Role of RpoS in virulence of pathogens.

ppGpp: magic beyond RNA polymerase. Nat Rev Microbiol (2012) 1.91

Evolution of virulence in opportunistic pathogens: generalism, plasticity, and control. Trends Microbiol (2012) 1.44

Borrelia burgdorferi requires the alternative sigma factor RpoS for dissemination within the vector during tick-to-mammal transmission. PLoS Pathog (2012) 1.20

The regulatory repertoire of Pseudomonas aeruginosa AmpC ß-lactamase regulator AmpR includes virulence genes. PLoS One (2012) 1.14

RpoS contributes to phagocyte oxidase-mediated stress resistance during urinary tract infection by Escherichia coli CFT073. MBio (2013) 0.92

RpoS plays a central role in the SOS induction by sub-lethal aminoglycoside concentrations in Vibrio cholerae. PLoS Genet (2013) 0.92

The novel sigma factor-like regulator RpoQ controls luminescence, chitinase activity, and motility in Vibrio fischeri. MBio (2012) 0.92

Evolution of the RpoS regulon: origin of RpoS and the conservation of RpoS-dependent regulation in bacteria. J Mol Evol (2010) 0.88

An RpoS-dependent sRNA regulates the expression of a chaperone involved in protein folding. RNA (2013) 0.87

Global repression of host-associated genes of the Lyme disease spirochete through post-transcriptional modulation of the alternative sigma factor RpoS. PLoS One (2014) 0.86

Transcriptome analysis of Vibrio parahaemolyticus in type III secretion system 1 inducing conditions. Front Cell Infect Microbiol (2014) 0.86

Differential gene expression and adherence of Escherichia coli O157:H7 in vitro and in ligated pig intestines. PLoS One (2011) 0.86

Mutations in global regulators lead to metabolic selection during adaptation to complex environments. PLoS Genet (2014) 0.85

Roles of RpoN in the resistance of Campylobacter jejuni under various stress conditions. BMC Microbiol (2011) 0.84

A proteomic analysis reveals differential regulation of the σ(S)-dependent yciGFE(katN) locus by YncC and H-NS in Salmonella and Escherichia coli K-12. Mol Cell Proteomics (2010) 0.84

Expanding the RpoS/σS-network by RNA sequencing and identification of σS-controlled small RNAs in Salmonella. PLoS One (2014) 0.83

Tissue-specific Salmonella Typhimurium gene expression during persistence in pigs. PLoS One (2011) 0.82

Transcriptional and Post-Transcriptional Modulation of SPI1 and SPI2 Expression by ppGpp, RpoS and DksA in Salmonella enterica sv Typhimurium. PLoS One (2015) 0.81

Fitness, stress resistance, and extraintestinal virulence in Escherichia coli. Infect Immun (2013) 0.81

Polymorphisms in rpoS and stress tolerance heterogeneity in natural isolates of Cronobacter sakazakii. Appl Environ Microbiol (2012) 0.81

Roles of rpoS-activating small RNAs in pathways leading to acid resistance of Escherichia coli. Microbiologyopen (2013) 0.80

A regulatory feedback loop between RpoS and SpoT supports the survival of Legionella pneumophila in water. Appl Environ Microbiol (2014) 0.79

IraL is an RssB anti-adaptor that stabilizes RpoS during logarithmic phase growth in Escherichia coli and Shigella. MBio (2014) 0.79

A distinct regulatory sequence is essential for the expression of a subset of nle genes in attaching and effacing Escherichia coli. J Bacteriol (2012) 0.79

Folate Acts in E. coli to Accelerate C. elegans Aging Independently of Bacterial Biosynthesis. Cell Rep (2016) 0.78

RpoS and indole signaling control the virulence of Vibrio anguillarum towards gnotobiotic sea bass (Dicentrarchus labrax) larvae. PLoS One (2014) 0.78

Characterising rhamnolipid production in Burkholderia thailandensis E264, a non-pathogenic producer. Appl Microbiol Biotechnol (2016) 0.78

Temperature-dependent expression of virulence genes in fish-pathogenic bacteria. Front Microbiol (2015) 0.78

Population genomics reveals additive and replacing horizontal gene transfers in the emerging pathogen Dickeya solani. BMC Genomics (2015) 0.78

The General Stress Response σS Is Regulated by a Partner Switch in the Gram-negative Bacterium Shewanella oneidensis. J Biol Chem (2016) 0.77

The rpoS gene is predominantly inactivated during laboratory storage and undergoes source-sink evolution in Escherichia coli species. J Bacteriol (2014) 0.77

Modification of the RpoS network with a synthetic small RNA. Nucleic Acids Res (2013) 0.77

Binding interface between the Salmonella σ(S)/RpoS subunit of RNA polymerase and Crl: hints from bacterial species lacking crl. Sci Rep (2015) 0.75

Proteome remodelling by the stress sigma factor RpoS/σ(S) in Salmonella: identification of small proteins and evidence for post-transcriptional regulation. Sci Rep (2017) 0.75

Transcriptome Analysis of the Intracellular Facultative Pathogen Piscirickettsia salmonis: Expression of Putative Groups of Genes Associated with Virulence and Iron Metabolism. PLoS One (2016) 0.75

Discrimination and Integration of Stress Signals by Pathogenic Bacteria. Cell Host Microbe (2016) 0.75

Competence for Genetic Transformation in Streptococcus pneumoniae: Mutations in σA Bypass the ComW Requirement for Late Gene Expression. J Bacteriol (2016) 0.75

Transcriptome changes associated with anaerobic growth in Yersinia intermedia (ATCC29909). PLoS One (2013) 0.75

RpoS-dependent expression of OsmY in Salmonella enterica serovar typhi: activation under stationary phase and SPI-2-inducing conditions. Curr Microbiol (2015) 0.75

RpoS role in virulence and fitness in enteropathogenic Escherichia coli. PLoS One (2017) 0.75

cAMP receptor protein regulates mouse colonization, motility, fimbria-mediated adhesion, and stress tolerance in uropathogenic Proteus mirabilis. Sci Rep (2017) 0.75

Hydrophobicity of Residue 128 of the Stress-Inducible Sigma Factor RpoS Is Critical for Its Activity. Front Microbiol (2017) 0.75

RpoS Affects Gene Expression in Salmonella enterica serovar Typhi Under Early Hyperosmotic Stress. Curr Microbiol (2017) 0.75

Identification of a central regulator of stationary-phase gene expression in Escherichia coli. Mol Microbiol (1991) 10.73

Induction of an outer surface protein on Borrelia burgdorferi during tick feeding. Proc Natl Acad Sci U S A (1995) 9.93

High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection. Science (2000) 9.14

Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae. Microbiol Mol Biol Rev (1998) 8.36

The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69. Mol Microbiol (1998) 6.38

The alternative sigma factor katF (rpoS) regulates Salmonella virulence. Proc Natl Acad Sci U S A (1992) 6.16

A hierarchical quorum-sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary-phase sigma factor RpoS. Mol Microbiol (1996) 6.07

The cellular concentration of the sigma S subunit of RNA polymerase in Escherichia coli is controlled at the levels of transcription, translation, and protein stability. Genes Dev (1994) 6.01

Signal transduction and regulatory mechanisms involved in control of the sigma(S) (RpoS) subunit of RNA polymerase. Microbiol Mol Biol Rev (2002) 5.60

Multiple sigma subunits and the partitioning of bacterial transcription space. Annu Rev Microbiol (2003) 5.36

Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proc Natl Acad Sci U S A (2004) 5.34

Genome-wide analysis of the general stress response network in Escherichia coli: sigmaS-dependent genes, promoters, and sigma factor selectivity. J Bacteriol (2005) 4.86

Citrobacter rodentium of mice and man. Cell Microbiol (2005) 4.76

Selective silencing of foreign DNA with low GC content by the H-NS protein in Salmonella. Science (2006) 4.60

Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc Natl Acad Sci U S A (1999) 4.42

Synthesis of the stationary-phase sigma factor sigma s is positively regulated by ppGpp. J Bacteriol (1993) 4.21

Trehalose synthesis genes are controlled by the putative sigma factor encoded by rpoS and are involved in stationary-phase thermotolerance in Escherichia coli. J Bacteriol (1991) 4.15

The molecular ecology of legionellae. Trends Microbiol (1996) 4.12

Acid and base resistance in Escherichia coli and Shigella flexneri: role of rpoS and growth pH. J Bacteriol (1994) 3.81

Functional modulation of Escherichia coli RNA polymerase. Annu Rev Microbiol (2000) 3.71

Expression of Borrelia burgdorferi OspC and DbpA is controlled by a RpoN-RpoS regulatory pathway. Proc Natl Acad Sci U S A (2001) 3.65

The RNA-binding protein HF-I, known as a host factor for phage Qbeta RNA replication, is essential for rpoS translation in Escherichia coli. Genes Dev (1996) 3.62

Large-scale monitoring of pleiotropic regulation of gene expression by the prokaryotic nucleoid-associated protein, H-NS. Mol Microbiol (2001) 3.60

The RNA chaperone Hfq is essential for the virulence of Salmonella typhimurium. Mol Microbiol (2006) 3.35

Curli fibers are highly conserved between Salmonella typhimurium and Escherichia coli with respect to operon structure and regulation. J Bacteriol (1998) 3.35

H-NS mediates the silencing of laterally acquired genes in bacteria. PLoS Pathog (2006) 3.29

The RpoS sigma factor relieves H-NS-mediated transcriptional repression of csgA, the subunit gene of fibronectin-binding curli in Escherichia coli. Mol Microbiol (1993) 3.18

Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi. Mol Microbiol (2000) 3.00

Salmonella: a model for bacterial pathogenesis. Annu Rev Med (2001) 2.99

Regulation of quorum sensing by RpoS in Pseudomonas aeruginosa. J Bacteriol (2000) 2.94

The response regulator RssB controls stability of the sigma(S) subunit of RNA polymerase in Escherichia coli. EMBO J (1996) 2.91

Molecular pathogenesis of Shigella spp.: controlling host cell signaling, invasion, and death by type III secretion. Clin Microbiol Rev (2008) 2.86

Vibrio cholerae hemagglutinin/protease, colonial variation, virulence, and detachment. Infect Immun (1992) 2.80

Quantitative control of the stationary phase-specific sigma factor, sigma S, in Escherichia coli: involvement of the nucleoid protein H-NS. EMBO J (1995) 2.78

Effect of rpoS mutation on the stress response and expression of virulence factors in Pseudomonas aeruginosa. J Bacteriol (1999) 2.72

The response regulator SprE controls the stability of RpoS. Proc Natl Acad Sci U S A (1996) 2.71

Regulation of proteolysis of the stationary-phase sigma factor RpoS. J Bacteriol (1998) 2.67

Association of nucleoid proteins with coding and non-coding segments of the Escherichia coli genome. Nucleic Acids Res (2006) 2.67

Role of rpoS in stress survival and virulence of Vibrio cholerae. J Bacteriol (1998) 2.65

The Pseudomonas aeruginosa RpoS regulon and its relationship to quorum sensing. Mol Microbiol (2004) 2.63

Role for the histone-like protein H-NS in growth phase-dependent and osmotic regulation of sigma S and many sigma S-dependent genes in Escherichia coli. J Bacteriol (1995) 2.55

Legionella pneumophila pathogesesis: a fateful journey from amoebae to macrophages. Annu Rev Microbiol (2000) 2.50

Control of sensitivity to inactivation by H2O2 and broad-spectrum near-UV radiation by the Escherichia coli katF locus. J Bacteriol (1986) 2.48

Virulent Salmonella typhimurium has two periplasmic Cu, Zn-superoxide dismutases. Proc Natl Acad Sci U S A (1999) 2.44

Transcriptional regulation of type III secretion genes in enteropathogenic Escherichia coli: Ler antagonizes H-NS-dependent repression. Mol Microbiol (2001) 2.43

Analysis of the RpoS regulon in Borrelia burgdorferi in response to mammalian host signals provides insight into RpoS function during the enzootic cycle. Mol Microbiol (2007) 2.32

The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi. Proc Natl Acad Sci U S A (2003) 2.31

Cloning of the egl gene of Pseudomonas solanacearum and analysis of its role in phytopathogenicity. J Bacteriol (1988) 2.31

Enteropathogenic Escherichia coli protein secretion is induced in response to conditions similar to those in the gastrointestinal tract. Infect Immun (1997) 2.23

The Pseudomonas aeruginosa lectins PA-IL and PA-IIL are controlled by quorum sensing and by RpoS. J Bacteriol (2000) 2.22

SigmaS-dependent gene expression at the onset of stationary phase in Escherichia coli: function of sigmaS-dependent genes and identification of their promoter sequences. J Bacteriol (2004) 2.17

Alternative sigma factors and their roles in bacterial virulence. Microbiol Mol Biol Rev (2005) 2.15

Reduced virulence of a hfq mutant of Pseudomonas aeruginosa O1. Microb Pathog (2003) 2.13

Escherichia coli histone-like protein H-NS preferentially binds to horizontally acquired DNA in association with RNA polymerase. DNA Res (2006) 2.11

Xenorhabdus nematophilus as a model for host-bacterium interactions: rpoS is necessary for mutualism with nematodes. J Bacteriol (2001) 2.10

Microarray analysis of RpoS-mediated gene expression in Escherichia coli K-12. Mol Genet Genomics (2004) 2.04

Silencing of xenogeneic DNA by H-NS-facilitation of lateral gene transfer in bacteria by a defense system that recognizes foreign DNA. Genes Dev (2007) 2.03

The Salmonella typhimurium katF (rpoS) gene: cloning, nucleotide sequence, and regulation of spvR and spvABCD virulence plasmid genes. J Bacteriol (1994) 1.94

RpoS is not central to the general stress response in Borrelia burgdorferi but does control expression of one or more essential virulence determinants. Infect Immun (2004) 1.94

New insights into transcriptional regulation by H-NS. Curr Opin Microbiol (2008) 1.93

Regulation of RpoS proteolysis in Escherichia coli: the response regulator RssB is a recognition factor that interacts with the turnover element in RpoS. Proc Natl Acad Sci U S A (1999) 1.88

RpoS controls the Vibrio cholerae mucosal escape response. PLoS Pathog (2006) 1.87

A two-component regulator induces the transmission phenotype of stationary-phase Legionella pneumophila. Mol Microbiol (2002) 1.87

Modelling infectious disease - time to think outside the box? Nat Rev Microbiol (2006) 1.82

Virulence and vaccine potential of Salmonella typhimurium mutants deficient in the expression of the RpoS (sigma S) regulon. Mol Microbiol (1996) 1.78

Role of sigma factor RpoS in initial stages of Salmonella typhimurium infection. Infect Immun (1997) 1.77

The Legionella pneumophila rpoS gene is required for growth within Acanthamoeba castellanii. J Bacteriol (1999) 1.76

RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase. Mol Microbiol (2001) 1.75

Impact of the RNA chaperone Hfq on the fitness and virulence potential of uropathogenic Escherichia coli. Infect Immun (2008) 1.65

Crl, a low temperature-induced protein in Escherichia coli that binds directly to the stationary phase sigma subunit of RNA polymerase. J Biol Chem (2004) 1.63

Interaction of Ler at the LEE5 (tir) operon of enteropathogenic Escherichia coli. Infect Immun (2003) 1.63

Insights into the complex regulation of rpoS in Borrelia burgdorferi. Mol Microbiol (2007) 1.54

Bicarbonate ion stimulates the expression of locus of enterocyte effacement-encoded genes in enterohemorrhagic Escherichia coli O157:H7. Infect Immun (2002) 1.54

Transcriptional regulation of the esp genes of enterohemorrhagic Escherichia coli. J Bacteriol (1999) 1.53

Central regulatory role for the RpoS sigma factor in expression of Salmonella dublin plasmid virulence genes. J Bacteriol (1995) 1.51

Altered stationary-phase response in a Borrelia burgdorferi rpoS mutant. J Bacteriol (2000) 1.49

Salmonella enterica serovar typhimurium strains with regulated delayed attenuation in vivo. Infect Immun (2008) 1.48

The rpoS gene from Yersinia enterocolitica and its influence on expression of virulence factors. Infect Immun (1995) 1.47

Salmonella enterica virulence genes are required for bacterial attachment to plant tissue. Appl Environ Microbiol (2005) 1.44

Heterogeneous surface expression of EspA translocon filaments by Escherichia coli O157:H7 is controlled at the posttranscriptional level. Infect Immun (2003) 1.41

Role for the Ankyrin eukaryotic-like genes of Legionella pneumophila in parasitism of protozoan hosts and human macrophages. Environ Microbiol (2008) 1.41

Salmonella enterica serovar Typhimurium response involved in attenuation of pathogen intracellular proliferation. Infect Immun (2001) 1.40

DNA looping-mediated repression by histone-like protein H-NS: specific requirement of Esigma70 as a cofactor for looping. Genes Dev (2005) 1.38

Role of RpoS in survival of Yersinia enterocolitica to a variety of environmental stresses. J Bacteriol (1995) 1.38

Lessons learned from the genome analysis of ralstonia solanacearum. Annu Rev Phytopathol (2004) 1.35

Characterization of a Legionella pneumophila relA insertion mutant and toles of RelA and RpoS in virulence gene expression. J Bacteriol (2002) 1.35

The putative sigma factor KatF (RpoS) is required for the transcription of the Salmonella typhimurium virulence gene spvB in Escherichia coli. FEMS Microbiol Lett (1992) 1.34

Evidence that RpoS (sigmaS) in Borrelia burgdorferi is controlled directly by RpoN (sigma54/sigmaN). J Bacteriol (2006) 1.34

ClpXP protease controls expression of the type III protein secretion system through regulation of RpoS and GrlR levels in enterohemorrhagic Escherichia coli. J Bacteriol (2005) 1.34

Role of histone-like proteins H-NS and StpA in expression of virulence determinants of uropathogenic Escherichia coli. J Bacteriol (2006) 1.34

Role of rpoS in acid resistance and fecal shedding of Escherichia coli O157:H7. Appl Environ Microbiol (2000) 1.32

Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells. Infect Immun (1996) 1.31

The Legionella pneumophila response regulator LqsR promotes host cell interactions as an element of the virulence regulatory network controlled by RpoS and LetA. Cell Microbiol (2007) 1.29

Ler and H-NS, regulators controlling expression of the long polar fimbriae of Escherichia coli O157:H7. J Bacteriol (2007) 1.29

Differential accumulation of Salmonella[Cu, Zn] superoxide dismutases SodCI and SodCII in intracellular bacteria: correlation with their relative contribution to pathogenicity. Mol Microbiol (2002) 1.27

Stationary phase reorganisation of the Escherichia coli transcription machinery by Crl protein, a fine-tuner of sigmas activity and levels. EMBO J (2007) 1.27

Artificial regulation of ospC expression in Borrelia burgdorferi. Mol Microbiol (2007) 1.26

Control of RpoS in global gene expression of Escherichia coli in minimal media. Mol Genet Genomics (2008) 1.26

RpoS regulation of gene expression during exponential growth of Escherichia coli K12. Mol Genet Genomics (2007) 1.25

rpoS gene function is a disadvantage for Escherichia coli BJ4 during competitive colonization of the mouse large intestine. Infect Immun (2000) 1.22

New developments and novel therapeutic perspectives for vitamin C. J Nutr (2007) 1.57

Regulators of oxidative stress response genes in Escherichia coli and their functional conservation in bacteria. Arch Biochem Biophys (2012) 1.34

Control of RpoS in global gene expression of Escherichia coli in minimal media. Mol Genet Genomics (2008) 1.26

RpoS regulation of gene expression during exponential growth of Escherichia coli K12. Mol Genet Genomics (2007) 1.25

RpoS-regulated genes of Escherichia coli identified by random lacZ fusion mutagenesis. J Bacteriol (2004) 1.16

Global effect of RpoS on gene expression in pathogenic Escherichia coli O157:H7 strain EDL933. BMC Genomics (2009) 1.10

Phenotypic diversity caused by differential RpoS activity among environmental Escherichia coli isolates. Appl Environ Microbiol (2011) 0.99

Rapid kinetic microassay for catalase activity. J Biomol Tech (2007) 0.99

Positive selection for loss of RpoS function in Escherichia coli. Mutat Res (2004) 0.96

Polymorphism and selection of rpoS in pathogenic Escherichia coli. BMC Microbiol (2009) 0.94

Role of RpoS in the virulence of Citrobacter rodentium. Infect Immun (2008) 0.92

Evolution of the RpoS regulon: origin of RpoS and the conservation of RpoS-dependent regulation in bacteria. J Mol Evol (2010) 0.88

Ascorbic acid synthesis due to L-gulono-1,4-lactone oxidase expression enhances NO production in endothelial cells. Biochem Biophys Res Commun (2006) 0.87

Stationary phase expression of the arginine biosynthetic operon argCBH in Escherichia coli. BMC Microbiol (2006) 0.84

Phylogenetic analysis and molecular signatures defining a monophyletic clade of heterocystous cyanobacteria and identifying its closest relatives. Photosynth Res (2014) 0.83

Controlled induction of the RpoS regulon in Escherichia coli, using an RpoS-expressing plasmid. Can J Microbiol (2003) 0.81

Functional rescue of vitamin C synthesis deficiency in human cells using adenoviral-based expression of murine l-gulono-gamma-lactone oxidase. Genomics (2004) 0.81

Controlled expression of an rpoS antisense RNA can inhibit RpoS function in Escherichia coli. Antimicrob Agents Chemother (2003) 0.81

Recent applications of engineered animal antioxidant deficiency models in human nutrition and chronic disease. J Nutr (2012) 0.79

Insertion/deletion-based approach for the detection of Escherichia coli O157:H7 in freshwater environments. Environ Sci Technol (2014) 0.78

Stationary phase-induction of G-->T mutations in Escherichia coli. Mutat Res (2006) 0.77

Can ageing-related degenerative diseases be ameliorated through administration of vitamin C at pharmacological levels? Med Hypotheses (2006) 0.76

Restoration of vitamin C synthesis in transgenic Gulo-/- mice by helper-dependent adenovirus-based expression of gulonolactone oxidase. Hum Gene Ther (2008) 0.76