Published in Science on May 08, 1998
Etiology of interepidemic periods of mosquito-borne disease. Proc Natl Acad Sci U S A (2000) 4.75
Hemagglutinin sequence clusters and the antigenic evolution of influenza A virus. Proc Natl Acad Sci U S A (2002) 4.02
The effect of antibody-dependent enhancement on the transmission dynamics and persistence of multiple-strain pathogens. Proc Natl Acad Sci U S A (1999) 3.06
Antibody recognition of Plasmodium falciparum erythrocyte surface antigens in Kenya: evidence for rare and prevalent variants. Infect Immun (1999) 2.62
Transmission dynamics and epidemiology of dengue: insights from age-stratified sero-prevalence surveys. Philos Trans R Soc Lond B Biol Sci (1999) 2.57
Dynamics and selection of many-strain pathogens. Proc Natl Acad Sci U S A (2002) 2.54
Role of genomic typing in taxonomy, evolutionary genetics, and microbial epidemiology. Clin Microbiol Rev (2001) 2.37
Dynamic effects of antibody-dependent enhancement on the fitness of viruses. Proc Natl Acad Sci U S A (2005) 2.02
The generation of influenza outbreaks by a network of host immune responses against a limited set of antigenic types. Proc Natl Acad Sci U S A (2007) 1.63
Geographic subdivision of the range of the malaria parasite Plasmodium vivax. Emerg Infect Dis (2001) 1.59
Natural selection and evolution of streptococcal virulence genes involved in tissue-specific adaptations. J Bacteriol (2004) 1.57
On the determinants of population structure in antigenically diverse pathogens. Proc Biol Sci (2002) 1.42
Niche and neutral effects of acquired immunity permit coexistence of pneumococcal serotypes. Science (2012) 1.39
No coexistence for free: neutral null models for multistrain pathogens. Epidemics (2008) 1.37
Patterns of antigenic diversity and the mechanisms that maintain them. J R Soc Interface (2007) 1.37
Community epidemiology framework for classifying disease threats. Emerg Infect Dis (2005) 1.28
Why are dengue virus serotypes so distantly related? Enhancement and limiting serotype similarity between dengue virus strains. Proc Biol Sci (2003) 1.23
The effects of host contact network structure on pathogen diversity and strain structure. Proc Natl Acad Sci U S A (2004) 1.22
Prevalence of the hifBC, hmw1A, hmw2A, hmwC, and hia Genes in Haemophilus influenzae Isolates. J Clin Microbiol (2004) 1.19
Serotype cycles in cholera dynamics. Proc Biol Sci (2006) 1.14
Heterosubtypic immunity to influenza A virus infections in mallards may explain existence of multiple virus subtypes. PLoS Pathog (2013) 1.13
On state-space reduction in multi-strain pathogen models, with an application to antigenic drift in influenza A. PLoS Comput Biol (2007) 1.09
Cross-species pathogen transmission and disease emergence in primates. Ecohealth (2010) 1.08
Vaccination and the dynamics of immune evasion. J R Soc Interface (2007) 1.06
Improving the realism of deterministic multi-strain models: implications for modelling influenza A. J R Soc Interface (2008) 1.06
Extensive genomic variation within clonal complexes of Neisseria meningitidis. Genome Biol Evol (2011) 1.06
Persistence of hyperinvasive meningococcal strain types during global spread as recorded in the PubMLST database. PLoS One (2012) 1.04
Population dynamics of genetically diverse Plasmodium falciparum lineages: community-based prospective study in rural Amazonia. Parasitology (2009) 1.04
Decline of meticillin-resistant Staphylococcus aureus in Oxfordshire hospitals is strain-specific and preceded infection-control intensification. BMJ Open (2011) 1.02
Incorporating demographic stochasticity into multi-strain epidemic models: application to influenza A. J R Soc Interface (2009) 1.01
Group B streptococcal surface proteins as targets for protective antibodies: identification of two novel proteins in strains of serotype V. Infect Immun (1999) 1.01
The effect of immune selection on the structure of the meningococcal opa protein repertoire. PLoS Pathog (2008) 0.99
Low-dimensional clustering detects incipient dominant influenza strain clusters. Protein Eng Des Sel (2010) 0.98
Evolution of the multi-domain structures of virulence genes in the human malaria parasite, Plasmodium falciparum. PLoS Comput Biol (2012) 0.97
Discrete-Event Models of Mixed-Phenotype Plasmodium falciparum Malaria. Simulation (1999) 0.97
The roles of competition and mutation in shaping antigenic and genetic diversity in influenza. PLoS Pathog (2013) 0.95
Modeling rotavirus strain dynamics in developed countries to understand the potential impact of vaccination on genotype distributions. Proc Natl Acad Sci U S A (2011) 0.93
Influenza A gradual and epochal evolution: insights from simple models. PLoS One (2009) 0.93
Large-scale spatial and temporal genetic diversity of feline calicivirus. J Virol (2012) 0.92
The impact of cross-immunity, mutation and stochastic extinction on pathogen diversity. Proc Biol Sci (2004) 0.92
Natural, persistent oscillations in a spatial multi-strain disease system with application to dengue. PLoS Comput Biol (2013) 0.91
The antigenic evolution of influenza: drift or thrift? Philos Trans R Soc Lond B Biol Sci (2013) 0.90
Influenza emergence in the face of evolutionary constraints. Proc Biol Sci (2011) 0.89
Inferring malaria parasite population structure from serological networks. Proc Biol Sci (2009) 0.89
The effects of host heterogeneity on pathogen population structure. Philos Trans R Soc Lond B Biol Sci (1999) 0.89
Pathogen diversity and hidden regimes of apparent competition. Am Nat (2012) 0.89
Epidemics with multistrain interactions: the interplay between cross immunity and antibody-dependent enhancement. Chaos (2009) 0.88
Never mind the length, feel the quality: the impact of long-term epidemiological data sets on theory, application and policy. Trends Ecol Evol (2010) 0.88
Role of stochastic processes in maintaining discrete strain structure in antigenically diverse pathogen populations. Proc Natl Acad Sci U S A (2011) 0.88
One health - an ecological and evolutionary framework for tackling Neglected Zoonotic Diseases. Evol Appl (2016) 0.88
Modelling hospital admissions for lower respiratory tract infections in the elderly in England. Epidemiol Infect (2006) 0.85
The interaction of seasonal forcing and immunity and the resonance dynamics of malaria. J R Soc Interface (2009) 0.85
Pathogen evolution and the immunological niche. Ann N Y Acad Sci (2014) 0.85
Consequences of host heterogeneity, epitope immunodominance, and immune breadth for strain competition. J Theor Biol (2010) 0.84
Host community structure and the maintenance of pathogen diversity. Proc Biol Sci (2007) 0.84
Dissecting the determinants of malaria chronicity: why within-host models struggle to reproduce infection dynamics. J R Soc Interface (2015) 0.82
The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunity. Malar J (2008) 0.82
Pathogen selection drives nonoverlapping associations between HLA loci. Proc Natl Acad Sci U S A (2013) 0.82
The dynamics, causes and possible prevention of Hepatitis E outbreaks. PLoS One (2012) 0.81
Structural identifiability analysis of some highly structured families of statespace models using differential algebra. J Math Biol (2004) 0.81
The impact of coinfections and their simultaneous transmission on antigenic diversity and epidemic cycling of infectious diseases. Biomed Res Int (2014) 0.81
Contact between bird species of different lifespans can promote the emergence of highly pathogenic avian influenza strains. Proc Natl Acad Sci U S A (2014) 0.80
Characterizing the symmetric equilibrium of multi-strain host-pathogen systems in the presence of cross immunity. J Math Biol (2005) 0.80
Identifying the age cohort responsible for transmission in a natural outbreak of Bordetella bronchiseptica. PLoS Pathog (2010) 0.79
Variation in infection length and superinfection enhance selection efficiency in the human malaria parasite. Sci Rep (2016) 0.78
Cross-Immunity and Community Structure of a Multiple-Strain Pathogen in the Tick Vector. Appl Environ Microbiol (2015) 0.78
Strain Interactions as a Mechanism for Dominant Strain Alternation and Incidence Oscillation in Infectious Diseases: Seasonal Influenza as a Case Study. PLoS One (2015) 0.78
Lineage structure of Streptococcus pneumoniae may be driven by immune selection on the groEL heat-shock protein. Sci Rep (2017) 0.78
Contrasting within- and between-host immune selection shapes Neisseria Opa repertoires. Sci Rep (2014) 0.77
Bifurcation, stability, and cluster formation of multi-strain infection models. J Math Biol (2012) 0.76
Diverse evolutionary patterns of pneumococcal antigens identified by pangenome-wide immunological screening. Proc Natl Acad Sci U S A (2017) 0.76
The effects of symmetry on the dynamics of antigenic variation. J Math Biol (2013) 0.76
Evolutionary entropy determines invasion success in emergent epidemics. PLoS One (2010) 0.76
Effects of neutralizing antibodies on escape from CD8+ T-cell responses in HIV-1 infection. Philos Trans R Soc Lond B Biol Sci (2015) 0.76
Infections and cancer: the "fifty shades of immunity" hypothesis. BMC Cancer (2017) 0.75
Metabolic shift in the emergence of hyperinvasive pandemic meningococcal lineages. Sci Rep (2017) 0.75
Who acquires infection from whom and how? Disentangling multi-host and multi-mode transmission dynamics in the 'elimination' era. Philos Trans R Soc Lond B Biol Sci (2017) 0.75
Estimating the Lineage Dynamics of Human Influenza B Viruses. PLoS One (2016) 0.75
Epidemic cycling in a multi-strain SIRS epidemic network model. Theor Biol Med Model (2016) 0.75
Why does drug resistance readily evolve but vaccine resistance does not? Proc Biol Sci (2017) 0.75
Capturing the dynamics of pathogens with many strains. J Math Biol (2015) 0.75
Immune response to a variable pathogen: a stochastic model with two interlocked Darwinian entities. Comput Math Methods Med (2012) 0.75
MANTIS: an R package that simulates multilocus models of pathogen evolution. BMC Bioinformatics (2015) 0.75
No evidence for homosubtypic immunity of influenza H3 in Mallards following vaccination in a natural experimental system. Mol Ecol (2017) 0.75
Analysis of symmetries in models of multi-strain infections. J Math Biol (2013) 0.75
Association of depression and diabetes complications: a meta-analysis. Psychosom Med (2001) 8.30
NHS-wide networking and patient confidentiality. BMJ (1995) 7.38
Worldwide variations in the prevalence of symptoms of atopic eczema in the International Study of Asthma and Allergies in Childhood. J Allergy Clin Immunol (1999) 3.87
Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis. J Cell Biol (2000) 3.63
Pneumococcal vaccine campaign based in general practice. BMJ (1997) 3.50
A reproducible microanalytical method for the detection of specific RNA sequences by dot-blot hybridization. Anal Biochem (1984) 3.47
Structural and mechanistic basis of immunity toward endonuclease colicins. Nat Struct Biol (1999) 3.37
Why do symptomatic patients delay obtaining care for tuberculosis? Am J Respir Crit Care Med (1998) 3.30
Prospective randomized controlled trial of extended-release oxybutynin chloride and tolterodine tartrate in the treatment of overactive bladder: results of the OBJECT Study. Mayo Clin Proc (2001) 3.17
Black-white mortality differences by family income. Lancet (1992) 3.15
The effect of antibody-dependent enhancement on the transmission dynamics and persistence of multiple-strain pathogens. Proc Natl Acad Sci U S A (1999) 3.06
Community acquired pneumonia: aetiology and usefulness of severity criteria on admission. Thorax (1996) 2.46
Sexuality in a natural population of bacteria--Bacillus subtilis challenges the clonal paradigm. Mol Ecol (1992) 2.45
Comparison of custom and prefabricated orthoses in the initial treatment of proximal plantar fasciitis. Foot Ankle Int (1999) 2.37
Prevalence and diagnosis of chronic respiratory symptoms in adults. BMJ (1989) 2.28
Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker. J Biol Chem (2001) 2.18
Venous thromboembolic complications (VTE) in children: first analyses of the Canadian Registry of VTE. Blood (1994) 2.14
First trimester biochemical screening for trisomy 21: the role of free beta hCG, alpha fetoprotein and pregnancy associated plasma protein A. Ann Clin Biochem (1994) 2.06
Age-related changes underlie switch in netrin-1 responsiveness as growth cones advance along visual pathway. Nat Neurosci (2002) 2.06
Ty1-copia group retrotransposons are ubiquitous and heterogeneous in higher plants. Nucleic Acids Res (1992) 2.05
Chlamydia trachomatis, infertility, and population growth in sub-Saharan Africa. Sex Transm Dis (1993) 2.05
Evaluation of the Abbott LCx ligase chain reaction assay for detection of Chlamydia trachomatis and Neisseria gonorrhoeae in urine and genital swab specimens from a sexually transmitted disease clinic population. J Clin Microbiol (1998) 2.04
AIDS, HIV and the Sunday Times. Nature (1994) 2.02
Psychometric considerations in evaluating health-related quality of life measures. Qual Life Res (1993) 1.95
An outbreak of nosocomial infection due to multiply resistant Serratia marcescens: evidence of interhospital spread. J Infect Dis (1976) 1.95
Cancer screening guidelines. Am Fam Physician (2001) 1.89
Methamphetamine use and sexual and injection risk behaviors among out-of-treatment injection drug users. Am J Drug Alcohol Abuse (1999) 1.88
Outcome of pediatric thromboembolic disease: a report from the Canadian Childhood Thrombophilia Registry. Pediatr Res (2000) 1.86
Ethnic differences in stroke mortality between non-Hispanic whites, Hispanic whites, and blacks. The National Longitudinal Mortality Study. Stroke (1994) 1.85
Evaluation of social status as a contributing factor to the stroke belt region of the United States. Stroke (1997) 1.81
Developing and evaluating cross-cultural instruments from minimum requirements to optimal models. Qual Life Res (1993) 1.78
Proinflammatory interactions of pyocyanin and 1-hydroxyphenazine with human neutrophils in vitro. J Infect Dis (1990) 1.77
In vitro stimulation of neutrophil motility by levamisole: maintenance of cgmp levels in chemotactically stimulated levamisole-treated neutrophils. J Immunol (1976) 1.76
Wolman disease successfully treated by bone marrow transplantation. Bone Marrow Transplant (2000) 1.75
Mineralogy of a mudstone at Yellowknife Bay, Gale crater, Mars. Science (2013) 1.75
Sonic hedgehog is required for cardiac outflow tract and neural crest cell development. Dev Biol (2005) 1.74
The association between prenatal care and birth weight among women exposed to cocaine in New York City. JAMA (1993) 1.72
Signs and symptoms of "asymptomatic" HIV-1 infection in homosexual men. Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr (1993) 1.66
Proinflammatory interactions of pneumolysin with human neutrophils. J Infect Dis (2001) 1.62
Undermining data privacy in health information. BMJ (2001) 1.62
Antibiotic resistance--what can we do? Nat Med (1998) 1.59
Antibodies that block virus attachment to Vero cells are a major component of the human neutralizing antibody response against dengue virus type 2. J Med Virol (1995) 1.58
Clinical manifestations of AIDS in the era of pneumocystis prophylaxis. Multicenter AIDS Cohort Study. N Engl J Med (1993) 1.58
Analysis of the molecular specificities of anti-class II monoclonal antibodies by using L cell transfectants expressing HLA class II molecules. J Immunol (1988) 1.54
Chronic inhalation toxicity of size-separated glass fibers in Fischer 344 rats. Fundam Appl Toxicol (1993) 1.53
Neuropsychological consequences of volatile substance abuse: a population based study of secondary school pupils. BMJ (1989) 1.53
The in vitro effects of histamine and metiamide on neutrophil motility and their relationship to intracellular cyclic nucleotide levels. J Immunol (1977) 1.49
Physicians declining patient enrollment in a critical care trial: a case study in thromboprophylaxis. Intensive Care Med (2013) 1.46
The clinical effectiveness and cost-effectiveness of cardiac resynchronisation (biventricular pacing) for heart failure: systematic review and economic model. Health Technol Assess (2007) 1.46
A cluster randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of classroom-based cognitive-behavioural therapy (CBT) in reducing symptoms of depression in high-risk adolescents. Health Technol Assess (2013) 1.46
The iron electron-nuclear double resonance (ENDOR) of two-iron ferredoxins from spinach, parsley, pig adrenal cortex and Pseudomonas putida. Biochim Biophys Acta (1971) 1.46
Maternal beta-catenin establishes a 'dorsal signal' in early Xenopus embryos. Development (1996) 1.44
Coronaviridae. Intervirology (1983) 1.42
Acute cardiomyopathy in heifers. Vet Rec (1990) 1.39
Intracellular murine hepatitis virus-specific RNAs contain common sequences. Virology (1981) 1.39
Factors affecting bile acid metabolism in cholerrheic enteropathy. Digestion (1974) 1.39
Letter: Nitroblue tetrazolium test (NBT) in the investigation of febrile patients. S Afr Med J (1973) 1.38
Comparison of polypeptides of two strains of murine hepatitis virus. Virology (1979) 1.36
The effectiveness and cost-effectiveness of cochlear implants for severe to profound deafness in children and adults: a systematic review and economic model. Health Technol Assess (2009) 1.35
Immune brachial plexus neuropathy: suggestive evidence for an inflammatory-immune pathogenesis. Neurology (1996) 1.33
Influence of antimicrobial chemotherapy on spirometric parameters and pro-inflammatory indices in severe pulmonary tuberculosis. Eur Respir J (1998) 1.32
Antibody-enhanced binding of dengue-2 virus to human platelets. Virology (1995) 1.30
Loss of function of the tuberous sclerosis 2 tumor suppressor gene results in embryonic lethality characterized by disrupted neuroepithelial growth and development. Proc Natl Acad Sci U S A (1998) 1.28
The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease (review of Technology Appraisal No. 111): a systematic review and economic model. Health Technol Assess (2012) 1.28
Energy expenditure during bicycling. J Appl Physiol (1985) (1990) 1.28
Psychosocial interest, medical interviews, and the recognition of depression. Arch Fam Med (1994) 1.28
Acinetobacter calcoaceticus outbreak associated with peritoneal dialysis. Am J Epidemiol (1978) 1.28
Protective activity of a human respiratory syncytial virus immune globulin prepared from donors screened by microneutralization assay. J Infect Dis (1992) 1.27
PrM- and cell-binding domains of the dengue virus E protein. J Virol (1999) 1.27
Relationship between lung biopersistence and biological effects of man-made vitreous fibers after chronic inhalation in rats. Environ Health Perspect (1994) 1.27
AIDS publicity campaigns. Lancet (1987) 1.27
Cannabis use in the community. Br J Gen Pract (1996) 1.26
Computerised decision support systems in order communication for diagnostic, screening or monitoring test ordering: systematic reviews of the effects and cost-effectiveness of systems. Health Technol Assess (2010) 1.26
Combined clinical and computed tomographic diagnosis of primary lacrimal fossa lesions. Am J Ophthalmol (1982) 1.26
Contribution of visceral fat mass to the insulin resistance of aging. Metabolism (1995) 1.25
Challenges faced in recruiting patients from primary care practices into a physical activity intervention trial. Activity Counseling Trial Research Group. Prev Med (1999) 1.23
Iris melanoma. Nevus or malignancy? Surv Ophthalmol (1985) 1.21
Differentiation of acid-pH-dependent and -nondependent entry pathways for mouse hepatitis virus. Virology (1991) 1.21
GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction. Transl Psychiatry (2012) 1.21
Surveillance of cirrhosis for hepatocellular carcinoma: systematic review and economic analysis. Health Technol Assess (2007) 1.21
In vivo and in vitro models of demyelinating diseases: tropism of the JHM strain of murine hepatitis virus for cells of glial origin. Cell (1977) 1.20
IgA deficiency associated with partial deletion of chromosome 18. Am J Dis Child (1969) 1.20
The misuse of 'no significant difference' in British orthopaedic literature. Ann R Coll Surg Engl (2008) 1.20
Lack of pharmacokinetic interaction between nelfinavir and nevirapine. AIDS (1998) 1.19
Sympathetic ophthalmia and lymphocyte transformation. Am J Ophthalmol (1971) 1.18
Defective neutrophil motility in children with measles. J Pediatr (1976) 1.17
Autoantibody to microtubules in infectious mononucleosis. Clin Exp Immunol (1974) 1.16
Identification of the sulfolipids in the non-photosynthetic diatom Nitzschia alba. Biochim Biophys Acta (1978) 1.16
Preferential translation of reovirus mRNA by a sigma3-dependent mechanism. Virology (1997) 1.16
Sieve plate pores of Nicotiana. J Ultrastruct Res (1969) 1.15
Generation of biologically active C-reactive protein peptides by a neutral protease on the membrane of phorbol myristate acetate-stimulated neutrophils. J Immunol (1989) 1.15
Fossil fuels, transport, and public health. BMJ (2000) 1.14
Contribution of the ocean sector to the United States economy. Science (1980) 1.14
Role of social class in excess black stroke mortality. Stroke (1995) 1.13
Electricity in Volcanic Clouds: Investigations show that lightning can result from charge-separation processes in a volcanic crater. Science (1965) 1.13
Release of vasoactive cytokines by antibody-enhanced dengue virus infection of a human mast cell/basophil line. J Virol (2000) 1.13
In vitro and in vivo effects of dapsone on neutrophil and lymphocyte functions in normal individuals and patients with lepromatous leprosy. Antimicrob Agents Chemother (1981) 1.13
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity. Proc Natl Acad Sci U S A (2000) 1.12
The treatment of musculoskeletal disorders by a Mexican bonesetter (sobador). Soc Sci Med (1987) 1.12