Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae.

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Published in Microbiol Mol Biol Rev on December 01, 1998

Authors

S M Faruque1, M J Albert, J J Mekalanos

Author Affiliations

1: Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka-1000, Bangladesh. faruque@icddrb.org

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Outbreak of Vibrio cholerae non-O1 in India and Bangladesh. Lancet (1993) 4.11

Why treatment centres failed to prevent cholera deaths among Rwandan refugees in Goma, Zaire. Lancet (1995) 4.06

Studies on toxinogenesis in Vibrio cholerae. I. Isolation of mutants with altered toxinogenicity. J Infect Dis (1974) 4.02

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Endemic cholera in rural East Pakistan. Am J Epidemiol (1969) 2.06

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Emergence of multiply antibiotic-resistant Vibrio cholerae in Bangladesh. J Infect Dis (1980) 1.97

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Identification of a mannose-binding pilus on Vibrio cholerae El Tor. Microb Pathog (1991) 1.94

Additional serovars and inter-O antigenic relationships of Vibrio cholerae. Jpn J Med Sci Biol (1977) 1.93

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Cholera epidemics in Bangladesh: 1985-1991. J Diarrhoeal Dis Res (1992) 1.92

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A prototype live oral cholera vaccine. Nature (1971) 1.65

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Epidemiologic analysis of endemic cholera in urban East Pakistan, 1964-1966. Am J Epidemiol (1969) 1.29

Emerging infections: getting ahead of the curve. Emerg Infect Dis (1996) 1.29

The aquatic environment as a reservoir of Vibrio cholerae: a review. J Diarrhoeal Dis Res (1993) 1.28

The human pathogenic vibrios--a public health update with environmental perspectives. Epidemiol Infect (1989) 1.26

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Identification of a vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage. Proc Natl Acad Sci U S A (1999) 3.75

Use of recombinase gene fusions to identify Vibrio cholerae genes induced during infection. Mol Microbiol (1995) 3.69

Molecular cloning of Vibrio cholerae enterotoxin genes in Escherichia coli K-12. Proc Natl Acad Sci U S A (1982) 3.68

Alkaline phosphatase fusions: sensors of subcellular location. J Bacteriol (1990) 3.59

Hyperactive transposase mutants of the Himar1 mariner transposon. Proc Natl Acad Sci U S A (1999) 3.45

CTX genetic element encodes a site-specific recombination system and an intestinal colonization factor. Proc Natl Acad Sci U S A (1993) 3.34

Nucleotide sequence of the type A staphylococcal enterotoxin gene. J Bacteriol (1988) 3.26

Nucleotide sequence of the Shiga-like toxin genes of Escherichia coli. Proc Natl Acad Sci U S A (1987) 3.25

Use of signature-tagged transposon mutagenesis to identify Vibrio cholerae genes critical for colonization. Mol Microbiol (1998) 3.24

Regulation, replication, and integration functions of the Vibrio cholerae CTXphi are encoded by region RS2. Mol Microbiol (1997) 3.22

Genetic characterization of a new type IV-A pilus gene cluster found in both classical and El Tor biotypes of Vibrio cholerae. Infect Immun (1999) 3.10

Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation. Cell (1991) 3.09

ToxR regulates virulence gene expression in non-O1 strains of Vibrio cholerae that cause epidemic cholera. Infect Immun (1994) 3.08

Genetic regulation of bacterial virulence. Annu Rev Genet (1989) 2.98

Enzymic activity of cholera toxin. II. Relationships to proteolytic processing, disulfide bond reduction, and subunit composition. J Biol Chem (1979) 2.93

Isolation of enterotoxin structural gene deletion mutations in Vibrio cholerae induced by two mutagenic vibriophages. Proc Natl Acad Sci U S A (1982) 2.92

Affinity filters, a new approach to the isolation of tox mutants of Vibrio cholerae. Proc Natl Acad Sci U S A (1978) 2.89

Identification of toxS, a regulatory gene whose product enhances toxR-mediated activation of the cholera toxin promoter. J Bacteriol (1989) 2.87

Transcription of Ti plasmid-derived sequences in three octopine-type crown gall tumor lines. Proc Natl Acad Sci U S A (1979) 2.83

Distinct roles of an alternative sigma factor during both free-swimming and colonizing phases of the Vibrio cholerae pathogenic cycle. Mol Microbiol (1998) 2.74

Vibrio cholerae O139 synonym bengal is closely related to Vibrio cholerae El Tor but has important differences. Infect Immun (1994) 2.73

Prevalence of toxin types and colonization factors in enterotoxigenic Escherichia coli isolated during a 2-year period from diarrheal patients in Bangladesh. J Clin Microbiol (2000) 2.69

The Vibrio cholerae O139 serogroup antigen includes an O-antigen capsule and lipopolysaccharide virulence determinants. Proc Natl Acad Sci U S A (1994) 2.68

Emergence of a new cholera pandemic: molecular analysis of virulence determinants in Vibrio cholerae O139 and development of a live vaccine prototype. J Infect Dis (1994) 2.67

Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium. Infect Immun (1992) 2.66

Genetic analysis of the cholera toxin-positive regulatory gene toxR. J Bacteriol (1985) 2.59

Staphylococcal enterotoxin A is encoded by phage. Science (1985) 2.57

Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host. Proc Natl Acad Sci U S A (1995) 2.57

Expression of ToxR, the transcriptional activator of the virulence factors in Vibrio cholerae, is modulated by the heat shock response. Proc Natl Acad Sci U S A (1990) 2.56

Simple method for purifying choleragenoid, the natural toxoid of Vibrio cholerae. Infect Immun (1977) 2.56

Confirmation of the Fur operator site by insertion of a synthetic oligonucleotide into an operon fusion plasmid. J Bacteriol (1988) 2.49

Safety, immunogenicity, and efficacy of live attenuated Vibrio cholerae O139 vaccine prototype. Lancet (1995) 2.43

Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I. Proc Natl Acad Sci U S A (1988) 2.38

Morphological studies on fimbriae expressed by Vibrio cholerae 01. Microb Pathog (1988) 2.33

In vivo covalent cross-linking of cellular actin by the Vibrio cholerae RTX toxin. EMBO J (2000) 2.32

Evidence of high-frequency genomic reassortment of group A rotavirus strains in Bangladesh: emergence of type G9 in 1995. J Clin Microbiol (1999) 2.31

Characterization of defensin resistance phenotypes associated with mutations in the phoP virulence regulon of Salmonella typhimurium. Infect Immun (1990) 2.25

In vivo genetic analysis of bacterial virulence. Annu Rev Microbiol (1999) 2.23

Isolation of enterotoxigenic Bacteroides fragilis from Bangladeshi children with diarrhea: a controlled study. J Clin Microbiol (1994) 2.23

Regulation of cholera toxin by temperature, pH, and osmolarity. Methods Enzymol (1994) 2.23

Effect of a recA mutation on cholera toxin gene amplification and deletion events. J Bacteriol (1986) 2.22

Use of genetic recombination as a reporter of gene expression. Proc Natl Acad Sci U S A (1994) 2.21

Vibrio parahaemolyticus has a homolog of the Vibrio cholerae toxRS operon that mediates environmentally induced regulation of the thermostable direct hemolysin gene. J Bacteriol (1993) 2.18

Vibrio cholerae tolC is required for bile resistance and colonization. Infect Immun (2001) 2.17

Purification of cholera toxin and its subunits: new methods of preparation and the use of hypertoxinogenic mutants. Infect Immun (1978) 2.16

In vivo transduction with shiga toxin 1-encoding phage. Infect Immun (1998) 2.16

Genetic rearrangements in the rfb regions of Vibrio cholerae O1 and O139. Proc Natl Acad Sci U S A (1995) 2.15

New model for analysis of mucosal immunity: intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection. Infect Immun (1991) 2.14

Cloning of the Vibrio cholerae recA gene and construction of a Vibrio cholerae recA mutant. J Bacteriol (1986) 2.13

TnAraOut, a transposon-based approach to identify and characterize essential bacterial genes. Nat Biotechnol (2000) 2.11

Differential regulation of multiple flagellins in Vibrio cholerae. J Bacteriol (1998) 2.09

Production, characterization, and application of monoclonal antibodies to Vibrio cholerae O139 synonym Bengal. Clin Diagn Lab Immunol (1994) 2.07

Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance. Mol Microbiol (1995) 2.03

Comparison of immune responses in patients infected with Vibrio cholerae O139 and O1. Infect Immun (1997) 2.01

Analysis of clinical and environmental strains of nontoxigenic Vibrio cholerae for susceptibility to CTXPhi: molecular basis for origination of new strains with epidemic potential. Infect Immun (1998) 1.99

Antibodies directed against the toxin-coregulated pilus isolated from Vibrio cholerae provide protection in the infant mouse experimental cholera model. J Infect Dis (1990) 1.97

Genetic footprinting with mariner-based transposition in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2000) 1.95

Constitutive sensory transduction mutations in the Bordetella pertussis bvgS gene. J Bacteriol (1992) 1.91

Effects of changes in membrane sodium flux on virulence gene expression in Vibrio cholerae. Proc Natl Acad Sci U S A (1999) 1.90

Comparison of the vibriocidal antibody response in cholera due to Vibrio cholerae O139 Bengal with the response in cholera due to Vibrio cholerae O1. Clin Diagn Lab Immunol (1995) 1.89

Cholera toxin: genetic analysis, regulation, and role in pathogenesis. Curr Top Microbiol Immunol (1985) 1.89

Monoclonal immunoglobulin A prevents adherence and invasion of polarized epithelial cell monolayers by Salmonella typhimurium. Gastroenterology (1994) 1.85

Characterization of Vibrio cgolerae non-O1 serogroups obtained from an outbreak of diarrhea in Lima, Peru. J Clin Microbiol (1995) 1.82

Induction of the lysogenic phage encoding cholera toxin in naturally occurring strains of toxigenic Vibrio cholerae O1 and O139. Infect Immun (1998) 1.81

Vibrio cholerae O139 specific gene sequences. Lancet (1994) 1.80

Characterization of Vibrio cholerae bacteriophage K139 and use of a novel mini-transposon to identify a phage-encoded virulence factor. Mol Microbiol (1995) 1.80

Type 6 secretion dynamics within and between bacterial cells. Science (2012) 1.79

Molecular analysis of rRNA and cholera toxin genes carried by the new epidemic strain of toxigenic Vibrio cholerae O139 synonym Bengal. J Clin Microbiol (1994) 1.79

Simultaneous prevention of glutamine synthesis and high-affinity transport attenuates Salmonella typhimurium virulence. Infect Immun (1997) 1.77