Published in Proc Natl Acad Sci U S A on December 09, 1997
Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection. Clin Microbiol Rev (1998) 4.03
Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection. Infect Immun (2005) 2.66
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17. J Exp Med (2009) 2.28
Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice. J Exp Med (1998) 1.74
Screening for Toxoplasma gondii-regulated transcriptional responses in lipopolysaccharide-activated macrophages. Infect Immun (2006) 1.67
NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease. Am J Pathol (2000) 1.67
CCR5 is essential for NK cell trafficking and host survival following Toxoplasma gondii infection. PLoS Pathog (2006) 1.45
Curcumin, the major component of food flavour turmeric, reduces mucosal injury in trinitrobenzene sulphonic acid-induced colitis. Br J Pharmacol (2003) 1.38
Both expansion of regulatory GR1+ CD11b+ myeloid cells and anergy of T lymphocytes participate in hyporesponsiveness of the lung-associated immune system during acute toxoplasmosis. Infect Immun (2004) 1.31
The multiplex function of nitric oxide in (auto)immunity. J Exp Med (1998) 1.29
The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments. Infect Immun (2002) 1.28
Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase. Gut (1999) 1.19
Subversion of innate and adaptive immune responses by Toxoplasma gondii. Parasitol Res (2006) 1.16
Toxoplasma gondii infection reveals a novel regulatory role for galectin-3 in the interface of innate and adaptive immunity. Am J Pathol (2006) 1.14
A patatin-like protein protects Toxoplasma gondii from degradation in activated macrophages. Mol Microbiol (2006) 1.12
Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii. MBio (2014) 1.09
The CD8 T-cell road to immunotherapy of toxoplasmosis. Immunotherapy (2011) 1.08
Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger. Immunol Cell Biol (2011) 1.07
Role of gamma interferon in cellular immune response against murine Encephalitozoon cuniculi infection. Infect Immun (1999) 1.04
Dual transcriptional profiling of mice and Toxoplasma gondii during acute and chronic infection. BMC Genomics (2014) 1.01
Toll-like receptor-4-mediated macrophage activation is differentially regulated by progesterone via the glucocorticoid and progesterone receptors. Immunology (2008) 0.99
Soluble factors released by Toxoplasma gondii-infected astrocytes down-modulate nitric oxide production by gamma interferon-activated microglia and prevent neuronal degeneration. Infect Immun (2003) 0.99
Toxoplasma gondii cyclophilin 18-mediated production of nitric oxide induces Bradyzoite conversion in a CCR5-dependent manner. Infect Immun (2009) 0.96
Detrimental role of endogenous nitric oxide in host defence against Sporothrix schenckii. Immunology (2008) 0.96
Role of cytokines and major histocompatibility complex restriction in mouse resistance to infection with a natural recombinant strain (type I-III) of Toxoplasma gondii. Infect Immun (2003) 0.96
Lack of IL-15 results in the suboptimal priming of CD4+ T cell response against an intracellular parasite. Proc Natl Acad Sci U S A (2006) 0.96
The unexpected role for the aryl hydrocarbon receptor on susceptibility to experimental toxoplasmosis. J Biomed Biotechnol (2010) 0.94
Toxoplasma gondii clonal strains all inhibit STAT1 transcriptional activity but polymorphic effectors differentially modulate IFNγ induced gene expression and STAT1 phosphorylation. PLoS One (2012) 0.94
A DNA vaccine encoding for TcSSP4 induces protection against acute and chronic infection in experimental Chagas disease. Int J Biol Sci (2011) 0.93
Coinfection with Heligmosomoides polygyrus fails to establish CD8+ T-cell immunity against Toxoplasma gondii. Infect Immun (2008) 0.92
Molecular markers of susceptibility to ocular toxoplasmosis, host and guest behaving badly. Clin Ophthalmol (2008) 0.92
Infection with Toxoplasma gondii reduces established and developing Th2 responses induced by Nippostrongylus brasiliensis infection. Infect Immun (2004) 0.92
The impact of Toll-like-receptor-9 on intestinal microbiota composition and extra-intestinal sequelae in experimental Toxoplasma gondii induced ileitis. Gut Pathog (2014) 0.90
Distinct roles for nitric oxide in resistant C57BL/6 and susceptible BALB/c mice to control Burkholderia pseudomallei infection. BMC Immunol (2011) 0.90
ACG Clinical Guideline: Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults. Am J Gastroenterol (2016) 0.90
Inducible nitric oxide synthase is not essential for control of Trypanosoma cruzi infection in mice. Infect Immun (2004) 0.89
Interferon-γ restricts Toxoplasma gondii development in murine skeletal muscle cells via nitric oxide production and immunity-related GTPases. PLoS One (2012) 0.87
Ups and downs of mucosal cellular immunity against protozoan parasites. Infect Immun (2001) 0.87
Pituitary adenylate cyclase-activating polypeptide ameliorates experimental acute ileitis and extra-intestinal sequelae. PLoS One (2014) 0.84
NADPH oxidase deficient mice develop colitis and bacteremia upon infection with normally avirulent, TTSS-1- and TTSS-2-deficient Salmonella Typhimurium. PLoS One (2013) 0.84
Toxoplasma gondii and the blood-brain barrier. Virulence (2012) 0.82
Response of macrophage Toll-like receptor 4 to a Sporothrix schenckii lipid extract during experimental sporotrichosis. Immunology (2009) 0.81
Treatment with interleukin-18 binding protein ameliorates Toxoplasma gondii-induced small intestinal pathology that is induced by bone marrow cell-derived interleukin-18. Eur J Microbiol Immunol (Bp) (2012) 0.81
Pro-inflammatory potential of Escherichia coli strains K12 and Nissle 1917 in a murine model of acute ileitis. Eur J Microbiol Immunol (Bp) (2013) 0.81
Oxidative stress and tryptophan degradation pattern of acute Toxoplasma gondii infection in mice. Parasitol Res (2012) 0.81
Interaction of natural killer cells with Trypanosoma cruzi-infected fibroblasts. Clin Exp Immunol (2006) 0.80
Inducible nitric oxide synthase inhibitors ameliorate hypermotility observed after T. spiralis infection in the rat. Dig Dis Sci (2003) 0.80
TgMAPK1 is a Toxoplasma gondii MAP kinase that hijacks host MKK3 signals to regulate virulence and interferon-γ-mediated nitric oxide production. Exp Parasitol (2013) 0.80
Use and abuse of dendritic cells by Toxoplasma gondii. Virulence (2012) 0.79
Lack of a Functioning P2X7 Receptor Leads to Increased Susceptibility to Toxoplasmic Ileitis. PLoS One (2015) 0.79
Anti-Inflammatory Properties of NAP in Acute Toxoplasma Gondii-Induced Ileitis in Mice. Eur J Microbiol Immunol (Bp) (2015) 0.77
Nitric oxide stimulates early egress of Toxoplasma gondii tachyzoites from Human foreskin fibroblast cells. Parasit Vectors (2015) 0.77
Interleukin 23 in Crohn's disease. Inflamm Bowel Dis (2014) 0.77
Forward genetics screens using macrophages to identify Toxoplasma gondii genes important for resistance to IFN-γ-dependent cell autonomous immunity. J Vis Exp (2015) 0.76
MIF Promotes Classical Activation and Conversion of Inflammatory Ly6C(high) Monocytes into TipDCs during Murine Toxoplasmosis. Mediators Inflamm (2016) 0.76
Experimental Models of Ocular Infection with Toxoplasma Gondii. Eur J Microbiol Immunol (Bp) (2015) 0.75
STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System. MBio (2016) 0.75
Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J Exp Med (1983) 14.08
Interferon-gamma: the major mediator of resistance against Toxoplasma gondii. Science (1988) 7.96
Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc Natl Acad Sci U S A (1997) 7.90
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell (1995) 7.13
Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction. J Clin Microbiol (1989) 5.85
Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii. J Immunol (1994) 4.86
Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science (1994) 4.50
Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma. J Immunol (1985) 3.85
Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii. J Exp Med (1997) 3.62
Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J Exp Med (1996) 2.97
The effect of anti-IFN-gamma antibody on the protective effect of Lyt-2+ immune T cells against toxoplasmosis in mice. J Immunol (1990) 2.47
Interleukin-12 enhances murine survival against acute toxoplasmosis. Infect Immun (1994) 2.39
Nonspecific defence mechanism: the role of nitric oxide. Immunol Today (1991) 2.37
Cytokine-induced synthesis of nitrogen oxides in macrophages: a protective host response to Leishmania and other intracellular pathogens. J Leukoc Biol (1991) 2.30
Effect of murine interferon gamma on murine toxoplasmosis. J Infect Dis (1984) 2.27
Role of inorganic nitrogen oxides and tumor necrosis factor alpha in killing Leishmania donovani amastigotes in gamma interferon-lipopolysaccharide-activated macrophages from Lshs and Lshr congenic mouse strains. Infect Immun (1991) 1.84
Killing of Leishmania parasites in activated murine macrophages is based on an L-arginine-dependent process that produces nitrogen derivatives. J Leukoc Biol (1991) 1.69
Immune responses associated with early survival after peroral infection with Toxoplasma gondii. J Immunol (1989) 1.63
Toxoplasma gondii oral infection induces specific cytotoxic CD8 alpha/beta+ Thy-1+ gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes. J Immunol (1994) 1.50
Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii. Infect Immun (1997) 1.44
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice. J Immunol (1996) 1.44
IL-10 mediates immunosuppression following primary infection with Toxoplasma gondii in mice. Parasite Immunol (1995) 1.38
Production of nitric oxide (NO) is not essential for protection against acute Toxoplasma gondii infection in IRF-1-/- mice. J Immunol (1996) 1.31
Mucosal and systemic cellular immune responses induced by Toxoplasma gondii antigens in cyst orally infected mice. Immunology (1993) 1.23
IL-7 stimulates protective immunity in mice against the intracellular pathogen, Toxoplasma gondii. J Immunol (1995) 1.07
Production of tumor necrosis factor alpha by resident and activated murine macrophages. J Leukoc Biol (1992) 1.05
A role for TNF during African trypanosomiasis: involvement in parasite control, immunosuppression and pathology. Res Immunol (1993) 1.00
The cachexia associated with Trypanosoma cruzi acute infection in mice is attenuated by anti-TNF-alpha, but not by anti-IL-6 or anti-IFN-gamma antibodies. Parasite Immunol (1995) 0.96
Toxoplasma gondii: fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts. Science (1990) 4.65
Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii. J Immunol (1988) 3.98
Detection of respiratory syncytial virus in nasal secretions from infants by enzyme-linked immunosorbent assay. J Infect Dis (1979) 3.49
IP-10 is critical for effector T cell trafficking and host survival in Toxoplasma gondii infection. Immunity (2000) 2.58
Paroxysmal kinesigenic dyskinesia and infantile convulsions: clinical and linkage studies. Neurology (2000) 2.48
RAE1 is a shuttling mRNA export factor that binds to a GLEBS-like NUP98 motif at the nuclear pore complex through multiple domains. J Cell Biol (1999) 2.42
Interleukin-12 enhances murine survival against acute toxoplasmosis. Infect Immun (1994) 2.39
Purification of a major membrane protein of Toxoplasma gondii by immunoabsorption with a monoclonal antibody. J Immunol (1983) 2.38
Genetic mutations in exons 3 and 4 of the pancreatic secretory trypsin inhibitor in patients with pancreatitis. J Gastroenterol (2001) 2.17
Changing the needle when inoculating blood cultures. A no-benefit and high-risk procedure. JAMA (1990) 2.04
A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease. Mucosal Immunol (2010) 2.02
Insulin secretion and insulin sensitivity at different stages of glucose tolerance: a cross-sectional study of Japanese type 2 diabetes. Metabolism (2004) 1.82
Surface modifications for antifouling membranes. Chem Rev (2010) 1.80
Clinical and genetic analysis of four Mexican families with spinocerebellar ataxia type 10. Ann Neurol (2001) 1.74
Antibodies to Toxoplasma gondii major surface protein (SAG-1, P30) inhibit infection of host cells and are produced in murine intestine after peroral infection. J Immunol (1993) 1.71
Identification of stage-specific sporozoite antigens of Toxoplasma gondii by monoclonal antibodies. J Immunol (1984) 1.71
Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function. Proc Natl Acad Sci U S A (2001) 1.62
Recognition and characterization of stage-specific oocyst/sporozoite antigens of Toxoplasma gondii by human antisera. J Clin Invest (1985) 1.61
Attachment of Toxoplasma gondii to host cells involves major surface protein, SAG-1 (P30). Exp Parasitol (1994) 1.58
Strain-specific antigens of Toxoplasma gondii. Infect Immun (1987) 1.57
Huntington's disease--like 2 can present as chorea-acanthocytosis. Neurology (2003) 1.57
A Toxoplasma gondii rhoptry protein associated with host cell penetration has unusual charge asymmetry. Mol Biochem Parasitol (1992) 1.57
Different mixtures of sodium hyaluronate and their ability to create submucosal fluid cushions for endoscopic mucosal resection. Endoscopy (2004) 1.56
A purified parasite antigen (p30) mediates CD8+ T cell immunity against fatal Toxoplasma gondii infection in mice. J Immunol (1991) 1.55
Antigen-specific CD8+ T cell clone protects against acute Toxoplasma gondii infection in mice. J Immunol (1994) 1.54
Induction of antigen-specific parasiticidal cytotoxic T cell splenocytes by a major membrane protein (P30) of Toxoplasma gondii. J Immunol (1988) 1.54
Perineal group A streptococcal disease in a pediatric practice. Pediatrics (2000) 1.46
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice. J Immunol (1996) 1.44
Potent inhibitors of secretory phospholipase A2: synthesis and inhibitory activities of indolizine and indene derivatives. J Med Chem (1996) 1.41
Inhibition of Toxoplasma gondii replication by dinitroaniline herbicides. Exp Parasitol (1996) 1.39
Elevation of interleukin-6 in inflammatory bowel disease is macrophage- and epithelial cell-dependent. Dig Dis Sci (1995) 1.39
IL-10 mediates immunosuppression following primary infection with Toxoplasma gondii in mice. Parasite Immunol (1995) 1.38
The E6-Ap ubiquitin-protein ligase (UBE3A) gene is localized within a narrowed Angelman syndrome critical region. Genome Res (1997) 1.34
Localization of a Toxoplasma gondii rhoptry protein by immunoelectron microscopy during and after host cell penetration. J Protozool (1992) 1.34
Adoptive transfer of gut intraepithelial lymphocytes protects against murine infection with Toxoplasma gondii. J Immunol (1997) 1.33
Toxoplasma gondii: genetic crosses reveal phenotypic suppression of hydroxyurea resistance by fluorodeoxyuridine resistance. Exp Parasitol (1983) 1.33
Interleukin 4 in inflammatory bowel disease and mucosal immune reactivity. Gastroenterology (1996) 1.31
Production of nitric oxide (NO) is not essential for protection against acute Toxoplasma gondii infection in IRF-1-/- mice. J Immunol (1996) 1.31
CD8+ CTLs are essential for protective immunity against Encephalitozoon cuniculi infection. J Immunol (1999) 1.31
Neospora caninum: role for immune cytokines in host immunity. Exp Parasitol (1997) 1.29
Cryptogenic epilepsy: an infectious etiology? Epilepsia (2001) 1.29
Pyrrolidine inhibitors of human cytosolic phospholipase A(2). J Med Chem (2000) 1.28
Toxoplasma gondii: purine synthesis and salvage in mutant host cells and parasites. Exp Parasitol (1982) 1.27
Confocal endomicroscopy for the diagnosis of gastric cancer in vivo. Endoscopy (2006) 1.25
Murine ileitis after intracellular parasite infection is controlled by TGF-beta-producing intraepithelial lymphocytes. Gastroenterology (2001) 1.24
A novel class of unconventional myosins from Toxoplasma gondii. J Mol Biol (1997) 1.24
Isolation and characterization of a monoclonal antibody-resistant antigenic mutant of Toxoplasma gondii. J Immunol (1982) 1.22
Expression of a cell adhesion molecule, neuropilin, in the developing chick nervous system. Dev Biol (1995) 1.22
Differential infectivity and division of Toxoplasma gondii in human peripheral blood leukocytes. Infect Immun (2000) 1.21
An unexpected response to vaccination with a purified major membrane tachyzoite antigen (P30) of Toxoplasma gondii. J Immunol (1985) 1.21
The spectrum of mutations in UBE3A causing Angelman syndrome. Hum Mol Genet (1999) 1.21
The role of phospholipase in host cell penetration by Toxoplasma gondii. Am J Trop Med Hyg (1989) 1.20
The role of ataxin 10 in the pathogenesis of spinocerebellar ataxia type 10. Neurology (2006) 1.20
Mice lacking the chemokine receptor CCR1 show increased susceptibility to Toxoplasma gondii infection. J Immunol (2001) 1.19
Induction of antigen-specific human cytotoxic T cells by Toxoplasma gondii. J Clin Invest (1990) 1.19
Inhibition of a penetration-enhancing factor of Toxoplasma gondii by monoclonal antibodies specific for rhoptries. Infect Immun (1986) 1.17
Toxoplasma gondii: dithiol-induced Ca2+ flux causes egress of parasites from the parasitophorous vacuole. Exp Parasitol (1997) 1.17
Gut-derived intraepithelial lymphocytes induce long term immunity against Toxoplasma gondii. J Immunol (1998) 1.15
Attachment of Toxoplasma gondii to host cells is host cell cycle dependent. Infect Immun (1996) 1.14
Projectin is an invertebrate connectin (titin): isolation from crayfish claw muscle and localization in crayfish claw muscle and insect flight muscle. J Muscle Res Cell Motil (1990) 1.12
Activation-mediated CD4+ T cell unresponsiveness during acute Toxoplasma gondii infection in mice. Int Immunol (1996) 1.11
Minocycline-related lupus. Lancet (1993) 1.11
Isolation of Chlamydia trachomatis from infant lung tissue. N Engl J Med (1977) 1.09
Augmentation of the CD8+ T cell response by IFN-gamma in IL-12-deficient mice during Toxoplasma gondii infection. J Immunol (1999) 1.09
Influence of amyl nitrite inhalation on the systolic time intervals in normal subjects and in patients with ischemic heart disease. Circulation (1969) 1.08
Ultrastructural, immunocytochemical and stereological investigation of hepatocytes in a patient with the mutation of the ornithine transcarbamylase gene. Eur J Cell Biol (1995) 1.08
IL-7 stimulates protective immunity in mice against the intracellular pathogen, Toxoplasma gondii. J Immunol (1995) 1.07
Intraepithelial lymphocytes traffic to the intestine and enhance resistance to Toxoplasma gondii oral infection. J Immunol (1999) 1.07
Loss of interleukin-2-producing intestinal CD4+ T cells in inflammatory bowel disease. Gastroenterology (1991) 1.07
Gamma delta T cell-deficient mice have a down-regulated CD8+ T cell immune response against Encephalitozoon cuniculi infection. J Immunol (2001) 1.07
Induction of gammadelta T cells during acute murine infection with Toxoplasma gondii. J Immunol (1996) 1.06
Isolation and characterization of a monoclonal anti-P30 antibody resistant mutant of Toxoplasma gondii. Parasite Immunol (1987) 1.04
Immunofluorescent localization of myosin at the anterior pole of the coccidian, Toxoplasma gondii. J Protozool (1983) 1.04
Pseudobacteremia and use of the radiometric blood culture analyzer. Infect Control (1984) 1.04
Functional and quantitative analysis of splenic T cell immune responses following oral toxoplasma gondii infection in mice. Exp Parasitol (1999) 1.03
Brain activation patterns associated with working memory in relapsing-remitting MS. Neurology (2004) 1.03
Short report: An imported case of cystic echinococcosis in Japan diagnosed by imaging and serology with confirmation of Echinococcus granulosus-specific DNA sequences. Am J Trop Med Hyg (1998) 1.02
Phenotypic variability in male patients carrying the mutant ornithine transcarbamylase (OTC) allele, Arg40His, ranging from a child with an unfavourable prognosis to an asymptomatic older adult. J Med Genet (1996) 1.02
Retrospective survey of urea cycle disorders: Part 2. Neurological outcome in forty-nine Japanese patients with urea cycle enzymopathies. Am J Med Genet (1991) 1.02
Absence of a role for natural killer cells in the control of acute infection by Toxoplasma gondii oocysts. Clin Exp Immunol (1988) 1.02
Mixed matrix membrane incorporated with large pore size halloysite nanotubes (HNT) as filler for gas separation: experimental. J Colloid Interface Sci (2011) 1.02
Prevalence of possible adult T-cell leukemia virus-carriers among volunteer blood donors in Japan: a nation-wide study. Int J Cancer (1984) 1.01
Toxoplasma gondii: a monoclonal antibody that inhibits intracellular replication. Exp Parasitol (1994) 1.01
Mutations in the 4-hydroxyphenylpyruvic acid dioxygenase gene are responsible for tyrosinemia type III and hawkinsinuria. Mol Genet Metab (2000) 1.00
Invasiveness of hepatocellular carcinoma cell lines: contribution of membrane-type 1 matrix metalloproteinase. Neoplasia (1999) 1.00
Pyrimidine synthesis by intracellular Toxoplasma gondii. J Parasitol (1981) 0.99
Interleukin-6 and soluble interleukin-6 receptor in the colonic mucosa of inflammatory bowel disease. J Gastroenterol Hepatol (1999) 0.98
Distribution and clinical significance of the autonomic nervous system in the human nasal mucosa. Acta Otolaryngol (1972) 0.98
Immune CD8(+) T cells prevent reactivation of Toxoplasma gondii infection in the immunocompromised host. Infect Immun (1999) 0.98