Published in J Immunol on September 01, 1998
Adoptive-cell-transfer therapy for the treatment of patients with cancer. Nat Rev Cancer (2003) 4.99
A2A adenosine receptor protects tumors from antitumor T cells. Proc Natl Acad Sci U S A (2006) 4.25
Immune surveillance against a solid tumor fails because of immunological ignorance. Proc Natl Acad Sci U S A (1999) 2.19
Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication. Immunol Rev (2011) 2.02
Tumor masses support naive T cell infiltration, activation, and differentiation into effectors. J Exp Med (2010) 1.97
Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo. Cancer Res (2004) 1.74
Suppression of proximal T cell receptor signaling and lytic function in CD8+ tumor-infiltrating T cells. Cancer Res (2007) 1.58
CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens. J Exp Med (2004) 1.56
Tumor growth enhances cross-presentation leading to limited T cell activation without tolerance. J Exp Med (2002) 1.48
Autoimmunity and the immunotherapy of cancer: targeting the "self" to destroy the "other". Crit Rev Immunol (2000) 1.47
Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity. Nat Med (2010) 1.45
Control of the immune response by pro-angiogenic factors. Front Oncol (2014) 1.26
Intensity of the vaccine-elicited immune response determines tumor clearance. J Immunol (2002) 1.07
The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells. Proc Natl Acad Sci U S A (2014) 1.01
IL4I1: an inhibitor of the CD8⁺ antitumor T-cell response in vivo. Eur J Immunol (2011) 0.98
Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion. EMBO J (2015) 0.96
CD4+ T cell-derived IL-2 signals during early priming advances primary CD8+ T cell responses. PLoS One (2009) 0.93
Human melanoma-specific CD8(+) T-cells from metastases are capable of antigen-specific degranulation and cytolysis directly ex vivo. Oncoimmunology (2012) 0.92
Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity. MBio (2010) 0.88
Generation and functional assessment of antigen-specific T cells stimulated by fusions of dendritic cells and allogeneic breast cancer cells. Vaccine (2007) 0.85
The strength of the T cell response against a surrogate tumor antigen induced by oncolytic VSV therapy does not correlate with tumor control. Mol Ther (2014) 0.85
IFNγ producing CD8(+) T cells modified to resist major immune checkpoints induce regression of MHC class I-deficient melanomas. Oncoimmunology (2015) 0.84
RNAi-mediated TCR knockdown prevents autoimmunity in mice caused by mixed TCR dimers following TCR gene transfer. Mol Ther (2014) 0.83
How Informative is the Immune Response Against Surrogate Tumor Antigens to Assess Antitumor Immunity? Front Oncol (2014) 0.80
A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion. Nat Commun (2016) 0.79
Efficiency of dendritic cell vaccination against B16 melanoma depends on the immunization route. PLoS One (2014) 0.79
The availability of a functional tumor targeting T-cell repertoire determines the anti-tumor efficiency of combination therapy with anti-CTLA-4 and anti-4-1BB antibodies. PLoS One (2013) 0.79
CD8 engineered cytotoxic T cells reprogram melanoma tumor environment. Oncoimmunology (2015) 0.78
Quantification of B16 melanoma cells in lungs using triplex Q-PCR--a new approach to evaluate melanoma cell metastasis and tumor control. PLoS One (2014) 0.77
The innate immune system recognizes and regulates major histocompatibility complex class I (MHCI) expression on MHCIlow tumor cells. Cancer Immun (2008) 0.77
Co-expression of tumor antigen and interleukin-2 from an adenoviral vector augments the efficiency of therapeutic tumor vaccination. Mol Ther (2014) 0.76
Dendritic cell-specific delivery of Flt3L by coronavirus vectors secures induction of therapeutic antitumor immunity. PLoS One (2013) 0.76
Impaired access of lymphocytes to neoplastic prostate tissue is associated with neoangiogenesis in the tumour site. Br J Cancer (2007) 0.75
Defects in the acquisition of tumor-killing capability of CD8+ cytotoxic T cells in streptozotocin-induced diabetic mice. PLoS One (2014) 0.75
Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory. J Immunol (2016) 0.75
Stimulation of autoimmunity by toll-like receptor ligands. Ann Rheum Dis (2005) 0.75
Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature (1993) 9.81
Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell (1991) 6.49
Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts. J Exp Med (1996) 3.26
Viral infections induce abundant numbers of senescent CD8 T cells. J Immunol (2001) 3.04
On the role of antigen in maintaining cytotoxic T-cell memory. Proc Natl Acad Sci U S A (1996) 2.55
T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides. Eur J Immunol (1993) 2.25
T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes. J Exp Med (1986) 2.20
Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity (2000) 2.17
Kinetics of the response of naive and memory CD8 T cells to antigen: similarities and differences. Eur J Immunol (1999) 2.12
T cell priming versus T cell tolerance induced by synthetic peptides. J Exp Med (1995) 2.07
Viral and bacterial infections interfere with peripheral tolerance induction and activate CD8+ T cells to cause immunopathology. J Exp Med (1998) 1.70
Effector T-cell induction and T-cell memory versus peripheral deletion of T cells. Immunol Rev (1993) 1.61
Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities. Nature (1990) 1.61
Metastatic melanoma of unknown primary origin shows prognostic similarities to regional metastatic melanoma: recommendations for initial staging examinations. Cancer (1997) 1.59
Virus-specific CD8+ cells can switch to interleukin 5 production and induce airway eosinophilia. J Exp Med (1995) 1.58
Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha. J Immunol (1993) 1.55
N-desmethyldiazepam and amylobarbitone sodium as hypnotics in anxious patients. Plasma levels, clinical efficacy and residual effects. Psychopharmacologia (1975) 1.54
Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition. Eur J Immunol (1991) 1.47
T-cell reactivity and tolerance to Mlsa-encoded antigens. Immunol Rev (1989) 1.45
Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression. Proc Natl Acad Sci U S A (1992) 1.43
Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness. Proc Natl Acad Sci U S A (1994) 1.43
T cell receptor variable gene usage in a specific cytotoxic T cell response. Primary structure of the antigen-MHC receptor of four hapten-specific cytotoxic T cell clones. J Exp Med (1987) 1.39
Effect of rabbit anti-asialo GM1 treatment in vivo or with anti-asialo GM1 plus complement in vitro on cytotoxic T cell activities. J Immunol (1986) 1.39
Peptide antigen treatment of naive and virus-immune mice: antigen-specific tolerance versus immunopathology. Immunity (1997) 1.39
On T cell memory: arguments for antigen dependence. Immunol Rev (1996) 1.35
Distinct migration patterns of naive and effector CD8 T cells in the spleen: correlation with CCR7 receptor expression and chemokine reactivity. Eur J Immunol (1999) 1.34
Immunotherapy of prostate cancer in the Dunning rat model: use of cytokine gene modified tumor vaccines. Cancer Res (1994) 1.33
Induction of protective cytotoxic T cell responses in the presence of high titers of virus-neutralizing antibodies: implications for passive and active immunization. J Exp Med (1998) 1.29
Beta-galactoside-binding protein secreted by activated T cells inhibits antigen-induced proliferation of T cells. Eur J Immunol (1998) 1.27
Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection. Eur J Immunol (1994) 1.23
Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection. Eur J Immunol (1998) 1.14
Break of T cell ignorance to a viral antigen in the liver induces hepatitis. J Immunol (2000) 1.13
Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model. Proc Natl Acad Sci U S A (1994) 1.12
Virus-activated CD8 T cells and lymphokine-activated NK cells express the mast cell function-associated antigen, an inhibitory C-type lectin. J Immunol (1998) 1.11
TAP1-independent loading of class I molecules by exogenous viral proteins. Eur J Immunol (1995) 1.10
T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein. Proc Natl Acad Sci U S A (1999) 1.08
Characterization of virus-specific cytotoxic T cell clones from allogeneic bone marrow chimeras. Eur J Immunol (1987) 1.06
Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny. J Exp Med (1992) 1.06
CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses. J Immunol (2000) 1.05
Concerted action of the FasL/Fas and perforin/granzyme A and B pathways is mandatory for the development of early viral hepatitis but not for recovery from viral infection. J Virol (2001) 1.05
Use of dobutamine stress echocardiography in detecting silent myocardial ischaemia in asymptomatic diabetic patients: a comparison with thallium scintigraphy and exercise testing. Diabet Med (2001) 1.05
Crucial role of TNF-alpha in CD8 T cell-mediated elimination of 3LL-A9 Lewis lung carcinoma cells in vivo. J Immunol (2000) 1.04
Qualitative and quantitative requirements for CD4+ T cell-mediated antiviral protection. J Immunol (1999) 1.02
Suppression of virus-specific antibody production by CD8+ class I-restricted antiviral cytotoxic T cells in vivo. J Virol (1992) 1.02
Strictly transporter of antigen presentation (TAP)-dependent presentation of an immunodominant cytotoxic T lymphocyte epitope in the signal sequence of a virus protein. J Exp Med (1995) 1.02
Analysis of the molecular composition of Ro ribonucleoprotein complexes. Identification of novel Y RNA-binding proteins. Eur J Biochem (2000) 1.02
Immune down-regulation and peripheral deletion of CD8 T cells does not require TNF receptor-ligand interactions nor CD95 (Fas, APO-1). Eur J Immunol (2000) 1.01
Antigen persistence and time of T-cell tolerization determine the efficacy of tolerization protocols for prevention of skin graft rejection. Nat Med (1998) 1.01
CD4+8- thymocytes bearing major histocompatibility complex class I-restricted T cell receptors: evidence for homeostatic control of early stages of CD4/CD8 lineage development. J Exp Med (1992) 1.01
Homeostatic regulation of CD8+ T cells after antigen challenge in the absence of Fas (CD95). Eur J Immunol (1996) 0.99
Bose-Einstein condensation in a surface microtrap. Phys Rev Lett (2001) 0.98
Astrocytes as antigen-presenting cells. Part II: Unlike H-2K-dependent cytotoxic T cells, H-2Ia-restricted T cells are only stimulated in the presence of interferon-gamma. J Neuroimmunol (1986) 0.97
Differences in verbal behaviours of patients with and without emotional distress during primary care consultations. Psychol Med (2000) 0.96
Restriction fine specificity of long-term, hapten-specific cytotoxic T cell clones: analysis with H-2Kbm-mutant mice and H-2Kb-specific monoclonal antibodies. Eur J Immunol (1984) 0.96
A cortisone sensitive CD3low subset of CD4+CD8- thymocytes represents an intermediate stage in intrathymic repertoire selection. Int Immunol (1992) 0.96
Dopamine D(3) receptors and salt-dependent hypertension. J Am Soc Nephrol (2001) 0.95
Elevated serum concentrations of soluble adhesion molecules in coronary artery disease and acute myocardial infarction. Eur J Med Res (1997) 0.95
CD8(+) T cells secreting type 2 lymphokines are defective in protection against viral infection. Cell Immunol (2000) 0.94
Prevention of autoimmune disease by retroviral-mediated gene therapy. J Immunol (1995) 0.93
Glyco-engineering of moss lacking plant-specific sugar residues. Plant Biol (Stuttg) (2005) 0.93
CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny. Eur J Immunol (1993) 0.93
A monoclonal antibody against altered LFA-1 induces proliferation and lymphokine release of cloned T cells. Eur J Immunol (1986) 0.92
Internet use in radiology: results of a nationwide survey. Eur J Radiol (1999) 0.92
Delayed endolymphatic hydrops and its relationship to Meniére's disease. Ann Otol Rhinol Laryngol (1990) 0.92
Superradiant rayleigh scattering and collective atomic recoil lasing in a ring cavity. Phys Rev Lett (2007) 0.91
T cell function and expression are dramatically altered in T cell receptor V gamma 1.1J gamma 4C gamma 4 transgenic mice. Cell (1989) 0.91
Enhanced positive selection of a transgenic TCR by a restriction element that does not permit negative selection. Int Immunol (1993) 0.90
Regulation of T cell production in T cell receptor transgenic mice. Eur J Immunol (1993) 0.90
Pro-inflammatory and T cell inhibitory cytokines are secreted at high levels in tumor cell cultures of human renal cell carcinoma. Eur Urol (1999) 0.89
Mitochondrial myopathies with necrotizing encephalopathy of the Leigh type. Pathol Res Pract (1988) 0.89
IL-4 differentiates naive CD8+ T cells to a "Th2-like" phenotype: a link between viral infections and bronchial asthma. Ann N Y Acad Sci (1996) 0.89
Clinician-patient communication: evidence-based recommendations to guide practice in cancer. Curr Oncol (2009) 0.88
Molecular cloning and functional expression of two members of mouse NeuAcalpha2,3Galbeta1,3GalNAc GalNAcalpha2,6-sialyltransferase family, ST6GalNAc III and IV. J Biol Chem (1999) 0.87
Analysis of immature (CD4-CD8-) thymic subsets in T-cell receptor alpha beta transgenic mice. Dev Immunol (1992) 0.87
Differentiation of CD4(high)CD8(low) coreceptor-skewed thymocytes into mature CD8 single-positive cells independent of MHC class I recognition. Eur J Immunol (1997) 0.87
The utility of the Edmonton Symptom Assessment System in screening for anxiety and depression. Eur J Cancer Care (Engl) (2012) 0.87
[Umbilical reconstruction after excision of melanomas in the area of the umbilicus]. Hautarzt (1996) 0.86
Specific deletion of the J-C delta locus in murine alpha/beta T cell clones and studies using transgenic mice. Eur J Immunol (1990) 0.86
T cell development and repertoire of mice expressing a single T cell receptor alpha chain. Eur J Immunol (1995) 0.86
T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR beta locus is incomplete but thymocyte development is not restored by TcR beta or TcR alpha beta transgenes. Eur J Immunol (1995) 0.86
Differential requirement of perforin and IFN-gamma in CD8 T cell-mediated immune responses against B16.F10 melanoma cells expressing a viral antigen. Eur J Immunol (2000) 0.86
Parental representations in drug-dependent patients and their parents. Compr Psychiatry (2000) 0.86
Intrathymic deletion of MHC class I-restricted cytotoxic T cell precursors by constitutive cross-presentation of exogenous antigen. Eur J Immunol (1999) 0.85
DNA-interactions and nuclear localisation of the chromosomal HMG domain protein SSRP1 from maize. Plant J (2000) 0.85
Protection against lymphocytic choriomeningitis virus infection induced by a reduced peptide bond analogue of the H-2Db-restricted CD8(+) T cell epitope GP33. J Biol Chem (1999) 0.85
SV40 T/t-antigen induces premature mammary gland involution by apoptosis and selects for p53 missense mutation in mammary tumors. Oncogene (1998) 0.84
Specificity of monoclonal anti-nucleosome auto-antibodies derived from lupus mice. J Autoimmun (1996) 0.84
Direct measurement of intermediate-range Casimir-Polder potentials. Phys Rev Lett (2010) 0.84
Identification of an alpha2,6-sialyltransferase induced early after lymphocyte activation. Int Immunol (1999) 0.84
Immunotherapy of bladder cancer with cytokine gene-modified tumor vaccines. Cancer Res (1994) 0.83
Plasminogen activation in focal cerebral ischemia and reperfusion. J Cereb Blood Flow Metab (2000) 0.83
[The Verona Medical Interview Classification System/Patient (VR-MICS/P): the tool and its reliability]. Epidemiol Psichiatr Soc (1999) 0.83
Primary fibroblasts from human adults as target cells for ex vivo transfection and gene therapy. Hum Gene Ther (1994) 0.83