PubRank

D G Tenen

Author PubWeight™ 141.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Natl Acad Sci U S A 1997 5.44
2 T antigen repression of SV40 early transcription from two promoters. Cell 1981 4.83
3 Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia. Nat Genet 2001 4.79
4 Reversibility of acute B-cell leukaemia induced by BCR-ABL1. Nat Genet 2000 3.67
5 AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia. Nat Med 2001 3.47
6 CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors. Mol Cell Biol 1998 3.19
7 Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. Proc Natl Acad Sci U S A 1999 3.04
8 The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor. Mol Cell Biol 1994 2.69
9 Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene. Nat Genet 1997 2.64
10 CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter. Mol Cell Biol 1996 2.42
11 PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells. Blood 1996 2.35
12 Thermolabile T (tumor) antigen from cells transformed by a temperature-sensitive mutant of simian virus 40. Proc Natl Acad Sci U S A 1975 2.32
13 The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter. J Biol Chem 1993 2.20
14 PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. Blood 2000 2.12
15 Monocyte antigen CD14 is a phospholipid anchored membrane protein. Blood 1989 2.10
16 c-Myc is a critical target for c/EBPalpha in granulopoiesis. Mol Cell Biol 2001 2.10
17 Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model. Blood 2000 1.91
18 Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1). Mol Cell Biol 1994 1.77
19 PU.1 (Spi-1) autoregulates its expression in myeloid cells. Oncogene 1995 1.76
20 Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B. EMBO J 1997 1.73
21 PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation. Immunity 1995 1.72
22 Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells. J Immunol 1992 1.72
23 Secreted phosphoproteins associated with neoplastic transformation: close homology with plasma proteins cleaved during blood coagulation. Cancer Res 1988 1.71
24 PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene. Mol Cell Biol 1995 1.70
25 Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1. Mol Cell Biol 1998 1.69
26 Biological and biochemical studies of cells transformed by simian virus 40 temperature-sensitive gene A mutants and A mutant revertants. J Virol 1977 1.64
27 The CD11b promoter directs high-level expression of reporter genes in macrophages in transgenic mice. Blood 1995 1.61
28 Neutrophils and monocytes express high levels of PU.1 (Spi-1) but not Spi-B. Blood 1995 1.60
29 Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells. Proc Natl Acad Sci U S A 1996 1.51
30 Inhibition of hematopoiesis by competitive binding of transcription factor PU.1. Proc Natl Acad Sci U S A 1994 1.51
31 CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing. Proc Natl Acad Sci U S A 1997 1.50
32 Overcoming limitations of the mRNA differential display technique. Nucleic Acids Res 1995 1.49
33 c-Jun is a JNK-independent coactivator of the PU.1 transcription factor. J Biol Chem 1999 1.49
34 Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation. Mol Cell Biol 2001 1.46
35 Binding of an analog of the simian virus 40 T antigen to wild-type and mutant viral replication origins. J Mol Biol 1982 1.42
36 Acute myelogenous leukemia: current treatment and future directions. Am J Med 1992 1.42
37 Binding of simian virus 40 large T antigen from virus-infected monkey cells to wild-type and mutant viral replication origins. J Mol Biol 1983 1.38
38 The Sp1 transcription factor binds the CD11b promoter specifically in myeloid cells in vivo and is essential for myeloid-specific promoter activity. J Biol Chem 1993 1.38
39 Molecular cloning of the human eosinophil-derived neurotoxin: a member of the ribonuclease gene family. Proc Natl Acad Sci U S A 1989 1.35
40 Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3). J Cell Biol 1988 1.35
41 Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b. Oncogene 2006 1.35
42 Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding. Leukemia 2012 1.35
43 Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin. Biochim Biophys Acta 1989 1.33
44 Differential expression of CD11b/CD18 (Mo1) and myeloperoxidase genes during myeloid differentiation. Blood 1989 1.32
45 Human eosinophil cationic protein. Molecular cloning of a cytotoxin and helminthotoxin with ribonuclease activity. J Exp Med 1989 1.29
46 Regulation of the PU.1 gene by distal elements. Blood 2001 1.28
47 Characterization of the myeloid-specific CD11b promoter. Blood 1992 1.28
48 Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis. Proc Natl Acad Sci U S A 1996 1.28
49 Regulation of CD14 expression during monocytic differentiation induced with 1 alpha,25-dihydroxyvitamin D3. J Immunol 1994 1.24
50 Sp1 is a critical factor for the monocytic specific expression of human CD14. J Biol Chem 1994 1.22
51 Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesis. J Exp Med 1998 1.19
52 Function of PU.1 (Spi-1), C/EBP, and AML1 in early myelopoiesis: regulation of multiple myeloid CSF receptor promoters. Curr Top Microbiol Immunol 1996 1.18
53 Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPα. Oncogene 2011 1.17
54 Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha. Nucleic Acids Res 1998 1.17
55 Monocyte chemoattractant protein-1 gene is expressed in activated neutrophils and retinoic acid-induced human myeloid cell lines. Blood 1994 1.17
56 PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors. Leukemia 2009 1.16
57 Purification of simian virus 40 tumor antigen from a line of simian virus 40-transformed human cells. Proc Natl Acad Sci U S A 1977 1.14
58 Use of a promoterless Renilla luciferase vector as an internal control plasmid for transient co-transfection assays of Ras-mediated transcription activation. Biotechniques 1999 1.13
59 Point mutations impairing cell surface expression of the common beta subunit (CD18) in a patient with leukocyte adhesion molecule (Leu-CAM) deficiency. J Clin Invest 1990 1.12
60 Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains. Mol Cell Biol 1999 1.09
61 Optimization of transient transfection into human myeloid cell lines using a luciferase reporter gene. Exp Hematol 1991 1.09
62 Cellular myosin heavy chain in human leukocytes: isolation of 5' cDNA clones, characterization of the protein, chromosomal localization, and upregulation during myeloid differentiation. Blood 1991 1.08
63 Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML. Leukemia 2010 1.07
64 Structure of the gene encoding CD34, a human hematopoietic stem cell antigen. Genomics 1992 1.06
65 An alternative method for labeling oligonucleotide probes for screening cDNA libraries. Biotechniques 1990 1.03
66 Effect of a stem-loop structure within the SV40 replication origin upon SV40 T antigen binding to origin region sequences. Cell 1983 0.99
67 Octamer binding factors and their coactivator can activate the murine PU.1 (spi-1) promoter. J Biol Chem 1996 0.98
68 PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL. Oncogene 2009 0.93
69 Multiple control elements are required for expression of the human CD34 gene. Gene 1998 0.92
70 Regulation of the gene for CD34, a human hematopoietic stem cell antigen, in KG-1 cells. Blood 1990 0.92
71 Cloning and analysis of the CD18 promoter. Blood 1992 0.90
72 Cooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expression. Oncogene 2007 0.89
73 The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties. Proc Natl Acad Sci U S A 1996 0.88
74 The human CD34 hematopoietic stem cell antigen promoter and a 3' enhancer direct hematopoietic expression in tissue culture. Blood 1992 0.88
75 Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrins. Proc Natl Acad Sci U S A 1988 0.87
76 Molecular cloning and characterization of human eosinophil Charcot-Leyden crystal protein (lysophospholipase). Similarities to IgE binding proteins and the S-type animal lectin superfamily. J Immunol 1993 0.86
77 Identification and characterization of a functional promoter region in the human eosinophil IL-5 receptor alpha subunit gene. J Biol Chem 1995 0.86
78 Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link. Leukemia 2006 0.85
79 A nuclear factor Y (NFY) site positively regulates the human CD34 stem cell gene. Blood 1999 0.85
80 Structural analysis of the CD11b gene and phylogenetic analysis of the alpha-integrin gene family demonstrate remarkable conservation of genomic organization and suggest early diversification during evolution. J Immunol 1993 0.84
81 Two promoters direct expression of the murine Spi-B gene, an Ets family transcription factor. Gene 1998 0.84
82 Characterization of a distinct binding site for the prokaryotic chaperone, GroEL, on a human granulocyte ribonuclease. J Biol Chem 1993 0.82
83 Functional characterization of the promoter for the gene encoding human eosinophil peroxidase. J Biol Chem 1994 0.82
84 Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties. Curr Top Microbiol Immunol 1996 0.81
85 Human immunodeficiency virus-1 infection of the human promyelocytic cell line HL-60: high frequency of low-level infection and effect of subsequent cell differentiation. Blood 1993 0.80
86 Rapid cDNA library screening using the polymerase chain reaction. Biotechniques 1991 0.79
87 The gene for human eosinophil Charcot-Leyden crystal protein directs expression of lysophospholipase activity and spontaneous crystallization in transiently transfected COS cells. J Leukoc Biol 1992 0.79
88 Formation of a cruciform structure at the simian virus 40 replication origin abolishes T-antigen binding to the origin in vitro. J Virol 1985 0.79
89 C/EBPβ promotes BCR-ABL-mediated myeloid expansion and leukemic stem cell exhaustion. Leukemia 2012 0.78
90 Human eosinophil Charcot-Leyden crystal protein: cloning and characterization of a lysophospholipase gene promoter. Blood 1993 0.78
91 Localization of the human eosinophil Charcot-Leyden crystal protein (lysophospholipase) gene (CLC) to chromosome 19 and the human ribonuclease 2 (eosinophil-derived neurotoxin) and ribonuclease 3 (eosinophil cationic protein) genes (RNS2 and RNS3) to chromosome 14. Genomics 1992 0.78
92 Identification of Sp1-binding sites in the CD11c (p150,95 alpha) and CD11a (LFA-1 alpha) integrin subunit promoters and their involvement in the tissue-specific expression of CD11c. Eur J Immunol 1995 0.78
93 Interleukin-5 receptor alpha subunit gene regulation in human eosinophil development: identification of a unique cis-element that acts lie an enhancer in regulating activity of the IL-5R alpha promoter. Curr Top Microbiol Immunol 1996 0.77
94 Analysis of the modulation of transcriptional activity in myelopoiesis and leukemogenesis. Methods 1999 0.77
95 Mutations of the transcription factor PU.1 are not associated with acute lymphoblastic leukaemia. Br J Cancer 2006 0.76
96 Transcriptional regulation of the human eosinophil peroxidase genes: characterization of a peroxidase promoter. Int Arch Allergy Immunol 1994 0.76
97 Multiple sclerosis: getting personal with induced pluripotent stem cells. Cell Death Dis 2016 0.75
98 Functional characterization of the promoter for the gene encoding murine CD34. Biochim Biophys Acta 1997 0.75