Probing degeneracy in T-cell recognition using peptide combinatorial libraries.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMID 9577092)

Published in Immunol Today on April 01, 1998

Authors

B Hemmer1, M Vergelli, C Pinilla, R Houghten, R Martin

Author Affiliations

1: Cellular Immunology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1400, USA.

Articles citing this

Deconstructing the peptide-MHC specificity of T cell recognition. Cell (2014) 3.24

Heterologous immunity between viruses. Immunol Rev (2010) 2.20

Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood. Proc Natl Acad Sci U S A (2004) 1.80

Molecular mimicry between Helicobacter pylori antigens and H+, K+ --adenosine triphosphatase in human gastric autoimmunity. J Exp Med (2003) 1.14

Recombinant virus vaccination against "self" antigens using anchor-fixed immunogens. Cancer Res (1999) 1.10

The immunology of Epstein-Barr virus infection. Philos Trans R Soc Lond B Biol Sci (2001) 1.04

Epitope-specific in vivo protection against cytomegalovirus disease by CD8 T cells in the murine model of preemptive immunotherapy. Med Microbiol Immunol (2008) 0.97

Revisiting thymic positive selection and the mature T cell repertoire for antigen. Immunity (2014) 0.92

T-cell avidity and tuning: the flexible connection between tolerance and autoimmunity. Int Rev Immunol (2006) 0.88

CD8(+) T cells in multiple sclerosis. Expert Opin Ther Targets (2013) 0.86

Parameters determining the efficacy of adoptive CD8 T-cell therapy of cytomegalovirus infection. Med Microbiol Immunol (2012) 0.82

Specific increase in potency via structure-based design of a TCR. J Immunol (2014) 0.82

Inducing efficient cross-priming using antigen-coated yeast particles. J Immunother (2008) 0.79

Telomerase reverse transcriptase as target for anti-tumor T cell responses in humans. Springer Semin Immunopathol (2005) 0.78

Characterization of human immunodeficiency virus type 1 (HIV-1) Gag- and Gag peptide-specific CD4(+) T-cell clones from an HIV-1-seronegative donor following in vitro immunization. J Virol (2002) 0.76

IFNgamma production in peripheral blood of early Lyme disease patients to hLFAalphaL (aa326-345). BMC Musculoskelet Disord (2002) 0.75

Articles by these authors

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery. Nature (1991) 5.30

Viability and isolation of marine bacteria by dilution culture: theory, procedures, and initial results. Appl Environ Microbiol (1993) 5.09

An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1988) 4.72

One or more bound planets per Milky Way star from microlensing observations. Nature (2012) 4.68

Resistance to penicillin and cephalosporin and mortality from severe pneumococcal pneumonia in Barcelona, Spain. N Engl J Med (1995) 4.38

Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis. J Rheumatol (1995) 4.11

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat Med (2000) 3.98

Discovery of a cool planet of 5.5 Earth masses through gravitational microlensing. Nature (2006) 3.53

Trends in antimicrobial resistance of clinical isolates of Streptococcus pneumoniae in Bellvitge Hospital, Barcelona, Spain (1979-1990). Clin Infect Dis (1992) 3.37

Public-health impact of accelerated measles control in the WHO African Region 2000-03. Lancet (2005) 3.36

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform. J Mol Biol (1997) 2.95

Nurses taking on junior doctors' work: a confusion of accountability. BMJ (1996) 2.88

Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1. Kidney Int (2007) 2.87

Instrumentation of the airway in the absence of intravenous access. Paediatr Anaesth (2003) 2.73

Mapping the prion protein using recombinant antibodies. J Virol (1998) 2.64

Calcium-dependent protein kinases play an essential role in a plant defence response. EMBO J (2001) 2.53

Can prosody aid the automatic classification of dialog acts in conversational speech? Lang Speech (2000) 2.51

Identification of MHC class II-restricted peptide ligands, including a glutamic acid decarboxylase 65 sequence, that stimulate diabetogenic T cells from transgenic BDC2.5 nonobese diabetic mice. J Immunol (2001) 2.39

Treating sexually abused children with posttraumatic stress symptoms: a randomized clinical trial. J Am Acad Child Adolesc Psychiatry (2000) 2.33

A single amino acid interchange yields reciprocal CTL specificities for HIV-1 gp160. Science (1989) 2.32

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein. Nature (1996) 2.30

Topology of the 32-kd liver gap junction protein determined by site-directed antibody localizations. EMBO J (1988) 2.26

The organization of the araBAD operon of Escherichia coli. Gene (1986) 2.16

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal surface malignancies of colonic origin: a consensus statement. Society of Surgical Oncology. Ann Surg Oncol (2006) 2.13

Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease. Nat Med (1999) 2.11

Evidence-based recommendations for the use of Negative Pressure Wound Therapy in traumatic wounds and reconstructive surgery: steps towards an international consensus. Injury (2011) 2.07

Cause of death and correlation with autopsy findings in burns patients. Burns (2012) 2.07

CARE-LASS (calcein-release-assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity. J Immunol Methods (1994) 2.01

Chromosome 1 loci in Finnish schizophrenia families. Hum Mol Genet (2001) 1.95

The Use of a Helium-Oxygen Mixture during Maximum Expiratory Flow to Demonstrate Obstruction in Small Airways in Smokers. J Clin Invest (1975) 1.93

Laparoscopically assisted vaginal hysterectomy superfluous? S Afr Med J (1998) 1.92

Incidence and prevalence of epilepsy among older U.S. Medicare beneficiaries. Neurology (2012) 1.92

The relationships between interphase Schwann cells and axons before myelination: a quantitative electron microscopic study. Dev Biol (1973) 1.91

Skewed T-cell receptor repertoire in genetically identical twins correlates with multiple sclerosis. Nature (1993) 1.89

Axillary plexus block using a peripheral nerve stimulator: single or multiple injections. Can J Anaesth (1992) 1.87

Long-term safety and efficacy of etanercept in patients with rheumatoid arthritis. J Rheumatol (2001) 1.86

Antigen presentation mediated by recycling of surface HLA-DR molecules. Nature (1995) 1.85

Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone. J Exp Med (1997) 1.81

Patient-oriented outcome assessment after temporal lobectomy for refractory epilepsy. Neurology (1999) 1.80

Bradycardia during sleep apnea. Characteristics and mechanism. J Clin Invest (1982) 1.74

A prospective, randomized, controlled trial of autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: a position paper. Mult Scler (2012) 1.74

Mixture-based synthetic combinatorial libraries. J Med Chem (1999) 1.74

CD4+CD28- costimulation-independent T cells in multiple sclerosis. J Clin Invest (2001) 1.74

[Nucleotide sequence determination of yeast mitochondrial phenylalanine-tRNA]. C R Acad Sci Hebd Seances Acad Sci D (1978) 1.73

A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis. Brain (2009) 1.69

Declining financial capacity in mild cognitive impairment: A 1-year longitudinal study. Neurology (2009) 1.69

An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humans. J Virol (1994) 1.68

Rotavirus epidemiology in Vellore, south India: group, subgroup, serotype, and electrophoretype. J Clin Microbiol (1988) 1.60

[Age dependence of laboratory parameters in a health study--attempt at calculating a laboratory index for assessing biological aging]. Z Gerontol Geriatr (2002) 1.53

A systematic approach to spinal reconstruction after anterior decompression for neoplastic disease of the thoracic and lumbar spine. Neurosurgery (1993) 1.52

Retroviral marking identifies grafted autologous keratinocytes in porcine wounds receiving cultured epithelium. J Invest Dermatol (1997) 1.52

Estrogen receptor: a prognostic factor in breast cancer. Cancer (1981) 1.51

Effects of nonpathogenic gram-negative bacterium Vitreoscilla filiformis lysate on atopic dermatitis: a prospective, randomized, double-blind, placebo-controlled clinical study. Br J Dermatol (2008) 1.51

Using gadolinium-enhanced magnetic resonance imaging lesions to monitor disease activity in multiple sclerosis. Ann Neurol (1992) 1.50

The use of fibrin glue in skin grafts and tissue-engineered skin replacements: a review. Plast Reconstr Surg (2001) 1.50

Carbon substrate utilization studies of some cultures of Alcaligenes denitrificans, Alcaligenes faecalis, and Alcaligenes odorans isolated from clinical specimens. J Clin Microbiol (1978) 1.48

Atracurium and vecuronium interaction with gentamicin and tobramycin. Can J Anaesth (1989) 1.47

Primary pulmonary hypertension favorable effect of isoproterenol. N Engl J Med (1976) 1.46

Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant (2011) 1.46

Increased serum levels of soluble CD95 (APO-1/Fas) in relapsing-remitting multiple sclerosis. Ann Neurol (1998) 1.45

Complex visual disturbances in Alzheimer's disease. Neurology (1990) 1.45

Relationships among TCR ligand potency, thresholds for effector function elicitation, and the quality of early signaling events in human T cells. J Immunol (1998) 1.44

Use of overpressure to assess the role of bubbles in focused ultrasound lesion shape in vitro. Ultrasound Med Biol (2001) 1.44

Mapping and complementation studies of the gene for release factor 1. J Bacteriol (1986) 1.43

Alpha-1-antitrypsin and a broad spectrum metalloprotease inhibitor, RS113456, have similar acute anti-inflammatory effects. Lab Invest (2001) 1.43

Interactions within the yeast Sm core complex: from proteins to amino acids. Mol Cell Biol (1998) 1.42

Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II. Immunity (2001) 1.42

Demonstration of epidermal transfer from a polymer membrane using genetically marked porcine keratinocytes. Burns (2001) 1.40

[Videolaryngoscopy, for everybody?]. Ann Fr Anesth Reanim (2012) 1.40

Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors. Nat Struct Biol (1999) 1.40

Monitoring the frequency of side effects of drugs. Reasons for stopping drugs could be recorded in general practice. BMJ (1996) 1.39

Effect of macrolides as part of initial empiric therapy on length of stay in patients hospitalized with community-acquired pneumonia. Arch Intern Med (1999) 1.39

Clinical, electrical and mechanical correlations during recovery from neuromuscular blockade with vecuronium. Can J Anaesth (1990) 1.38

Characterization of some groups of gram-negative nonfermentative bacteria by the carbon source alkalinization technique. J Clin Microbiol (1981) 1.37

In vitro activities of 22 beta-lactam antibiotics against penicillin-resistant and penicillin-susceptible viridans group streptococci isolated from blood. Antimicrob Agents Chemother (1995) 1.35

Structural requirements for class I MHC molecule-mediated antigen presentation and cytotoxic T cell recognition of an immunodominant determinant of the human immunodeficiency virus envelope protein. J Exp Med (1989) 1.35

Cryptic peripheral ribosomal domains distributed intermittently along mammalian myelinated axons. J Neurosci (2000) 1.35

Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: relationship to the quality of individual TCR signaling events. J Immunol (1999) 1.34

Evidence-based recommendations for negative pressure wound therapy: treatment variables (pressure levels, wound filler and contact layer)--steps towards an international consensus. J Plast Reconstr Aesthet Surg (2011) 1.33

Ligand motifs of HLA-DRB5*0101 and DRB1*1501 molecules delineated from self-peptides. J Immunol (1994) 1.32

A guide to biological skin substitutes. Br J Plast Surg (2002) 1.32

Human immune responses to synthetic peptides from the Epstein-Barr nuclear antigen. J Immunol (1985) 1.32

In-vitro activity of ciprofloxacin, ceftriaxone and five other antimicrobial agents against 95 strains of Brucella melitensis. J Antimicrob Chemother (1986) 1.32

An epitope in human immunodeficiency virus 1 reverse transcriptase recognized by both mouse and human cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1990) 1.28

Exploring immunological specificity using synthetic peptide combinatorial libraries. Curr Opin Immunol (1999) 1.27

beta-Endorphin: characteristics of binding sites in the rat brain. Biochem Biophys Res Commun (1979) 1.26

Anti-CD47 antibodies promote phagocytosis and inhibit the growth of human myeloma cells. Leukemia (2012) 1.25

Long-term methadone maintenance therapy: effects on liver function. Ann Intern Med (1972) 1.23

Context effects on misreading and suppression at UAG codons in human cells. Mol Cell Biol (1995) 1.22

Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis. Brain (2003) 1.22

Total UK multi-centre experience with a novel arterial occlusion device (Duct Occlud pfm). Heart (1996) 1.22

Combinatorial peptide libraries and biometric score matrices permit the quantitative analysis of specific and degenerate interactions between clonotypic TCR and MHC peptide ligands. J Immunol (2001) 1.21

Clinical features of schizophrenia and linkage to chromosomes 5q, 6p, 8p, and 10p in the Irish Study of High-Density Schizophrenia Families. Am J Psychiatry (2000) 1.21

Autoantibody production in hepatitis B e antigen transgenic mice elicited with a self T-cell peptide and inhibited with nonself peptides. Proc Natl Acad Sci U S A (1991) 1.20