Published in RNA on August 01, 1998
Escherichia coli Hfq has distinct interaction surfaces for DsrA, rpoS and poly(A) RNAs. Nat Struct Mol Biol (2004) 2.79
Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity. EMBO J (2003) 2.47
RNA catalysis in model protocell vesicles. J Am Chem Soc (2005) 1.70
Ribozyme speed limits. RNA (2003) 1.68
Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations. RNA (2001) 1.51
The hammerhead cleavage reaction in monovalent cations. RNA (2001) 1.44
The global structure of the VS ribozyme. EMBO J (2002) 1.34
Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction. EMBO J (2001) 1.30
Hammerhead-mediated processing of satellite pDo500 family transcripts from Dolichopoda cave crickets. Nucleic Acids Res (2000) 1.27
Functional hammerhead ribozymes naturally encoded in the genome of Arabidopsis thaliana. Plant Cell (2005) 1.26
Hammerhead redux: does the new structure fit the old biochemical data? RNA (2008) 1.25
Recent advances in the elucidation of the mechanisms of action of ribozymes. Nucleic Acids Res (2001) 1.23
RNA catalysis through compartmentalization. Nat Chem (2012) 1.20
A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiency. Proc Natl Acad Sci U S A (1999) 1.20
High-performance liquid chromatography purification of homogenous-length RNA produced by trans cleavage with a hammerhead ribozyme. RNA (1999) 1.18
Entropy-driven folding of an RNA helical junction: an isothermal titration calorimetric analysis of the hammerhead ribozyme. Biochemistry (2004) 1.14
Fast ribozyme cleavage releases transcripts from RNA polymerase II and aborts co-transcriptional pre-mRNA processing. Nat Struct Mol Biol (2009) 1.12
From alpaca to zebrafish: hammerhead ribozymes wherever you look. RNA (2010) 1.07
Minimal and extended hammerheads utilize a similar dynamic reaction mechanism for catalysis. RNA (2007) 1.04
Efficient ligation of the Schistosoma hammerhead ribozyme. Biochemistry (2007) 1.04
The tolerance to exchanges of the Watson Crick base pair in the hammerhead ribozyme core is determined by surrounding elements. RNA (2007) 1.03
Engineered allosteric ribozymes that respond to specific divalent metal ions. Nucleic Acids Res (2005) 1.01
Catalytic diversity of extended hammerhead ribozymes. Biochemistry (2008) 0.99
A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation. RNA (2001) 0.98
Structure-function analysis of the ribozymes of chrysanthemum chlorotic mottle viroid: a loop-loop interaction motif conserved in most natural hammerheads. Nucleic Acids Res (2008) 0.96
Long-range tertiary interactions in single hammerhead ribozymes bias motional sampling toward catalytically active conformations. RNA (2010) 0.95
Substrate specificity and reaction kinetics of an X-motif ribozyme. RNA (2003) 0.94
Multiple conformational states of the hammerhead ribozyme, broad time range of relaxation and topology of dynamics. Nucleic Acids Res (2000) 0.90
Rapid kinetic characterization of hammerhead ribozymes by real-time monitoring of fluorescence resonance energy transfer (FRET). RNA (1999) 0.89
Catalytic cleavage of cis- and trans-acting antigenomic delta ribozymes in the presence of various divalent metal ions. Nucleic Acids Res (2001) 0.88
A continuous kinetic assay for RNA-cleaving deoxyribozymes, exploiting ethidium bromide as an extrinsic fluorescent probe. Nucleic Acids Res (2002) 0.87
Stochastic simulations of minimal cells: the Ribocell model. BMC Bioinformatics (2012) 0.86
Importance in catalysis of a magnesium ion with very low affinity for a hammerhead ribozyme. Nucleic Acids Res (2004) 0.86
Cleavage of model substrates by archaeal RNase P: role of protein cofactors in cleavage-site selection. Nucleic Acids Res (2010) 0.85
DNAzyme-mediated catalysis with only guanosine and cytidine nucleotides. Nucleic Acids Res (2008) 0.85
Cryoenzymology of the hammerhead ribozyme. RNA (1998) 0.84
A modular, bifunctional RNA that integrates itself into a target RNA. Proc Natl Acad Sci U S A (2003) 0.84
Rapid NMR screening of RNA secondary structure and binding. J Biomol NMR (2015) 0.84
The virtues of self-binding: high sequence specificity for RNA cleavage by self-processed hammerhead ribozymes. Nucleic Acids Res (2000) 0.83
Using droplet-based microfluidics to improve the catalytic properties of RNA under multiple-turnover conditions. RNA (2015) 0.82
The hammerhead ribozyme: structure, catalysis, and gene regulation. Prog Mol Biol Transl Sci (2013) 0.82
A versatile cis-blocking and trans-activation strategy for ribozyme characterization. Nucleic Acids Res (2012) 0.82
Efficient trans-cleavage by the Schistosoma mansoni SMalpha1 hammerhead ribozyme in the extreme thermophile Thermus thermophilus. Nucleic Acids Res (2002) 0.81
Expanded hammerhead ribozymes containing addressable three-way junctions. RNA (2009) 0.81
Development of lead hammerhead ribozyme candidates against human rod opsin mRNA for retinal degeneration therapy. Exp Eye Res (2008) 0.80
Measurements of weak interactions between truncated substrates and a hammerhead ribozyme by competitive kinetic analyses: implications for the design of new and efficient ribozymes with high sequence specificity. Nucleic Acids Res (2002) 0.79
Structural and catalytic effects of an invariant purine substitution in the hammerhead ribozyme: implications for the mechanism of acid-base catalysis. Acta Crystallogr D Biol Crystallogr (2014) 0.79
Bottlenecks in development of retinal therapeutic post-transcriptional gene silencing agents. Vision Res (2007) 0.79
Hammerhead ribozyme activity and oligonucleotide duplex stability in mixed solutions of water and organic compounds. FEBS Open Bio (2014) 0.78
The role of phosphate groups in the VS ribozyme-substrate interaction. Nucleic Acids Res (2004) 0.78
Trans-cleaving hammerhead ribozymes with tertiary stabilizing motifs: in vitro and in vivo activity against a structured viroid RNA. Nucleic Acids Res (2010) 0.78
Cleavage mediated by the P15 domain of bacterial RNase P RNA. Nucleic Acids Res (2011) 0.78
Determination of hepatitis delta virus ribozyme N(-1) nucleobase and functional group specificity using internal competition kinetics. Anal Biochem (2015) 0.77
Minimal Hammerhead Ribozymes with Uncompromised Catalytic Activity. J Mol Biol (2015) 0.77
Variables and strategies in development of therapeutic post-transcriptional gene silencing agents. J Ophthalmol (2011) 0.76
Ligation of RNA Oligomers by the Schistosoma mansoni Hammerhead Ribozyme in Frozen Solution. J Mol Evol (2016) 0.75
Transition-state stabilization in Escherichia coli ribonuclease P RNA-mediated cleavage of model substrates. Nucleic Acids Res (2013) 0.75
Conformational heterogeneity and the determinants of tertiary stabilization in the hammerhead ribozyme from Dolichopoda cave crickets. RNA Biol (2011) 0.75
Dangerous play--splitting the message may leave you empty handed. Nat Struct Mol Biol (2009) 0.75
G17-modified hammerhead ribozymes are active in vitro and in vivo. RNA (2013) 0.75
Effects of Pathogenic Variations in the Human Rhodopsin Gene (hRHO) on the Predicted Accessibility for a Lead Candidate Ribozyme. Invest Ophthalmol Vis Sci (2017) 0.75
Simple RNA enzymes with new and highly specific endoribonuclease activities. Nature (1988) 8.74
A small catalytic oligoribonucleotide. Nature (1987) 8.73
Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites. Cell (1987) 8.19
Three-dimensional structure of a hammerhead ribozyme. Nature (1994) 7.14
RNA structure prediction. Annu Rev Biophys Biophys Chem (1988) 5.75
RNA chaperones and the RNA folding problem. J Biol Chem (1995) 5.67
Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid. Nucleic Acids Res (1986) 5.59
Co-operative non-enzymic base recognition. 3. Kinetics of the helix-coil transition of the oligoribouridylic--oligoriboadenylic acid system and of oligoriboadenylic acid alone at acidic pH. J Mol Biol (1971) 5.02
The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage. Cell (1995) 4.79
Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site. Cell (1987) 4.08
A DNA enzyme that cleaves RNA. Chem Biol (1994) 3.88
Predicting thermodynamic properties of RNA. Methods Enzymol (1995) 3.38
Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry (1991) 3.31
An RNA chaperone activity of non-specific RNA binding proteins in hammerhead ribozyme catalysis. EMBO J (1994) 2.96
Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism. Biochemistry (1993) 2.91
Substrate sequence effects on "hammerhead" RNA catalytic efficiency. Proc Natl Acad Sci U S A (1990) 2.81
Kinetics of intermolecular cleavage by hammerhead ribozymes. Biochemistry (1992) 2.79
Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site. Biochemistry (1990) 2.77
Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science (1996) 2.77
Numbering system for the hammerhead. Nucleic Acids Res (1992) 2.74
Configurationally defined phosphorothioate-containing oligoribonucleotides in the study of the mechanism of cleavage of hammerhead ribozymes. Nucleic Acids Res (1991) 2.72
A kinetic and thermodynamic framework for the hammerhead ribozyme reaction. Biochemistry (1994) 2.39
Self-cleavage of RNA in the replication of small pathogens of plants and animals. Trends Biochem Sci (1989) 2.17
A DNA enzyme with Mg(2+)-dependent RNA phosphoesterase activity. Chem Biol (1995) 2.16
Laser temperature-jump, spectroscopic, and thermodynamic study of salt effects on duplex formation by dGCATGC. Biochemistry (1989) 2.13
Implications of ribozyme kinetics for targeting the cleavage of specific RNA molecules in vivo: more isn't always better. Proc Natl Acad Sci U S A (1991) 2.09
Protein enhancement of hammerhead ribozyme catalysis. Science (1993) 2.08
Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding. Biochemistry (1991) 2.08
Cleavage of specific sites of RNA by designed ribozymes. FEBS Lett (1988) 2.05
Efficient trans-cleavage of a stem-loop RNA substrate by a ribozyme derived from neurospora VS RNA. EMBO J (1995) 1.99
The structure, function and application of the hammerhead ribozyme. Eur J Biochem (1997) 1.94
A catalytic 13-mer ribozyme. Nucleic Acids Res (1989) 1.82
Structure and function of the hammerhead ribozyme: an unfinished story. RNA (1996) 1.79
Relationship between 2'-hydroxyls and magnesium binding in the hammerhead RNA domain: a model for ribozyme catalysis. Biochemistry (1991) 1.75
A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements. Science (1994) 1.71
Inhibition of the hammerhead ribozyme cleavage reaction by site-specific binding of Tb. Science (1998) 1.66
Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 2. Kinetic description of the reaction of an RNA substrate that forms a mismatch at the active site. Biochemistry (1990) 1.63
Building a kinetic framework for group II intron ribozyme activity: quantitation of interdomain binding and reaction rate. Biochemistry (1994) 1.61
A kinetic mechanism for cleavage of precursor tRNA(Asp) catalyzed by the RNA component of Bacillus subtilis ribonuclease P. Biochemistry (1994) 1.60
Kinetics and thermodynamics of intermolecular catalysis by hairpin ribozymes. Biochemistry (1995) 1.58
Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation. J Biol Chem (1997) 1.55
Studies on the hammerhead RNA self-cleaving domain. Gene (1989) 1.52
Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain. Biochemistry (1992) 1.52
Minimal sequence requirements for ribozyme activity. Proc Natl Acad Sci U S A (1992) 1.50
Specificity of hammerhead ribozyme cleavage. EMBO J (1996) 1.49
Sequence-dependent structural variations of hammerhead RNA enzymes. Nucleic Acids Res (1990) 1.47
Design of RNA enzymes distinguishing a single base mutation in RNA. Nucleic Acids Res (1989) 1.46
Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1. J Biol Chem (1992) 1.45
Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages. Nucleic Acids Res (1993) 1.44
Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions. Proc Natl Acad Sci U S A (1994) 1.42
Function of specific 2'-hydroxyl groups of guanosines in a hammerhead ribozyme probed by 2' modifications. Proc Natl Acad Sci U S A (1992) 1.41
Mg(2+)-dependent conformational changes in the hammerhead ribozyme. Biochemistry (1996) 1.40
The effect of base mismatches in the substrate recognition helices of hammerhead ribozymes on binding and catalysis. Nucleic Acids Res (1995) 1.39
Self-cleaving catalytic RNA. FASEB J (1993) 1.39
Nuclease resistant ribozymes with high catalytic activity. EMBO J (1992) 1.38
The hammerhead RNA domain, a model ribozyme. Biochim Biophys Acta (1993) 1.37
Ionic interactions and the global conformations of the hammerhead ribozyme. Nat Struct Biol (1995) 1.36
Ribozymes as human therapeutic agents. J Med Chem (1995) 1.36
Mixed DNA/RNA polymers are cleaved by the hammerhead ribozyme. Biochemistry (1990) 1.35
Ionic requirements for RNA binding, cleavage, and ligation by the hairpin ribozyme. Biochemistry (1993) 1.30
Comparison of the kinetics of ribooligonucleotide, deoxyribooligonucleotide, and hybrid oligonucleotide double-strand formation by temperature-jump kinetics. Biochemistry (1982) 1.29
Generality of the NUX rule: kinetic analysis of the results of systematic mutations in the trinucleotide at the cleavage site of hammerhead ribozymes. Biochemistry (1995) 1.26
Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo. Nucleic Acids Res (1992) 1.24
Controlled, targeted, intracellular expression of ribozymes: progress and problems. Trends Biotechnol (1995) 1.20
Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases. Proc Natl Acad Sci U S A (1996) 1.18
Probing RNA tertiary structure: interhelical crosslinking of the hammerhead ribozyme. RNA (1995) 1.17
The ion-induced folding of the hammerhead ribozyme: core sequence changes that perturb folding into the active conformation. RNA (1996) 1.16
Importance of specific purine amino and hydroxyl groups for efficient cleavage by a hammerhead ribozyme. Proc Natl Acad Sci U S A (1992) 1.12
Global conformation of a self-cleaving hammerhead RNA. Biochemistry (1994) 1.07
Use of intrinsic binding energy for catalysis by an RNA enzyme. Proc Natl Acad Sci U S A (1997) 1.06
Chemically modified hammerhead ribozymes with improved catalytic rates. Biochemistry (1996) 1.03
Kinetic characterization of two I/II format hammerhead ribozymes. RNA (1996) 1.03
The synthesis of oligoribonucleotides containing O6-methylguanosine: the role of conserved guanosine residues in hammerhead ribozyme cleavage. Nucleic Acids Res (1993) 1.02
Fluorescence resonance energy transfer analysis of ribozyme kinetics reveals the mode of action of a facilitator oligonucleotide. Biochemistry (1996) 1.01
A comparison of the in vitro activity of DNA-armed and all-RNA hammerhead ribozymes. Nucleic Acids Res (1995) 1.01
The role of the exocyclic amino groups of conserved purines in hammerhead ribozyme cleavage. Biochem Biophys Res Commun (1992) 1.00
Temperature-dependent change in the rate-determining step in a reaction catalyzed by a hammerhead ribozyme. FEBS Lett (1995) 0.99
A ribozyme with DNA in the hybridising arms displays enhanced cleavage ability. Nucleic Acids Res (1992) 0.99
The internal equilibrium of the hammerhead ribozyme reaction. Biochemistry (1995) 0.99
Enhancement of ribozyme catalytic activity by a contiguous oligodeoxynucleotide (facilitator) and by 2'-O-methylation. Nucleic Acids Res (1992) 0.98
Unexpected anisotropy in substrate cleavage rates by asymmetric hammerhead ribozymes. Nucleic Acids Res (1996) 0.97
Cleavage of full-length beta APP mRNA by hammerhead ribozymes. Nucleic Acids Res (1993) 0.95
Constructing an efficient trans-acting genomic HDV ribozyme. FEBS Lett (1996) 0.95
The subcellular localization and length of hammerhead ribozymes determine efficacy in human cells. Nucleic Acids Res (1997) 0.93
Multiple folded conformations of a hammerhead ribozyme domain under cleavage conditions. J Mol Biol (1994) 0.93
Extension of helix II of an HIV-1-directed hammerhead ribozyme with long antisense flanks does not alter kinetic parameters in vitro but causes loss of the inhibitory potential in living cells. Nucleic Acids Res (1994) 0.90
RNA cleavage by small catalytic RNAs. Curr Opin Struct Biol (1995) 0.89
Oligonucleotide facilitators may inhibit or activate a hammerhead ribozyme. Nucleic Acids Res (1996) 0.89
In vitro activity of minimised hammerhead ribozymes. Nucleic Acids Res (1995) 0.87
Hammerhead ribozyme engineering. Curr Opin Struct Biol (1996) 0.86
Probing the hammerhead ribozyme structure with ribonucleases. Nucleic Acids Res (1994) 0.85
Activity of the hammerhead ribozyme upon inversion of the stereocenters for the guanosine 2'-hydroxyls. Biochemistry (1994) 0.84
An oligodeoxyribonucleotide that supports catalytic activity in the hammerhead ribozyme domain. Nucleic Acids Res (1995) 0.83
Divalent metal ions and the internal equilibrium of the hammerhead ribozyme. Biochemistry (1995) 0.82
Catalytic activity and stability of hammerhead ribozymes containing 2'-acetamido-2'-deoxyribonucleosides. Biochem Biophys Res Commun (1995) 0.81
Relating conformation, Mg2+ binding, and functional group modification in the hammerhead ribozyme. RNA (1997) 0.81
An ultraviolet crosslink in the hammerhead ribozyme dependent on 2-thiocytidine or 4-thiouridine substitution. Nucleic Acids Res (1997) 0.78
Similar cleavage efficiencies of an oligoribonucleotide substrate and an mdr1 mRNA segment by a hammerhead ribozyme. Gene (1995) 0.78
Myositis Ossificans (Juvenile Progressive Type). Proc R Soc Med (1915) 0.77
Improved estimation of secondary structure in ribonucleic acids. Nat New Biol (1973) 46.33
Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates. Nucleic Acids Res (1987) 25.34
Estimation of secondary structure in ribonucleic acids. Nature (1971) 20.52
Stability of ribonucleic acid double-stranded helices. J Mol Biol (1974) 16.35
Synthesis of small RNAs using T7 RNA polymerase. Methods Enzymol (1989) 10.82
3'-terminal labelling of RNA with T4 RNA ligase. Nature (1978) 10.69
A small catalytic oligoribonucleotide. Nature (1987) 8.73
Stability of RNA hairpin loops: A 6 -C m -U 6 . J Mol Biol (1973) 8.39
Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro. Proc Natl Acad Sci U S A (1988) 7.76
Specific labeling of 3' termini of RNA with T4 RNA ligase. Methods Enzymol (1980) 7.55
Reactions at the termini of tRNA with T4 RNA ligase. Nucleic Acids Res (1978) 5.93
CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes. Proc Natl Acad Sci U S A (1988) 5.50
Self-complementary oligoribonucleotides: effects of helix defects and guanylic acid-cytidylic acid base pairs. J Mol Biol (1971) 4.54
RNA binding site of R17 coat protein. Biochemistry (1987) 4.20
Sequence-specific interaction of R17 coat protein with its ribonucleic acid binding site. Biochemistry (1983) 4.09
Enzymatic oligoribonucleotide synthesis with T4 RNA ligase. Biochemistry (1978) 3.99
3'-Phosphatase activity in T4 polynucleotide kinase. Biochemistry (1977) 3.86
Sequence requirements of the hammerhead RNA self-cleavage reaction. Biochemistry (1990) 3.64
Uniform binding of aminoacyl-tRNAs to elongation factor Tu by thermodynamic compensation. Science (2001) 3.54
Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry (1991) 3.31
Characterization of RNA hairpin loop stability. Nucleic Acids Res (1988) 3.10
Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism. Biochemistry (1993) 2.91
Specific interaction between RNA phage coat proteins and RNA. Prog Nucleic Acid Res Mol Biol (1991) 2.84
T4-induced RNA ligase joins single-stranded oligoribonucleotides. Proc Natl Acad Sci U S A (1975) 2.84
Substrate sequence effects on "hammerhead" RNA catalytic efficiency. Proc Natl Acad Sci U S A (1990) 2.81
Kinetics of intermolecular cleavage by hammerhead ribozymes. Biochemistry (1992) 2.79
Self-complementary oligoribonucleotides: adenylic acid-uridylic acid block copolymers. J Mol Biol (1971) 2.78
Numbering system for the hammerhead. Nucleic Acids Res (1992) 2.74
In vitro selection of RNAs that undergo autolytic cleavage with Pb2+. Biochemistry (1992) 2.60
Role of a bulged A residue in a specific RNA-protein interaction. Biochemistry (1987) 2.52
A kinetic and thermodynamic framework for the hammerhead ribozyme reaction. Biochemistry (1994) 2.39
T7 RNA polymerase produces 5' end heterogeneity during in vitro transcription from certain templates. RNA (1998) 2.39
Nucleotides in yeast tRNAPhe required for the specific recognition by its cognate synthetase. Science (1989) 2.36
Equimolar addition of oligoribonucleotides with T4 RNA ligase. Nucleic Acids Res (1977) 2.32
Interaction of R17 coat protein with synthetic variants of its ribonucleic acid binding site. Biochemistry (1983) 2.30
An RNA mutation that increases the affinity of an RNA-protein interaction. Nucleic Acids Res (1987) 2.25
Quantitative in situ hybridization of ribosomal RNA species to polytene chromosomes of Drosophila melanogaster. J Mol Biol (1977) 2.18
Folding of circularly permuted transfer RNAs. Science (1991) 2.14
Complementary oligonucleotide binding to the anticodon loop of fMet-transfer RNA. Nature (1970) 2.13
Kinetic and thermodynamic characterization of the R17 coat protein-ribonucleic acid interaction. Biochemistry (1983) 2.07
Ribonucleoprotein complexes of R17 coat protein and a translational operator analog. J Mol Biol (1988) 1.99
RNA template-directed RNA synthesis by T7 RNA polymerase. Proc Natl Acad Sci U S A (1994) 1.98
Dinucleoside pyrophosphate are substrates for T4-induced RNA ligase. Proc Natl Acad Sci U S A (1977) 1.94
Enzymatic replacement of the anticodon of yeast phenylalanine transfer ribonucleic acid. Biochemistry (1982) 1.94
Lead-catalyzed cleavage of yeast tRNAPhe mutants. Biochemistry (1990) 1.87
Tetraloops and RNA folding. Nature (1990) 1.87
Chemical and enzymatic synthesis of tRNAs for high-throughput crystallization. RNA (2001) 1.81
Thiophosphate interference experiments locate phosphates important for the hammerhead RNA self-cleavage reaction. Nucleic Acids Res (1990) 1.76
Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins. Science (1993) 1.73
Mutants of the bacteriophage MS2 coat protein that alter its cooperative binding to RNA. Biochemistry (1995) 1.72
Structure of an unmodified tRNA molecule. Biochemistry (1989) 1.71
Inhibition of the hammerhead ribozyme cleavage reaction by site-specific binding of Tb. Science (1998) 1.66
Synthesis of modified nucleoside 3',5'-bisphosphates and their incorporation into oligoribonucleotides with T4 RNA ligase. Biochemistry (1978) 1.62
Joining of RNA molecules with RNA ligase. Methods Enzymol (1983) 1.62
Nucleoside and nucleotide inactivation of R17 coat protein: evidence for a transient covalent RNA-protein bond. Biochemistry (1985) 1.62
Role of the tertiary nucleotides in the interaction of yeast phenylalanine tRNA with its cognate synthetase. Biochemistry (1990) 1.60
Determination of RNA-protein contacts using thiophosphate substitutions. Biochemistry (1989) 1.60
The self-splicing RNA of Tetrahymena is trapped in a less active conformation by gel purification. Biochemistry (1990) 1.58
Escherichia coli DbpA is an RNA helicase that requires hairpin 92 of 23S rRNA. EMBO J (2001) 1.58
Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation. J Biol Chem (1997) 1.55
Studies on the hammerhead RNA self-cleaving domain. Gene (1989) 1.52
Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations. RNA (2001) 1.51
Specificity of hammerhead ribozyme cleavage. EMBO J (1996) 1.49
Complementary oligonucleotide binding to transfer RNA. J Mol Biol (1972) 1.49
Sequence-dependent structural variations of hammerhead RNA enzymes. Nucleic Acids Res (1990) 1.47
Proton NMR and structural features of a 24-nucleotide RNA hairpin. Biochemistry (1995) 1.47
Intact aminoacyl-tRNA is required to trigger GTP hydrolysis by elongation factor Tu on the ribosome. Biochemistry (2000) 1.47
A small metalloribozyme with a two-step mechanism. Nature (1992) 1.46
Specific RNA binding by Q beta coat protein. Biochemistry (1989) 1.45
Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletions. Proc Natl Acad Sci U S A (1994) 1.42
Roles of operator and non-operator RNA sequences in bacteriophage R17 capsid assembly. J Mol Biol (1988) 1.41
The Escherichia coli DEAD protein DbpA recognizes a small RNA hairpin in 23S rRNA. RNA (2001) 1.40
In vitro analysis of translational rate and accuracy with an unmodified tRNA. Biochemistry (1993) 1.40
A thermodynamic analysis of the sequence-specific binding of RNA by bacteriophage MS2 coat protein. Proc Natl Acad Sci U S A (1998) 1.40
The effect of base mismatches in the substrate recognition helices of hammerhead ribozymes on binding and catalysis. Nucleic Acids Res (1995) 1.39
Self-cleaving catalytic RNA. FASEB J (1993) 1.39
Cloning and biochemical characterization of Bacillus subtilis YxiN, a DEAD protein specifically activated by 23S rRNA: delineation of a novel sub-family of bacterial DEAD proteins. Nucleic Acids Res (1999) 1.35
A specific, UV-induced RNA-protein cross-link using 5-bromouridine-substituted RNA. Biochemistry (1991) 1.34
Specific interaction of anticodon loop residues with yeast phenylalanyl-tRNA synthetase. Biochemistry (1982) 1.32
Enzymatic synthesis of a 21-nucleotide coat protein binding fragment of R17 ribonucleic acid. Biochemistry (1982) 1.31
Determination of recognition nucleotides for Escherichia coli phenylalanyl-tRNA synthetase. Biochemistry (1992) 1.31
Inhibition of the hammerhead ribozyme by neomycin. RNA (1995) 1.31
Cooperative binding of R17 coat protein to RNA. Biochemistry (1990) 1.30
Quantitative assessment of EF-1alpha.GTP binding to aminoacyl-tRNAs, aminoacyl-viral RNA, and tRNA shows close correspondence to the RNA binding properties of EF-Tu. J Biol Chem (1999) 1.29
Kinetic analysis of the RNA-dependent adenosinetriphosphatase activity of DbpA, an Escherichia coli DEAD protein specific for 23S ribosomal RNA. Biochemistry (1998) 1.28
Binding of yeast tRNAPhe anticodon arm to Escherichia coli 30 S ribosomes. J Mol Biol (1983) 1.27
Polynucleotide kinase from a T4 mutant which lacks the 3' phosphatase activity. Nucleic Acids Res (1978) 1.27
Properties of an in vitro selected Pb2+ cleavage motif. Biochemistry (1994) 1.27
Guanosine modifications in runoff transcripts of synthetic transfer RNA-Phe genes microinjected into Xenopus oocytes. Biochim Biophys Acta (1990) 1.25
Hammerhead ribozymes with a faster cleavage rate. Biochemistry (1997) 1.25
Many of the conserved nucleotides of tRNA(Phe) are not essential for ternary complex formation and peptide elongation. EMBO J (1994) 1.24
Interaction of Escherichia coli host factor protein with oligoriboadenylates. Biochemistry (1980) 1.21
Aminoacylation of anticodon loop substituted yeast tyrosine transfer RNA. Biochemistry (1985) 1.20
A re-investigation of the thio effect at the hammerhead cleavage site. Nucleic Acids Res (1999) 1.20
A new assay for tRNA aminoacylation kinetics. RNA (1998) 1.19
Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX. Nucleic Acids Res (2000) 1.19
Effect of replacing uridine 33 in yeast tRNAPhe on the reaction with ribosomes. J Biol Chem (1986) 1.17
The role of 2'-hydroxyl groups in an RNA-protein interaction. Biochemistry (1995) 1.15
Identification of thermodynamically relevant interactions between EF-Tu and backbone elements of tRNA. J Mol Biol (2001) 1.13
Recognition of yeast tRNA(Phe) by its cognate yeast phenylalanyl-tRNA synthetase: an analysis of specificity. Biochemistry (1992) 1.12