypothalamus. Am J Physiol Endocrinol Metab (2008) 1.67
Deficits in E2-dependent control of feeding, weight gain, and cholecystokinin satiation in ER-alpha null mice. Endocrinology (2001) 1.61
PI3K signaling in the ventromedial hypothalamic nucleus is required for normal energy homeostasis. Cell Metab (2010) 1.57
Non-genomic actions of estrogens and their interaction with genomic actions in the brain. Front Neuroendocrinol (2007) 1.56
Discovery of three novel G-protein-coupled receptor genes. Genomics (1998) 1.50
Developmental phenotype of a membrane only estrogen receptor alpha (MOER) mouse. J Biol Chem (2008) 1.44
Acute activation of ER alpha decreases food intake, meal size, and body weight in ovariectomized rats. Am J Physiol Regul Integr Comp Physiol (2007) 1.35
Expression pattern of G protein-coupled receptor 30 in LacZ reporter mice. Endocrinology (2008) 1.35
Ovarian influences on the meal patterns of female rats. Physiol Behav (1976) 1.33
Molecular mechanisms and cellular biology of the steroid receptor coactivator (SRC) family in steroid receptor function. Rev Endocr Metab Disord (2002) 1.28
The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized mice. Am J Physiol Endocrinol Metab (2008) 1.22
Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a. J Biol Chem (2001) 1.20
Estradiol enhances cholecystokinin-dependent lipid-induced satiation and activates estrogen receptor-alpha-expressing cells in the nucleus tractus solitarius of ovariectomized rats. Endocrinology (2007) 1.20
PI3K signaling effects in hypothalamic neurons mediated by estrogen. J Comp Neurol (2008) 1.19
Differential expression and regional distribution of steroid receptor coactivators SRC-1 and SRC-2 in brain and pituitary. Endocrinology (2000) 1.15
Association of the estrogen receptor-alpha gene with the metabolic syndrome and its component traits in African-American families: the Insulin Resistance Atherosclerosis Family Study. Diabetes (2007) 1.10
Divergent effects of estradiol and the estrogen receptor-alpha agonist PPT on eating and activation of PVN CRH neurons in ovariectomized rats and mice. Brain Res (2009) 1.03
Estradiol acts in the medial preoptic area, arcuate nucleus, and dorsal raphe nucleus to reduce food intake in ovariectomized rats. Horm Behav (2011) 1.03
Hormone replacement therapy and stroke. Curr Vasc Pharmacol (2008) 0.99
Expression of CD133, PAX2, ESA, and GPR30 in invasive ductal breast carcinomas. Chin Med J (Engl) (2009) 0.98
Sex hormones and the selective estrogen receptor modulator tamoxifen modulate weekly body weights and food intakes in adolescent and adult rats. J Nutr (2001) 0.96
Steroid receptor coactivator-1 from brain physically interacts differentially with steroid receptor subtypes. Endocrinology (2008) 0.87
Sexual behaviour and sexual motivation in the female rat. Nature (1973) 0.85
Differential effects of YM440 a hypoglycemic agent on binding to a peroxisome proliferator-activated receptor gamma and its transactivation. Biochem Pharmacol (2003) 0.77
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol (2008) 23.93
The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19
Combinatorial control of gene expression by nuclear receptors and coregulators. Cell (2002) 8.01
Retracted DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol (2007) 4.45
SRC-1 and TIF2 control energy balance between white and brown adipose tissues. Cell (2002) 4.31
Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev (2004) 3.74
A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors. Nature (2009) 3.63
Brivanib versus sorafenib as first-line therapy in patients with unresectable, advanced hepatocellular carcinoma: results from the randomized phase III BRISK-FL study. J Clin Oncol (2013) 3.45
Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nat Rev Cancer (2009) 3.33
Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science (2008) 3.17
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell (2006) 3.09
Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist. Proc Natl Acad Sci U S A (2002) 3.01
Analysis of the human endogenous coregulator complexome. Cell (2011) 2.97
Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell (2004) 2.95
Apatinib for chemotherapy-refractory advanced metastatic gastric cancer: results from a randomized, placebo-controlled, parallel-arm, phase II trial. J Clin Oncol (2013) 2.69
SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell (2007) 2.69
Nuclear receptor coregulators and human disease. Endocr Rev (2007) 2.65
Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metab (2011) 2.61
Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metab (2010) 2.58
The expanding cosmos of nuclear receptor coactivators. Cell (2006) 2.57
An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell (2007) 2.57
Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science (2002) 2.53
Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases. Science (2011) 2.52
Retracted Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell (2009) 2.48
Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Biochemistry (2010) 2.48
Sunitinib versus sorafenib in advanced hepatocellular cancer: results of a randomized phase III trial. J Clin Oncol (2013) 2.46
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol (2002) 2.45
The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions. Nat Genet (2012) 2.33
Transoral robotic surgery for advanced oropharyngeal carcinoma. Arch Otolaryngol Head Neck Surg (2010) 2.31
Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway. Mol Cell (2007) 2.31
Transoral robotic surgery: radical tonsillectomy. Arch Otolaryngol Head Neck Surg (2007) 2.28
SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell (2010) 2.18
Epigenetic suppression of GAD65 expression mediates persistent pain. Nat Med (2011) 2.17
AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Res (2004) 2.07
Minireview: nuclear receptor coactivators--an update. Endocrinology (2002) 2.04
Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event. Proc Natl Acad Sci U S A (2007) 2.03
Feasibility of near-infrared spectroscopic tomography for intraoperative functional cerebral monitoring: a primate study. J Thorac Cardiovasc Surg (2014) 2.02
Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. J Clin Oncol (2007) 2.02
Characterizing the risk assessment of heavy metals and sampling uncertainty analysis in paddy field by geostatistics and GIS. Environ Pollut (2005) 2.00
Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms. Cell Res (2011) 1.99
Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly. Mol Cell Biol (2006) 1.94
Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption. Cell Metab (2011) 1.89
Genetic dissection of intermated recombinant inbred lines using a new genetic map of maize. Genetics (2006) 1.89
Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics (2010) 1.88
Lysophosphatidic acid induces neointima formation through PPARgamma activation. J Exp Med (2004) 1.86
Identification and mechanism of ABA receptor antagonism. Nat Struct Mol Biol (2010) 1.83
Reproductive functions of progesterone receptors. Recent Prog Horm Res (2002) 1.82
Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. Mol Cell (2005) 1.82
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proc Natl Acad Sci U S A (2008) 1.80
Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Nat Genet (2012) 1.78
CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicing. Mol Cell Biol (2004) 1.77
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol (2008) 1.75
Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. Mol Endocrinol (2005) 1.74
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol (2003) 1.73
Examination performance of graduate entry medical students compared with mainstream students. J R Soc Med (2009) 1.72
Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator. Proc Natl Acad Sci U S A (2005) 1.72
Streamlined analysis schema for high-throughput identification of endogenous protein complexes. Proc Natl Acad Sci U S A (2010) 1.72
rpoB Gene mutations and molecular characterization of rifampin-resistant Mycobacterium tuberculosis isolates from Shandong Province, China. J Clin Microbiol (2006) 1.68
Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta. Mol Cell (2005) 1.66
Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Proc Natl Acad Sci U S A (2013) 1.66
Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A (2008) 1.62
A novel LacZ reporter mouse reveals complex regulation of the progesterone receptor promoter during mammary gland development. Mol Endocrinol (2002) 1.61
Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol (2008) 1.60
Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res (2005) 1.60
Rapid increase of serum neuron specific enolase level and tachyphylaxis of EGFR-tyrosine kinase inhibitor indicate small cell lung cancer transformation from EGFR positive lung adenocarcinoma? Lung Cancer (2013) 1.59
Identification of a lysosomal pathway that modulates glucocorticoid signaling and the inflammatory response. Sci Signal (2011) 1.58
Expanding functional diversity of the coactivators. Trends Biochem Sci (2005) 1.57
SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. Mol Cell (2006) 1.57
Steroid receptor coactivator (SRC) family: masters of systems biology. J Biol Chem (2010) 1.57
Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet (2013) 1.56
The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis. Cell Res (2010) 1.56
Nuclear receptor coregulators: modulators of pathology and therapeutic targets. Nat Rev Endocrinol (2012) 1.55
Mitochondrial localization of telomeric protein TIN2 links telomere regulation to metabolic control. Mol Cell (2012) 1.55
In vitro and in vivo evaluation of recombinant silk-elastinlike hydrogels for cancer gene therapy. J Control Release (2004) 1.53
In vivo activation of PPAR target genes by RXR homodimers. EMBO J (2004) 1.53
The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Res (2008) 1.53
Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest (2015) 1.53
Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol (2006) 1.52
Transoral robotic surgery: supraglottic partial laryngectomy. Ann Otol Rhinol Laryngol (2007) 1.51
Transoral robotic surgery: a multicenter study to assess feasibility, safety, and surgical margins. Laryngoscope (2012) 1.49
Computation of octanol-water partition coefficients by guiding an additive model with knowledge. J Chem Inf Model (2007) 1.49
Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol (2009) 1.49
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A (2006) 1.49
The steroid receptor coactivator-1 regulates twist expression and promotes breast cancer metastasis. Cancer Res (2009) 1.48
Elf5 inhibits TGF-β-driven epithelial-mesenchymal transition in prostate cancer by repressing SMAD3 activation. Prostate (2015) 1.47