Published in J Biol Chem on January 22, 1999
The role of incretins in glucose homeostasis and diabetes treatment. Pharmacol Rev (2008) 2.73
TRPM5 regulates glucose-stimulated insulin secretion. Pflugers Arch (2010) 1.74
Dense core secretory vesicles revealed as a dynamic Ca(2+) store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera. J Cell Biol (2001) 1.42
Cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate (NAADP) as messengers for calcium mobilization. J Biol Chem (2012) 1.37
Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells. Proc Natl Acad Sci U S A (2002) 1.29
Activation of Reg gene, a gene for insulin-producing beta -cell regeneration: poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosyl)ation. Proc Natl Acad Sci U S A (2001) 1.28
Signaling properties of CD38 in the mouse immune system: enzyme-dependent and -independent roles in immunity. Mol Med (2007) 1.24
Structure and enzymatic functions of human CD38. Mol Med (2007) 1.24
Adenosine 5-diphosphate-ribose is a neural regulator in primate and murine large intestine along with β-NAD(+). J Physiol (2012) 1.07
Molecular characterization of a novel intracellular ADP-ribosyl cyclase. PLoS One (2007) 1.03
Covalent and noncovalent intermediates of an NAD utilizing enzyme, human CD38. Chem Biol (2008) 0.98
CD38 is the major enzyme responsible for synthesis of nicotinic acid-adenine dinucleotide phosphate in mammalian tissues. Biochem J (2002) 0.97
Mechanism of cyclizing NAD to cyclic ADP-ribose by ADP-ribosyl cyclase and CD38. J Biol Chem (2009) 0.93
Activation of the GLP-1 receptor signalling pathway: a relevant strategy to repair a deficient beta-cell mass. Exp Diabetes Res (2011) 0.91
Monoclonal antibodies targeting CD38 in hematological malignancies and beyond. Immunol Rev (2016) 0.91
Mechanism-based small molecule probes for labeling CD38 on live cells. J Am Chem Soc (2009) 0.90
Implication of CD38 gene in podocyte epithelial-to-mesenchymal transition and glomerular sclerosis. J Cell Mol Med (2012) 0.90
Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Endolysosomal Two-pore Channels Modulate Membrane Excitability and Stimulus-Secretion Coupling in Mouse Pancreatic β Cells. J Biol Chem (2015) 0.89
An emerging role for NAADP-mediated Ca2+ signaling in the pancreatic β-cell. Islets (2010) 0.89
CD38/ADP-ribosyl cyclase: A new role in the regulation of osteoclastic bone resorption. J Cell Biol (1999) 0.87
Oxytocin receptor ligand binding in embryonic tissue and postnatal brain development of the C57BL/6J mouse. Front Behav Neurosci (2013) 0.86
Design, synthesis and biological characterization of novel inhibitors of CD38. Org Biomol Chem (2011) 0.83
CD38 in the nucleus accumbens and oxytocin are related to paternal behavior in mice. Mol Brain (2013) 0.83
Deletion of RAGE causes hyperactivity and increased sensitivity to auditory stimuli in mice. PLoS One (2009) 0.83
Cytosolic CD38 protein forms intact disulfides and is active in elevating intracellular cyclic ADP-ribose. J Biol Chem (2011) 0.83
The pathogenic relevance of the prognostic markers CD38 and CD49d in chronic lymphocytic leukemia. Ann Hematol (2013) 0.83
CD38 deficiency in the tumor microenvironment attenuates glioma progression and modulates features of tumor-associated microglia/macrophages. Neuro Oncol (2012) 0.82
A single residue in a novel ADP-ribosyl cyclase controls production of the calcium-mobilizing messengers cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate. J Biol Chem (2010) 0.81
Cluster of differentiation 38 (CD38) mediates bile acid-induced acinar cell injury and pancreatitis through cyclic ADP-ribose and intracellular calcium release. J Biol Chem (2013) 0.80
Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice. Front Neurosci (2016) 0.79
Identification of gene expression patterns crucially involved in experimental autoimmune encephalomyelitis and multiple sclerosis. Dis Model Mech (2016) 0.78
Anti-CD38 autoantibodies in type? diabetes. Diabetes Metab Res Rev (2006) 0.78
Immuno-targeting the multifunctional CD38 using nanobody. Sci Rep (2016) 0.77
CD38-mediated Ca(2+) signaling contributes to glucagon-induced hepatic gluconeogenesis. Sci Rep (2015) 0.76
The signaling protein CD38 is essential for early embryonic development. J Biol Chem (2012) 0.76
An immunohistochemical, enzymatic, and behavioral study of CD157/BST-1 as a neuroregulator. BMC Neurosci (2017) 0.75
Structure-specific effects of lipidated oxytocin analogs on intracellular calcium levels, parental behavior, and oxytocin concentrations in the plasma and cerebrospinal fluid in mice. Pharmacol Res Perspect (2017) 0.75
Cytosolic interaction of type III human CD38 with CIB1 modulates cellular cyclic ADP-ribose levels. Proc Natl Acad Sci U S A (2017) 0.75
Essential Bacillus subtilis genes. Proc Natl Acad Sci U S A (2003) 14.01
Bilirubin is an antioxidant of possible physiological importance. Science (1987) 11.26
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature (1998) 6.69
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med (2000) 6.27
A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology. Biochem Biophys Res Commun (1997) 5.25
Detection of the GBV-C hepatitis virus genome in serum from patients with fulminant hepatitis of unknown aetiology. Lancet (1995) 3.99
Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA. Proc Natl Acad Sci U S A (1997) 3.53
Cyclic ADP-ribose in insulin secretion from pancreatic beta cells. Science (1993) 3.26
Visualization of cranial motor neurons in live transgenic zebrafish expressing green fluorescent protein under the control of the islet-1 promoter/enhancer. J Neurosci (2000) 3.24
Infection with hepatitis GB virus C in patients on maintenance hemodialysis. N Engl J Med (1996) 3.13
Purification and properties of an enzyme, zymolyase, which lyses viable yeast cells. Arch Biochem Biophys (1972) 3.12
High-frequency generation of transgenic zebrafish which reliably express GFP in whole muscles or the whole body by using promoters of zebrafish origin. Dev Biol (1997) 3.03
Laparoscopic and endoscopic cooperative surgery for gastrointestinal stromal tumor dissection. Surg Endosc (2007) 2.77
cDNA cloning, sequence, and expression of carbonic anhydrase in Chlamydomonas reinhardtii: regulation by environmental CO2 concentration. Proc Natl Acad Sci U S A (1990) 2.71
A novel gene activated in regenerating islets. J Biol Chem (1988) 2.71
Production of 20-HETE and its role in autoregulation of cerebral blood flow. Circ Res (2000) 2.67
Comparison of the uptake of nitrate and ammonium by rice seedlings: influences of light, temperature, oxygen concentration, exogenous sucrose, and metabolic inhibitors. Plant Physiol (1978) 2.50
Silencing of retrotransposons in arabidopsis and reactivation by the ddm1 mutation. Plant Cell (2000) 2.50
High prevalence of anti-hepatitis B virus serological markers in patients with hepatitis C virus related chronic liver disease in Japan. Gut (1999) 2.46
Protein-bound acrolein: potential markers for oxidative stress. Proc Natl Acad Sci U S A (1998) 2.42
Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial. J Thromb Haemost (2006) 2.40
The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II. Genes Dev (1997) 2.38
Hepatitis C virus infection in spouses of patients with type C chronic liver disease. Ann Intern Med (1994) 2.38
Midline signals regulate retinal neurogenesis in zebrafish. Neuron (2000) 2.37
Hepatitis C virus infection in medical personnel after needlestick accident. Hepatology (1992) 2.37
Non-A, non-B hepatitis specific antibodies directed at host-derived epitope: implication for an autoimmune process. Lancet (1990) 2.35
Membrane currents of the tunicate egg under the voltage-clamp condition. J Physiol (1976) 2.32
A protein binding to the J kappa recombination sequence of immunoglobulin genes contains a sequence related to the integrase motif. Nature (1990) 2.29
Translational control of proinsulin synthesis by glucose. Nature (1980) 2.23
Two components of the calcium current in the egg cell membrane of the tunicate. J Physiol (1976) 2.22
Adenylylstreptomycin, a product of streptomycin inactivated by E. coli carrying R factor. J Antibiot (Tokyo) (1968) 2.19
FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development. Genes Dev (2000) 2.11
Properties of gastric smooth muscles obtained from mice which lack inositol trisphosphate receptor. J Physiol (2000) 2.11
Comparative evaluation of 99mTc-MIBI and 99mTc-HMDP scintimammography for the diagnosis of breast cancer and its axillary metastases. Eur J Nucl Med (2001) 2.09
Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice. J Clin Invest (2001) 2.07
Slow N-acetyltransferase 2 genotype affects the incidence of isoniazid and rifampicin-induced hepatotoxicity. Int J Tuberc Lung Dis (2000) 2.07
HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation. Cell (1998) 2.07
A new gene (alkB) of Escherichia coli that controls sensitivity to methyl methane sulfonate. J Bacteriol (1983) 2.06
Naturally occurring escape mutants of hepatitis B virus with various mutations in the S gene in carriers seropositive for antibody to hepatitis B surface antigen. J Virol (1994) 2.05
Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain. Proc Natl Acad Sci U S A (1988) 2.04
Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins. J Biol Chem (1998) 2.02
Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets. Nature (1981) 2.02
Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure. Circulation (2000) 2.01
Serum antibodies to carbonic anhydrase I and II in patients with idiopathic chronic pancreatitis and Sjögren's syndrome. Gastroenterology (1996) 2.01
Evaluation of epidermal growth factor receptor mutation status in serum DNA as a predictor of response to gefitinib (IRESSA). Br J Cancer (2007) 2.00
Influence of the genotypes of hepatitis C virus on the severity of recurrent liver disease after liver transplantation. Gastroenterology (1995) 2.00
Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma. Ann Allergy Asthma Immunol (2000) 1.99
Hyperpolarization of arterial smooth muscle induced by endothelial humoral substances. Am J Physiol (1991) 1.98
Escherichia coli gene that controls sensitivity to alkylating agents. J Bacteriol (1978) 1.96
Photo-mediated gene activation using caged RNA/DNA in zebrafish embryos. Nat Genet (2001) 1.95
Electrical properties of the epidermal stratum corneum. Med Biol Eng (1976) 1.94
A phytochrome from the fern Adiantum with features of the putative photoreceptor NPH1. Proc Natl Acad Sci U S A (1998) 1.93
Inhibition of macrophage migration by muramyl peptides. Infect Immun (1979) 1.91
Cloning, mapping, and characterization of the Escherichia coli prc gene, which is involved in C-terminal processing of penicillin-binding protein 3. J Bacteriol (1991) 1.91
A structurally flexible and antigenically variable N-terminal domain of the hepatitis C virus E2/NS1 protein: implication for an escape from antibody. Virology (1993) 1.90
Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteins. J Cell Biol (2000) 1.89
Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction. J Cereb Blood Flow Metab (1999) 1.87
p26 protein and 33-nm particle associated with nucleocapsid of hepatitis C virus recovered from the circulation of infected hosts. Virology (1992) 1.84
Functional repression of Islet-2 by disruption of complex with Ldb impairs peripheral axonal outgrowth in embryonic zebrafish. Neuron (2001) 1.83
Postoperative instillation of low-dose mitomycin C in the treatment of primary pterygium. Am J Ophthalmol (1988) 1.81
Hepatitis C virus variants from Vietnam are classifiable into the seventh, eighth, and ninth major genetic groups. Proc Natl Acad Sci U S A (1994) 1.81
Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia. J Cereb Blood Flow Metab (2001) 1.81
Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.79
Structure of the gene encoding beta-1,3-glucanase A1 of Bacillus circulans WL-12. Gene (1990) 1.79
Rapid disease progression correlates with instability of mutant SOD1 in familial ALS. Neurology (2005) 1.78
Cloning and sequence analysis of the gbpC gene encoding a novel glucan-binding protein of Streptococcus mutans. Infect Immun (1997) 1.75
Daily physical activity levels in preadolescent boys related to VO2max and lactate threshold. Eur J Appl Physiol Occup Physiol (1986) 1.75
Involvement of nicotinic acetylcholine receptors in suppression of antimicrobial activity and cytokine responses of alveolar macrophages to Legionella pneumophila infection by nicotine. J Immunol (2001) 1.74
Fortimicins A and B, new aminoglycoside antibiotics. I. Producing organism, fermentation and biological properties of fortimicins. J Antibiot (Tokyo) (1977) 1.74
Conformational rigidity of specific pyrimidine residues in tRNA arises from posttranscriptional modifications that enhance steric interaction between the base and the 2'-hydroxyl group. Biochemistry (1992) 1.73
Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma. Anal Biochem (1988) 1.73
Persistent and secondary adenovirus-mediated hepatic gene expression using adenovirus vector containing CTLA4IgG. Hum Gene Ther (1998) 1.72
Hepatitis C virus variants from Jakarta, Indonesia classifiable into novel genotypes in the second (2e and 2f), tenth (10a) and eleventh (11a) genetic groups. J Gen Virol (1996) 1.72
Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement. J Exp Med (1985) 1.72
Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27. Nature (1983) 1.71
Serological detection of hepatitis B virus genotypes by ELISA with monoclonal antibodies to type-specific epitopes in the preS2-region product. J Virol Methods (1999) 1.70
Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons. Science (1995) 1.70
Inactivation of the cholinesterase gene by Alu insertion: possible mechanism for human gene transposition. Proc Natl Acad Sci U S A (1991) 1.69
Biochemical and immunological characterization of the DNA binding protein (RBP-J kappa) to mouse J kappa recombination signal sequence. J Biochem (1992) 1.69
HCV genotypes in chronic hepatitis C and response to interferon. Lancet (1992) 1.67
Sustained esophageal contraction: a marker of esophageal chest pain identified by intraluminal ultrasonography. Gastroenterology (1999) 1.67
Detection and characterization of lipid hydroperoxides at picomole levels by high-performance liquid chromatography. Anal Biochem (1987) 1.67
Ionic currents through the membrane of the mammalian oocyte and their comparison with those in the tunicate and sea urchin. J Physiol (1977) 1.67
Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium. Proc Natl Acad Sci U S A (2000) 1.67
Studies on adenylylstreptomycin, a product of streptomycin inactivation by E. coli carrying the R-factor. J Antibiot (Tokyo) (1968) 1.66
Recent advances in the transition-metal-catalyzed regioselective approaches to polysubstituted benzene derivatives. Chem Rev (2000) 1.66
Hepatitis B virus strains with mutations in the core promoter in patients with fulminant hepatitis. Ann Intern Med (1995) 1.63
Identification of two distinct NADH oxidases corresponding to H2O2-forming oxidase and H2O-forming oxidase induced in Streptococcus mutans. J Gen Microbiol (1993) 1.61
Retrovirus long terminal repeats activate expression of coding sequences for the herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci U S A (1982) 1.61
Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene. J Biol Chem (1990) 1.60
Elevated chemokine levels in bronchoalveolar lavage fluid of tuberculosis patients. Am J Respir Crit Care Med (1997) 1.60
Production of interleukin-7 and interleukin-15 by fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum (1999) 1.60
Nucleotide sequence of a cloned hepatitis B virus genome, subtype ayr: comparison with genomes of the other three subtypes. J Gen Virol (1986) 1.59
Lysis of viable yeast cells by enzymes of Arthrobacter luteus. Arch Biochem Biophys (1971) 1.59
Hepatitis C virus variants from Nepal with novel genotypes and their classification into the third major group. J Gen Virol (1994) 1.59