Published in Biochem J on April 15, 1998
Nitric oxide and peroxynitrite in health and disease. Physiol Rev (2007) 15.49
Nitrite-dependent nitric oxide production pathway: implications for involvement of active nitrogen species in photoinhibition in vivo. Philos Trans R Soc Lond B Biol Sci (2000) 1.26
Role of oxidative stress and nitric oxide in atherothrombosis. Front Biosci (2008) 1.10
Role of peroxynitrite in the redox regulation of cell signal transduction pathways. Front Biosci (Landmark Ed) (2009) 1.07
Hydrogen peroxide activates focal adhesion kinase and c-Src by a phosphatidylinositol 3 kinase-dependent mechanism and promotes cell migration in Caco-2 cell monolayers. Am J Physiol Gastrointest Liver Physiol (2010) 0.97
Astrocyte mitochondria in in vitro models of ischemia. J Bioenerg Biomembr (2004) 0.89
Impaired response to interferon-gamma in activated macrophages due to tyrosine nitration of STAT1 by endogenous nitric oxide. Br J Pharmacol (2001) 0.88
Tyrosine nitration in blood vessels occurs with increasing nitric oxide concentration. Br J Pharmacol (1999) 0.84
Catalytic antioxidants to treat amyotropic lateral sclerosis. Expert Opin Investig Drugs (2006) 0.83
Oxidative and Nitrosative Stress and Immune-Inflammatory Pathways in Patients with Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS). Curr Neuropharmacol (2014) 0.79
Role of inflammation and oxidative stress mediators in gliomas. Cancers (Basel) (2010) 0.78
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci U S A (1990) 16.34
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem (1969) 15.62
Focal adhesions, contractility, and signaling. Annu Rev Cell Dev Biol (1996) 9.95
Reactive oxygen species and the central nervous system. J Neurochem (1992) 4.27
Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys (1992) 4.12
Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med (1997) 3.74
Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci (1997) 3.08
Oxidative chemistry of peroxynitrite. Methods Enzymol (1994) 3.03
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol (1994) 2.65
An essential role for free radicals and derived species in signal transduction. FASEB J (1997) 2.50
Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci Lett (1982) 1.89
Evidence of neuronal oxidative damage in Alzheimer's disease. Am J Pathol (1996) 1.87
Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation. FEBS Lett (1996) 1.87
The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury. Shock (1996) 1.78
Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis. Proc Natl Acad Sci U S A (1995) 1.70
Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture. J Neurochem (1995) 1.66
Bioenergetic and oxidative stress in neurodegenerative diseases. Life Sci (1995) 1.43
Peroxynitrite-mediated nitration of tyrosine residues in Escherichia coli glutamine synthetase mimics adenylylation: relevance to signal transduction. Proc Natl Acad Sci U S A (1996) 1.35
Nitric oxide-mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases. J Neurochem (1997) 1.33
Relationships between phosphoinositide and calcium responses to muscarinic agonists in astrocytoma cells. Mol Pharmacol (1984) 1.19
Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. J Neurochem (1995) 1.10
Peroxynitrite: a two-faced metabolite of nitric oxide. Life Sci (1997) 1.09
Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis. Neurosci Lett (1995) 1.08
Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study. J Chem Neuroanat (1996) 0.97
Phosphoinositide signaling in human brain. Prog Neurobiol (1996) 0.92
Nerve growth factor protects PC12 cells against peroxynitrite-induced apoptosis via a mechanism dependent on phosphatidylinositol 3-kinase. J Neurochem (1997) 0.88
Cholinergic stimulation of AP-1 and NF kappa B transcription factors is differentially sensitive to oxidative stress in SH-SY5Y neuroblastoma: relationship to phosphoinositide hydrolysis. J Neurosci (1996) 0.88
Peroxynitrite-induced tyrosine nitration and phosphorylation in human platelets. Free Radic Biol Med (1997) 0.87
Glutathione protects astrocytes from peroxynitrite-mediated mitochondrial damage: implications for neuronal/astrocytic trafficking and neurodegeneration. Dev Neurosci (1996) 0.86
Homologous and heterologous regulation of receptor-stimulated phosphoinositide hydrolysis. Eur J Pharmacol (1995) 0.85
Cholinergic activation of phosphoinositide signaling is impaired in Alzheimer's disease brain. Neurobiol Aging (1997) 0.83
Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc Natl Acad Sci U S A (2001) 9.40
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling. Prog Neurobiol (2001) 6.12
Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. J Biol Chem (1991) 5.84
Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys (1991) 4.71
Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy. J Cell Mol Med (2004) 4.16
Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys (1992) 4.12
Peroxynitrite formation from macrophage-derived nitric oxide. Arch Biochem Biophys (1992) 3.68
Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide. Chem Res Toxicol (1993) 3.16
Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci (1997) 3.08
Designed protein pores as components for biosensors. Chem Biol (1997) 2.98
Subunit stoichiometry of staphylococcal alpha-hemolysin in crystals and on membranes: a heptameric transmembrane pore. Proc Natl Acad Sci U S A (1994) 2.87
Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts. Proc Natl Acad Sci U S A (1996) 2.77
ALS, SOD and peroxynitrite. Nature (1993) 2.64
Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J Clin Invest (1994) 2.62
Bactericidal activity of peroxynitrite. Arch Biochem Biophys (1992) 2.61
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. Science (1999) 2.17
Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse. Cell (1997) 2.13
Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite. J Neurochem (1997) 2.13
CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium. J Neurochem (2001) 2.11
In vitro transcription and processing of a yeast tRNA gene containing an intervening sequence. Cell (1979) 2.04
Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium. J Biol Chem (2000) 1.98
Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite. J Biol Chem (2000) 1.97
Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta. J Biol Chem (2001) 1.90
The comparative toxicity of nitric oxide and peroxynitrite to Escherichia coli. Arch Biochem Biophys (1995) 1.87
Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice. Mol Psychiatry (2011) 1.86
Evidence for in vivo peroxynitrite production in human acute lung injury. Am J Respir Crit Care Med (1995) 1.84
Linking community-based blood pressure measurement to clinical care: a randomized controlled trial of outreach and tracking by community health workers. Am J Public Health (1999) 1.81
Peroxynitrite-mediated oxidation of dihydrorhodamine 123. Free Radic Biol Med (1994) 1.79
Protein catalysis of the retinal subpicosecond photoisomerization in the primary process of bacteriorhodopsin photosynthesis. Science (1993) 1.75
Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases. Nat Med (1999) 1.73
Peroxynitrite-induced luminol chemiluminescence. Biochem J (1993) 1.63
alpha-Hemolysin, gamma-hemolysin, and leukocidin from Staphylococcus aureus: distant in sequence but similar in structure. Protein Sci (1997) 1.62
Conversion of xanthine dehydrogenase to oxidase in ischemic rat intestine: a reevaluation. Am J Physiol (1988) 1.62
Strain dynamics of ultrathin VO₂ film grown on TiO₂ (001) and the associated phase transition modulation. Nano Lett (2014) 1.61
Reactions between nitric oxide, superoxide, and peroxynitrite: footprints of peroxynitrite in vivo. Adv Pharmacol (1995) 1.59
Asthma and the home environment of low-income urban children: preliminary findings from the Seattle-King County healthy homes project. J Urban Health (2000) 1.59
Reovirus infection of cancer cells is not due to activated Ras pathway. Cancer Gene Ther (2008) 1.56
Microtubule dysfunction by posttranslational nitrotyrosination of alpha-tubulin: a nitric oxide-dependent mechanism of cellular injury. Proc Natl Acad Sci U S A (1999) 1.55
Myeloperoxidase and horseradish peroxidase catalyze tyrosine nitration in proteins from nitrite and hydrogen peroxide. Arch Biochem Biophys (1998) 1.54
Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase. J Neurochem (1999) 1.52
Immediate post-abortal insertion of the frameless GyneFix IUD: initial experience in China. Br J Fam Plann (2000) 1.50
Crc is involved in catabolite repression control of the bkd operons of Pseudomonas putida and Pseudomonas aeruginosa. J Bacteriol (2000) 1.49
Dependency plots suggest the kinetic structure of ion channels. Proc Biol Sci (1992) 1.48
Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis. Gastroenterology (1995) 1.48
Astrocyte elevated gene-1 is a proliferation promoter in breast cancer via suppressing transcriptional factor FOXO1. Oncogene (2009) 1.46
Identification of an antiapoptotic protein complex at death receptors. Cell Death Differ (2008) 1.46
Do women with premenstrual symptoms self-medicate with caffeine? Epidemiology (1991) 1.44
Nicastrin binds to membrane-tethered Notch. Nat Cell Biol (2001) 1.44
Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4. J Biol Chem (2000) 1.38
Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation. J Neurosci (1998) 1.37
Spontaneous oligomerization of a staphylococcal alpha-hemolysin conformationally constrained by removal of residues that form the transmembrane beta-barrel. Protein Eng (1997) 1.36
Isolation of a Putative Carboxysomal Carbonic Anhydrase Gene from the Cyanobacterium Synechococcus PCC7942. Plant Physiol (1992) 1.36
Infection of cord blood monocyte-derived macrophages with human immunodeficiency virus type 1. J Virol (1992) 1.36
Cell signaling by reactive nitrogen and oxygen species in atherosclerosis. Free Radic Biol Med (2000) 1.35
Mechanisms of cerebral vasodilation by superoxide, hydrogen peroxide, and peroxynitrite. Am J Physiol (1996) 1.34
iNOS and nitrotyrosine expression after spinal cord injury. J Neurotrauma (2001) 1.33
Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases. Oncogene (2007) 1.30
Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium. Brain Res (2001) 1.30
Syntheses of peroxynitrite: to go with the flow or on solid grounds? Methods Enzymol (1996) 1.29
Tumor necrosis factor and interleukin 1 alpha increase vascular endothelial permeability. Am J Physiol (1989) 1.27
Opposing actions of phosphatidylinositol 3-kinase and glycogen synthase kinase-3beta in the regulation of HSF-1 activity. J Neurochem (2000) 1.26
Dexamethasone differentially regulates expression of carboxylesterase genes in humans and rats. Drug Metab Dispos (2000) 1.26
Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury. Am J Physiol (1989) 1.25
Socio-economic disparities in maternal mortality in China between 1996 and 2006. BJOG (2010) 1.25
Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L. J Neurochem (1997) 1.23
Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family. J Biol Chem (1999) 1.23
High Ca2+ concentrations induce a low activity mode and reveal Ca2(+)-independent long shut intervals in BK channels from rat muscle. J Physiol (1996) 1.22
Extensive tyrosine nitration in human myocardial inflammation: evidence for the presence of peroxynitrite. Crit Care Med (1997) 1.21
Hyperoxia increases H2O2 production by brain in vivo. J Appl Physiol (1985) (1987) 1.20
Osteogenesis in cranial defects: reassessment of the concept of critical size and the expression of TGF-beta isoforms. Plast Reconstr Surg (2000) 1.20
Circulating xanthine oxidase: potential mediator of ischemic injury. Am J Physiol (1990) 1.17
A frequent Y chromosome b2/b3 subdeletion shows strong association with male infertility in Han-Chinese population. Hum Reprod (2007) 1.17
The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration. J Neurosci Res (1992) 1.17
Mechanisms of peroxynitrite-induced injury to pulmonary surfactants. Am J Physiol (1993) 1.16
High affinity choline transport and acetylCoA production in brain and their roles in the regulation of acetylcholine synthesis. Brain Res (1979) 1.16
Rapid and irreversible inactivation of protein tyrosine phosphatases PTP1B, CD45, and LAR by peroxynitrite. Arch Biochem Biophys (1999) 1.15
Periodic ZnO nanorod arrays defined by polystyrene microsphere self-assembled monolayers. Nano Lett (2006) 1.14
Realtime photoacoustic microscopy of murine cardiovascular dynamics. Opt Express (2008) 1.13
Peroxynitrite inhibition of oxygen consumption and sodium transport in alveolar type II cells. Am J Physiol (1994) 1.13
Antibodies that recognize nitrotyrosine. Methods Enzymol (1996) 1.12
Ceramic thin-film formation on functionalized interfaces through biomimetic processing. Science (1994) 1.12
Effect of ethidium on the torsion constants of linear and supercoiled DNAs. Biophys Chem (1991) 1.11
On the molecular mechanisms of the Schiff base deprotonation during the bacteriorhodopsin photocycle. Proc Natl Acad Sci U S A (1986) 1.11
Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. J Neurochem (1995) 1.10
On the pH-dependent yield of hydroxyl radical products from peroxynitrite. Free Radic Biol Med (1994) 1.10
Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase. Am J Physiol (1999) 1.09
The role of peroxynitrite in nitric oxide-mediated toxicity. Curr Top Microbiol Immunol (1995) 1.09
Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes. Genes Immun (2009) 1.08
Biochemical effects of phosphatidylcholine treatment in rats. Biochem Pharmacol (1984) 1.08
Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat. J Neurosci Res (1989) 1.07
PS1 N- and C-terminal fragments form a complex that functions in APP processing and Notch signaling. Proc Natl Acad Sci U S A (2001) 1.07
Cellular localization of gelatinases and tissue inhibitors of metalloproteinases during follicular growth, ovulation, and early luteal formation in the rat. Biol Reprod (2001) 1.07
Sensitivity of the essential zinc-thiolate moiety of yeast alcohol dehydrogenase to hypochlorite and peroxynitrite. Biochemistry (1995) 1.06
Centrifugal enhancement of human immunodeficiency virus type 1 infection and human cytomegalovirus gene expression in human primary monocyte/macrophages in vitro. J Leukoc Biol (1993) 1.06
Peroxynitrite, a product of superoxide and nitric oxide, produces coronary vasorelaxation in dogs. J Pharmacol Exp Ther (1994) 1.06
L-arginine chlorination products inhibit endothelial nitric oxide production. J Biol Chem (2001) 1.06