Published in Oncogene on January 08, 1998
Human papillomavirus oncoproteins: pathways to transformation. Nat Rev Cancer (2010) 4.99
Mechanisms of human papillomavirus-induced oncogenesis. J Virol (2004) 3.95
Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling. J Cell Biol (1999) 3.34
Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells. J Cell Biol (2000) 2.13
Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion. J Cell Biol (2000) 1.95
The PDZ ligand domain of the human papillomavirus type 16 E6 protein is required for E6's induction of epithelial hyperplasia in vivo. J Virol (2003) 1.91
Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding. Proc Natl Acad Sci U S A (2005) 1.76
Molecular mechanisms of human papillomavirus-induced carcinogenesis. Public Health Genomics (2009) 1.45
PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein. Proc Natl Acad Sci U S A (1998) 1.41
Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin. Mol Biol Cell (1998) 1.39
Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase. J Virol (2000) 1.34
Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity. J Virol (2012) 1.28
Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling. Oncogene (2012) 1.27
Association of E6AP (UBE3A) with human papillomavirus type 11 E6 protein. Virology (2006) 1.22
Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins. Science (2013) 1.22
Papillomavirus E6 oncoproteins. Virology (2013) 1.21
Genetic analysis of high-risk e6 in episomal maintenance of human papillomavirus genomes in primary human keratinocytes. J Virol (2002) 1.19
A mutant of human papillomavirus type 16 E6 deficient in binding alpha-helix partners displays reduced oncogenic potential in vivo. J Virol (2002) 1.15
Degradation of tyrosine phosphatase PTPN3 (PTPH1) by association with oncogenic human papillomavirus E6 proteins. J Virol (2006) 1.14
Roles of the E6 and E7 proteins in the life cycle of low-risk human papillomavirus type 11. J Virol (2004) 1.11
Cutaneous β-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling. Proc Natl Acad Sci U S A (2012) 1.09
Interaction of paxillin with poly(A)-binding protein 1 and its role in focal adhesion turnover and cell migration. Mol Cell Biol (2005) 1.08
Interaction of zyxin, a focal adhesion protein, with the e6 protein from human papillomavirus type 6 results in its nuclear translocation. J Virol (2001) 1.01
Human papillomavirus type 16 E6 and E7 oncoproteins act synergistically to cause head and neck cancer in mice. Virology (2010) 1.00
Diverse roles for the paxillin family of proteins in cancer. Genes Cancer (2012) 0.98
Pitx2a binds to human papillomavirus type 18 E6 protein and inhibits E6-mediated P53 degradation in HeLa cells. J Biol Chem (2005) 0.96
Peptide interactions stabilize and restructure human papillomavirus type 16 E6 to interact with p53. J Virol (2012) 0.96
Activation of cap-dependent translation by mucosal human papillomavirus E6 proteins is dependent on the integrity of the LXXLL binding motif. J Virol (2012) 0.95
Human papillomavirus 16 E6 is associated with the nuclear matrix of esophageal carcinoma cells. World J Gastroenterol (2001) 0.94
The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species. PLoS Pathog (2013) 0.94
Identification of a second transforming function in bovine papillomavirus type 1 E6 and the role of E6 interactions with paxillin, E6BP, and E6AP. J Virol (2000) 0.93
Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS. J Biol Chem (2011) 0.92
Cooperative transformation and coexpression of bovine papillomavirus type 1 E5 and E7 proteins. J Virol (2001) 0.90
Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer. Cancer Biol Ther (2013) 0.89
Transformation by bovine papillomavirus type 1 E6 requires paxillin. J Virol (2008) 0.89
Bovine papillomavirus E7 oncoprotein inhibits anoikis. J Virol (2007) 0.89
Strategies for bacterial expression of protein-peptide complexes: application to solubilization of papillomavirus E6. Protein Expr Purif (2011) 0.86
Involvement of the paxillin pathway in JB6 Cl41 cell transformation. Cancer Res (2006) 0.84
Warts, cancer and ubiquitylation: lessons from the papillomaviruses. Trans Am Clin Climatol Assoc (2006) 0.82
The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63β upon transformation. PLoS Pathog (2011) 0.81
Human papillomavirus E6 regulates the cytoskeleton dynamics of keratinocytes through targeted degradation of p53. J Virol (2007) 0.79
FAK and paxillin, two potential targets in pancreatic cancer. Oncotarget (2016) 0.78
Interactions between E6, FAK, and GIT1 at paxillin LD4 are necessary for transformation by bovine papillomavirus 1 E6. J Virol (2014) 0.78
Mutagenic Potential ofBos taurus Papillomavirus Type 1 E6 Recombinant Protein: First Description. Biomed Res Int (2015) 0.75
Virus proteins similar to human proteins as possible disturbance on human pathways. Syst Synth Biol (2014) 0.75
Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J Cell Biol (1992) 7.97
Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins. Proc Natl Acad Sci U S A (1991) 5.76
The relative sensitivity to vibration of muscle receptors of the cat. J Physiol (1967) 4.68
Polyneuronal innervation of skeletal muscle in new-born rats and its elimination during maturation. J Physiol (1976) 3.63
Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling. J Cell Biol (1999) 3.34
Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve. Eur J Neurosci (1989) 3.24
Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nat Genet (1999) 3.24
Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding. J Cell Biol (1996) 2.63
Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase. J Biol Chem (1995) 2.44
Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells. J Cell Biol (2000) 2.13
Detection of Src homology 3-binding proteins, including paxillin, in normal and v-Src-transformed Balb/c 3T3 cells. J Biol Chem (1993) 2.11
The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL). J Cell Biol (2001) 2.10
Public Health Degrees Granted in 1934 : Report of the Committee on Professional Education. Am J Public Health Nations Health (1935) 2.03
Sprouting and regression of neuromuscular synapses in partially denervated mammalian muscles. J Physiol (1978) 2.01
Role of alpha9 nicotinic ACh receptor subunits in the development and function of cochlear efferent innervation. Neuron (1999) 2.01
Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion. J Cell Biol (2000) 1.95
Motor nerve sprouting. Annu Rev Neurosci (1981) 1.91
Effectiveness of Radio in Health Education. Am J Public Health Nations Health (1935) 1.82
Physiology and anatomy of single olivocochlear neurons in the cat. Hear Res (1986) 1.81
Characterisation of the paxillin-binding site and the C-terminal focal adhesion targeting sequence in vinculin. J Cell Sci (1994) 1.76
The macrophage response to central and peripheral nerve injury. A possible role for macrophages in regeneration. J Exp Med (1987) 1.75
Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions. J Biol Chem (2001) 1.73
Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin. J Cell Sci (1999) 1.72
Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells. Mol Biol Cell (1994) 1.67
A novel cholinergic "slow effect" of efferent stimulation on cochlear potentials in the guinea pig. J Neurosci (1995) 1.67
Contribution of the repeating domains of membrane cofactor protein (CD46) of the complement system to ligand binding and cofactor activity. J Immunol (1991) 1.63
After-effects of fusimotor stimulation on the response of muscle spindle primary afferent endings. J Physiol (1969) 1.63
An 85-kb tandem triplication in the slow Wallerian degeneration (Wlds) mouse. Proc Natl Acad Sci U S A (1998) 1.61
Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells. J Biol Chem (1993) 1.61
Motor neurone sprouting induced by prolonged tetrodotoxin block of nerve action potentials. Nature (1977) 1.56
Paxillin LD motifs may define a new family of protein recognition domains. Nat Struct Biol (1998) 1.52
Constituents of Cannabis sativa L. XVII. A review of the natural constituents. J Nat Prod (1980) 1.51
Static fusimotor fibres and the position sensitivity of muscle spindle receptors. Brain Res (1969) 1.46
Monocular and binocular depth discrimination thresholds. Optom Vis Sci (1999) 1.45
Inhibition of human lymphocyte rosetting by anti-T sera. Nat New Biol (1973) 1.45
Very Slow Retrograde and Wallerian Degeneration in the CNS of C57BL/Ola Mice. Eur J Neurosci (1991) 1.42
Malden Studies on Health Education and Growth. Am J Public Health Nations Health (1928) 1.40
Studies on the site of termination of static and dynamic fusimotor fibres within muscle spindles of the tenuissimus muscle of the cat. J Physiol (1973) 1.39
Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin. Mol Biol Cell (1998) 1.39
PUBLIC HEALTH TRAINING. Am J Public Health (N Y) (1926) 1.39
HEALTH TEACHING AND THE SCHOOL HEALTH PROGRAM. Am J Public Health (N Y) (1921) 1.38
Quantitative changes in integrin and focal adhesion signaling regulate myoblast cell cycle withdrawal. J Cell Biol (1999) 1.38
Paxillin-ARF GAP signaling and the cytoskeleton. Curr Opin Cell Biol (2001) 1.35
Functional studies of the domains of talin. J Cell Biol (1990) 1.35
Soluble CD8 during T cell activation. J Immunol (1989) 1.34
Unique postsynaptic signaling at the hair cell efferent synapse permits calcium to evoke changes on two time scales. J Neurosci (1997) 1.32
Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin. Biochem J (1997) 1.29
Evidence that Very Slow Wallerian Degeneration in C57BL/Ola Mice is an Intrinsic Property of the Peripheral Nerve. Eur J Neurosci (1990) 1.28
How To Improve Dental Conditions in the United States. Am J Public Health Nations Health (1939) 1.28
Efferent control of cochlear inner hair cell responses in the guinea-pig. J Physiol (1984) 1.27
Changing trends in hypertension detection and control: the Chicago experience. Am J Public Health (1980) 1.23
Nodal and terminal sprouting from motor nerves in fast and slow muscles of the mouse. J Physiol (1980) 1.20
Mice overexpressing genes from the 22q11 region deleted in velo-cardio-facial syndrome/DiGeorge syndrome have middle and inner ear defects. Hum Mol Genet (2001) 1.19
Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton. J Biol Chem (2000) 1.19
Radiation-induced reductions in macrophage recruitment have only slight effects on myelin degeneration in sectioned peripheral nerves of mice. Eur J Neurosci (1995) 1.18
An investigation into the site of termination of static gamma fibres within muscle spindles of the cat peroneus longus muscle. J Physiol (1975) 1.18
Intracellular recordings from cochlear inner hair cells: effects of stimulation of the crossed olivocochlear efferents. Science (1983) 1.15
A gene affecting Wallerian nerve degeneration maps distally on mouse chromosome 4. Proc Natl Acad Sci U S A (1993) 1.12
Effects of anesthesia on efferent-mediated adaptation of the DPOAE. J Assoc Res Otolaryngol (2002) 1.11
Evidence that the Rate of Wallerian Degeneration is Controlled by a Single Autosomal Dominant Gene. Eur J Neurosci (1990) 1.11
Evaluation of an automated blood pressure measuring device intended for general public use. Am J Public Health (1979) 1.11
Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST. J Biol Chem (1999) 1.11
Degenerating nerve products affect innervated muscle fibres. Nature (1978) 1.11
A central role for denervated tissues in causing nerve sprouting. Nature (1979) 1.11
Regeneration of afferent and efferent fibres to muscle spindles after nerve injury in adults cats. J Physiol (1976) 1.10
Morphology of labeled afferent fibers in the guinea pig cochlea. J Comp Neurol (1987) 1.10
Antidromic inhibition of presumed fusimotor neurones by repetitive stimulation of the ventral root in the decerebrate cat. Experientia (1968) 1.09
Postnatal development of the adult pattern of motor axon distribution in rat muscle. Nature (1983) 1.07
Morphology of labeled efferent fibers in the guinea pig cochlea. J Comp Neurol (1987) 1.07
Persistence of neuromuscular junctions after axotomy in mice with slow Wallerian degeneration (C57BL/WldS). Eur J Neurosci (1995) 1.07
The rate of Wallerian degeneration in cultured neurons from wild type and C57BL/WldS mice depends on time in culture and may be extended in the presence of elevated K+ levels. Eur J Neurosci (1995) 1.07
Prevention of motor nerve sprouting in botulinum toxin poisoned mouse soleus muscles by direct stimulation of the muscle [proceedings]. J Physiol (1977) 1.06
Stimuli to intramuscular nerve growth. Brain Res (1978) 1.06
STANDARDIZATION OF PUBLIC HEALTH TRAINING: Report of the Committee of Sixteen. Am J Public Health (N Y) (1921) 1.06
Localization of the achondroplasia gene to the distal 2.5 Mb of human chromosome 4p. Hum Mol Genet (1994) 1.05
Report of the Committee on School Health Program. Am J Public Health (N Y) (1922) 1.04
Laser-Doppler measurements and electrocochleography during ischemia of the guinea pig cochlea: implications for hearing preservation in acoustic neuroma surgery. Ann Otol Rhinol Laryngol (1993) 1.04
The responses of frog muscle spindles and fast and slow muscle fibres to a variety of mechanical inputs. J Physiol (1971) 1.03
Mesenteric vein thrombosis. Four cases and review of the literature. Dig Dis (1997) 1.03
Visuospatial impairment in Parkinson's disease. Neurology (1991) 1.02
Detection of urethral incompetence in women using the fluid-bridge test. Br J Urol (1980) 1.01
Signaling between the extracellular matrix and the cytoskeleton: tyrosine phosphorylation and focal adhesion assembly. Cold Spring Harb Symp Quant Biol (1992) 1.01
Fusimotor stimulation and the dynamic sensitivity of the secondary ending of the muscle spindle. J Physiol (1967) 1.01
Comparison of matrix metalloproteinase expression during Wallerian degeneration in the central and peripheral nervous systems. Neuroscience (2002) 1.00
Central trajectories of type II spiral ganglion cells from various cochlear regions in mice. Hear Res (1994) 1.00
Potential use of ultrasound in place of X-ray fluoroscopy in urodynamics. Br J Urol (1985) 0.99
The C3b/C4b receptor is recognized by the Knops, McCoy, Swain-langley, and York blood group antisera. J Exp Med (1991) 0.98
The alpha 6A beta 1 and alpha 6B beta 1 integrin variants signal differences in the tyrosine phosphorylation of paxillin and other proteins. J Biol Chem (1995) 0.97
A comparison of the spindles in two different muscles of the frog. J Physiol (1971) 0.97
Quantitative studies on the slowly adapting stretch receptor of the crayfish. Kybernetik (1966) 0.97
Gastrointestinal pseudo-obstruction due to pheochromocytoma. Am J Gastroenterol (1983) 0.97
Postsynaptic transmission block can cause terminal sprouting of a motor nerve. Science (1980) 0.97
beta-Cannabispiranol: a new non-cannabinoid phenol from Cannabis sativa L. Experientia (1977) 0.96
Restoration of focal multiple innervation in rat muscles by transmission block during a critical stage of development. J Physiol (1981) 0.96
A diphtheria outbreak in Chicago. IMJ Ill Med J (1970) 0.96
Role of macrophages in peripheral nerve degeneration and repair. Bioessays (1992) 0.95
Nerve growth in botulinum toxin poisoned muscles. Neuroscience (1981) 0.95