Published in J Cell Biol on March 06, 2000
Paxillin comes of age. J Cell Sci (2008) 3.57
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation. J Cell Biol (2010) 3.56
Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis. J Cell Biol (2005) 2.75
Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions. J Cell Sci (2009) 2.13
The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL). J Cell Biol (2001) 2.10
Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion. J Cell Biol (2004) 2.02
Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin. Mol Cell Biol (2004) 1.88
Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility. J Cell Biol (2004) 1.83
Crk and CrkL adaptor proteins: networks for physiological and pathological signaling. Cell Commun Signal (2009) 1.79
Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration. J Cell Biol (2002) 1.78
Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway. Mol Biol Cell (2002) 1.72
Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness. Mol Biol Cell (2005) 1.69
Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. J Clin Invest (2005) 1.61
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Mol Biol Cell (2011) 1.54
Paxillin alpha and Crk-associated substrate exert opposing effects on cell migration and contact inhibition of growth through tyrosine phosphorylation. Proc Natl Acad Sci U S A (2000) 1.46
Regulation of focal adhesion kinase by a novel protein inhibitor FIP200. Mol Biol Cell (2002) 1.46
Paxillin phosphorylation controls invadopodia/podosomes spatiotemporal organization. Mol Biol Cell (2007) 1.39
Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions. Mol Biol Cell (2002) 1.34
Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells. J Cell Biol (2001) 1.30
FAK engages multiple pathways to maintain survival of fibroblasts and epithelia: differential roles for paxillin and p130Cas. J Cell Sci (2009) 1.29
Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected]. Proc Natl Acad Sci U S A (2010) 1.27
Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Mol Cell Biol (2009) 1.26
Glycogen synthase kinase 3- and extracellular signal-regulated kinase-dependent phosphorylation of paxillin regulates cytoskeletal rearrangement. Mol Cell Biol (2006) 1.26
Calpain-mediated proteolysis of paxillin negatively regulates focal adhesion dynamics and cell migration. J Biol Chem (2011) 1.23
Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions. Biophys J (2011) 1.19
Crk associates with a multimolecular Paxillin/GIT2/beta-PIX complex and promotes Rac-dependent relocalization of Paxillin to focal contacts. Mol Biol Cell (2003) 1.16
Expression of non-phosphorylatable paxillin mutants in canine tracheal smooth muscle inhibits tension development. J Physiol (2003) 1.15
Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinase. Mol Cell Biol (2001) 1.15
The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin. Am J Pathol (2010) 1.13
Adhesion dynamics at a glance. J Cell Sci (2011) 1.13
Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo. J Biol Chem (2012) 1.10
Regulation by P2X7: epithelial migration and stromal organization in the cornea. Invest Ophthalmol Vis Sci (2008) 1.08
Reorganization of the integrin alpha2 subunit controls cell adhesion and cancer cell invasion in prostate cancer. Int J Oncol (2009) 1.05
PTTG induces EMT through integrin αVβ3-focal adhesion kinase signaling in lung cancer cells. Oncogene (2011) 1.03
RACK1 regulates Src activity and modulates paxillin dynamics during cell migration. Exp Cell Res (2007) 1.03
The focal adhesion protein paxillin regulates contraction in canine tracheal smooth muscle. J Physiol (2002) 1.03
Brk/PTK6 signaling in normal and cancer cell models. Curr Opin Pharmacol (2010) 1.02
Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesis. J Biol Chem (2009) 1.02
The small GTPase RhoA regulates the contraction of smooth muscle tissues by catalyzing the assembly of cytoskeletal signaling complexes at membrane adhesion sites. J Biol Chem (2012) 1.01
Multiple stimuli induce tyrosine phosphorylation of the Crk-binding sites of paxillin. Biochem J (2001) 1.01
TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118. Oncogene (2006) 0.98
Phosphorylation of a conserved integrin alpha 3 QPSXXE motif regulates signaling, motility, and cytoskeletal engagement. Mol Biol Cell (2001) 0.98
Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression. Br J Cancer (2008) 0.98
Estrogen stimulation of cell migration involves multiple signaling pathway interactions. Endocrinology (2010) 0.96
Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling. Mol Biol Cell (2007) 0.95
LIM and SH3 protein-1 modulates CXCR2-mediated cell migration. PLoS One (2010) 0.94
Neutrophil transmigration, focal adhesion kinase and endothelial barrier function. Microvasc Res (2011) 0.94
Serine phosphorylation regulates paxillin turnover during cell migration. Cell Commun Signal (2006) 0.91
A novel muscle LIM-only protein is generated from the paxillin gene locus in Drosophila. EMBO Rep (2001) 0.90
Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1. Cell Mol Life Sci (2008) 0.90
Reduced paxillin expression contributes to the antimetastatic effect of 4-hydroxycoumarin on B16-F10 melanoma cells. Cancer Cell Int (2008) 0.86
TNF-receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion. Br J Cancer (2013) 0.86
HER2 carboxyl-terminal fragments regulate cell migration and cortactin phosphorylation. J Biol Chem (2009) 0.85
Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin. J Exp Clin Cancer Res (2012) 0.84
Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins. BMC Neurosci (2007) 0.84
Stochastic Dynamics of Membrane Protrusion Mediated by the DOCK180/Rac Pathway in Migrating Cells. Cell Mol Bioeng (2010) 0.84
Tyrosyl phosphorylated serine-threonine kinase PAK1 is a novel regulator of prolactin-dependent breast cancer cell motility and invasion. Adv Exp Med Biol (2015) 0.83
Protein phosphatase-2A regulates protein tyrosine phosphatase activity in Lewis lung carcinoma tumor variants. Clin Exp Metastasis (2003) 0.83
Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution. World J Gastroenterol (2011) 0.83
A novel role for RhoA GTPase in the regulation of airway smooth muscle contraction. Can J Physiol Pharmacol (2014) 0.83
Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin. Sci Rep (2016) 0.82
Paxillin contracts the osteoclast cytoskeleton. J Bone Miner Res (2012) 0.81
c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury. Am J Physiol Lung Cell Mol Physiol (2015) 0.80
Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration. Sci Rep (2015) 0.79
Collagen IV regulates Caco-2 cell spreading and p130Cas phosphorylation by FAK-dependent and FAK-independent pathways. Biol Chem (2008) 0.78
A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation. PLoS One (2013) 0.78
Establishment of two new human bladder carcinoma cell lines, CAL 29 and CAL 185. Comparative study of cell scattering and epithelial to mesenchyme transition induced by growth factors. Br J Cancer (2001) 0.78
Cross-Phosphorylation and Interaction between Src/FAK and MAPKAP5/PRAK in Early Focal Adhesions Controls Cell Motility. J Cancer Biol Res (2014) 0.78
Paxillin regulates vascular endothelial growth factor A-induced in vitro angiogenesis of human umbilical vein endothelial cells. Mol Med Rep (2014) 0.77
Paxillin phosphorylation and complexing with Erk and FAK are regulated by PLD activity in MDA-MB-231 cells. Cell Signal (2012) 0.77
A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells. J Cell Sci (2017) 0.75
Post-translational modification-regulated leukocyte adhesion and migration. Oncotarget (2016) 0.75
Prolactin-induced PAK1 tyrosyl phosphorylation promotes FAK dephosphorylation, breast cancer cell motility, invasion and metastasis. BMC Cell Biol (2016) 0.75
Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer. Cancer Lett (2014) 0.75
Integrins: versatility, modulation, and signaling in cell adhesion. Cell (1992) 34.06
Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell (1996) 14.75
SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science (1991) 12.93
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice. Nature (1995) 11.06
Integrins and signal transduction pathways: the road taken. Science (1995) 10.71
Focal adhesions, contractility, and signaling. Annu Rev Cell Dev Biol (1996) 9.95
An overview of epithelio-mesenchymal transformation. Acta Anat (Basel) (1995) 9.18
Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J Cell Biol (1992) 7.97
Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science (1995) 6.45
Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase. J Cell Biol (1998) 4.91
Paxillin: a new vinculin-binding protein present in focal adhesions. J Cell Biol (1990) 4.75
Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K. Nature (1997) 4.66
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration. J Cell Biol (1998) 4.22
Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton. J Cell Biol (1989) 4.20
Bidirectional signaling between the cytoskeleton and integrins. Curr Opin Cell Biol (1999) 4.13
pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol Cell Biol (1995) 3.85
Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation. Mol Biol Cell (1996) 3.60
Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn. J Cell Sci (1996) 3.52
The molecular architecture of focal adhesions. Annu Rev Cell Dev Biol (1995) 3.41
Rho GTPases. J Biol Chem (1998) 3.35
Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling. J Cell Biol (1999) 3.34
Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases. Curr Biol (1995) 3.12
Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration. J Cell Biol (1998) 2.97
Integrins, oncogenes, and anchorage independence. J Cell Biol (1997) 2.86
Activation of Rac1 by a Crk SH3-binding protein, DOCK180. Genes Dev (1998) 2.82
Integrin signaling: specificity and control of cell survival and cell cycle progression. Curr Opin Cell Biol (1997) 2.79
Signaling through focal adhesion kinase. Bioessays (1997) 2.77
Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion. J Biol Chem (1998) 2.67
Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding. J Cell Biol (1996) 2.63
Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity. J Biol Chem (1998) 2.50
Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts. Mol Cell Biol (1993) 2.47
Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase. J Biol Chem (1995) 2.44
DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol Cell Biol (1996) 2.44
Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: identification of a vinculin and pp125Fak-binding region. J Cell Sci (1994) 2.43
Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs. J Biol Chem (1995) 2.25
Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src. Proc Natl Acad Sci U S A (1994) 2.24
Detection of Src homology 3-binding proteins, including paxillin, in normal and v-Src-transformed Balb/c 3T3 cells. J Biol Chem (1993) 2.11
Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts. J Cell Biol (1999) 2.00
The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton. Proc Natl Acad Sci U S A (1997) 2.00
Platelet-derived growth factor modulation of focal adhesion kinase (p125FAK) and paxillin tyrosine phosphorylation in Swiss 3T3 cells. Bell-shaped dose response and cross-talk with bombesin. J Biol Chem (1994) 1.94
CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells. Mol Cell Biol (1994) 1.92
Epithelial-mesenchymal transitions in cancer progression. Acta Anat (Basel) (1996) 1.84
Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex. J Biol Chem (1998) 1.72
Association of Bovine Papillomavirus Type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif. Oncogene (1998) 1.69
Rearrangements of desmosomal and cytoskeletal proteins during the transition from epithelial to fibroblastoid organization in cultured rat bladder carcinoma cells. J Cell Biol (1989) 1.65
Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells. J Biol Chem (1993) 1.61
Transformation by Rho exchange factor oncogenes is mediated by activation of an integrin-dependent pathway. EMBO J (1996) 1.56
Paxillin. Int J Biochem Cell Biol (1998) 1.55
Src and Ras are involved in separate pathways in epithelial cell scattering. EMBO J (1997) 1.53
Integrins and GTPases in tumour cell growth, motility and invasion. Trends Cell Biol (1998) 1.52
The riddle of morphogenesis: a question of solution chemistry or molecular cell engineering? Cell (1993) 1.49
Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin. Mol Biol Cell (1998) 1.39
Integrins regulate the association and phosphorylation of paxillin by c-Abl. J Biol Chem (1998) 1.37
pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line. J Cell Biol (1995) 1.37
The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells. J Biol Chem (1996) 1.37
Integrin alphavbeta3 mediates chemotactic and haptotactic motility in human melanoma cells through different signaling pathways. J Biol Chem (1996) 1.34
Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin. Biochem J (1997) 1.29
The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase. J Biol Chem (1997) 1.27
Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18. Oncogene (1997) 1.22
Structural requirement of CRK SH2 region for binding to phosphotyrosine-containing proteins. Evidence from reactivity to monoclonal antibodies. J Biol Chem (1993) 1.20
Scatter factor/hepatocyte growth factor (SF/HGF) induces emigration of myogenic cells at interlimb level in vivo. Dev Biol (1996) 1.10
Collagen-mediated dispersion of NBT-II rat bladder carcinoma cells. Cancer Res (1990) 1.09
Alpha 2 beta 1 integrin is required for the collagen and FGF-1 induced cell dispersion in a rat bladder carcinoma cell line. Cell Adhes Commun (1996) 1.09
Model systems of epithelium-mesenchyme transitions. Acta Anat (Basel) (1996) 1.08
CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells. J Biol Chem (1995) 1.06
The functional role of CrkII in actin cytoskeleton organization and mitogenesis. J Biol Chem (1999) 1.06
Networks of interaction of p120cbl and p130cas with Crk and Grb2 adaptor proteins. Oncogene (1996) 1.04
Bombesin stimulates the motility of human prostate-carcinoma cells through tyrosine phosphorylation of focal adhesion kinase and of integrin-associated proteins. Int J Cancer (1997) 1.04
Tissue culture of urinary bladder tumor induced in a rat by N-butyl-N-(-4-hydroxybutyl)nitrosamine: establishment of cell line, Nara Bladder Tumor II. J Natl Cancer Inst (1971) 1.03
Alternative patterns of mitogenesis and cell scattering induced by acidic FGF as a function of cell density in a rat bladder carcinoma cell line. Cell Regul (1990) 1.02
Angiotensin II stimulation of rapid paxillin tyrosine phosphorylation correlates with the formation of focal adhesions in rat aortic smooth muscle cells. J Cell Sci (1995) 0.99
Epithelio-mesenchymal transformation during formation of the mesoderm in the mammalian embryo. Acta Anat (Basel) (1995) 0.96
BCR/ABL-induced leukemogenesis causes phosphorylation of Hef1 and its association with Crkl. J Biol Chem (1997) 0.92
Characterization of the signaling pathways regulating alpha2beta1 integrin-mediated events by a pharmacological approach. Cell Adhes Commun (1999) 0.87
Possible v-Crk-induced transformation through activation of Src kinases. J Biol Chem (1995) 0.83
Nerve growth factor triggers microfilament assembly and paxillin phosphorylation in human B lymphocytes. J Exp Med (1995) 0.83
Cytokine control of cell motility: modulation and mediation by the extracellular matrix. Prog Growth Factor Res (1994) 0.82
Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J Cell Biol (1992) 7.97
Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins. Proc Natl Acad Sci U S A (1991) 5.76
Adhesion among neural cells of the chick embryo. I. An immunological assay for molecules involved in cell-cell binding. J Biol Chem (1977) 5.61
Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. Nat Genet (1999) 5.29
Adhesion among neural cells of the chick embryo. II. Purification and characterization of a cell adhesion molecule from neural retina. J Biol Chem (1977) 4.15
Cell adhesion molecules in early chicken embryogenesis. Proc Natl Acad Sci U S A (1982) 4.01
The specificity of deoxyribonucleases and their use in nucleotide sequence studies. Nat New Biol (1973) 3.56
The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J Cell Biol (1997) 3.52
Induction and regulation of epithelial-mesenchymal transitions. Biochem Pharmacol (2000) 3.34
Mechanisms of adhesion among cells from neural tissues of the chick embryo. Proc Natl Acad Sci U S A (1976) 3.25
Early epochal maps of two different cell adhesion molecules. Proc Natl Acad Sci U S A (1983) 3.06
Ontogenetic expression of cell adhesion molecules: L-CAM is found in epithelia derived from the three primary germ layers. Dev Biol (1984) 2.81
Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development (2001) 2.79
Adhesion among neural cells of the chick embryo. III. Relationship of the surface molecule CAM to cell adhesion and the development of histotypic patterns. J Cell Biol (1978) 2.63
Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding. J Cell Biol (1996) 2.63
Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors. Am J Pathol (2001) 2.55
Antibodies to a neural cell adhesion molecule disrupt histogenesis in cultured chick retinae. Nature (1980) 2.54
Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase. J Biol Chem (1995) 2.44
Chromosomes in Ewing's sarcoma. I. An evaluation of 85 cases of remarkable consistency of t(11;22)(q24;q12). Cancer Genet Cytogenet (1988) 2.42
Fibronectin receptor exhibits high lateral mobility in embryonic locomoting cells but is immobile in focal contacts and fibrillar streaks in stationary cells. J Cell Biol (1988) 2.38
Adhesion molecules during somitogenesis in the avian embryo. J Cell Biol (1987) 2.20
An analysis of the bovine genome by Cs2SO4-Ag density gradient centrifugation. J Mol Biol (1973) 2.17
Detection of Src homology 3-binding proteins, including paxillin, in normal and v-Src-transformed Balb/c 3T3 cells. J Biol Chem (1993) 2.11
The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL). J Cell Biol (2001) 2.10
Public Health Degrees Granted in 1934 : Report of the Committee on Professional Education. Am J Public Health Nations Health (1935) 2.03
IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition. Oncogene (2001) 2.03
Fibronectin in early avian embryos: synthesis and distribution along the migration pathways of neural crest cells. Cell Tissue Res (1980) 2.02
Expression of smooth muscle-specific proteins in myoepithelium and stromal myofibroblasts of normal and malignant human breast tissue. Proc Natl Acad Sci U S A (1993) 2.01
Site-restricted expression of cytotactin during development of the chicken embryo. J Cell Biol (1986) 1.95
Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion. J Cell Biol (2000) 1.95
Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis. Mech Dev (2001) 1.94
An analysis of eukaryotic genomes by density gradient centrifugation. J Mol Biol (1976) 1.89
Neural crest cell migration: requirements for exogenous fibronectin and high cell density. J Cell Biol (1983) 1.84
An approach to the organization of eukaryotic genomes at a macromolecular level. J Mol Biol (1976) 1.83
Effectiveness of Radio in Health Education. Am J Public Health Nations Health (1935) 1.82
Cell adhesion and migration in the early vertebrate embryo: location and possible role of the putative fibronectin receptor complex. J Cell Biol (1986) 1.78
Pathways and mechanisms of avian trunk neural crest cell migration and localization. Dev Biol (1982) 1.77
Characterisation of the paxillin-binding site and the C-terminal focal adhesion targeting sequence in vinculin. J Cell Sci (1994) 1.76
Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions. J Biol Chem (2001) 1.73
Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin. J Cell Sci (1999) 1.72
Focal adhesions: structure and dynamics. Biol Cell (2000) 1.71
Identical reactivity of monoclonal antibodies HNK-1 and NC-1: conservation in vertebrates on cells derived from the neural primordium and on some leukocytes. Cell Differ (1984) 1.70
Association of Bovine Papillomavirus Type 1 E6 oncoprotein with the focal adhesion protein paxillin through a conserved protein interaction motif. Oncogene (1998) 1.69
An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene. Mol Cell Biol (1994) 1.68
Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells. Mol Biol Cell (1994) 1.67
Rearrangements of desmosomal and cytoskeletal proteins during the transition from epithelial to fibroblastoid organization in cultured rat bladder carcinoma cells. J Cell Biol (1989) 1.65
Perturbation of beta1-integrin function alters the development of murine mammary gland. EMBO J (1998) 1.64
Attachment, spreading and locomotion of avian neural crest cells are mediated by multiple adhesion sites on fibronectin molecules. EMBO J (1988) 1.62
Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells. J Biol Chem (1993) 1.61
High incidence of anticytomegalovirus drug resistance among D+R- kidney transplant recipients receiving preemptive therapy. Am J Transplant (2011) 1.60
Initial appearance and regional distribution of the neuron-glia cell adhesion molecule in the chick embryo. J Cell Biol (1985) 1.54
Src and Ras are involved in separate pathways in epithelial cell scattering. EMBO J (1997) 1.53
Paxillin LD motifs may define a new family of protein recognition domains. Nat Struct Biol (1998) 1.52
The nervous system specific protein D2 is involved in adhesion among neurites from cultured rat ganglia. FEBS Lett (1980) 1.52
Constituents of Cannabis sativa L. XVII. A review of the natural constituents. J Nat Prod (1980) 1.51
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530). Cell Death Dis (2013) 1.49
Cloning and characterization of three Xenopus slug promoters reveal direct regulation by Lef/beta-catenin signaling. J Biol Chem (2001) 1.47
Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells. Mol Biol Cell (1994) 1.46
Appearance and distribution of fibronectin during chick embryo gastrulation and neurulation. Dev Biol (1982) 1.45
Cloning and expression pattern of a mouse homologue of drosophila sprouty in the mouse embryo. Mech Dev (1999) 1.40
Malden Studies on Health Education and Growth. Am J Public Health Nations Health (1928) 1.40
PUBLIC HEALTH TRAINING. Am J Public Health (N Y) (1926) 1.39
Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin. Mol Biol Cell (1998) 1.39
Neural crest cell locomotion induced by antibodies to beta 1 integrins. A tool for studying the roles of substratum molecular avidity and density in migration. J Cell Sci (1991) 1.38
Quantitative changes in integrin and focal adhesion signaling regulate myoblast cell cycle withdrawal. J Cell Biol (1999) 1.38
HEALTH TEACHING AND THE SCHOOL HEALTH PROGRAM. Am J Public Health (N Y) (1921) 1.38
pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line. J Cell Biol (1995) 1.37
Distribution of fibronectin in the early phase of avian cephalic neural crest cell migration. Dev Biol (1982) 1.37
Acidic fibroblast growth factor is a modulator of epithelial plasticity in a rat bladder carcinoma cell line. Proc Natl Acad Sci U S A (1990) 1.37
Requirement for fibroblast growth factor 10 or fibroblast growth factor receptor 2-IIIb signaling for cecal development in mouse. Dev Biol (2004) 1.36
Functional studies of the domains of talin. J Cell Biol (1990) 1.35
Transient effect of epidermal growth factor on the motility of an immortalized mammary epithelial cell line. J Cell Sci (1993) 1.35
Fibroblast growth factor-2. Int J Biochem Cell Biol (2000) 1.34
Structure and modulation of neural cell adhesion molecules in early and late embryogenesis. Cold Spring Harb Symp Quant Biol (1983) 1.32
Cell migration in the vertebrate embryo: role of cell adhesion and tissue environment in pattern formation. Annu Rev Cell Biol (1985) 1.31
Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin. Biochem J (1997) 1.29
How To Improve Dental Conditions in the United States. Am J Public Health Nations Health (1939) 1.28
Overexpression of nucleoside diphosphate kinase (Nm23) in solid tumours. Eur J Cancer (1991) 1.27
Tumour suppressive properties of fibroblast growth factor receptor 2-IIIb in human bladder cancer. Oncogene (1999) 1.27
A new hepadnavirus endemic in arctic ground squirrels in Alaska. J Virol (1996) 1.26
Frequent loss of heterozygosity on chromosome 10q in muscle-invasive transitional cell carcinomas of the bladder. Oncogene (1997) 1.25
Cadherin 11 expression marks the mesenchymal phenotype: towards new functions for cadherins? Cell Adhes Commun (1995) 1.25
Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity. Oncogene (1994) 1.24
Homing of hemopoietic precursor cells to the embryonic thymus: characterization of an invasive mechanism induced by chemotactic peptides. J Cell Biol (1986) 1.24
Prevention of gastrulation but not neurulation by antibodies to fibronectin in amphibian embryos. Nature (1984) 1.19
Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton. J Biol Chem (2000) 1.19
Associations of obesity with triglycerides and C-reactive protein are attenuated in adults with high red blood cell eicosapentaenoic and docosahexaenoic acids. Eur J Clin Nutr (2011) 1.19
Reversible transition towards a fibroblastic phenotype in a rat carcinoma cell line. Int J Cancer Suppl (1989) 1.17
A cell surface marker for neural crest and placodal cells: further evolution in peripheral and central nervous system. Dev Biol (1984) 1.16
Expression of transfected transforming growth factor alpha induces a motile fibroblast-like phenotype with extracellular matrix-degrading potential in a rat bladder carcinoma cell line. Cell Regul (1990) 1.16
Xenopus cadherin-11 is expressed in different populations of migrating neural crest cells. Mech Dev (1998) 1.16
Decreased expression of keratinocyte growth factor receptor in a subset of human transitional cell bladder carcinomas. Oncogene (1997) 1.16