Published in Cell on August 01, 1978
Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate. Proc Natl Acad Sci U S A (1979) 72.18
Rapid transfer of DNA from agarose gels to nylon membranes. Nucleic Acids Res (1985) 21.05
Sequence organization and transcription at two heat shock loci in Drosophila. Proc Natl Acad Sci U S A (1978) 4.04
Amplification of genes for chorion proteins during oogenesis in Drosophila melanogaster. Proc Natl Acad Sci U S A (1980) 3.01
Structure and expression of ubiquitin genes of Drosophila melanogaster. Mol Cell Biol (1988) 2.32
Sequence arrangement and biological activity of cloned feline leukemia virus proviruses from a virus-productive human cell line. J Virol (1981) 2.17
Genetic Characterization of the 87c Region of the Third Chromosome of DROSOPHILA MELANOGASTER. Genetics (1979) 2.00
Differing levels of dispersed repetitive DNA among closely related species of Drosophila. Proc Natl Acad Sci U S A (1982) 1.94
Genomic deletions of the Drosophila melanogaster Hsp70 genes. Genetics (2004) 1.93
Towards a physical map of the Drosophila melanogaster genome: mapping of cosmid clones within defined genomic divisions. Nucleic Acids Res (1990) 1.87
Recurrent insertion and duplication generate networks of transposable element sequences in the Drosophila melanogaster genome. Genome Biol (2006) 1.81
Molecular genetics of herpes simplex virus: the terminal a sequences of the L and S components are obligatorily identical and constitute a part of a structural gene mapping predominantly in the S component. Proc Natl Acad Sci U S A (1979) 1.73
Molecular analysis of a gene in a developmentally regulated puff of Drosophila melanogaster. Proc Natl Acad Sci U S A (1980) 1.70
Two genes for the major heat-shock protein of Drosophila melanogaster arranged as an inverted repeat. Nucleic Acids Res (1980) 1.67
Organization of the multiple genes for the 70,000-dalton heat-shock protein in Drosophila melanogaster. Proc Natl Acad Sci U S A (1979) 1.55
Fate of viral DNA in nonpermissive cells infected with simian virus 40. Proc Natl Acad Sci U S A (1981) 1.51
Synthesis of low molecular weight heat shock peptides stimulated by ecdysterone in a cultured Drosophila cell line. Proc Natl Acad Sci U S A (1982) 1.50
Localization of the hsp83 transcript within a 3292 nucleotide sequence from the 63B heat shock locus of D. melanogaster. Nucleic Acids Res (1983) 1.50
Cloning and characterisation of the rRNA genes from the human malaria parasite Plasmodium falciparum. Nucleic Acids Res (1983) 1.47
Cdk7 is required for full activation of Drosophila heat shock genes and RNA polymerase II phosphorylation in vivo. Mol Cell Biol (2003) 1.39
Molecular analysis of the ecdysterone-inducible 2B5 "early' puff in Drosophila melanogaster. EMBO J (1986) 1.30
Effects of heat shock on gene expression and subcellular protein distribution in Chinese hamster ovary cells. Nucleic Acids Res (1979) 1.28
Text-mining assisted regulatory annotation. Genome Biol (2008) 1.26
Two closely linked transcription units within the 63B heat shock puff locus of D. melanogaster display strikingly different regulation. Nucleic Acids Res (1981) 1.24
Sequence heterogeneity, multiplicity, and genomic organization of alpha- and beta-tubulin genes in sea urchins. Mol Cell Biol (1981) 1.12
DNA sequence analysis reveals extensive homologies of regions preceding hsp70 and alphabeta heat shock genes in Drosophila melanogaster. Proc Natl Acad Sci U S A (1981) 1.08
Genomic organization and transcription of the alpha beta heat shock DNA in Drosophila melanogaster. Nucleic Acids Res (1981) 1.05
Loss of Hsp70 in Drosophila is pleiotropic, with effects on thermotolerance, recovery from heat shock and neurodegeneration. Genetics (2005) 1.04
Ectopic HP1 promotes chromosome loops and variegated silencing in Drosophila. EMBO J (2001) 1.03
Paucity of chimeric gene-transposable element transcripts in the Drosophila melanogaster genome. BMC Biol (2005) 1.00
Macromolecular requirements for abrogation of Fv-1 restriction by murine leukemia viruses. J Virol (1980) 0.95
Membrane association of a Staphylococcus aureus plasmid in Bacillus subtilis. J Bacteriol (1980) 0.90
Expression of the major heat shock gene of Drosophila melanogaster in Saccharomyces cerevisiae. Nucleic Acids Res (1986) 0.86
Genetics of the tubulin gene families of Physarum. Genetics (1984) 0.86
The alpha-tubulin gene family expressed during cell differentiation in Naegleria gruberi. J Cell Biol (1988) 0.77
Increased level of prolactin gene sequences in bromodeoxyuridine treated GH cells. Nucleic Acids Res (1982) 0.75
Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene. Proc Natl Acad Sci U S A (1975) 77.46
A system for mapping DNA sequences in the chromosomes of Drosophila melanogaster. Cell (1974) 27.33
Characterization of six cloned DNAs from Drosophila melanogaster, including one that contains the genes for rRNA. Cell (1975) 15.07
Chromosomal walking and jumping to isolate DNA from the Ace and rosy loci and the bithorax complex in Drosophila melanogaster. J Mol Biol (1983) 9.78
Molecular genetics of human color vision: the genes encoding blue, green, and red pigments. Science (1986) 8.23
Molecular Genetics of the Bithorax Complex in Drosophila melanogaster. Science (1983) 7.94
The RNA polymerase II molecule at the 5' end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged. Cell (1988) 7.23
R loop mapping of the 18S and 28S sequences in the long and short repeating units of Drosophila melanogaster rDNA. Cell (1977) 6.82
Repetitive sequences in isolated Thomas circles from Drosophila melanogaster. Cold Spring Harb Symp Quant Biol (1974) 6.72
Repeated gene families in Drosophila melanogaster. Cold Spring Harb Symp Quant Biol (1978) 5.85
The organization of the histone genes in Drosophila melanogaster: functional and evolutionary implications. Cold Spring Harb Symp Quant Biol (1978) 5.60
The units of DNA replication in Drosophila melanogaster chromosomes. Cold Spring Harb Symp Quant Biol (1974) 5.54
Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin. Cell (1983) 5.49
The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc Natl Acad Sci U S A (1991) 5.47
Molecular genetics of inherited variation in human color vision. Science (1986) 5.28
Germline transformation used to define key features of heat-shock response elements. Science (1988) 4.90
In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes. Proc Natl Acad Sci U S A (1993) 4.82
A new high-capacity cosmid vector and its use. Gene (1980) 4.72
Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation. Nature (1994) 4.57
Segmental distribution of bithorax complex proteins during Drosophila development. Nature (1985) 4.55
RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster cells. Mol Cell Biol (1986) 4.40
Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unit. Cell (1989) 4.11
New heat shock puffs and beta-galactosidase activity resulting from transformation of Drosophila with an hsp70-lacZ hybrid gene. Cell (1983) 4.06
Microarray analysis of Drosophila development during metamorphosis. Science (1999) 4.00
A novel arrangement of the 18S and 28S sequences in a repeating unit of Drosophila melanogaster rDNA. Cell (1977) 3.99
Fractionation of DNA fragments by polyethylene glycol induced precipitation. Methods Enzymol (1980) 3.93
Determinants of heat shock-induced chromosome puffing. Cell (1985) 3.91
Postinitiation transcriptional control in Drosophila melanogaster. Mol Cell Biol (1990) 3.83
High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation. Genes Dev (2000) 3.79
Translation of Drosophila melanogaster sequences in Escherichia coli. Proc Natl Acad Sci U S A (1977) 3.76
The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily. Cell (1991) 3.57
Letter: Potential biohazards of recombinant DNA molecules. Science (1974) 3.45
Effect of heat shock on the synthesis of low molecular weight RNAs in drosophilia: accumulation of a novel form of 5S RNA. Cell (1975) 3.41
Mechanism of DNA replication in Drosophila chromosomes: structure of replication forks and evidence for bidirectionality. Proc Natl Acad Sci U S A (1974) 3.29
Isolation and nucleotide sequence of the gene encoding human rhodopsin. Proc Natl Acad Sci U S A (1984) 3.27
Size fractionation of double-stranded DNA by precipitation with polyethylene glycol. Nucleic Acids Res (1975) 3.06
The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily. Genes Dev (1990) 3.01
Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells. Cell (1989) 3.00
The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins. Cell (1990) 2.87
Molecular organization of a Drosophila puff site that responds to ecdysone. Cell (1982) 2.81
Functional dissection of Ultrabithorax proteins in D. melanogaster. Cell (1990) 2.69
Protease activities during the course of sporulation on Bacillus subtilis. J Bacteriol (1971) 2.67
An expandable gene that encodes a Drosophila glue protein is not expressed in variants lacking remote upstream sequences. Cell (1982) 2.65
Topoisomerase I interacts with transcribed regions in Drosophila cells. Cell (1986) 2.65
DNA sequence requirements for generating paused polymerase at the start of hsp70. Genes Dev (1992) 2.63
Effect of polymorphism in the Drosophila regulatory gene Ultrabithorax on homeotic stability. Science (1996) 2.59
Novel transcripts from the Ultrabithorax domain of the bithorax complex. Genes Dev (1987) 2.58
Transcription properties of a cell type-specific TATA-binding protein, TRF. Cell (1997) 2.57
Rapid changes in Drosophila transcription after an instantaneous heat shock. Mol Cell Biol (1993) 2.57
A germline transformation analysis reveals flexibility in the organization of heat shock consensus elements. Nucleic Acids Res (1987) 2.48
Cooperative binding of Drosophila heat shock factor to arrays of a conserved 5 bp unit. Cell (1991) 2.48
Promoter melting and TFIID complexes on Drosophila genes in vivo. Genes Dev (1992) 2.35
Structure and expression of ubiquitin genes of Drosophila melanogaster. Mol Cell Biol (1988) 2.32
Structure and expression of a family of Ultrabithorax mRNAs generated by alternative splicing and polyadenylation in Drosophila. Genes Dev (1989) 2.30
HSF access to heat shock elements in vivo depends critically on promoter architecture defined by GAGA factor, TFIID, and RNA polymerase II binding sites. Genes Dev (1995) 2.22
RNA polymerase II pauses at the 5' end of the transcriptionally induced Drosophila hsp70 gene. Mol Cell Biol (1991) 2.18
Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms. Cell (1993) 2.17
Spatial and temporal pattern of hsp26 expression during normal development. EMBO J (1986) 2.14
In vivo interactions of RNA polymerase II with genes of Drosophila melanogaster. Mol Cell Biol (1985) 2.12
Short transcripts of the ternary complex provide insight into RNA polymerase II elongational pausing. J Mol Biol (1995) 2.12
Spatial and temporal patterns of E74 transcription during Drosophila development. Cell (1990) 2.11
DNA melting on yeast RNA polymerase II promoters. Science (1993) 2.10
Regulation and products of the Ubx domain of the bithorax complex. Cold Spring Harb Symp Quant Biol (1985) 2.06
Different cyclic AMP requirements for induction of the arabinose and lactose operons of Escherichia coli. J Mol Biol (1973) 2.04
The SR protein B52/SRp55 is essential for Drosophila development. Mol Cell Biol (1994) 2.02
Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock. Mol Cell (2001) 2.00
An Ultrabithorax protein binds sequences near its own and the Antennapedia P1 promoters. Cell (1988) 2.00
Characterization of a Drosophila protein associated with boundaries of transcriptionally active chromatin. Genes Dev (1991) 1.95
The position and orientation of genes in lambda and lambda dg DNA. Cold Spring Harb Symp Quant Biol (1966) 1.87
TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family. Proc Natl Acad Sci U S A (1999) 1.86
Direct cloning of DNA that interacts in vivo with a specific protein: application to RNA polymerase II and sites of pausing in Drosophila. Nucleic Acids Res (1998) 1.86
Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms. Cell (1997) 1.75
Dynamics of potentiation and activation: GAGA factor and its role in heat shock gene regulation. Nucleic Acids Res (1997) 1.72
Coordination of Drosophila metamorphosis by two ecdysone-induced nuclear receptors. Science (1997) 1.72
The large upstream control region of the Drosophila homeotic gene Ultrabithorax. Development (1991) 1.70
Molecular analysis of a gene in a developmentally regulated puff of Drosophila melanogaster. Proc Natl Acad Sci U S A (1980) 1.70
Cloning and characterization of nine heat-shock-induced mRNAs of Drosophila melanogaster. Gene (1981) 1.70
Detecting protein-DNA interactions in vivo: distribution of RNA polymerase on specific bacterial genes. Proc Natl Acad Sci U S A (1984) 1.68
Recruiting TATA-binding protein to a promoter: transcriptional activation without an upstream activator. Mol Cell Biol (1995) 1.67
Distribution of GAGA protein on Drosophila genes in vivo. Genes Dev (1995) 1.65
A specific RNA hairpin loop structure binds the RNA recognition motifs of the Drosophila SR protein B52. Mol Cell Biol (1997) 1.64
Transcriptional activation by the Antennapedia and fushi tarazu proteins in cultured Drosophila cells. Cell (1989) 1.63
The concentration of B52, an essential splicing factor and regulator of splice site choice in vitro, is critical for Drosophila development. Mol Cell Biol (1994) 1.62
RNA aptamers as effective protein antagonists in a multicellular organism. Proc Natl Acad Sci U S A (1999) 1.62
A TRF1:BRF complex directs Drosophila RNA polymerase III transcription. Cell (2000) 1.59
Molecular mapping of genetic and chromomeric units in Drosophila melanogaster. J Mol Biol (1983) 1.58
A hypersensitive site in hsp70 chromatin requires adjacent not internal DNA sequence. Nature (1985) 1.58
Dynamic protein-DNA architecture of a yeast heat shock promoter. Mol Cell Biol (1995) 1.58
High-resolution mapping of DNase I-hypersensitive sites of Drosophila heat shock genes in Drosophila melanogaster and Saccharomyces cerevisiae. Mol Cell Biol (1984) 1.58
Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo. Nature (1998) 1.57
Localization of the hsp83 transcript within a 3292 nucleotide sequence from the 63B heat shock locus of D. melanogaster. Nucleic Acids Res (1983) 1.50
Identification of homeotic target genes in Drosophila melanogaster including nervy, a proto-oncogene homologue. Genetics (1995) 1.48
Fine structure analyses of the Drosophila and Saccharomyces heat shock factor--heat shock element interactions. Nucleic Acids Res (1994) 1.47
Promoter sequence containing (CT)n.(GA)n repeats is critical for the formation of the DNase I hypersensitive sites in the Drosophila hsp26 gene. J Mol Biol (1992) 1.43
The regulatory region of the L-arabinose operon: a physical, genetic and physiological study. J Mol Biol (1975) 1.40
Optimal heat-induced expression of the Drosophila hsp26 gene requires a promoter sequence containing (CT)n.(GA)n repeats. J Mol Biol (1990) 1.35
Heat shock and developmental regulation of the Drosophila melanogaster hsp83 gene. Mol Cell Biol (1989) 1.35
The chromosomal arrangement of coding sequences in a family of repeated genes. Prog Nucleic Acid Res Mol Biol (1976) 1.35
The Drosophila E74 gene is required for metamorphosis and plays a role in the polytene chromosome puffing response to ecdysone. Development (1995) 1.34
Programmed cell death in the Drosophila CNS is ecdysone-regulated and coupled with a specific ecdysone receptor isoform. Development (1993) 1.32