Published in J Immunol on October 01, 1993
Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection. Clin Microbiol Rev (1998) 4.03
Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii. J Exp Med (1997) 3.62
Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J Exp Med (1994) 2.99
Transforming growth factor beta: the good, the bad, and the ugly. J Exp Med (1994) 2.86
Lytic cycle of Toxoplasma gondii. Microbiol Mol Biol Rev (2000) 2.84
Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J Exp Med (1994) 2.46
Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase. J Exp Med (1996) 2.45
Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum. Nat Immunol (2008) 2.45
Reduced replication of Toxoplasma gondii is necessary for induction of bradyzoite-specific antigens: a possible role for nitric oxide in triggering stage conversion. Infect Immun (1994) 2.26
Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice. J Exp Med (1996) 2.19
Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice. Clin Exp Immunol (1999) 1.97
Role of nitric oxide in parasitic infections. Microbiol Rev (1995) 1.91
A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice. Proc Natl Acad Sci U S A (1997) 1.80
Biochemical characterization and protein kinase C dependency of monokine-inducing activities of Toxoplasma gondii. Infect Immun (1996) 1.79
Definitive identification of a gene that confers resistance against Toxoplasma cyst burden and encephalitis. Immunology (1995) 1.76
Interferon (IFN) consensus sequence-binding protein, a transcription factor of the IFN regulatory factor family, regulates immune responses in vivo through control of interleukin 12 expression. J Exp Med (1997) 1.73
Interleukin-10 modulates susceptibility in experimental cerebral malaria. Immunology (1997) 1.73
A role for CD4+ NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection. J Exp Med (1996) 1.70
NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease. Am J Pathol (2000) 1.67
Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP. Infect Immun (2001) 1.66
Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction. J Exp Med (1997) 1.64
Pulmonary and hepatic gene expression following cecal ligation and puncture: monophosphoryl lipid A prophylaxis attenuates sepsis-induced cytokine and chemokine expression and neutrophil infiltration. Infect Immun (1998) 1.49
Expression of cytokines and inducible nitric oxide synthase mRNA in the lungs of mice infected with Cryptococcus neoformans: effects of interleukin-12. Infect Immun (1997) 1.39
Immune response and immunopathology during toxoplasmosis. Semin Immunopathol (2012) 1.38
Effect of cytokines on growth of Toxoplasma gondii in murine astrocytes. Infect Immun (1998) 1.37
Old mice are able to control low-dose aerogenic infections with Mycobacterium tuberculosis. Infect Immun (1995) 1.36
Clearance of Chlamydia trachomatis from the murine genital mucosa does not require perforin-mediated cytolysis or Fas-mediated apoptosis. Infect Immun (1999) 1.35
Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade. Proc Natl Acad Sci U S A (2011) 1.34
Impaired resistance to the development of toxoplasmic encephalitis in interleukin-6-deficient mice. Infect Immun (1997) 1.34
The CD40/CD40 ligand interaction is required for resistance to toxoplasmic encephalitis. Infect Immun (2000) 1.31
Inhibition of nitric oxide synthesis increases mortality in Sindbis virus encephalitis. J Virol (1996) 1.25
Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells. PLoS Pathog (2010) 1.25
In vivo regulation of nitric oxide production by tumor necrosis factor alpha and gamma interferon, but not by interleukin-4, during blood stage malaria in mice. Infect Immun (1996) 1.24
Requirement of non-T cells that produce gamma interferon for prevention of reactivation of Toxoplasma gondii infection in the brain. Infect Immun (2001) 1.23
Adequate expression of protective immunity in the absence of granuloma formation in Mycobacterium tuberculosis-infected mice with a disruption in the intracellular adhesion molecule 1 gene. Infect Immun (1998) 1.22
Interleukin-18 (IL-18) enhances innate IL-12-mediated resistance to Toxoplasma gondii. Infect Immun (2000) 1.21
Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein. J Virol (1998) 1.20
Cationic amino acid transporter-2 regulates immunity by modulating arginase activity. PLoS Pathog (2008) 1.19
Antibody against interleukin-6 reduces inflammation and numbers of cysts in brains of mice with toxoplasmic encephalitis. Infect Immun (1994) 1.18
Dynamics of the intracerebral and splenic cytokine mRNA production in Toxoplasma gondii-resistant and -susceptible congenic strains of mice. Immunology (1995) 1.15
In vivo treatment with interleukin 12 protects mice from immune abnormalities observed during murine acquired immunodeficiency syndrome (MAIDS). J Exp Med (1994) 1.14
Expression pattern and cellular origin of cytokines in the normal and Toxoplasma gondii-infected murine brain. Am J Pathol (1997) 1.11
Investigation into the mechanism of gamma interferon-mediated inhibition of Toxoplasma gondii in murine astrocytes. Infect Immun (2000) 1.10
Protective role of nitric oxide in Staphylococcus aureus infection in mice. Infect Immun (1998) 1.10
Tumor necrosis factor expression during mouse hepatitis virus-induced demyelinating encephalomyelitis. J Virol (1995) 1.10
Murine AIDS is an antigen-driven disease: requirements for major histocompatibility complex class II expression and CD4+ T cells. J Virol (1994) 1.09
Inhibition of leukocyte rolling by nitric oxide during sepsis leads to reduced migration of active microbicidal neutrophils. Infect Immun (2002) 1.09
Gamma interferon production, but not perforin-mediated cytolytic activity, of T cells is required for prevention of toxoplasmic encephalitis in BALB/c mice genetically resistant to the disease. Infect Immun (2004) 1.08
The CD8 T-cell road to immunotherapy of toxoplasmosis. Immunotherapy (2011) 1.08
In the absence of endogenous gamma interferon, mice acutely infected with Neospora caninum succumb to a lethal immune response characterized by inactivation of peritoneal macrophages. Clin Diagn Lab Immunol (2001) 1.07
An inside job: hacking into Janus kinase/signal transducer and activator of transcription signaling cascades by the intracellular protozoan Toxoplasma gondii. Infect Immun (2011) 1.06
Transforming growth factor beta-induced failure of resistance to infection with blood-stage Plasmodium chabaudi in mice. Infect Immun (1999) 1.03
The immunology of parasite infections in immunocompromised hosts. Parasite Immunol (2006) 1.01
Monoclonal rat antibodies directed against Toxoplasma gondii suitable for studying tachyzoite-bradyzoite interconversion in vivo. Clin Diagn Lab Immunol (1995) 1.00
Cytokine-mediated activation of macrophages from Mycobacterium bovis BCG-resistant and -susceptible mice: differential effects of corticosterone on antimycobacterial activity and expression of the Bcg gene (Candidate Nramp). Infect Immun (1995) 0.99
Brain injury-associated biomarkers of TGF-beta1, S100B, GFAP, NF-L, tTG, AbetaPP, and tau were concomitantly enhanced and the UPS was impaired during acute brain injury caused by Toxocara canis in mice. BMC Infect Dis (2008) 0.98
The role of nitric oxide in mycobacterial infections. Immune Netw (2009) 0.97
Toxoplasma gondii cyclophilin 18-mediated production of nitric oxide induces Bradyzoite conversion in a CCR5-dependent manner. Infect Immun (2009) 0.96
Role of cytokines and major histocompatibility complex restriction in mouse resistance to infection with a natural recombinant strain (type I-III) of Toxoplasma gondii. Infect Immun (2003) 0.96
Gamma interferon is not essential in host defense against disseminated candidiasis in mice. Infect Immun (1997) 0.96
PD-1-mediated attrition of polyfunctional memory CD8+ T cells in chronic toxoplasma infection. J Infect Dis (2012) 0.95
Stabilized expression of mRNA is associated with mycobacterial resistance controlled by Nramp1. Infect Immun (1997) 0.94
Long-term immunity to lethal acute or chronic type II Toxoplasma gondii infection is effectively induced in genetically susceptible C57BL/6 mice by immunization with an attenuated type I vaccine strain. Infect Immun (2009) 0.93
Toxoplasma gondii triggers granulocyte-dependent cytokine-mediated lethal shock in D-galactosamine-sensitized mice. Infect Immun (1998) 0.93
Infection of human immunodeficiency virus 1 transgenic mice with Toxoplasma gondii stimulates proviral transcription in macrophages in vivo. J Exp Med (1996) 0.93
Expression of Toxoplasma gondii-specific heat shock protein 70 during In vivo conversion of bradyzoites to tachyzoites. Infect Immun (1998) 0.93
Retrovirus-elicited interleukin-12 and tumour necrosis factor-alpha as inducers of interferon-gamma-mediated pathology in mouse AIDS. Immunology (1996) 0.93
Toxoplasma gondii infection of neurons induces neuronal cytokine and chemokine production, but gamma interferon- and tumor necrosis factor-stimulated neurons fail to inhibit the invasion and growth of T. gondii. Infect Immun (2001) 0.92
The CD40-autophagy pathway is needed for host protection despite IFN-Γ-dependent immunity and CD40 induces autophagy via control of P21 levels. PLoS One (2010) 0.90
SAG2A protein from Toxoplasma gondii interacts with both innate and adaptive immune compartments of infected hosts. Parasit Vectors (2013) 0.89
LC-MS metabolomics of psoriasis patients reveals disease severity-dependent increases in circulating amino acids that are ameliorated by anti-TNFα treatment. J Proteome Res (2014) 0.86
Chemokine synthesis and cellular inflammatory changes in lungs of mice bearing p40tax of human T-lymphotropic virus type 1. Clin Exp Immunol (2000) 0.85
Effects of exogenous, nonleukemogenic, ecotropic murine leukemia virus infections on the immune systems of adult C57BL/6 mice. J Virol (1995) 0.85
Vasopressin release during endotoxaemic shock in mice lacking inducible nitric oxide synthase. Pflugers Arch (2005) 0.84
Protective role of nitric oxide in ocular toxoplasmosis. Br J Ophthalmol (1996) 0.84
NF-kappaB1 contributes to T cell-mediated control of Toxoplasma gondii in the CNS. J Neuroimmunol (2010) 0.84
Production of tumor necrosis factor and nitric oxide by macrophages infected with live and dead mycobacteria and their suppression by an interleukin-10-secreting recombinant. Infect Immun (1997) 0.83
Interactions between murine AIDS (MAIDS) and toxoplasmosis in co-infected mice. Clin Exp Immunol (1994) 0.82
The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen. PLoS Pathog (2013) 0.81
Protective Toxoplasma gondii-specific T-cell responses require T-cell-specific expression of protein kinase C-theta. Infect Immun (2010) 0.81
TgMAPK1 is a Toxoplasma gondii MAP kinase that hijacks host MKK3 signals to regulate virulence and interferon-γ-mediated nitric oxide production. Exp Parasitol (2013) 0.80
Different strains of Toxoplasma gondii induce different cytokine responses in CBA/Ca mice. Infect Immun (2003) 0.79
MAP kinase phosphatase-2 plays a key role in the control of infection with Toxoplasma gondii by modulating iNOS and arginase-1 activities in mice. PLoS Pathog (2013) 0.79
Dietary supplementation with Echinacea and development of immunity to challenge infection with coccidia. Parasitol Res (2003) 0.78
Production, regulation and role of nitric oxide in glial cells. Mediators Inflamm (1998) 0.77
A toxoplasma patatin-like protein changes localization and alters the cytokine response during toxoplasmic encephalitis. Infect Immun (2013) 0.77
Effect of route of infection on outcome of Toxoplasma gondii infection in hu-PBL SCID mice. Eur J Microbiol Immunol (Bp) (2013) 0.77
The morphological analysis of autophagy in primary skeletal muscle cells infected with Toxoplasma gondii. Parasitol Res (2016) 0.76
Endogenous Mtv-encoded superantigens are not required for development of murine AIDS. J Virol (1996) 0.76
CD103(+) CD8 T Cells in the Toxoplasma-Infected Brain Exhibit a Tissue-Resident Memory Transcriptional Profile. Front Immunol (2017) 0.75
In vivo effect of anti-TNF agent (etanercept) in reactivation of latent toxoplasmosis. J Parasit Dis (2015) 0.75
Toxoplasma Effectors Targeting Host Signaling and Transcription. Clin Microbiol Rev (2017) 0.75
Preventive effect of pidotimod on reactivated toxoplasmosis in mice. Parasitol Res (2013) 0.75
Functional diversity of helper T lymphocytes. Nature (1996) 18.09
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol (2000) 14.74
Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J Exp Med (1988) 7.02
Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc Natl Acad Sci U S A (1993) 6.87
In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas. J Exp Med (1997) 6.53
Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming. Proc Natl Acad Sci U S A (1993) 6.12
Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J Exp Med (1991) 5.04
Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii. J Immunol (1994) 4.86
T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells. Proc Natl Acad Sci U S A (2001) 4.76
Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine. J Immunol (1991) 4.69
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism. J Immunol (2001) 4.59
An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response. J Clin Invest (1999) 4.22
Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii. J Immunol (1992) 4.02
IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages. J Immunol (1992) 3.98
Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism. Infect Immun (1998) 3.80
Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. J Immunol (1991) 3.65
Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection. J Exp Med (2001) 3.64
The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. J Exp Med (2001) 3.63
Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii. J Exp Med (1997) 3.62
Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J Immunol (1993) 3.34
CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity (2000) 3.27
Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production. J Immunol (2001) 3.25
Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease. Immunol Rev (1989) 3.21
Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals. J Clin Invest (1993) 3.19
In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection. J Immunol (1996) 3.15
Pulmonary fibrosis: pathogenesis, etiology and regulation. Mucosal Immunol (2009) 3.13
Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus. J Clin Invest (1994) 3.12
Inheritance of an idiotype associated with the immune response of inbred mice to phosphorylcholine. Eur J Immunol (1972) 3.04
IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis. J Immunol (2000) 3.03
Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J Exp Med (1994) 2.99
The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta. Eur J Immunol (1992) 2.98
Eosinophils as mediators of antibody-dependent damage to schistosomula. Nature (1975) 2.92
Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor alpha required as a costimulatory factor for interferon gamma-induced activation. Proc Natl Acad Sci U S A (1992) 2.92
Identification of cell surface carbohydrate and antigenic changes between noninfective and infective developmental stages of Leishmania major promastigotes. J Immunol (1985) 2.87
In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma. J Clin Invest (1993) 2.84
Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP. Proc Natl Acad Sci U S A (2000) 2.80
Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1. J Exp Med (1997) 2.79
IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity. J Immunol (1992) 2.78
Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance. Proc Natl Acad Sci U S A (1993) 2.65
Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile. J Immunol (2000) 2.52
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection. Nature (1995) 2.52
Successful T cell priming in B cell-deficient mice. J Exp Med (1995) 2.52
CCR5 provides a signal for microbial induced production of IL-12 by CD8 alpha+ dendritic cells. Nat Immunol (2000) 2.49
Diversity of cytokine synthesis and function of mouse CD4+ T cells. Immunol Rev (1991) 2.49
Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science (1999) 2.45
Vaccination against cutaneous leishmaniasis in a murine model. I. Induction of protective immunity with a soluble extract of promastigotes. J Immunol (1987) 2.43
Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro. Science (1993) 2.35
Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. Proc Natl Acad Sci U S A (2001) 2.29
Induction and regulation of IL-15 expression in murine macrophages. J Immunol (1996) 2.28
Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis. J Immunol (1994) 2.25
Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity. Science (2014) 2.20
Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen. J Immunol (1992) 2.14
IL-12-induced protection against blood-stage Plasmodium chabaudi AS requires IFN-gamma and TNF-alpha and occurs via a nitric oxide-dependent mechanism. J Immunol (1995) 2.12
Emergence of NK1.1+ cells as effectors of IFN-gamma dependent immunity to Toxoplasma gondii in MHC class I-deficient mice. J Exp Med (1993) 2.07
Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: cytokine requirements for the induction and maintenance of intestinal inflammation. Infect Immun (2001) 1.99
Acquisition of murine major histocompatibility complex gene products by schistosomula of Schistosoma mansoni. J Exp Med (1978) 1.98
Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity. Nat Immunol (2001) 1.97
Good worms or bad worms: do worm infections affect the epidemiological patterns of other diseases? Parasitol Today (2000) 1.96
Cutting edge: IL-12 is required for the maintenance of IFN-gamma production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii. J Immunol (2000) 1.94
IL-12 prevents mortality in mice infected with Histoplasma capsulatum through induction of IFN-gamma. J Immunol (1995) 1.94
Plasmodium falciparum histidine-rich protein 2-based immunocapture diagnostic assay for malaria: cross-reactivity with rheumatoid factors. J Clin Microbiol (2000) 1.92
IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs. J Immunol (1999) 1.91
Studies of murine schistosomiasis reveal interleukin-13 blockade as a treatment for established and progressive liver fibrosis. Hepatology (2001) 1.90
Fidelity of the ensemble code for visual motion in primate retina. J Neurophysiol (2004) 1.88
Regulation and biological function of helminth-induced cytokine responses. Immunol Today (1991) 1.87
Cell-mediated immunity to Toxoplasma gondii: initiation, regulation and effector function. Immunobiology (1999) 1.86
Immunization of mice against African trypanosomiasis using anti-idiotypic antibodies. J Exp Med (1982) 1.86
CD8+ T cells from mice vaccinated against Toxoplasma gondii are cytotoxic for parasite-infected or antigen-pulsed host cells. J Immunol (1991) 1.82
Biochemical characterization and protein kinase C dependency of monokine-inducing activities of Toxoplasma gondii. Infect Immun (1996) 1.79
Schistosome-infected IL-4 receptor knockout (KO) mice, in contrast to IL-4 KO mice, fail to develop granulomatous pathology while maintaining the same lymphokine expression profile. J Immunol (1999) 1.78
Vaccination against cutaneous leishmaniasis in a murine model. II. Immunologic properties of protective and nonprotective subfractions of soluble promastigote extract. J Immunol (1987) 1.75
Paralysis of dendritic cell IL-12 production by microbial products prevents infection-induced immunopathology. Immunity (1999) 1.72
Detection of in vivo expression of interleukin-10 using a semi-quantitative polymerase chain reaction method in Schistosoma mansoni infected mice. J Immunol Methods (1993) 1.70
A role for CD4+ NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection. J Exp Med (1996) 1.70
Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses. J Exp Med (1996) 1.68
Role of innate cytokines in mycobacterial infection. Mucosal Immunol (2011) 1.68
Comparison of the OptiMAL test with PCR for diagnosis of malaria in immigrants. J Clin Microbiol (1999) 1.67
NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease. Am J Pathol (2000) 1.67
Schistosoma mansoni: rapid isolation and purification of schistosomula of different developmental stages by centrifugation on discontinuous density gradients of Percoll. Exp Parasitol (1982) 1.66
Defects in cell-mediated immunity affect chronic, but not innate, resistance of mice to Mycobacterium avium infection. J Immunol (1997) 1.66
The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation. Mucosal Immunol (2010) 1.65
The role of dendritic cells in the induction and regulation of immunity to microbial infection. Curr Opin Immunol (1999) 1.64
Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction. J Exp Med (1997) 1.64
Mutation of Tec family kinases alters T helper cell differentiation. Nat Immunol (2001) 1.63
TNF-alpha, nitric oxide and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected perorally with Toxoplasma gondii. Parasite Immunol (1999) 1.63
CD4+ subset regulation in viral infection. Preferential activation of Th2 cells during progression of retrovirus-induced immunodeficiency in mice. J Immunol (1992) 1.62
Perforin-mediated cytolysis plays a limited role in host resistance to Toxoplasma gondii. J Immunol (1997) 1.60
IL-10 production by CD4+ effector T cells: a mechanism for self-regulation. Mucosal Immunol (2010) 1.59