PubRank

S D Shapiro

Author PubWeight™ 138.10‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 1998 9.70
2 Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997 8.19
3 Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J 2003 6.23
4 Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms. J Clin Invest 2000 4.90
5 Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. Nat Med 1999 4.85
6 Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. J Clin Invest 2000 4.16
7 Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. Nat Med 1998 4.04
8 Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice. Proc Natl Acad Sci U S A 1996 2.93
9 Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice. Am J Respir Cell Mol Biol 2000 2.90
10 Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1. Proc Natl Acad Sci U S A 1999 2.80
11 K-ras activation generates an inflammatory response in lung tumors. Oncogene 2006 2.78
12 Human 92- and 72-kilodalton type IV collagenases are elastases. J Biol Chem 1991 2.71
13 Contribution of monocytes/macrophages to compensatory neovascularization: the drilling of metalloelastase-positive tunnels in ischemic myocardium. Circ Res 2000 2.66
14 The serpin alpha1-proteinase inhibitor is a critical substrate for gelatinase B/MMP-9 in vivo. Cell 2000 2.49
15 Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms. J Clin Invest 1998 2.43
16 Interferon gamma induction of pulmonary emphysema in the adult murine lung. J Exp Med 2000 2.36
17 Mechanical ventilation with or without 7-day circuit changes. A randomized controlled trial. Ann Intern Med 1995 2.26
18 Matrix metalloproteinases in lung biology. Respir Res 2000 2.18
19 A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation. Crit Care Med 1997 2.18
20 Hydrolysis of a broad spectrum of extracellular matrix proteins by human macrophage elastase. J Biol Chem 1997 2.00
21 Degradation of outer membrane protein A in Escherichia coli killing by neutrophil elastase. Science 2000 1.97
22 Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme. Proc Natl Acad Sci U S A 1996 1.92
23 Matrix metalloproteinases generate angiostatin: effects on neovascularization. J Immunol 1998 1.87
24 Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy. Nat Med 2001 1.81
25 Elastin degradation by matrix metalloproteinases. Cleavage site specificity and mechanisms of elastolysis. J Biol Chem 1997 1.62
26 Differential expression of matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase genes in the mouse central nervous system in normal and inflammatory states. Am J Pathol 1998 1.60
27 Normal neutrophil function in cathepsin G-deficient mice. Blood 1999 1.53
28 The structural basis for the elastolytic activity of the 92-kDa and 72-kDa gelatinases. Role of the fibronectin type II-like repeats. J Biol Chem 1996 1.53
29 Chronic obstructive pulmonary disease * 3: Experimental animal models of pulmonary emphysema. Thorax 2002 1.51
30 Increase in macrophage elastase (MMP-12) in lungs from patients with chronic obstructive pulmonary disease. Inflamm Res 2005 1.50
31 Differential expression of extracellular matrix remodeling genes in a murine model of bleomycin-induced pulmonary fibrosis. Am J Pathol 1998 1.48
32 End-stage chronic obstructive pulmonary disease: the cigarette is burned out but inflammation rages on. Am J Respir Crit Care Med 2001 1.45
33 Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling. Biochem J 1999 1.45
34 Deletions of the long arm of chromosome 10. Am J Med Genet 1985 1.44
35 Developmental expression of latent transforming growth factor beta binding protein 2 and its requirement early in mouse development. Mol Cell Biol 2000 1.34
36 Neutral proteinases of human mononuclear phagocytes. Cellular differentiation markedly alters cell phenotype for serine proteinases, metalloproteinases, and tissue inhibitor of metalloproteinases. J Immunol 1991 1.34
37 Intraoral findings and anomalies in neonates. Pediatrics 1982 1.32
38 Human macrophage metalloelastase. Genomic organization, chromosomal location, gene linkage, and tissue-specific expression. J Biol Chem 1995 1.30
39 A critical role for neutrophil elastase in experimental bullous pemphigoid. J Clin Invest 2000 1.30
40 Matrix metalloproteinases cleave tissue factor pathway inhibitor. Effects on coagulation. J Biol Chem 2000 1.29
41 The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites. Biochemistry 2001 1.25
42 Patient transport from intensive care increases the risk of developing ventilator-associated pneumonia. Chest 1997 1.23
43 Neurofibromatosis: oral and radiographic manifestations. Oral Surg Oral Med Oral Pathol 1984 1.15
44 Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration. J Invest Dermatol 1999 1.12
45 Proteinase-activated receptor-1 regulation of macrophage elastase (MMP-12) secretion by serine proteinases. J Biol Chem 2000 1.08
46 Prospective study of long-term pulmonary manifestations of mantle irradiation. Int J Radiat Oncol Biol Phys 1990 1.05
47 Deletion 2q: two new cases with karyotypes 46,XY,del(2)(q31q33) and 46,XX,del(2)(q36). J Med Genet 1983 1.05
48 Tricho-dento-osseous syndrome: heterogeneity or clinical variability. Am J Med Genet 1983 1.01
49 Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer. J Invest Dermatol 2000 1.01
50 Polymorphic variation in surfactant protein B is associated with COPD exacerbations. Eur Respir J 2008 0.98
51 A randomized clinical trial comparing an extended-use hygroscopic condenser humidifier with heated-water humidification in mechanically ventilated patients. Chest 1998 0.96
52 Monocyte inflammation augments acrolein-induced Muc5ac expression in mouse lung. Am J Physiol 1999 0.95
53 Molecular cloning, chromosomal location, and tissue-specific expression of the murine cathepsin G gene. Blood 1993 0.95
54 Clinical heterogeneity in the tricho-dento-osseous syndrome. Hum Genet 1983 0.94
55 Heterogeneity in genetic disorders that affect the orofacies. Birth Defects Orig Artic Ser 1983 0.93
56 Efficacy of and patient preference for three counseling formats. J Craniofac Genet Dev Biol 1986 0.93
57 Agenesis of the corpus callosum associated with MASA syndrome. Clin Dysmorphol 1993 0.91
58 Neutral proteinase expression by human mononuclear phagocytes: a prominent role of cellular differentiation. Matrix Suppl 1992 0.90
59 Deficiency of urokinase-type plasminogen activator-mediated plasmin generation impairs vascular remodeling during hypoxia-induced pulmonary hypertension in mice. Circulation 2001 0.90
60 The effect of respiratory therapist-initiated treatment protocols on patient outcomes and resource utilization. Chest 2000 0.90
61 Mechanical ventilation with or without daily changes of in-line suction catheters. Am J Respir Crit Care Med 1997 0.87
62 Genomic organization and chromosomal localization of mouse proteinase 3 (Myeloblastin). Mamm Genome 1999 0.85
63 A potpourri of syndromes with anomalies of dentition. Birth Defects Orig Artic Ser 1983 0.84
64 Substance P and neurokinin-1 receptor expression by intrinsic airway neurons in the rat. Am J Physiol Lung Cell Mol Physiol 2000 0.84
65 Macrophage elastase prevents Gemella morbillorum infection and improves outcome following murine bone marrow transplantation. Chest 1999 0.81
66 Introduction: the matrix metalloproteinase family. Am J Respir Cell Mol Biol 1992 0.81
67 Cartilage proteoglycan degradation by a mouse transformed macrophage cell line is mediated by macrophage metalloelastase. Inflamm Res 1999 0.81
68 Characterization of the mouse neutrophil elastase gene and localization to chromosome 10. Mamm Genome 1997 0.81
69 Macrophage metalloelastase, MMP-12, cleaves human apolipoprotein(a) in the linker region between kringles IV-4 and IV-5. Potential relevance to lipoprotein(a) biology. J Biol Chem 1999 0.80
70 Annexin V decreases PS-mediated macrophage efferocytosis and deteriorates elastase-induced pulmonary emphysema in mice. Am J Physiol Lung Cell Mol Physiol 2012 0.80
71 Involvement of a serine protease, but not of neutrophil elastase, in tumor necrosis factor-induced lethal hepatitis and induction of platelet-activating factor. J Hepatol 2001 0.80
72 Models for gain-of-function and loss-of-function of MMPs. Transgenic and gene targeted mice. Methods Mol Biol 2001 0.80
73 Agonist-induced expression of tissue inhibitor of metalloproteinases and metalloproteinases by human macrophages is regulated by endogenous prostaglandin E2 synthesis. J Invest Dermatol 1995 0.79
74 Brief clinical report: Curry-Hall syndrome. Am J Med Genet 1984 0.78
75 Immature primary molar in the newborn. Pediatr Dent 1983 0.77
76 Mouse macrophage metalloelastase expressed in bacteria absolutely requires zinc for activity. J Biochem 1995 0.77
77 Induction of macrophage matrix metalloproteinase biosynthesis by surfactant protein D. J Biol Chem 2001 0.77
78 Brief clinical report: non-mosaic partial tetrasomy and partial trisomy 9. Am J Med Genet 1985 0.76
79 The prevalence of taurodontism in a select population. J Craniofac Genet Dev Biol 1982 0.76
80 Metastatic retinoblastoma of the maxilla and mandible: report of case. ASDC J Dent Child 1976 0.75
81 Recurrent dislocation of the patella versus generalized joint laxity. Birth Defects Orig Artic Ser 1976 0.75
82 Down's syndrome: significance of the family history. South Med J 1981 0.75
83 A high frequency of structural chromosome abnormalities in a south central texas cytogenetics laboratory. Am J Med Genet 1984 0.75
84 Exclusion of allelism and close linkage between neurofibromatosis and multiple cartilaginous exostoses. Am J Med Genet 1989 0.75
85 Terminal transverse defects with aplasia cutis congenita (Adams-Oliver syndrome). Birth Defects Orig Artic Ser 1985 0.75
86 Studies on facial growth and arch size in cleft lip and palate. J Craniofac Genet Dev Biol 1984 0.75
87 Effect of partial liquid ventilation on pulmonary vascular permeability and edema after experimental acute lung injury. Am J Respir Crit Care Med 2000 0.75
88 Congenital complete atrioventricular block in an infant with Miller-Dieker syndrome. Pediatr Cardiol 1995 0.75
89 A murine model of volutrauma: potential contribution of inflammatory cell proteases to lung injury. Chest 1999 0.75