Pharmacokinetics of a novel 5-lipoxygenase inhibitor (ABT-761) in pediatric patients with asthma.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 9923573)

Published in Eur J Clin Pharmacol on March 26, 1999

Authors

S L Wong1, G L Kearns, J P Kemp, J Drajesk, M Chang, C S Locke, L M Dube, W M Awni

Author Affiliations

1: Abbott Laboratories, Abbott Park, IL 60064-3500, USA. shekman.wong@abbott.com

Articles by these authors

(truncated to the top 100)

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy (2008) 12.35

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin. Nature (1985) 7.22

Cdc73p and Paf1p are found in a novel RNA polymerase II-containing complex distinct from the Srbp-containing holoenzyme. Mol Cell Biol (1997) 2.37

Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nat Genet (1999) 2.37

Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc Natl Acad Sci U S A (1995) 2.33

Oral montelukast compared with inhaled salmeterol to prevent exercise-induced bronchoconstriction. A randomized, double-blind trial. Exercise Study Group. Ann Intern Med (2000) 2.30

Ontogeny of dextromethorphan O- and N-demethylation in the first year of life. Clin Pharmacol Ther (2007) 2.17

Histone H2B repression causes cell-cycle-specific arrest in yeast: effects on chromosomal segregation, replication, and transcription. Cell (1987) 2.10

A comparison of salmeterol with albuterol in the treatment of mild-to-moderate asthma. N Engl J Med (1992) 2.10

Water is required for proton transfer from aspartate-96 to the bacteriorhodopsin Schiff base. Biochemistry (1991) 2.06

Continuous electronic heart rate monitoring for fetal assessment during labor. Cochrane Database Syst Rev (2001) 2.05

Wound hypoxia and acidosis limit neutrophil bacterial killing mechanisms. Arch Surg (1997) 1.96

Pharmacokinetic studies in paediatric patients. Clinical and ethical considerations. Clin Pharmacokinet (1992) 1.94

Pathways of proton release in the bacteriorhodopsin photocycle. Biochemistry (1992) 1.89

Properties of Asp212----Asn bacteriorhodopsin suggest that Asp212 and Asp85 both participate in a counterion and proton acceptor complex near the Schiff base. J Biol Chem (1991) 1.81

Pediatric acetaminophen overdose: risk factors associated with hepatocellular injury. Arch Pediatr Adolesc Med (2000) 1.80

Decreased activities of ubiquinol:ferricytochrome c oxidoreductase (complex III) and ferrocytochrome c:oxygen oxidoreductase (complex IV) in liver mitochondria from rats with hydroxycobalamin[c-lactam]-induced methylmalonic aciduria. J Biol Chem (1991) 1.80

Glucuronidation in humans. Pharmacogenetic and developmental aspects. Clin Pharmacokinet (1999) 1.79

Identification of a prodromal period in Crohn's disease but not ulcerative colitis. Am J Gastroenterol (2000) 1.77

First-pass metabolism of cyclosporin by the gut. Lancet (1991) 1.71

Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. Mol Genet Genomics (2002) 1.67

Cytochrome P450 3A: ontogeny and drug disposition. Clin Pharmacokinet (1999) 1.67

Pediatric Oncology Group (POG) studies of acute myeloid leukemia (AML): a review of four consecutive childhood AML trials conducted between 1981 and 2000. Leukemia (2005) 1.63

Acute hepatic failure associated with the use of sodium valproate. N Engl J Med (1979) 1.55

Impact of preexisting and induced humoral and cellular immune responses in an adenovirus-based gene therapy phase I clinical trial for localized mesothelioma. Hum Gene Ther (1998) 1.51

Effect of long-term salmeterol therapy compared with as-needed albuterol use on airway hyperresponsiveness. Chest (1999) 1.51

Acetaminophen-associated hepatic injury: evaluation of acetaminophen protein adducts in children and adolescents with acetaminophen overdose. Clin Pharmacol Ther (2008) 1.48

Clinical pharmacology: a discipline called to action for maternal and child health. Clin Pharmacol Ther (2007) 1.46

Multicenter, double-blind, placebo-controlled trial of terfenadine in seasonal allergic rhinitis and conjunctivitis. Ann Allergy (1985) 1.45

Antihistamines--is there anything safe to prescribe? Ann Allergy (1992) 1.44

Safety of salmeterol in the maintenance treatment of asthma. Ann Allergy Asthma Immunol (1995) 1.43

Transcriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4. Mol Cell Biol (2001) 1.43

Application of pharmacokinetics in the diagnosis of chemical abuse in Münchausen syndrome by proxy. Clin Pediatr (Phila) (1988) 1.38

An efficient system for the synthesis of bacteriorhodopsin in Halobacterium halobium. Gene (1990) 1.38

Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data. Pharmacogenetics (1999) 1.36

Constituents of red yeast rice, a traditional Chinese food and medicine. J Agric Food Chem (2000) 1.36

The responsiveness of disease-specific and generic health measures to changes in the severity of asthma among adults. Qual Life Res (1998) 1.35

Evaluation of the contralateral breast. The role of biopsy at the time of treatment of primary breast cancer. Ann Surg (1992) 1.34

CpG oligodeoxyribonucleotides rescue mature spleen B cells from spontaneous apoptosis and promote cell cycle entry. J Immunol (1998) 1.34

Identification of Enterococcus species and phenotypically similar Lactococcus and Vagococcus species by reverse checkerboard hybridization to chaperonin 60 gene sequences. J Clin Microbiol (2000) 1.34

The effect of inhibition of 5-lipoxygenase by zileuton in mild-to-moderate asthma. Ann Intern Med (1993) 1.32

Pharmacokinetics of ciprofloxacin in acutely ill and convalescent elderly patients. Am J Med (1987) 1.30

Acetaminophen overdose with therapeutic intent. J Pediatr (1998) 1.29

Evaluation of standard and active compression-decompression CPR in an acute human model of ventricular fibrillation. Circulation (1994) 1.28

Effect of ritonavir on the pharmacokinetics of ethinyl oestradiol in healthy female volunteers. Br J Clin Pharmacol (1998) 1.27

Cloning of a Ca(2+)-ATPase gene and the role of cytosolic Ca2+ in the gibberellin-dependent signaling pathway in aleurone cells. Plant J (1997) 1.27

Immediate action needed to improve labeling of prescription drugs for pediatric patients. Ann Pharmacother (1997) 1.25

Indoor and outdoor air quality investigation at schools in Hong Kong. Chemosphere (2000) 1.23

Vocal cord dysfunction in a child with asthma. J Asthma (1991) 1.23

Effect of omeprazole on concentrations of clarithromycin in plasma and gastric tissue at steady state. Antimicrob Agents Chemother (1995) 1.22

The chromosomal virulence gene, chvE, of Agrobacterium tumefaciens is regulated by a LysR family member. J Bacteriol (1993) 1.22

Developmental pharmacodynamics of cyclosporine. Clin Pharmacol Ther (1999) 1.22

Cefotaxime and desacetylcefotaxime pharmacokinetics in infants and children with meningitis. Antimicrob Agents Chemother (1985) 1.20

Basic fibroblast growth factor is neither necessary nor sufficient for the development of retinal neovascularization. Am J Pathol (1998) 1.20

Bacterial periorbital and orbital cellulitis in childhood. Ophthalmology (1983) 1.19

Dosing implications of altered gentamicin disposition in patients with cystic fibrosis. J Pediatr (1982) 1.19

Considerations in the rational design and conduct of phase I/II pediatric clinical trials: avoiding the problems and pitfalls. Clin Pharmacol Ther (2007) 1.18

Treatment of neonatal hypertension with enalaprilat. J Pediatr (1990) 1.17

The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population. Rheumatology (Oxford) (2006) 1.14

Debrancher deficiency: neuromuscular disorder in 5 adults. Ann Neurol (1979) 1.12

Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail". Clin Pharmacol Ther (2000) 1.12

Efficacy, disposition and pharmacodynamics of aspirin, acetaminophen and choline salicylate in young febrile children. Ther Drug Monit (1982) 1.12

Pharmacogenetics in pediatrics. Implications for practice. Pediatr Clin North Am (1997) 1.12

Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus. Diabetes Obes Metab (2011) 1.10

Single-dose, placebo-controlled comparative study of ibuprofen and acetaminophen antipyresis in children. J Pediatr (1991) 1.10

Mechanisms for the effects of fish oil lipid emulsions in the management of parenteral nutrition-associated liver disease. Prostaglandins Leukot Essent Fatty Acids (2013) 1.09

Cloning, expression, and regulation of rabbit cyclooxygenase-2 in renal medullary interstitial cells. Am J Physiol (1997) 1.09

The two consecutive M substates in the photocycle of bacteriorhodopsin are affected specifically by the D85N and D96N residue replacements. Photochem Photobiol (1992) 1.08

Repeated vaginal administration of trimeric HIV-1 clade C gp140 induces serum and mucosal antibody responses. Mucosal Immunol (2009) 1.06

Zafirlukast for symptomatic mild-to-moderate asthma: a 13-week multicenter study. The Zafirlukast Trialists Group. Clin Ther (1997) 1.06

Single-dose pharmacokinetics of ibuprofen and acetaminophen in febrile children. J Clin Pharmacol (1992) 1.06

BP1, a new homeobox gene, is frequently expressed in acute leukemias. Leukemia (2000) 1.05

Treatment of pain with gabapentin in a neonate. Pediatrics (2001) 1.05

Structures of aspartic acid-96 in the L and N intermediates of bacteriorhodopsin: analysis by Fourier transform infrared spectroscopy. Biochemistry (1992) 1.05

Retinal degeneration in transgenic mice with photoreceptor-specific expression of a dominant-negative fibroblast growth factor receptor. J Neurosci (1996) 1.05

Prognostic features in acute megakaryoblastic leukemia in children without Down syndrome: a report from the AML02 multicenter trial and the Children's Oncology Group Study POG 9421. Leukemia (2012) 1.03

Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19. Br J Clin Pharmacol (1997) 1.02

Effect of age on response to zafirlukast in patients with asthma in the Accolate Clinical Experience and Pharmacoepidemiology Trial (ACCEPT). Ann Allergy Asthma Immunol (2000) 1.02

The neurotoxicity of cyclotrimethylenetrinitramine (RDX) in a child: a clinical and pharmacokinetic evaluation. J Toxicol Clin Toxicol (1986) 1.01

Cocaine: clinical pharmacology and toxicology. J Pediatr (1989) 1.01

Specificity of ox brain triphosphoinositide phosphomonoesterase. Biochem Biophys Res Commun (1967) 1.01

Adenoma of the pigment epithelium of the ciliary body simulating a malignant melanoma. Am J Ophthalmol (1979) 1.01

Clathrin assembly protein AP-2 induces aggregation of membrane vesicles: a possible role for AP-2 in endosome formation. J Cell Biol (1992) 1.00

Endopyelotomy and endoureterotomy with the acucise ureteral cutting balloon device: preliminary experience. J Endourol (1993) 1.00

Quantitation of three-month intraindividual variability and influence of sex and menstrual cycle phase on CYP1A2, N-acetyltransferase-2, and xanthine oxidase activity determined with caffeine phenotyping. Clin Pharmacol Ther (1998) 0.99

Potent inhibition of cytochrome P-450 2D6-mediated dextromethorphan O-demethylation by terbinafine. Drug Metab Dispos (1999) 0.99

Measurement of acetaminophen-protein adducts in children and adolescents with acetaminophen overdoses. . J Clin Pharmacol (2001) 0.98

Dose-related protection of exercise bronchoconstriction by montelukast, a cysteinyl leukotriene-receptor antagonist, at the end of a once-daily dosing interval. Clin Pharmacol Ther (1997) 0.98

Effect of dosing schedule on efficacy of beclomethasone dipropionate aerosol in chronic asthma. Am Rev Respir Dis (1985) 0.97

A trial of zileuton versus mesalazine or placebo in the maintenance of remission of ulcerative colitis. The European Zileuton Study Group For Ulcerative Colitis. Gastroenterology (1997) 0.97

Five recombinant fragments of human serum albumin-tools for the characterization of the warfarin binding site. Protein Sci (2000) 0.97

Ibuprofen pharmacokinetics in preterm infants with patent ductus arteriosus. Clin Pharmacol Ther (2001) 0.97

Spatio-temporal distribution and characteristics of PAHs in sediments from Masan Bay, Korea. Mar Pollut Bull (2004) 0.96

An exact confidence interval from untransformed data for the ratio of two formulation means. J Pharmacokinet Biopharm (1984) 0.96

Pharmacokinetics and metabolism of oral midazolam in preterm infants. Br J Clin Pharmacol (2002) 0.96

Dose-ranging study of a new steroid for asthma: mometasone furoate dry powder inhaler. Respir Med (1999) 0.96

Montelukast dose selection in children ages 2 to 5 years: comparison of population pharmacokinetics between children and adults. J Clin Pharmacol (2001) 0.96

Orthotopic, but reversed implantation of the liver allograft in situs inversus totalis-a simple new approach to a difficult problem. Am J Transplant (2009) 0.96

The pharmacokinetics of antipyrine and three of its metabolites in the rabbit: intravenous administration of pure metabolites. Pharm Res (1991) 0.95

Single-dose pharmacokinetics of imipenem in children. J Pediatr (1984) 0.95