PubRank

G Chinnadurai

Author PubWeight™ 127.49‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell 1994 3.86
2 A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions. EMBO J 1995 3.70
3 Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation. Proc Natl Acad Sci U S A 1995 3.28
4 Multiple functional domains of Tat, the trans-activator of HIV-1, defined by mutational analysis. Nucleic Acids Res 1989 2.72
5 A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis. EMBO J 1993 2.58
6 Physical mapping of a large-plaque mutation of adenovirus type 2. J Virol 1979 2.50
7 Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 Tat protein. Proc Natl Acad Sci U S A 1991 2.17
8 BH3-only proteins in apoptosis and beyond: an overview. Oncogene 2008 2.13
9 Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator. Virology 1996 2.12
10 Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif. J Biol Chem 1998 2.06
11 Adenovirus 2 Ip+ locus codes for a 19 kd tumor antigen that plays an essential role in cell transformation. Cell 1983 2.01
12 Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence. J Biol Chem 1998 1.81
13 Distinct cis-acting regions in U3 regulate trans-activation of the human spumaretrovirus long terminal repeat by the viral bel1 gene product. Nucleic Acids Res 1991 1.63
14 Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage. J Biol Chem 1999 1.57
15 Role of the PLDLS-binding cleft region of CtBP1 in recruitment of core and auxiliary components of the corepressor complex. Mol Cell Biol 2007 1.49
16 Mutants in a conserved region near the carboxy-terminus of HIV-1 Rev identify functionally important residues and exhibit a dominant negative phenotype. Virology 1990 1.48
17 19-kDa tumor antigen coded by early region E1b of adenovirus 2 is required for efficient synthesis and for protection of viral DNA. J Biol Chem 1984 1.47
18 A unique pattern of integrated viral genes in hamster cells transformed by highly oncogenic human adenovirus 12. Cell 1976 1.45
19 Epstein-Barr virus BHRF1 protein protects against cell death induced by DNA-damaging agents and heterologous viral infection. Virology 1994 1.42
20 An N-terminal region of adenovirus E1a essential for cell transformation and induction of an epithelial cell growth factor. Oncogene 1988 1.41
21 Enhanced infectivity of adenovirus type 2 DNA and a DNA-protein complex. J Virol 1978 1.40
22 Enhanced ras oncogene mediated cell transformation and tumorigenesis by adenovirus 2 mutants lacking the C-terminal region of E1a protein. Oncogene 1989 1.40
23 Nicotinamide adenine dinucleotide stimulates oligomerization, interaction with adenovirus E1A and an intrinsic dehydrogenase activity of CtBP. FEBS Lett 2003 1.38
24 The CtBP binding domain in the adenovirus E1A protein controls CR1-dependent transactivation. Nucleic Acids Res 1996 1.33
25 Adenovirus transforming 19-kD T antigen has an enhancer-dependent trans-activation function and relieves enhancer repression mediated by viral and cellular genes. Genes Dev 1987 1.30
26 Evidence that a second tumor antigen coded by adenovirus early gene region E1a is required for efficient cell transformation. Proc Natl Acad Sci U S A 1985 1.27
27 Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral Tat protein and cellular transcription factor Sp1. J Virol 1992 1.25
28 Heterologous basic domain substitutions in the HIV-1 Tat protein reveal an arginine-rich motif required for transactivation. EMBO J 1991 1.24
29 Relationship between the transforming and transcriptional regulatory functions of adenovirus 2 E1a oncogene. Virology 1987 1.24
30 Functional dissection of the human spumaretrovirus transactivator identifies distinct classes of dominant-negative mutants. J Virol 1993 1.24
31 p53-independent apoptotic and necrotic cell deaths induced by adenovirus infection: suppression by E1B 19K and Bcl-2 proteins. Cell Growth Differ 1995 1.23
32 BH3-only protein BIK induces caspase-independent cell death with autophagic features in Bcl-2 null cells. Oncogene 2007 1.22
33 Pre-early polypeptides of bacteriophages T5 and BF23. J Virol 1977 1.21
34 Functional dissection of Bfl-1, a Bcl-2 homolog: anti-apoptosis, oncogene-cooperation and cell proliferation activities. Oncogene 1998 1.17
35 Acetylation by p300 regulates nuclear localization and function of the transcriptional corepressor CtBP2. J Biol Chem 2005 1.17
36 Structural determinants present in the C-terminal binding protein binding site of adenovirus early region 1A proteins. J Biol Chem 1998 1.17
37 Association of class I histone deacetylases with transcriptional corepressor CtBP. FEBS Lett 2003 1.16
38 Critical requirement of BAX for manifestation of apoptosis induced by multiple stimuli in human epithelial cancer cells. Cancer Res 2002 1.16
39 Functional substitution of the basic domain of the HIV-1 trans-activator, Tat, with the basic domain of the functionally heterologous Rev. Virology 1990 1.15
40 Genetic identification of adenovirus type 5 genes that influence viral spread. J Virol 2006 1.14
41 Functional domains of the HIV-1 rev gene required for trans-regulation and subcellular localization. Virology 1990 1.13
42 Modulation of mitochondrial Ca(2+) homeostasis by Bcl-2. J Biol Chem 1999 1.12
43 bfl-1, a bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity. Cancer Res 1996 1.11
44 mRNA from the transforming segment of the adenovirus 2 genome in productively infected and transformed cells. J Virol 1976 1.11
45 Unmasking of a proliferation-restraining activity of the anti-apoptosis protein EBV BHRF1. Oncogene 1996 1.10
46 BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3. Cancer Res 1999 1.09
47 Phosphorylation of the pro-apoptotic protein BIK: mapping of phosphorylation sites and effect on apoptosis. J Biol Chem 2000 1.08
48 Requirement of a phage-induced 5'-exonuclease for the expression of late genes of bacteriophage T5. Proc Natl Acad Sci U S A 1973 1.08
49 Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells. J Immunol 2001 1.03
50 The pro-apoptotic protein, Bik, exhibits potent antitumor activity that is dependent on its BH3 domain. Mol Cancer Ther 2001 1.01
51 Adenovirus cyt+ locus, which controls cell transformation and tumorigenicity, is an allele of lp+ locus, which codes for a 19-kilodalton tumor antigen. J Virol 1984 1.01
52 Deletion of a nonconserved region of Bcl-2 confers a novel gain of function: suppression of apoptosis with concomitant cell proliferation. Cancer Res 1996 0.99
53 Dual role of gene D5 in the development of bacteriophage T5. Nature 1974 0.98
54 The carboxy-terminal transcription enhancement region of the human spumaretrovirus transactivator contains discrete determinants of the activator function. J Virol 1993 0.97
55 Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors. J Virol 2010 0.97
56 Functional dissection of the pro-apoptotic protein Bik. Heterodimerization with anti-apoptosis proteins is insufficient for induction of cell death. J Biol Chem 1997 0.97
57 Activation of the adenovirus 2 protein IX promoter by DNA replication in a transient expression assay. Nucleic Acids Res 1987 0.97
58 Hinf family: a novel repeated DNA family of the human genome. Nature 1983 0.96
59 Transforming genes among three different oncogenic subgroups of human adenoviruses have similar replicative functions. J Virol 1981 0.95
60 Silencing of human immunodeficiency virus long terminal repeat expression by an adenovirus E1a mutant. Proc Natl Acad Sci U S A 1990 0.95
61 Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells. Oncogene 2006 0.95
62 Regulation of apoptosis by a Caenorhabditis elegans BNIP3 homolog. Oncogene 1998 0.94
63 Regulation of expression of late genes of bacteriophage T5. J Virol 1974 0.94
64 Immortalization of rat embryo fibroblasts by an adenovirus 2 mutant expressing a single functional E1a protein. J Virol 1985 0.94
65 Changes in C-terminal binding protein 2 (CtBP2) corepressor complex induced by E1A and modulation of E1A transcriptional activity by CtBP2. J Biol Chem 2006 0.94
66 Evidence for involvement of BH3-only proapoptotic members in adenovirus-induced apoptosis. J Virol 2007 0.93
67 Structural analysis of the human pro-apoptotic gene Bik: chromosomal localization, genomic organization and localization of promoter sequences. Gene 2000 0.93
68 Functional substitution identifies a cell survival promoting domain common to adenovirus E1B 19 kDa and Bcl-2 proteins. Oncogene 1995 0.92
69 Mutational analysis of the transforming and apoptosis suppression activities of the adenovirus E1B 175R protein. Gene 1993 0.92
70 Functional comparison of the basic domains of the Tat proteins of human immunodeficiency virus types 1 and 2 in trans activation. J Virol 1992 0.92
71 Mitochondrial localization of p53 during adenovirus infection and regulation of its activity by E1B-19K. Oncogene 2005 0.90
72 A potent cell death activity associated with transient high level expression of BCL-2. J Biol Chem 1998 0.90
73 Selective induction of toxicity to human cells expressing human immunodeficiency virus type 1 Tat by a conditionally cytotoxic adenovirus vector. Proc Natl Acad Sci U S A 1990 0.90
74 PLDLS-dependent interaction of E1A with CtBP: regulation of CtBP nuclear localization and transcriptional functions. Oncogene 2007 0.90
75 Interaction of ZEB and histone deacetylase with the PLDLS-binding cleft region of monomeric C-terminal binding protein 2. BMC Mol Biol 2009 0.89
76 Requirement of BAX for efficient adenovirus-induced apoptosis. J Virol 2002 0.88
77 Method for introducing site-specific mutations into adenovirus 2 genome: construction of a small deletion mutant in VA-RNAI gene. Proc Natl Acad Sci U S A 1981 0.87
78 A nonessential glycoprotein is coded by early region E3 of adenovirus type 7. Virology 1981 0.87
79 Pro-apoptotic activity of transiently expressed BCL-2 occurs independent of BAX and BAK. J Cell Biochem 2003 0.85
80 Requirement of the C-terminal region of adenovirus E1a for cell transformation in cooperation with E1b. Oncogene 1991 0.85
81 Separation of immortalization and T24-ras oncogene cooperative functions of adenovirus E1a. Oncogene 1988 0.85
82 Identification of early proteins induced by highly oncogenic human adenovirus 12 during lytic infection and in hamster tumors. Biochem Biophys Res Commun 1977 0.85
83 BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition? Mol Cancer Res 2009 0.83
84 Separation of the functions controlled by adenovirus 2 lp+ locus. Virology 1986 0.83
85 Adenovirus L-E1A activates transcription through mediator complex-dependent recruitment of the super elongation complex. J Virol 2013 0.83
86 Functional similarity between adenovirus e1b 19k gene and bcl2 oncogene - mutant complementation and suppression of cell-death induced by DNA-damaging agents. Int J Oncol 1993 0.82
87 Activation of a heterologous promoter by human immunodeficiency virus type 1 Tat requires Sp1 and is distinct from the mode of activation by acidic transcriptional activators. J Virol 1993 0.81
88 Cell type dependent transformation by adenovirus 5 E1a proteins. Oncogene 1988 0.81
89 A nuclear kinesin-like protein interacts with and stimulates the activity of the leucine-rich nuclear export signal of the human immunodeficiency virus type 1 rev protein. J Virol 2003 0.81
90 Down-regulation of multiple cell survival proteins in head and neck cancer cells by an apoptogenic mutant of adenovirus type 5. Virology 2009 0.80
91 Functional identification of the apoptosis effector BH3 domain in cellular protein BNIP1. Oncogene 2000 0.80
92 Interaction of CtBP with adenovirus E1A suppresses immortalization of primary epithelial cells and enhances virus replication during productive infection. Virology 2013 0.80
93 The activation region of the Tat protein of human immunodeficiency virus type-1 functions in yeast. Nucleic Acids Res 1994 0.79
94 A hydrophobic region within the adenovirus E1B 19 kDa protein is necessary for the transient inhibition of NF-kappaB activated by different stimuli. J Biol Chem 1996 0.79
95 Sox9 transactivation and testicular expression of a novel human gene, KIAA0800. J Cell Biochem 2002 0.79
96 Functional similarity between adenovirus E1B 19-kDa protein and proteins encoded by Bcl-2 proto-oncogene and Epstein-Barr virus BHRF1 gene. Curr Top Microbiol Immunol 1995 0.79
97 An adenovirus 2-coded tumor antigen located on the endoplasmic reticulum and nuclear envelope is required for growth of transformed cells in Ca2+-deficient media. Mol Cell Biol 1985 0.79
98 Functional relatedness between the E1a and E1b regions of group C and group D human adenoviruses. Virus Res 1987 0.79
99 Overexpression of BH3-Only Protein BNIP3 Leads to Enhanced Tumor Growth. Genes Cancer 2010 0.78
100 A unique subgenomic species of adenovirus 2 DNA generated under high multiplicities of infection. Nucleic Acids Res 1979 0.78
101 Identification of adenovirus type 12 candidate transformation proteins by radioimmunoprecipitation with antisera to EcoRI-C-fragment transformed cells. Virology 1979 0.78
102 Incapacitating CtBP to kill cancer. Cell Cycle 2010 0.77
103 Mapping of adenovirus 5 E1A domains responsible for suppression of neu-mediated transformation via transcriptional repression of neu. Oncogene 1997 0.77
104 Efficient transformation of rat 3Y1 cells by human adenovirus type 9. Virology 1984 0.77
105 Interaction of cellular apoptosis regulating proteins with adenovirus anti-apoptosis protein E1B-19K. Methods Mol Biol 2001 0.77
106 A high-level expression vector for human cells. Gene 1992 0.76
107 Inhibition of transcriptional activation and cell proliferation activities of adenovirus E1A by the unique N-terminal domain of CtBP2. Oncogene 2008 0.76
108 Functional similarity between E6 proteins of cutaneous human papillomaviruses and the adenovirus E1A tumor-restraining module. J Virol 2013 0.75
109 Physiology of sorghum spikelets infected by Sphacelia sorghi: effect on phenolics & polyphenol oxidase. Indian J Exp Biol 1970 0.75
110 Viable variants in VA-RNA, gene of an Ad2-Ad5 recombinant. Virology 1981 0.75
111 Localization of a transcription start point within the human Hinf element. Gene 1989 0.75
112 Structure and reversion of an adenovirus type 2 mutant containing a duplication of the left end of the genome at the right end. Virology 1983 0.75
113 Loss of biological activity of bacteriophage 2C and degradation of its DNA in storage. Z Naturforsch B 1972 0.75