The role of the physical state of lipopolysaccharides in the interaction with complement. High molecular weight as prerequisite for the expression of anti-complementary activity.

PubWeight™: 1.64‹?› | Rank: Top 3%

🔗 View Article (PMID 949975)

Published in Eur J Biochem on June 01, 1976

Authors

C Galanos, O Lüderitz

Articles citing this

The effects of bacterial endotoxins on host mediation systems. A review. Am J Pathol (1978) 6.03

Bactericidal and bacteriolytic activity of serum against gram-negative bacteria. Microbiol Rev (1983) 5.73

Biological activities of Brucella abortus lipopolysaccharides. Infect Immun (1981) 2.13

New function for high density lipoproteins. Isolation and characterization of a bacterial lipopolysaccharide-high density lipoprotein complex formed in rabbit plasma. J Clin Invest (1981) 2.08

Interaction of lipopolysaccharides with plasma high-density lipoprotein in rats. Infect Immun (1980) 1.85

Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate. Infect Immun (1984) 1.59

Binding of Salmonella typhimurium lipopolysaccharides to rat high-density lipoproteins. Infect Immun (1981) 1.55

Radioimmunoassay for Gram-negative bacterial lipopolysaccharide O antigens: influence of antigen solubility. Infect Immun (1979) 1.29

Titration calorimetric studies to elucidate the specificity of the interactions of polymyxin B with lipopolysaccharides and lipid A. Biochem J (1996) 1.27

Role of lipopolysaccharide and complement in susceptibility of Haemophilus ducreyi to human serum. Infect Immun (1985) 1.27

Factors affecting complement activation by Staphylococcus aureus cell walls, their components, and mutants altered in teichoic acid. Infect Immun (1981) 1.22

Biological activities of lipopolysaccharides and lipid A from Rhodospirillaceae. Infect Immun (1977) 1.21

Lipooligosaccharides from Treponema hyodysenteriae and Treponema innocens. Infect Immun (1988) 1.08

Pseudomonas aeruginosa bacteriophage phi PLS27-lipopolysaccharide interactions. J Virol (1981) 1.06

Biological and physicochemical properties of the lipopolysaccharide of Chromatium vinosum. Infect Immun (1977) 1.05

Antibody-independent activation of the classical pathway of human serum complement by lipid A is restricted to re-chemotype lipopolysaccharide and purified lipid A. Infect Immun (1986) 0.99

Interaction of lipopolysaccharides and lipid A with complement in rats and its relation to endotoxicity. Infect Immun (1978) 0.99

Role of the physical state of Salmonella lipopolysaccharide in expression of biological and endotoxic properties. Infect Immun (1993) 0.93

Neutrophil adherence induced by lipopolysaccharide in vitro. Role of plasma component interaction with lipopolysaccharide. J Clin Invest (1992) 0.93

Inverse relationship between the susceptibility of lipopolysaccharide (lipid A)-pretreated mice to the hypothermic and lethal effect of lipopolysaccharide. Infect Immun (1978) 0.91

The distribution of lipopolysaccharide in normocomplementemic and C3-depleted rabbits and rhesus monkeys. Am J Pathol (1980) 0.90

Effects of certain cations (Fe, Zn, Mg, and Ca) on bacterial endotoxins. Infect Immun (1978) 0.81

Articles by these authors

Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science (1998) 37.15

A new method for the extraction of R lipopolysaccharides. Eur J Biochem (1969) 22.41

Immunochemistry of O and R antigens of Salmonella and related Enterobacteriaceae. Bacteriol Rev (1966) 13.42

Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc Natl Acad Sci U S A (1979) 6.77

Electrodialysis of lipopolysaccharides and their conversion to uniform salt forms. Eur J Biochem (1975) 5.29

The mitogenic effect of lipopolysaccharide on bone marrow-derived mouse lymphocytes. Lipid A as the mitogenic part of the molecule. J Exp Med (1973) 4.74

Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice. J Exp Med (1987) 4.63

Picogram-sensitive assay for endotoxin: gelation of Limulus polyphemus blood cell lysate induced by purified lipopolysaccharides and lipid A from Gram-negative bacteria. Biochim Biophys Acta (1972) 4.45

Nature and linkages of the fatty acids present in the lipid-A component of Salmonella lipopolysaccharides. Eur J Biochem (1972) 4.15

Interaction of lipopolysaccharides and lipid A with complement. Eur J Biochem (1971) 4.15

Structural investigations on the 2-keto-3-deoxyoctonate region of lipopolysaccharides. Eur J Biochem (1970) 4.14

Preparation and properties of antisera against the lipid-A component of bacterial lipopolysaccharides. Eur J Biochem (1971) 4.01

Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities. Eur J Biochem (1985) 3.76

The lipoprotein of the outer membrane of Escherichia coli: a B-lymphocyte mitogen. J Exp Med (1975) 3.55

Structural relationship of Salmonella O and R antigens. Ann N Y Acad Sci (1966) 3.54

Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect Immun (1986) 3.42

Preparation and properties of a standardized lipopolysaccharide from salmonella abortus equi (Novo-Pyrexal). Zentralbl Bakteriol Orig A (1979) 3.08

Biological activities of lipid A complexed with bovine-serum albumin. Eur J Biochem (1972) 3.04

Biochemical studies on lipopolysaccharides of Salmonella R mutants. 6. Investigations on the structure of the lipid A component. Eur J Biochem (1969) 2.93

Tumor necrosis factor alpha mediates lethal activity of killed gram-negative and gram-positive bacteria in D-galactosamine-treated mice. Infect Immun (1991) 2.34

Induction of tolerance to lipopolysaccharide (LPS)-D-galactosamine lethality by pretreatment with LPS is mediated by macrophages. Infect Immun (1988) 2.23

Differential determination of the 3-Deoxy-D-mannooctulosonic acid residues in lipopolysaccharides of Salmonella minnesota rough mutants. Eur J Biochem (1983) 2.12

Granulocyte activation by endotoxin. I. Correlation between adherence and other granulocyte functions, and role of endotoxin structure on biologic activity. J Immunol (1983) 2.06

Modification of the silver staining technique to detect lipopolysaccharide in polyacrylamide gels. J Clin Microbiol (1990) 2.02

A new gene cluster rfe concerned with the biosynthesis of Salmonella lipopolysaccharide. J Gen Microbiol (1970) 1.91

Interaction of lipopolysaccharides with plasma high-density lipoprotein in rats. Infect Immun (1980) 1.85

Lipid A: chemical structure and biological activity. J Infect Dis (1973) 1.73

Diurnal variations in the human host response to endotoxin. J Infect Dis (1996) 1.71

Chemical structure and biological activities of lipid A's from various bacterial families. Naturwissenschaften (1978) 1.69

The chemical structure of lipid A. Demonstration of amide-linked 3-acyloxyacyl residues in Salmonella minnesota Re lipopolysaccharide. Eur J Biochem (1982) 1.67

Studies on the structure of lipopolysaccharides of Salmonella minnesota and Salmonella typhimurium R strains. Biochem J (1965) 1.60

Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate. Infect Immun (1984) 1.59

Bacterial endotoxins: chemical structure, biological activity and role in septicaemia. Scand J Infect Dis Suppl (1982) 1.56

Physical state and biological activity of lipopolysaccharides. Toxicity and immunogenicity of the lipid A component. Z Immunitatsforsch Exp Klin Immunol (1975) 1.55

Time course of cellular distribution of endotoxin in liver, lungs and kidneys of rats. Br J Exp Pathol (1982) 1.54

Immunogenic properties of lipid A. Rev Infect Dis (1984) 1.51

A lipopolysaccharide-binding cell-surface protein from Salmonella minnesota. Isolation, partial characterization and occurrence in different Enterobacteriaceae. Eur J Biochem (1979) 1.49

A new class of heptose-defective mutant of Salmonella typhimurium. Eur J Biochem (1973) 1.48

Composition of lipopolysaccharides from Myxococcus fulvus and other fruiting and non-fruiting myxobacteria. Eur J Biochem (1974) 1.46

Comparative immunochemistry of lipopolysaccharides from typable and polyagglutinable Pseudomonas aeruginosa strains isolated from patients with cystic fibrosis. J Clin Microbiol (1988) 1.46

The immunochemistry of Salmonella chemotype VI O-antigens. The structure of oligosaccharides from Salmonella group G (o 13,22) lipopolysaccharides. Biochem J (1965) 1.46

Isolation, purification, and chemical analysis of the lipopolysaccharide and lipid A of Acinetobacter calcoaceticus NCTC 10305. Eur J Biochem (1982) 1.39

Pyrogenicity and immunogenicity of lipid A complexed with bovine serum albumin or human serum albumin. Infect Immun (1973) 1.38

Nontoxic lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023. J Bacteriol (1983) 1.37

Biological activities of chemically modified endotoxins. Eur J Biochem (1971) 1.36

Induction of hyperreactivity to endotoxin in mice by Coxiella burnetii. Infect Immun (1984) 1.36

Lipid A, the endotoxic center of bacterial lipopolysaccharides: relation of chemical structure to biological activity. Prog Clin Biol Res (1987) 1.35

Biochemical studies on lipopolysaccharides of Salmonella R mutants. 4. Phosphate groups linked to heptose units and their absence in some R lipopolysaccharides. Eur J Biochem (1968) 1.35

Recent results on the biochemistry of the cell wall lipopolysaccharides of Salmonella bacteria. Angew Chem Int Ed Engl (1970) 1.35

Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A. Eur J Biochem (1984) 1.33

Occurrence of 3-amino-3,6-dideoxyhexoses in Salmonella and related bacteria. J Bacteriol (1967) 1.30

Immunological priming without production of circulating bacterial antibodies conditioned by endotoxin and its lipoid A component. Nature (1966) 1.28

Macrophage factor controlling differentiation of B cells. J Immunol (1979) 1.28

Interactions of the complement system with endotoxins from a Salmonella minnesota mutant deficient in O-polysaccharide and heptose. J Immunol (1968) 1.27

[Polysaccharides of vegetative and aggregationally competent amoebae of the strain Dictyostelium discoideum. 1. In vivo degradation of bacterial lipopolysaccharides]. Eur J Biochem (1967) 1.27

Bacterial induction of beta interferon in mice is a function of the lipopolysaccharide component. Infect Immun (2000) 1.27

Phase II trial of intravenous endotoxin in patients with colorectal and non-small cell lung cancer. Eur J Cancer (1996) 1.26

Dose-dependent effects of endotoxin on human sleep. Am J Physiol Regul Integr Comp Physiol (2000) 1.26

Biochemical studies on lipopolysaccharides of Salmonella R mutants. 3. The linkage of the heptose units. Eur J Biochem (1968) 1.25

Structural investigations on the core polysaccharide of Escherichia coli 0100. Eur J Biochem (1971) 1.24

Structural studies on the heptose region of Salmonella lipopolysaccharides. Eur J Biochem (1973) 1.23

Lipid A antiserum-mediated protection against lipopolysaccharide- and lipid A-induced fever and skin necrosis. Infect Immun (1977) 1.23

Lipopolysaccharides: structural principles and biologic activities. Rev Infect Dis (1984) 1.22

Biological activities of lipopolysaccharides and lipid A from Rhodospirillaceae. Infect Immun (1977) 1.21

The occurrence of 4-amino-4-deoxy-L-arabinose as a constituent in Salmonella lipopolysaccharide preparations. Eur J Biochem (1970) 1.20

Inhibition by lipoid A of formation of antibodies against common antigen of enterobacteriaceae. Proc Soc Exp Biol Med (1965) 1.20

Gamma interferon mediates Propionibacterium acnes-induced hypersensitivity to lipopolysaccharide in mice. Infect Immun (1992) 1.20

Structural investigations on T1 lipopolysaccharides. Eur J Biochem (1969) 1.19

The immunochemistry of Salmonella chemotype VI O-antigens. The structure of oligosaccharides from Salmonella group U (o 43) lipopolysaccharides. Biochem J (1965) 1.19

Common lipopolysaccharide specificity: new type of antigen residing in the inner core region of S- and R-form lipopolysaccharides from different families of gram-negative bacteria. Infect Immun (1983) 1.18

Lipid A, the active part of bacterial endotoxins in inducing serum colony stimulating activity and proliferation of splenic granulocyte/macrophage progenitor cells. J Cell Physiol (1976) 1.17

ELISA for antibodies to lipid A, lipopolysaccharides and other hydrophobic antigens. Infection (1990) 1.17

Structural studies on the O-antigen of Aeromonas salmonicida. Eur J Biochem (1983) 1.17

Longitudinal study of antibody response to lipopolysaccharides during chronic Pseudomonas aeruginosa lung infection in cystic fibrosis. Infect Immun (1988) 1.17

The linkage of pyrophosphorylethanolamine to heptose in the core of Salmonella minnesota lipopolysaccharides. Eur J Biochem (1971) 1.16

Nature, type of linkage, and absolute configuration of (hydroxy) fatty acids in lipopolysaccharides from Xanthomonas sinensis and related strains. J Bacteriol (1975) 1.16

Phase I trial of intravenously administered endotoxin (Salmonella abortus equi) in cancer patients. Cancer Res (1991) 1.16

Induction of hypersensitivity to endotoxin and tumor necrosis factor by sublethal infection with Salmonella typhimurium. Infect Immun (1990) 1.16

A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice. J Immunol (2001) 1.15

Endotoxins of Gram-negative bacteria. Pharmacol Ther (1981) 1.14