Published in Hum Hered on November 13, 1998
An enhanced linkage map of the sheep genome comprising more than 1000 loci. Genome Res (2001) 1.97
GT repeats are associated with recombination on human chromosome 22. Genome Res (2000) 1.75
Type 2 NF1 deletions are highly unusual by virtue of the absence of nonallelic homologous recombination hotspots and an apparent preference for female mitotic recombination. Am J Hum Genet (2007) 0.94
Chromosomal speciation in mice: a cytogenetic analysis of recombination. Chromosome Res (2013) 0.83
Sex-specific incompatibility generates locus-specific rates of introgression between species. Genetics (2011) 0.79
Male and female meiotic behaviour of an intrachromosomal insertion determined by preimplantation genetic diagnosis. Mol Cytogenet (2010) 0.75
Multilocus linkage analysis in humans: detection of linkage and estimation of recombination. Am J Hum Genet (1985) 87.59
Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci U S A (1984) 48.41
Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies. Am J Hum Genet (1974) 23.66
The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA. Nucleic Acids Res (1985) 12.11
Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Res (2001) 9.41
A haplotype-based 'haplotype relative risk' approach to detecting allelic associations. Hum Hered (1992) 8.71
A computer program for linkage analysis of general human pedigrees. Am J Hum Genet (1976) 6.01
Report of the Committee on Methods of Linkage Analysis and Reporting. Cytogenet Cell Genet (1985) 5.61
Chromosome-based method for rapid computer simulation in human genetic linkage analysis. Genet Epidemiol (1993) 4.98
Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome. Nature (1989) 4.69
Counting methods (EM algorithm) in human pedigree analysis: linkage and segregation analysis. Ann Hum Genet (1977) 4.54
Relationship estimation in affected sib pair analysis of late-onset diseases. Eur J Hum Genet (1997) 4.16
Linkage analysis and family classification under heterogeneity. Ann Hum Genet (1983) 3.76
Two-trait-locus linkage analysis: a powerful strategy for mapping complex genetic traits. Am J Hum Genet (1993) 3.76
Maximum likelihood estimation by counting methods under polygenic and mixed models in human pedigrees. Am J Hum Genet (1979) 3.36
The p53MH algorithm and its application in detecting p53-responsive genes. Proc Natl Acad Sci U S A (2002) 3.11
A simple scheme for the analysis of HLA linkages in pedigrees. Ann Hum Genet (1978) 3.01
Report of the committee on linkage and gene order. Cytogenet Cell Genet (1989) 2.76
A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data. Am J Hum Genet (2001) 2.68
Linkage studies in a large kindred with familial hypercholesterolemia. Am J Hum Genet (1974) 2.49
Measuring the inflation of the lod score due to its maximization over model parameter values in human linkage analysis. Genet Epidemiol (1990) 2.47
Predisposition to familial osteoarthrosis linked to type II collagen gene. Lancet (1989) 2.43
A microsatellite genetic linkage map of human chromosome 18. Genomics (1993) 2.35
A genomewide screen for autism susceptibility loci. Am J Hum Genet (2001) 2.30
Identification of a novel common genetic risk factor for lumbar disk disease. JAMA (2001) 2.28
Alopecia universalis associated with a mutation in the human hairless gene. Science (1998) 2.23
Age-related macular degeneration. Clinical features in a large family and linkage to chromosome 1q. Arch Ophthalmol (1998) 2.19
A chi-square test to distinguish allelic association from other causes of phenotypic association between two loci. Genet Epidemiol (1985) 2.15
Risk calculations under heterogeneity. Am J Hum Genet (1989) 2.07
Selecting SNPs in two-stage analysis of disease association data: a model-free approach. Ann Hum Genet (2000) 2.05
Genetic susceptibility to heroin addiction: a candidate gene association study. Genes Brain Behav (2008) 2.00
Linkage analysis with misclassification at one locus. Clin Genet (1977) 1.89
Optic atrophy in Leber hereditary optic neuroretinopathy is probably determined by an X-chromosomal gene closely linked to DXS7. Am J Hum Genet (1991) 1.89
True pedigree errors more frequent than apparent errors for single nucleotide polymorphisms. Hum Hered (1999) 1.88
Tests of gene order from three-locus linkage data. Ann Hum Genet (1987) 1.87
An allele of COL9A2 associated with intervertebral disc disease. Science (1999) 1.85
Molecular and statistical approaches to the detection and correction of errors in genotype databases. Am J Hum Genet (1993) 1.84
Phaeohyphomycosis caused by Phaeoacremonium inflatipes. J Clin Microbiol (1998) 1.78
GT repeats are associated with recombination on human chromosome 22. Genome Res (2000) 1.75
Scan statistics to scan markers for susceptibility genes. Proc Natl Acad Sci U S A (2000) 1.73
Family cell lines available for research. Am J Hum Genet (1990) 1.72
Risk factors for postoperative bleeding after thyroid surgery. Br J Surg (2012) 1.72
Goodness-of-fit tests for locus order in three-point mapping. Genet Epidemiol (1987) 1.71
Evidence for linkage of Charcot-Marie-Tooth neuropathy to the Duffy locus on chromosome 1. Am J Hum Genet (1982) 1.69
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Epidemiology and factor analysis of obesity, type II diabetes, hypertension, and dyslipidemia (syndrome X) on the Island of Kosrae, Federated States of Micronesia. Hum Hered (2001) 1.67
Neural network analysis of complex traits. Genet Epidemiol (1997) 1.63
Assessment and management of single nucleotide polymorphism genotype errors in genetic association analysis. Pac Symp Biocomput (2001) 1.62
Refined assignment of the infantile neuronal ceroid lipofuscinosis (INCL, CLN1) locus at 1p32: incorporation of linkage disequilibrium in multipoint analysis. Genomics (1993) 1.61
TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa. Nat Genet (1998) 1.60
A microsatellite genetic linkage map of human chromosome 13. Genomics (1993) 1.57
Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden. Mol Psychiatry (2004) 1.56
A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish. Nat Genet (1996) 1.56
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Mapping of a gene for severe pediatric gastroesophageal reflux to chromosome 13q14. JAMA (2000) 1.56
Adrenoleukodystrophy: phenotypic variability and implications for therapy. J Inherit Metab Dis (1992) 1.52
A comprehensive inner-city asthma program reduces hospital and emergency room utilization. Ann Allergy Asthma Immunol (2001) 1.49
Multi-locus nonparametric linkage analysis of complex trait loci with neural networks. Hum Hered (1998) 1.49
Report of the committee on linkage and gene order. Cytogenet Cell Genet (1990) 1.48
Sequential cervical length screening in pregnancies after loop excision of the transformation zone conisation: a retrospective analysis. BJOG (2013) 1.47
p63 consensus DNA-binding site: identification, analysis and application into a p63MH algorithm. Oncogene (2007) 1.45
A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the Old Order Amish. Proc Natl Acad Sci U S A (1998) 1.45
Applications of neural networks for gene finding. Adv Genet (2001) 1.44
Filter disc supported oligonucleotide synthesis by the phosphite method. Nucleic Acids Res (1984) 1.43
Estimating distances from the centromere by means of benign ovarian teratomas in man. Ann Hum Genet (1976) 1.40
Detection of rare major genes in lipid levels. Hum Genet (1979) 1.40
Linkage probability and its approximate confidence interval under possible heterogeneity. Genet Epidemiol Suppl (1986) 1.39
Multipoint linkage analysis and heterogeneity testing in 20 X-linked retinitis pigmentosa families. Genomics (1990) 1.38
Guidelines for human linkage maps: an international system for human linkage maps (ISLM, 1990). Genomics (1991) 1.37
The role of MMAC1 mutations in early-onset breast cancer: causative in association with Cowden syndrome and excluded in BRCA1-negative cases. Am J Hum Genet (1997) 1.37
Linkage analyses of chromosome 18 markers do not identify a major susceptibility locus for bipolar affective disorder in the Old Order Amish. Am J Hum Genet (1995) 1.35
Mutation and polymorphism of the prion protein gene in Libyan Jews with Creutzfeldt-Jakob disease (CJD). Am J Hum Genet (1993) 1.34
Evidence that the penetrance of mutations at the RP11 locus causing dominant retinitis pigmentosa is influenced by a gene linked to the homologous RP11 allele. Am J Hum Genet (1997) 1.34
Heterogeneity analysis of breast cancer families by using age at onset as a covariate. Am J Hum Genet (1992) 1.33
Heroin addiction in African Americans: a hypothesis-driven association study. Genes Brain Behav (2009) 1.32
First-stage autosomal genome screen in extended pedigrees suggests genes predisposing to low bone mineral density on chromosomes 1p, 2p and 4q. Eur J Hum Genet (1998) 1.32
Significant evidence for linkage disequilibrium over a 5-cM region among Afrikaners. Genomics (2000) 1.31
Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss. J Med Genet (2008) 1.31
Genetic linkage evidence for heterogeneity in Charcot-Marie-Tooth neuropathy (HMSN type I). Ann Neurol (1983) 1.30
Family-based association studies support a sexually dimorphic effect of COMT and MAOA on genetic susceptibility to obsessive-compulsive disorder. Biol Psychiatry (1999) 1.29
Analysis of complex traits using neural networks. Genet Epidemiol (1999) 1.27
Familial rheumatoid arthritis: linkage of HLA to disease susceptibility locus in four families where proband presented with juvenile rheumatoid arthritis. J Clin Invest (1980) 1.26
Exposing the human nude phenotype. Nature (1999) 1.26
Guidelines for human linkage maps. An International System for Human Linkage Maps (ISLM, 1990). Ann Hum Genet (1991) 1.25
Genotype patterns that contribute to increased risk for or protection from developing heroin addiction. Mol Psychiatry (2008) 1.25
Pseudoxanthoma elasticum maps to an 820-kb region of the p13.1 region of chromosome 16. Genomics (1999) 1.24
Linkage evidence for genetic heterogeneity among kinships with hereditary motor and sensory neuropathy, type I. Mayo Clin Proc (1983) 1.24
Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proc Natl Acad Sci U S A (1997) 1.24
Errors and linkage disequilibrium interact multiplicatively when computing sample sizes for genetic case-control association studies. Pac Symp Biocomput (2003) 1.23
Sequence variations in the collagen IX and XI genes are associated with degenerative lumbar spinal stenosis. Ann Rheum Dis (2003) 1.23
Measurement of the electron charge asymmetry in inclusive W production in pp collisions at sqrt[s]=7 TeV. Phys Rev Lett (2012) 1.23
Detection of genetic interference: simulation studies and mouse data. Genetics (1994) 1.23
Severe autosomal dominant hypertension and brachydactyly in a unique Turkish kindred maps to human chromosome 12. Nat Genet (1996) 1.22
Linkage analysis of two-locus diseases under single-locus and two-locus analysis models. Cytogenet Cell Genet (1992) 1.21
Identification of a closely linked DNA marker, DXS178, to further refine the X-linked agammaglobulinemia locus. Genomics (1990) 1.21
Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s = 7 TeV. Phys Rev Lett (2012) 1.19
Azimuthal anisotropy of charged particles at high transverse momenta in Pb-Pb collisions at sqrt[s(NN)] = 2.76 TeV. Phys Rev Lett (2012) 1.19
Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12. Mol Psychiatry (2003) 1.19