Published in Mol Cell Biol on December 01, 1998
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness. Genes Dev (2000) 4.23
A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development. Genes Dev (1999) 3.91
All Tcf HMG box transcription factors interact with Groucho-related co-repressors. Nucleic Acids Res (2001) 2.98
Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins. EMBO Rep (2002) 2.21
Repression by Groucho/TLE/Grg proteins: genomic site recruitment generates compacted chromatin in vitro and impairs activator binding in vivo. Mol Cell (2007) 2.12
Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family. EMBO J (2000) 1.79
Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast. EMBO J (2000) 1.62
Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance. Plant Cell (2006) 1.58
Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split. Mol Cell Biol (2002) 1.52
Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev (2001) 1.50
The Groucho/TLE/Grg family of transcriptional co-repressors. Genome Biol (2008) 1.46
Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex. Mol Cell Biol (2001) 1.37
Groucho oligomerization is required for repression in vivo. Mol Cell Biol (2004) 1.36
Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression. BMC Cancer (2009) 1.26
Role for Hes1-induced phosphorylation in Groucho-mediated transcriptional repression. Mol Cell Biol (2002) 1.24
Oligomerization of ETO is obligatory for corepressor interaction. Mol Cell Biol (2001) 1.22
Analysis of Groucho-histone interactions suggests mechanistic similarities between Groucho- and Tup1-mediated repression. Nucleic Acids Res (2000) 1.20
The Groucho ortholog UNC-37 interacts with the short Groucho-like protein LSY-22 to control developmental decisions in C. elegans. Development (2010) 1.18
Transcriptional autoregulation and inhibition of mRNA translation of amino acid regulator gene cpcA of filamentous fungus Aspergillus nidulans. Mol Biol Cell (2001) 1.08
Stable chromosomal association of MSL2 defines a dosage-compensated nuclear compartment. Chromosoma (2005) 1.06
Differential in vivo requirements for oligomerization during Groucho-mediated repression. EMBO Rep (2007) 1.05
Molecular functions of the TLE tetramerization domain in Wnt target gene repression. EMBO J (2014) 1.02
Transcriptional repression: conserved and evolved features. Curr Biol (2010) 1.02
Histone deacetylase-related protein inhibits AES-mediated neuronal cell death by direct interaction. J Neurosci Res (2008) 1.00
Groucho-mediated repression may result from a histone deacetylase-dependent increase in nucleosome density. PLoS One (2010) 0.99
Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response. Mol Cell Biol (2002) 0.98
Phosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1. PLoS One (2010) 0.97
A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes. Immunology (2002) 0.97
Functional dissection of the global repressor Tup1 in yeast: dominant role of the C-terminal repression domain. Genetics (2002) 0.94
The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors. Biochem J (2009) 0.92
Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors. Mol Cell Biol (2006) 0.91
AES/GRG5: more than just a dominant-negative TLE/GRG family member. Dev Dyn (2010) 0.90
Regulation of SMRT corepressor dimerization and composition by MAP kinase phosphorylation. Mol Cell Endocrinol (2010) 0.87
Crystal structure of the N-terminal domain of the yeast general corepressor Tup1p and its functional implications. J Biol Chem (2012) 0.87
The Dorsal Rel homology domain plays an active role in transcriptional regulation. Mol Cell Biol (2002) 0.86
The Groucho co-repressor is primarily recruited to local target sites in active chromatin to attenuate transcription. PLoS Genet (2014) 0.86
Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway. Proc Natl Acad Sci U S A (2016) 0.85
Dorsal interacting protein 3 potentiates activation by Drosophila Rel homology domain proteins. Dev Comp Immunol (2008) 0.85
The corepressor Tle4 is a novel regulator of murine hematopoiesis and bone development. PLoS One (2014) 0.83
Differential modulation of TCF/LEF-1 activity by the soluble LRP6-ICD. PLoS One (2010) 0.83
Cell Fate and Differentiation of Bone Marrow Mesenchymal Stem Cells. Stem Cells Int (2016) 0.79
The unconserved groucho central region is essential for viability and modulates target gene specificity. PLoS One (2012) 0.79
An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP. Elife (2015) 0.78
The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub. J Biol Chem (2015) 0.77
Mechanisms of Groucho-mediated repression revealed by genome-wide analysis of Groucho binding and activity. BMC Genomics (2017) 0.75
GRG5/AES interacts with T-cell factor 4 (TCF4) and downregulates Wnt signaling in human cells and zebrafish embryos. PLoS One (2013) 0.75
The transcriptional co-repressor TLE3 regulates myogenic differentiation by repressing the activity of the MyoD transcription factor. J Biol Chem (2017) 0.75
Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases. Biochim Biophys Acta (1966) 16.27
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif. Cell (1988) 12.68
The ancient regulatory-protein family of WD-repeat proteins. Nature (1994) 9.33
Ssn6-Tup1 is a general repressor of transcription in yeast. Cell (1992) 8.54
The 2.0 A crystal structure of a heterotrimeric G protein. Nature (1996) 6.77
What's up and down with histone deacetylation and transcription? Cell (1997) 5.99
MultiCoil: a program for predicting two- and three-stranded coiled coils. Protein Sci (1997) 5.92
Crystal structure of a G-protein beta gamma dimer at 2.1A resolution. Nature (1996) 5.87
CENP-E is a putative kinetochore motor that accumulates just before mitosis. Nature (1992) 5.54
3D domain swapping: a mechanism for oligomer assembly. Protein Sci (1995) 4.96
Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell (1994) 4.95
Synergistic activation by the glutamine-rich domains of human transcription factor Sp1. Cell (1989) 4.49
Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein. Proc Natl Acad Sci U S A (1983) 4.38
Eukaryotic transcription: an interlaced network of transcription factors and chromatin-modifying machines. Cell (1998) 3.92
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms. Science (1995) 3.69
The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain. Mol Cell Biol (1996) 3.06
Characterization of TUP1, a mediator of glucose repression in Saccharomyces cerevisiae. Mol Cell Biol (1990) 3.02
High-resolution structure of the oligomerization domain of p53 by multidimensional NMR. Science (1994) 2.98
Yeast heterochromatin: regulation of its assembly and inheritance by histones. Cell (1998) 2.85
Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins. Nat Genet (1992) 2.71
Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed. Genes Dev (1997) 2.38
Structure and expression of the murine N-myc gene. Proc Natl Acad Sci U S A (1986) 2.36
Groucho-dependent and -independent repression activities of Runt domain proteins. Mol Cell Biol (1997) 2.27
The Groucho/transducin-like enhancer of split transcriptional repressors interact with the genetically defined amino-terminal silencing domain of histone H3. J Biol Chem (1997) 2.26
The Drosophila hairy protein acts in both segmentation and bristle patterning and shows homology to N-myc. EMBO J (1989) 2.18
The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs. Mol Cell Biol (1990) 2.13
The p53 protein is an unusually shaped tetramer that binds directly to DNA. Proc Natl Acad Sci U S A (1993) 2.11
A deduced gene product from the Drosophila neurogenic locus, enhancer of split, shows homology to mammalian G-protein beta subunit. Cell (1988) 2.01
Conversion of dorsal from an activator to a repressor by the global corepressor Groucho. Genes Dev (1997) 1.99
The Cyc8 (Ssn6)-Tup1 corepressor complex is composed of one Cyc8 and four Tup1 subunits. Mol Cell Biol (1996) 1.94
Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins. Genetics (1992) 1.87
The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell (1994) 1.85
The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins. Proc Natl Acad Sci U S A (1992) 1.76
Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer. Mol Cell Biol (1998) 1.71
Groucho: making its Marx as a transcriptional co-repressor. Trends Genet (1998) 1.58
deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination. Cell (1992) 1.55
Molecular weights of protein multimers from polyacrylamide gel electrophoresis. Anal Biochem (1977) 1.54
The molecular genetics of Enhancer of split, a gene required for embryonic neural development in Drosophila. EMBO J (1988) 1.48
Residues in the WD repeats of Tup1 required for interaction with alpha2. Mol Cell Biol (1997) 1.36
Drosophila CBP is required for dorsal-dependent twist gene expression. Nat Genet (1997) 1.29
Products of the grg (Groucho-related gene) family can dimerize through the amino-terminal Q domain. J Biol Chem (1996) 1.27
Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development. Mech Dev (1996) 1.21
Affinity for the nuclear compartment and expression during cell differentiation implicate phosphorylated Groucho/TLE1 forms of higher molecular mass in nuclear functions. Biochem J (1996) 1.17
Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures. Dev Dyn (1997) 1.15
Cloning and developmental expression of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex. Mech Dev (1993) 1.13
A direct contact between the dorsal rel homology domain and Twist may mediate transcriptional synergy. Mol Cell Biol (1997) 1.11
The establishment and interpretation of transcription factor gradients in the Drosophila embryo. Biochim Biophys Acta (1995) 1.08
Mechanisms of early neurogenesis in Drosophila melanogaster. J Neurobiol (1993) 1.07
Protein folding and intracellular transport: evaluation of conformational changes in nascent exocytotic proteins. Methods Cell Biol (1989) 1.06
Cloning of the murine homolog of the leukemia-associated PML gene. Mamm Genome (1995) 0.97
The role of the enhancer of split complex during cell fate determination in Drosophila. Dev Suppl (1993) 0.96
Reconstitution of TATA-binding protein-associated factor/TATA-binding protein complexes for in vitro transcription. Methods Enzymol (1996) 0.88
A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development. Genes Dev (1999) 3.91
Groucho/TLE family proteins and transcriptional repression. Gene (2000) 3.31
Distinct regions of Sp1 modulate DNA binding and transcriptional activation. Science (1988) 3.23
Cruciform formation in a negatively supercoiled DNA may be kinetically forbidden under physiological conditions. Cell (1983) 2.69
DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement. Proc Natl Acad Sci U S A (1991) 2.51
The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression. Genes Dev (1993) 2.14
Conversion of dorsal from an activator to a repressor by the global corepressor Groucho. Genes Dev (1997) 1.99
Dorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer. Mol Cell Biol (1998) 1.71
Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region. Genes Dev (1991) 1.66
The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression. Genes Dev (1995) 1.58
Influence of muscle fiber type and pedal frequency on oxygen uptake kinetics of heavy exercise. J Appl Physiol (1985) (1996) 1.45
The use of psoralen-modified DNA to probe the mechanism of enhancer action. Cell (1986) 1.32
Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic. Genes Dev (1995) 1.31
A functional interaction between dorsal and components of the Smt3 conjugation machinery. J Biol Chem (2000) 1.24
Analysis of Groucho-histone interactions suggests mechanistic similarities between Groucho- and Tup1-mediated repression. Nucleic Acids Res (2000) 1.20
The same dorsal binding site mediates both activation and repression in a context-dependent manner. EMBO J (1992) 1.19
A direct contact between the dorsal rel homology domain and Twist may mediate transcriptional synergy. Mol Cell Biol (1997) 1.11
Activation and repression by the C-terminal domain of Dorsal. Development (2001) 1.00
Complex regulatory region mediating tailless expression in early embryonic patterning and brain development. Development (1997) 0.98
Modulation of Igf2 genomic imprinting in mice induced by 5-azacytidine, an inhibitor of DNA methylation. Mol Endocrinol (1997) 0.91
The bipartite D. melanogaster twist promoter is reorganized in D. virilis. Mech Dev (1994) 0.90
Cooperativity in transcriptional control. Curr Biol (2001) 0.89
The decapentaplegic core promoter region plays an integral role in the spatial control of transcription. Mol Cell Biol (1995) 0.84
Baculovirus-transfer vector for eukaryotic expression and immunoaffinity purification of Gal4-fusion proteins. Biotechniques (1999) 0.83
Influence of muscle fibre type and fitness on the oxygen uptake/power output slope during incremental exercise in humans. Exp Physiol (2000) 0.83
Expression of the apoptosis-related genes, caspase-1, caspase-3, DNA fragmentation factor, and apoptotic protease activating factor-1, in human granulosa cells. Fertil Steril (1998) 0.79
Elevation of internal auditory canal pressure by vestibular schwannomas. Otol Neurotol (2001) 0.79
Nitric oxide production during exercise in chronic heart failure. Am Heart J (1997) 0.79
Regulation of dorso/ventral patterning in the Drosophila embryo by multiple dorsal-interacting proteins. Cell Biochem Biophys (2000) 0.78
Characterization of downstream elements in a Raf-1 pathway. Proc Natl Acad Sci U S A (1993) 0.78
Effects of cocaine and corticotropin-releasing factor on pulsatile ACTH and cortisol release in ovariectomized rhesus monkeys. J Clin Endocrinol Metab (1995) 0.76
Protective effect of a 21-aminosteroid against hemorrhage-induced ischemia-reperfusion injury in the rat stomach: role of lipid peroxidation. Shock (1995) 0.75
Second-site antibiotic resistance mutations in the ribosomal region of yeast mitochondrial DNA. Curr Genet (1982) 0.75
Adsorption of water vapor by poly(styrenesulfonic acid), sodium salt: isothermal and isobaric adsorption equilibria. J Colloid Interface Sci (2004) 0.75
A User Study on Curved Edges in Graph Visualization. IEEE Trans Vis Comput Graph (2012) 0.75
Challenges of assuring crew safety in space shuttle missions with international cargoes. Acta Astronaut (2004) 0.75
CADIAG-2 and MYCIN-like systems. Artif Intell Med (1997) 0.75