Published in Eur J Biochem on December 22, 1971
Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity. Proc Natl Acad Sci U S A (1973) 2.61
Lipid A and resistance of Salmonella typhimurium to antimicrobial granule proteins of human neutrophil granulocytes. Infect Immun (1984) 2.41
Enterobacterial common antigen. Bacteriol Rev (1976) 2.41
Protection against gram-negative bacteremia and endotoxemia with human monoclonal IgM antibodies. Proc Natl Acad Sci U S A (1985) 2.26
Immunochemical characterization of Brucella lipopolysaccharides and polysaccharides. Infect Immun (1981) 1.96
Functional role of antibody against "core" glycolipid of Enterobacteriaceae. J Clin Invest (1975) 1.80
Composition and antigenic activity of the oligosaccharide moiety of Haemophilus influenzae type b lipooligosaccharide. Infect Immun (1985) 1.62
Characterization of the epitope specificity of murine monoclonal antibodies directed against lipid A. Infect Immun (1992) 1.61
Induction of immunity against lethal Haemophilus influenzae type b infection by Escherichia coli core lipopolysaccharide. J Clin Invest (1982) 1.59
Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate. Infect Immun (1984) 1.59
Immunization with R mutants of Salmonella minnesota. II. Serological response to lipid A and the lipopolysaccharide of Re mutants. Infect Immun (1977) 1.56
Antigenic heterogeneity of lipid A of Haemophilus influenzae. Infect Immun (1985) 1.50
The immunogenicity and antigenicity of lipid A are influenced by its physicochemical state and environment. Infect Immun (1987) 1.49
A broadly cross-protective monoclonal antibody binding to Escherichia coli and Salmonella lipopolysaccharides. Infect Immun (1993) 1.49
Protection against gram-negative infections with antiserum to lipid A from Salmonella minnesota R595. Infect Immun (1974) 1.47
Role of meningococcal endotoxin in meningococcal purpura. J Exp Med (1974) 1.45
Immunochemical characterization of rough Brucella lipopolysaccharides. Infect Immun (1984) 1.45
Immunization with R mutants of Salmonella minnesota. II. Comparison of the protective effect of immunization with lipid A and the Re mutant. Infect Immun (1977) 1.39
Neutralization of meningococcal endotoxin by antibody to core glycolipid. J Exp Med (1978) 1.38
Nontoxic lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023. J Bacteriol (1983) 1.37
Specific murine B-cell activation by synthetic single-and double-stranded polynucleotides. J Exp Med (1973) 1.37
Antigenic properties of Chlamydia trachomatis lipopolysaccharide. Infect Immun (1985) 1.34
Vaccines containing purified GM2 ganglioside elicit GM2 antibodies in melanoma patients. Proc Natl Acad Sci U S A (1987) 1.30
Radioimmunoassay for Gram-negative bacterial lipopolysaccharide O antigens: influence of antigen solubility. Infect Immun (1979) 1.29
Role for endotoxin in the leukocyte infiltration accompanying Escherichia coli inflammation. Infect Immun (1982) 1.29
Purification and characterization of lipooligosaccharides from four strains of "Haemophilus somnus". Infect Immun (1988) 1.29
Serospecific antigens of Legionella pneumophila. J Bacteriol (1986) 1.27
Spontaneous release of lipopolysaccharide by Pseudomonas aeruginosa. J Bacteriol (1983) 1.27
Isolation and characterization of murine monoclonal antibodies specific for gram-negative bacterial lipopolysaccharide: association of cross-genus reactivity with lipid A specificity. Infect Immun (1987) 1.26
Lipid A antiserum-mediated protection against lipopolysaccharide- and lipid A-induced fever and skin necrosis. Infect Immun (1977) 1.23
Lipid A and anti-lipid A. Infect Immun (1979) 1.23
Macrophage stimulation by bacterial lipopolysaccharides. II. Evidence for differentiation signals delivered by lipid A and by a protein rich fraction of lipopolysaccharides. J Exp Med (1978) 1.22
Production of monoclonal antibodies specific for two distinct steric portions of the glycolipid ganglio-N-triosylceramide (asialo GM2). J Exp Med (1979) 1.21
Biological activities of lipopolysaccharides and lipid A from Rhodospirillaceae. Infect Immun (1977) 1.21
Characterization of two different antibody specificities recognizing distinct antigenic determinants in free lipid A of Escherichia coli. Infect Immun (1985) 1.19
Cross-reactivity of major outer membrane proteins of Enterobacteriaceae, studied by crossed immunoelectrophoresis. J Bacteriol (1980) 1.18
Common lipopolysaccharide specificity: new type of antigen residing in the inner core region of S- and R-form lipopolysaccharides from different families of gram-negative bacteria. Infect Immun (1983) 1.18
The polysaccharide portion plays an indispensable role in Salmonella lipopolysaccharide-induced activation of NF-kappaB through human toll-like receptor 4. Infect Immun (2002) 1.14
Analysis of bypass activation of C3 by endotoxic LPS and loss of this potency. Immunology (1973) 1.13
Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists. Cell Death Differ (2013) 1.12
Retention of bacterial lipopolysaccharide at the site of subcutaneous injection. Infect Immun (1989) 1.11
Mouse monoclonal antibodies reactive with J5 lipopolysaccharide exhibit extensive serological cross-reactivity with a variety of gram-negative bacteria. Infect Immun (1984) 1.09
Comparative immunochemistry of lipopolysaccharides from Branhamella catarrhalis strains. Infect Immun (1991) 1.06
Characterization of the binding epitope of a monoclonal antibody to sulphatide. Biochem J (1988) 1.05
A 28,000-dalton protein of normal mouse serum binds specifically to the inner core region of bacterial lipopolysaccharide. Infect Immun (1985) 1.04
Lipid A-induced tolerance and hyperreactivity to hypothermia in mice. Infect Immun (1978) 1.04
Lipopolysaccharide structures in Enterobacteriaceae, Pseudomonas aeruginosa, and Vibrio cholerae are immunologically related to Campylobacter spp. Infect Immun (1986) 1.01
Synthetic Salmonella-type lipid A antigen with high serological specificity. Infect Immun (1986) 0.99
Humoral immune response of rabbits to acholeplasmal lipoglycans. Infect Immun (1980) 0.96
Immunogenicity and antigenicity of synthetic Escherichia coli lipid A. Infect Immun (1986) 0.96
Bacteroidaceae in thromboembolic disease: effects of cell wall components on blood coagulation in vivo and in vitro. Infect Immun (1973) 0.94
Induction of IgG in young nude mice by lipid A or thymus grafts. J Exp Med (1976) 0.94
Relationship of structure to function in bacterial endotoxins. IX. Differences in the lipid moiety of endotoxic glycolipids. J Bacteriol (1976) 0.93
Ability of gonococcal and meningococcal lipooligosaccharides to clot Limulus amebocyte lysate. Infect Immun (1992) 0.93
Induction of IgG by lipid A in the newborn mouse. J Exp Med (1974) 0.90
Anti-idiotypic antibodies as probes of protein active sites: application to cholera toxin subunit B. Proc Natl Acad Sci U S A (1987) 0.88
Antilipopolysaccharide antibodies and differential diagnosis of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis. J Clin Microbiol (1989) 0.86
Endotoxin neutralization with rabbit antisera to Escherichia coli J5 and other gram-negative bacteria. Infect Immun (1987) 0.85
Protection of mice against the lethal toxicity of a lipopolysaccharide (LPS) by immunization with anti-idiotype antibody to a monoclonal antibody to lipid A from Eikenella corrodens LPS. Infect Immun (1990) 0.83
Inhibition of lipopolysaccharide mitogenicity with characterized anti-lipid A monoclonal antibodies. Immunology (1985) 0.80
Antibody- and complement-dependent cell injury assayed by 51Cr release from human peripheral blood mononuclear cells pretreated with lipopolysaccharide. Infect Immun (1987) 0.80
Binding activity of a murine anti-lipid A monoclonal antibody. Infect Immun (1985) 0.80
Characteristics of lipid A-protein complex from endotoxin of Shigella dysenteriae type 1 (S and R strains). Infect Immun (1979) 0.80
Immune response of rabbits to lipid A: influence of immunogen preparation and distribution of various lipid A specificities. Infect Immun (1993) 0.79
Bactericidal monoclonal antibody against Moraxella catarrhalis lipooligosaccharide cross-reacts with Haemophilus Spp. Curr Microbiol (2007) 0.79
Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA. J Biol Chem (2015) 0.76
Effects of structural variations in synthetic glycolipids upon mitogenicity for spleen lymphocytes, adjuvancy for humoral immune response and on anti-tumour potential. Br J Cancer (1982) 0.76
Lipid A dependence of the ocular response to circulating endotoxin in rabbits. Infect Immun (1980) 0.76
Studies of the specificity and cross-reactions of antibodies to lipid A found in juvenile arthritis. Clin Diagn Lab Immunol (1995) 0.75
GD3 expression by cultured human tumor cells of neuroectodermal origin. Acta Neuropathol (1989) 0.75
The Combining Sites of Anti-lipid A Antibodies Reveal a Widely Utilized Motif Specific for Negatively Charged Groups. J Biol Chem (2016) 0.75
Biological properties of lipid A isolated from Flavobacterium meningosepticum. Clin Diagn Lab Immunol (2001) 0.75
[Lipopolysaccharides, endotoxins and O-antigens of gram-negative bacteria: chemical structure, biologic effect and serologic properties]. Infection (1987) 0.75
In vivo activation of mouse spleen lymphocytes by lipid A in carrier-free form. Immunology (1982) 0.75
[Lipoid A antibody titer in humans]. Infection (1987) 0.75
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science (1998) 37.15
A new method for the extraction of R lipopolysaccharides. Eur J Biochem (1969) 22.41
Immunochemistry of O and R antigens of Salmonella and related Enterobacteriaceae. Bacteriol Rev (1966) 13.42
Galactosamine-induced sensitization to the lethal effects of endotoxin. Proc Natl Acad Sci U S A (1979) 6.77
Electrodialysis of lipopolysaccharides and their conversion to uniform salt forms. Eur J Biochem (1975) 5.29
The mitogenic effect of lipopolysaccharide on bone marrow-derived mouse lymphocytes. Lipid A as the mitogenic part of the molecule. J Exp Med (1973) 4.74
Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice. J Exp Med (1987) 4.63
Picogram-sensitive assay for endotoxin: gelation of Limulus polyphemus blood cell lysate induced by purified lipopolysaccharides and lipid A from Gram-negative bacteria. Biochim Biophys Acta (1972) 4.45
Nature and linkages of the fatty acids present in the lipid-A component of Salmonella lipopolysaccharides. Eur J Biochem (1972) 4.15
Interaction of lipopolysaccharides and lipid A with complement. Eur J Biochem (1971) 4.15
Structural investigations on the 2-keto-3-deoxyoctonate region of lipopolysaccharides. Eur J Biochem (1970) 4.14
Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities. Eur J Biochem (1985) 3.76
The lipoprotein of the outer membrane of Escherichia coli: a B-lymphocyte mitogen. J Exp Med (1975) 3.55
Structural relationship of Salmonella O and R antigens. Ann N Y Acad Sci (1966) 3.54
Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect Immun (1986) 3.42
Preparation and properties of a standardized lipopolysaccharide from salmonella abortus equi (Novo-Pyrexal). Zentralbl Bakteriol Orig A (1979) 3.08
Biological activities of lipid A complexed with bovine-serum albumin. Eur J Biochem (1972) 3.04
Synthesis and use of O-stearoyl polysaccharides in passive hemagglutination and hemolysis. Eur J Biochem (1967) 2.99
Biochemical studies on lipopolysaccharides of Salmonella R mutants. 6. Investigations on the structure of the lipid A component. Eur J Biochem (1969) 2.93
Tumor necrosis factor alpha mediates lethal activity of killed gram-negative and gram-positive bacteria in D-galactosamine-treated mice. Infect Immun (1991) 2.34
Induction of tolerance to lipopolysaccharide (LPS)-D-galactosamine lethality by pretreatment with LPS is mediated by macrophages. Infect Immun (1988) 2.23
[Immunochemical studies of K antigens from Escherichia coli. II. K antigen from E. coli 08:K42(A):H-]. Biochem Z (1965) 2.20
Differential determination of the 3-Deoxy-D-mannooctulosonic acid residues in lipopolysaccharides of Salmonella minnesota rough mutants. Eur J Biochem (1983) 2.12
Granulocyte activation by endotoxin. I. Correlation between adherence and other granulocyte functions, and role of endotoxin structure on biologic activity. J Immunol (1983) 2.06
Modification of the silver staining technique to detect lipopolysaccharide in polyacrylamide gels. J Clin Microbiol (1990) 2.02
Bacterial endotoxins. The second Carl Prausnitz Memorial Lecture. Int Arch Allergy Appl Immunol (1975) 1.97
A new gene cluster rfe concerned with the biosynthesis of Salmonella lipopolysaccharide. J Gen Microbiol (1970) 1.91
Chemistry and immunochemistry of bacterial lipopolysaccharides as cell wall antigens and endotoxins. Prog Allergy (1983) 1.86
Interaction of lipopolysaccharides with plasma high-density lipoprotein in rats. Infect Immun (1980) 1.85
Lipid A: chemical structure and biological activity. J Infect Dis (1973) 1.73
Diurnal variations in the human host response to endotoxin. J Infect Dis (1996) 1.71
Chemical structure and biological activities of lipid A's from various bacterial families. Naturwissenschaften (1978) 1.69
The chemical structure of lipid A. Demonstration of amide-linked 3-acyloxyacyl residues in Salmonella minnesota Re lipopolysaccharide. Eur J Biochem (1982) 1.67
The role of the physical state of lipopolysaccharides in the interaction with complement. High molecular weight as prerequisite for the expression of anti-complementary activity. Eur J Biochem (1976) 1.64
Studies on the structure of lipopolysaccharides of Salmonella minnesota and Salmonella typhimurium R strains. Biochem J (1965) 1.60
Biological activities of synthetic lipid A analogs: pyrogenicity, lethal toxicity, anticomplement activity, and induction of gelation of Limulus amoebocyte lysate. Infect Immun (1984) 1.59
Bacterial endotoxins: chemical structure, biological activity and role in septicaemia. Scand J Infect Dis Suppl (1982) 1.56
Physical state and biological activity of lipopolysaccharides. Toxicity and immunogenicity of the lipid A component. Z Immunitatsforsch Exp Klin Immunol (1975) 1.55
[Investigations on the Typing of salmonella R-forms. IV. Typing of S. minnesota-R-mutants by antibiotics]. Zentralbl Bakteriol Orig (1970) 1.55
Time course of cellular distribution of endotoxin in liver, lungs and kidneys of rats. Br J Exp Pathol (1982) 1.54
Daily subcutaneous administration of human growth hormone in growth hormone deficient children. Acta Paediatr Scand (1986) 1.53
Immunogenic properties of lipid A. Rev Infect Dis (1984) 1.51
A lipopolysaccharide-binding cell-surface protein from Salmonella minnesota. Isolation, partial characterization and occurrence in different Enterobacteriaceae. Eur J Biochem (1979) 1.49
[Growth and lipopolysaccharide (O-antigen) levels of salmonella in cultures of agar media]. Zentralbl Bakteriol Orig (1966) 1.49
A new class of heptose-defective mutant of Salmonella typhimurium. Eur J Biochem (1973) 1.48
Composition of lipopolysaccharides from Myxococcus fulvus and other fruiting and non-fruiting myxobacteria. Eur J Biochem (1974) 1.46
Comparative immunochemistry of lipopolysaccharides from typable and polyagglutinable Pseudomonas aeruginosa strains isolated from patients with cystic fibrosis. J Clin Microbiol (1988) 1.46
The immunochemistry of Salmonella chemotype VI O-antigens. The structure of oligosaccharides from Salmonella group G (o 13,22) lipopolysaccharides. Biochem J (1965) 1.46
[Antibiotic sensitivity in S- and R-forms of Salmonella minnesota]. Naturwissenschaften (1968) 1.45
Isolation, purification, and chemical analysis of the lipopolysaccharide and lipid A of Acinetobacter calcoaceticus NCTC 10305. Eur J Biochem (1982) 1.39
Pyrogenicity and immunogenicity of lipid A complexed with bovine serum albumin or human serum albumin. Infect Immun (1973) 1.38
Nontoxic lipopolysaccharide from Rhodopseudomonas sphaeroides ATCC 17023. J Bacteriol (1983) 1.37
Biological activities of chemically modified endotoxins. Eur J Biochem (1971) 1.36
Induction of hyperreactivity to endotoxin in mice by Coxiella burnetii. Infect Immun (1984) 1.36
Lipid A, the endotoxic center of bacterial lipopolysaccharides: relation of chemical structure to biological activity. Prog Clin Biol Res (1987) 1.35
Biochemical studies on lipopolysaccharides of Salmonella R mutants. 4. Phosphate groups linked to heptose units and their absence in some R lipopolysaccharides. Eur J Biochem (1968) 1.35
Recent results on the biochemistry of the cell wall lipopolysaccharides of Salmonella bacteria. Angew Chem Int Ed Engl (1970) 1.35
Endotoxic properties of chemically synthesized lipid A part structures. Comparison of synthetic lipid A precursor and synthetic analogues with biosynthetic lipid A precursor and free lipid A. Eur J Biochem (1984) 1.33
Occurrence of 3-amino-3,6-dideoxyhexoses in Salmonella and related bacteria. J Bacteriol (1967) 1.30
Relations between structures of three K polysaccharides of Escherichia coli and cross-reactivity in antipneumococcal sera. J Bacteriol (1968) 1.30