Published in J Immunol on October 15, 1998
Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol (2003) 2.93
Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity (2007) 2.88
T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription. J Exp Med (2006) 2.70
GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells. J Exp Med (2000) 2.68
Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation. J Exp Med (1998) 2.40
Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation. J Clin Invest (1999) 2.03
The enhancer HS2 critically regulates GATA-3-mediated Il4 transcription in T(H)2 cells. Nat Immunol (2010) 1.72
T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. Nat Commun (2012) 1.39
Gene expression profile of murine long-term reconstituting vs. short-term reconstituting hematopoietic stem cells. Proc Natl Acad Sci U S A (2005) 1.32
Th2 cell-specific cytokine expression and allergen-induced airway inflammation depend on JunB. EMBO J (2002) 1.31
Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells. J Exp Med (2001) 1.26
Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis. Mol Cell Biol (2002) 1.21
Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs. EMBO J (2000) 1.17
Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA. J Mol Biol (2008) 1.14
Bcl6 controls the Th2 inflammatory activity of regulatory T cells by repressing Gata3 function. J Immunol (2012) 1.13
Regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function. Proc Natl Acad Sci U S A (2006) 1.07
Gfi1-mediated stabilization of GATA3 protein is required for Th2 cell differentiation. J Biol Chem (2008) 1.04
JunD regulates lymphocyte proliferation and T helper cell cytokine expression. EMBO J (2004) 1.04
Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease. PLoS Med (2009) 1.03
Natural killer type 2 bias in remission of multiple sclerosis. J Clin Invest (2001) 1.02
Interleukin-5 and IL-5 receptor in health and diseases. Proc Jpn Acad Ser B Phys Biol Sci (2011) 1.00
Immunopathological roles of cytokines, chemokines, signaling molecules, and pattern-recognition receptors in systemic lupus erythematosus. Clin Dev Immunol (2012) 0.98
Transcriptional and epigenetic regulation of T-helper lineage specification. Immunol Rev (2014) 0.97
Th1 and Th2 cytokine production is suppressed at the level of transcriptional regulation in Kawasaki disease. Clin Exp Immunol (2004) 0.95
'All things considered': transcriptional regulation of T helper type 2 cell differentiation from precursor to effector activation. Immunology (2013) 0.94
Epigenetic control of cytokine gene expression: regulation of the TNF/LT locus and T helper cell differentiation. Adv Immunol (2013) 0.94
Kinetics of GATA-3 gene expression in early polarizing and committed human T cells. Immunology (2001) 0.90
Overexpression of the transcription factor GATA-3 enhances the development of pulmonary fibrosis. Am J Pathol (2006) 0.90
Cytotoxic T-lymphocyte antigen-4 inhibits GATA-3 but not T-bet mRNA expression during T helper cell differentiation. Immunology (2006) 0.89
Differential expression of mRNA for Th1 and Th2 cytokine-associated transcription factors and suppressors of cytokine signalling in peripheral blood mononuclear cells of patients with atopic dermatitis. Clin Exp Immunol (2004) 0.89
Compound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cells. PLoS One (2012) 0.88
Interleukin-6 promotes the production of interleukin-4 and interleukin-5 by interleukin-2-dependent and -independent mechanisms in freshly isolated human T cells. Immunology (2002) 0.88
Cyclic AMP-induced chromatin changes support the NFATc-mediated recruitment of GATA-3 to the interleukin 5 promoter. J Biol Chem (2008) 0.86
The differential expression of IL-4 and IL-13 and its impact on type-2 immunity. Cytokine (2015) 0.84
Impairment of host defense against disseminated candidiasis in mice overexpressing GATA-3. Infect Immun (2010) 0.84
Review article: molecular signals and genetic reprogramming in peripheral T-cell differentiation. Immunology (2000) 0.84
Interleukin-21 suppresses the differentiation and functions of T helper 2 cells. Immunology (2015) 0.83
Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation. Mucosal Immunol (2015) 0.80
IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release. PLoS One (2016) 0.79
Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer. Breast Cancer Res (2014) 0.79
DNase I footprinting of the human interleukin-5 gene promoter. Immunology (2000) 0.79
Transcriptional regulation of T helper type 2 differentiation. Immunology (2014) 0.76
Development of chronic allergic responses by dampening Bcl6-mediated suppressor activity in memory T helper 2 cells. Proc Natl Acad Sci U S A (2017) 0.75
Differential Expression of T-bet and GATA3 in Egyptian Children with Idiopathic Thrombocytopenic Purpura. Indian J Hematol Blood Transfus (2015) 0.75
NFκB attenuates IL-5 production and upregulates T-box transcription factors in Th2-like T cells. Cytotechnology (2013) 0.75
Dermatophagoides pteronyssinus immunotherapy changes the T-regulatory cell activity. Sci Rep (2017) 0.75
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature (2000) 64.32
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell (2000) 10.90
Binding of large organic anions and neutral molecules by native bovine serum albumin. Biochemistry (1966) 5.01
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med (2001) 4.83
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice. Proc Natl Acad Sci U S A (2001) 4.62
Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II. Science (1984) 4.52
Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II. J Biol Chem (1984) 3.98
Membrane pores induced by magainin. Biochemistry (1996) 3.97
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest (2001) 3.86
A critical role for NF-kappa B in GATA3 expression and TH2 differentiation in allergic airway inflammation. Nat Immunol (2001) 3.74
Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene. J Biol Chem (1997) 3.66
Cloning and characterization of adeno-associated virus type 5. J Virol (1999) 3.36
CYP3A variation and the evolution of salt-sensitivity variants. Am J Hum Genet (2004) 3.32
Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro. Proc Natl Acad Sci U S A (1987) 3.21
Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo. Nature (1998) 3.16
Cleavage of DNA by mammalian DNA topoisomerase II. J Biol Chem (1983) 3.05
Human magnetic resonance imaging at 8 T. NMR Biomed (1998) 2.96
Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles. J Virol (1997) 2.91
Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product. Proc Natl Acad Sci U S A (1991) 2.86
Sphingosine 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum. J Biochem (1997) 2.51
Essential role of nuclear factor kappaB in the induction of eosinophilia in allergic airway inflammation. J Exp Med (1998) 2.40
The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. Cold Spring Harb Symp Quant Biol (1999) 2.40
AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL. Br J Cancer (2006) 2.33
Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. Proc Natl Acad Sci U S A (2000) 2.30
Fatigue testing median sternotomy closures. Eur J Cardiothorac Surg (2001) 2.27
An international two-stage genome-wide search for schizophrenia susceptibility genes. Nat Genet (1995) 2.26
The hedgehog pathway regulates remodelling responses to biliary obstruction in rats. Gut (2008) 2.26
Experimental evidence for hydrophobic matching and membrane-mediated interactions in lipid bilayers containing gramicidin. Biophys J (1999) 2.23
Pollen tube guidance by the female gametophyte. Development (1997) 2.22
Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression. Nat Med (2000) 2.04
The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. Proc Natl Acad Sci U S A (1994) 2.04
Airway protection during experimental CPR. Chest (1995) 1.96
p53 immunostaining as a marker of malignant disease in diagnostic cytopathology. Lancet (1991) 1.95
Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3. J Biol Chem (1999) 1.91
Quantum confinement and electronic properties of silicon nanowires. Phys Rev Lett (2004) 1.91
Tissue-specific expression of murine Nkx3.1 in the male urogenital system. Dev Dyn (1997) 1.90
Maternal effects of the short integument mutation on embryo development in Arabidopsis. Dev Biol (1996) 1.89
Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells. J Thromb Haemost (2008) 1.88
Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3. Immunity (1999) 1.88
Comparison of microvascular permeability measurements, K(trans), determined with conventional steady-state T1-weighted and first-pass T2*-weighted MR imaging methods in gliomas and meningiomas. AJNR Am J Neuroradiol (2006) 1.87
Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation. Hum Mol Genet (2000) 1.85
Formation of functional tissue from transplanted adrenocortical cells expressing telomerase reverse transcriptase. Nat Biotechnol (2000) 1.84
Computational drug repositioning: from data to therapeutics. Clin Pharmacol Ther (2013) 1.82
Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs. Proc Natl Acad Sci U S A (1998) 1.81
Structure of the red fluorescence band in chloroplasts. J Gen Physiol (1966) 1.77
Theoretical analysis of hydrophobic matching and membrane-mediated interactions in lipid bilayers containing gramicidin. Biophys J (1999) 1.77
Assessing pollution prevention program by QUAL2E simulation analysis for the Kao-Ping River Basin, Taiwan. J Environ Manage (2001) 1.77
Genes that are uniquely stress regulated in salt overly sensitive (sos) mutants. Plant Physiol (2001) 1.69
Epinephrine increases the severity of postresuscitation myocardial dysfunction. Circulation (1995) 1.68
Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A (1998) 1.68
Interferometer-controlled scanning transmission X-ray microscopes at the Advanced Light Source. J Synchrotron Radiat (2003) 1.68
Geometry and surface characteristics of gold nanoparticles influence their biodistribution and uptake by macrophages. Eur J Pharm Biopharm (2010) 1.67
sin 1, a mutation affecting female fertility in Arabidopsis, interacts with mod 1, its recessive modifier. Genetics (1994) 1.66
Outer surface lipoproteins of Borrelia burgdorferi stimulate nitric oxide production by the cytokine-inducible pathway. Infect Immun (1994) 1.66
Rhinovirus stimulation of interleukin-6 in vivo and in vitro. Evidence for nuclear factor kappa B-dependent transcriptional activation. J Clin Invest (1996) 1.66
A relativistic type Ibc supernova without a detected gamma-ray burst. Nature (2010) 1.64
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease. J Neurosci (2001) 1.64
Membrane thinning effect of the beta-sheet antimicrobial protegrin. Biochemistry (2000) 1.64
Repression of interleukin-6 gene expression by 17 beta-estradiol: inhibition of the DNA-binding activity of the transcription factors NF-IL6 and NF-kappa B by the estrogen receptor. FEBS Lett (1997) 1.58
Short duration of sleep and unintentional injuries among adolescents in China. Am J Epidemiol (2007) 1.58
Beta 2-microglobulin-independent MHC class Ib molecule expressed by human intestinal epithelium. Science (1994) 1.57
In vivo mapping of DNA topoisomerase II-specific cleavage sites on SV40 chromatin. Cell (1985) 1.57
Matrix metalloproteinase-9 may be a potential therapeutic target in epilepsy. Med Hypotheses (2011) 1.54
Identification of DNA topoisomerase II as an intracellular target of antitumor epipodophyllotoxins in simian virus 40-infected monkey cells. Cancer Res (1985) 1.53
Design and assembly of an 8 tesla whole-body MR scanner. J Comput Assist Tomogr (1999) 1.52
Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease. J Neurosci (1998) 1.52
Beat-to-beat repolarization variability in ventricular myocytes and its suppression by electrical coupling. Am J Physiol Heart Circ Physiol (2000) 1.51
Transcriptional induction of multiple cytokines by human respiratory syncytial virus requires activation of NF-kappa B and is inhibited by sodium salicylate and aspirin. Virology (1997) 1.46
Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-kappaB activation. Biochem Pharmacol (2000) 1.46
Astrocyte elevated gene-1 is a proliferation promoter in breast cancer via suppressing transcriptional factor FOXO1. Oncogene (2009) 1.46
Molecular Characterization of the Brittle-2 Gene Effect on Maize Endosperm ADPglucose Pyrophosphorylase Subunits. Plant Physiol (1990) 1.45
Osteopontin levels are elevated in patients with asthma. J Int Med Res (2011) 1.45
Drilling efficiency and temperature elevation of three types of Kirschner-wire point. J Bone Joint Surg Br (2002) 1.44
Hepatitis G virus infection before and after liver transplantation. Liver Transplantation Database. Liver Transpl Surg (1997) 1.44
Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine. Nat Med (2000) 1.41
Isolation of an active transcription initiation complex from HeLa cell-free extract. Proc Natl Acad Sci U S A (1984) 1.40
Variable oxygenation response to inhaled nitric oxide in severe persistent pulmonary hypertension of the newborn. Acta Paediatr (1995) 1.40
Adaptors, linkers, and methylation. Methods Enzymol (1987) 1.39
Ultrahigh-Resolution X-ray Tomography. Science (1994) 1.39
Temperature measurement after severe head injury. Anaesthesia (2004) 1.38
Increased sputum amino acid concentrations and auxotrophy of Pseudomonas aeruginosa in severe cystic fibrosis lung disease. Thorax (2000) 1.37
EP2, a receptor for PGE2, regulates tumor angiogenesis through direct effects on endothelial cell motility and survival. Oncogene (2006) 1.37
Creatine and cyclocreatine attenuate MPTP neurotoxicity. Exp Neurol (1999) 1.37
Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry. Science (1998) 1.36
Effects of adiponectin on breast cancer cell growth and signaling. Br J Cancer (2008) 1.35
Oncogenic TLS/ERG and EWS/Fli-1 fusion proteins inhibit RNA splicing mediated by YB-1 protein. Cancer Res (2001) 1.34
Molecular analysis of the mitochondrial 12S rRNA and tRNASer(UCN) genes in paediatric subjects with non-syndromic hearing loss. J Med Genet (2004) 1.34
Search for neutrinoless double-beta decay in 136Xe with EXO-200. Phys Rev Lett (2012) 1.33
Localization of the pannexin1 protein at postsynaptic sites in the cerebral cortex and hippocampus. Neuroscience (2007) 1.33
Expression and function of interleukin-6 in epithelial cells. J Cell Biochem (1991) 1.32
Risk factors for surgical site infections after breast surgery: a systematic review and meta-analysis. Eur J Surg Oncol (2012) 1.31
Determination of adeno-associated virus Rep68 and Rep78 binding sites by random sequence oligonucleotide selection. J Virol (1995) 1.31
STAT1-regulated lung MDSC-like cells produce IL-10 and efferocytose apoptotic neutrophils with relevance in resolution of bacterial pneumonia. Mucosal Immunol (2012) 1.29
Roles of Epstein-Barr virus glycoproteins gp350 and gp25 in the infection of human epithelial cells. J Gen Virol (2001) 1.27
The in vivo mutagenic frequency and specificity of O6-methylguanine in phi X174 replicative form DNA. Proc Natl Acad Sci U S A (1986) 1.27
TLR4/MyD88-induced CD11b+Gr-1 int F4/80+ non-migratory myeloid cells suppress Th2 effector function in the lung. Mucosal Immunol (2010) 1.27