Published in Nucleic Acids Res on October 15, 1998
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J (2001) 6.85
The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell (2003) 5.68
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO J (2000) 5.22
Sequence and structural analysis of BTB domain proteins. Genome Biol (2005) 3.88
Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nat Immunol (2010) 3.48
Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets. Mol Cell Biol (2006) 2.99
BCoR, a novel corepressor involved in BCL-6 repression. Genes Dev (2000) 2.83
Sin3: a flexible regulator of global gene expression and genome stability. Curr Genet (2004) 2.60
Transcriptional repression by blimp-1 (PRDI-BF1) involves recruitment of histone deacetylase. Mol Cell Biol (2000) 2.24
Transcriptional repression by the insulator protein CTCF involves histone deacetylases. Nucleic Acids Res (2000) 1.74
Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors. Mol Cell Biol (2002) 1.70
Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells. Blood (2009) 1.64
The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: implications for a role of BCL6 in the down-regulation of apoptosis. Proc Natl Acad Sci U S A (2002) 1.43
CtBP is an essential corepressor for BCL6 autoregulation. Mol Cell Biol (2008) 1.41
Recruitment of SMRT/N-CoR-mSin3A-HDAC-repressing complexes is not a general mechanism for BTB/POZ transcriptional repressors: the case of HIC-1 and gammaFBP-B. Proc Natl Acad Sci U S A (1999) 1.37
BCL6 controls the expression of the B7-1/CD80 costimulatory receptor in germinal center B cells. J Exp Med (2003) 1.36
Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast. Mol Cell Biol (2001) 1.32
P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL. EMBO J (2000) 1.25
mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor. Mol Cell Biol (2000) 1.24
Nuclear hormone receptor co-repressors: structure and function. Mol Cell Endocrinol (2011) 1.23
Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation. EMBO J (2008) 1.23
Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma. Histopathology (2008) 1.18
The N-terminal BTB/POZ domain and C-terminal sequences are essential for Tramtrack69 to specify cell fate in the developing Drosophila eye. Genetics (2000) 1.14
FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel subnuclear domain that includes the Tat-P-TEFb-containing nuclear speckles. Mol Biol Cell (2002) 1.14
Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasis. Mol Cell Biol (2004) 1.07
miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eμ-miR-155 transgenic mouse model. Proc Natl Acad Sci U S A (2012) 1.05
Identification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activity. Mol Cell Biol (2004) 1.04
Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator. Protein Sci (2006) 1.01
Role of LRF/Pokemon in lineage fate decisions. Blood (2013) 0.90
Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex. Biochem J (2006) 0.87
Expression of HAT1 and HDAC1, 2, 3 in Diffuse Large B-Cell Lymphomas, Peripheral T-Cell Lymphomas, and NK/T-Cell Lymphomas. Korean J Pathol (2012) 0.87
The Drosophila BCL6 homolog Ken and Barbie promotes somatic stem cell self-renewal in the testis niche. Dev Biol (2012) 0.87
The novel BTB/POZ and zinc finger factor Zbtb45 is essential for proper glial differentiation of neural and oligodendrocyte progenitor cells. Cell Cycle (2010) 0.86
BACH2-BCL6 balance regulates selection at the pre-B cell receptor checkpoint. Trends Immunol (2013) 0.85
The transcriptional corepressor SMRTER influences both Notch and ecdysone signaling during Drosophila development. Biol Open (2011) 0.84
Nuclear receptor corepressor complexes in cancer: mechanism, function and regulation. Am J Clin Exp Urol (2014) 0.82
Bcl6a function is required during optic cup formation to prevent p53-dependent apoptosis and colobomata. Hum Mol Genet (2013) 0.81
Manipulating the epigenome for the treatment of urological malignancies. Pharmacol Ther (2013) 0.81
Mutation of chromatin modifiers; an emerging hallmark of germinal center B-cell lymphomas. Blood Cancer J (2015) 0.79
The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain. PLoS One (2014) 0.78
A novel mechanism involving coordinated regulation of nuclear levels and acetylation of NF-YA and Bcl6 activates RGS4 transcription. J Biol Chem (2010) 0.78
Anti-Epileptic Drug Targets Ewing Sarcoma. J Pharm Sci Pharmacol (2014) 0.78
Mechanisms of trichostatin A inhibiting AGS proliferation and identification of lysine-acetylated proteins. World J Gastroenterol (2013) 0.78
DNA replication progresses on the periphery of nuclear aggregates formed by the BCL6 transcription factor. Mol Cell Biol (2000) 0.78
Reciprocal occupancy of BCL6 and STAT5 on Growth Hormone target genes: contrasting transcriptional outcomes and promoter-specific roles of p300 and HDAC3. Mol Cell Endocrinol (2014) 0.76
The Relationship between RUVBL1 (Pontin, TIP49, NMP238) and BCL6 in Benign and Malignant Human Lymphoid Tissues. Biochem Biophys Rep (2016) 0.75
Ikaros regulation of the BCL6/BACH2 axis and its clinical relevance in acute lymphoblastic leukemia. Oncotarget (2016) 0.75
An essential EBV latent antigen 3C binds Bcl6 for targeted degradation and cell proliferation. PLoS Pathog (2017) 0.75
The nuclear receptor superfamily: the second decade. Cell (1995) 24.99
The RXR heterodimers and orphan receptors. Cell (1995) 12.33
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell (1995) 11.72
A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature (1995) 11.18
The c-erb-A gene encodes a thyroid hormone receptor. Nature (1987) 10.53
PPAR gamma is required for placental, cardiac, and adipose tissue development. Mol Cell (1999) 10.08
Biochemical and genetic conservation of fission yeast Dsk1 and human SR protein-specific kinase 1. Mol Cell Biol (2000) 9.92
Coincidence of the promoter and capped 5' terminus of RNA from the adenovirus 2 major late transcription unit. Cell (1978) 9.60
Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RAR alpha with a novel putative transcription factor, PML. Cell (1991) 9.40
Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell (1997) 8.99
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell (1991) 8.85
Nuclear receptors and lipid physiology: opening the X-files. Science (2001) 8.76
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell (1997) 8.72
Lariat structures are in vivo intermediates in yeast pre-mRNA splicing. Cell (1984) 8.71
Identification of a receptor for the morphogen retinoic acid. Nature (1988) 8.32
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell (1998) 7.91
Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature (1986) 7.81
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A (1997) 7.52
Role of CBP/P300 in nuclear receptor signalling. Nature (1996) 7.36
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell (1992) 6.75
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature (1992) 6.69
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature (1982) 6.56
A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein. Cell (1994) 6.52
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A (1994) 6.46
Nuclear receptor that identifies a novel retinoic acid response pathway. Nature (1990) 6.23
PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med (2001) 6.09
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell (1998) 5.78
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling. Nature (1992) 5.76
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol Cell (2001) 5.76
Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature (1998) 5.63
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell (1990) 5.59
Yeast mRNA splicing in vitro. J Biol Chem (1985) 5.48
Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. Cell (1999) 5.23
Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature (1983) 5.20
LXR, a nuclear receptor that defines a distinct retinoid response pathway. Genes Dev (1995) 4.93
A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev (1998) 4.78
The initiation sites for RNA transcription in Ad2 DNA. Cell (1977) 4.76
Complex transcriptional units: diversity in gene expression by alternative RNA processing. Annu Rev Biochem (1986) 4.73
Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev (1992) 4.69
Functional domains of the human glucocorticoid receptor. Cell (1986) 4.68
Determinants of target gene specificity for steroid/thyroid hormone receptors. Cell (1989) 4.56
Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist. Nature (1989) 4.47
Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science (1987) 4.32
A transcriptional switch mediated by cofactor methylation. Science (2001) 4.32
Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature (1982) 4.30
SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes Dev (1998) 4.19
Multiple and cooperative trans-activation domains of the human glucocorticoid receptor. Cell (1988) 4.00
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes Dev (2000) 4.00
Identification of a nuclear receptor that is activated by farnesol metabolites. Cell (1995) 3.92
A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR. Cell (1991) 3.87
Identification of a new class of steroid hormone receptors. Nature (1988) 3.83
Terminal differentiation of human breast cancer through PPAR gamma. Mol Cell (1998) 3.71
Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. Nature (1993) 3.71
Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell (1995) 3.70
Production of mRNA in Chinese hamster cells: relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences. Cell (1979) 3.67
Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure. Genes Dev (1996) 3.63
Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor. Cell (1987) 3.62
Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc Natl Acad Sci U S A (1996) 3.57
RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev (1994) 3.54
Construction and identification by positive hybridization-translation of a bacterial plasmid containing a rat growth hormone structural gene sequence. Nucleic Acids Res (1978) 3.46
Retinoic acid and thyroid hormone induce gene expression through a common responsive element. Nature (1988) 3.42
Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature (2000) 3.41
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev (1999) 3.41
A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell (1999) 3.36
Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature (1995) 3.32
Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta. Nature (1998) 3.23
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor. Proc Natl Acad Sci U S A (1997) 3.22
Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene. Proc Natl Acad Sci U S A (1990) 3.17
Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. Cell (1992) 3.14
Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. Science (1987) 3.13
A repetitive DNA sequence, rhs, responsible for duplications within the Escherichia coli K-12 chromosome. J Mol Biol (1984) 3.00
Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome. Nature (2000) 2.97
Activators of the nuclear receptor PPARgamma enhance colon polyp formation. Nat Med (1998) 2.90
Retinoic acid is a negative regulator of AP-1-responsive genes. Proc Natl Acad Sci U S A (1991) 2.85
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling. Proc Natl Acad Sci U S A (1992) 2.85
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci U S A (2001) 2.83
Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein. Proc Natl Acad Sci U S A (1997) 2.82
Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors. Genes Dev (1994) 2.78
Identification of human glucocorticoid receptor complementary DNA clones by epitope selection. Science (1985) 2.77
Determinants for selective RAR and TR recognition of direct repeat HREs. Genes Dev (1993) 2.76
Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. Science (1984) 2.75
Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro. Cell (1985) 2.75
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Genes Dev (2001) 2.68
Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene. Cell (1990) 2.68
Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. J Clin Invest (2000) 2.67
The purified yeast pre-mRNA splicing factor PRP2 is an RNA-dependent NTPase. EMBO J (1992) 2.60
The histone acetylase PCAF is a nuclear receptor coactivator. Genes Dev (1998) 2.58
Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/CGRP gene expression. Cell (1987) 2.58
Differential activation of adipogenesis by multiple PPAR isoforms. Genes Dev (1996) 2.58
Mechanism of corepressor binding and release from nuclear hormone receptors. Genes Dev (1999) 2.57
LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas. Nat Genet (1993) 2.49
The yeast RNA gene products are essential for mRNA splicing in vitro. Cell (1986) 2.49