Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas.

PubWeight™: 1.01‹?› | Rank: Top 15%

🔗 View Article (PMID 9950216)

Published in Cell Growth Differ on January 01, 1999

Authors

J A Meyerhardt1, K Caca, B C Eckstrand, G Hu, C Lengauer, S Banavali, A T Look, E R Fearon

Author Affiliations

1: Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109-0638, USA.

Articles citing this

Activation of the UNC5B receptor by Netrin-1 inhibits sprouting angiogenesis. Genes Dev (2007) 1.86

Neuronally expressed stem cell factor induces neural stem cell migration to areas of brain injury. J Clin Invest (2004) 1.85

Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism. Proc Natl Acad Sci U S A (2006) 1.85

A novel member of the netrin family, beta-netrin, shares homology with the beta chain of laminin: identification, expression, and functional characterization. J Cell Biol (2000) 1.59

Laminin-5 in epithelial tumour invasion. J Mol Histol (2004) 1.14

Netrins and their roles in placental angiogenesis. Biomed Res Int (2014) 0.83

Autocrine netrin function inhibits glioma cell motility and promotes focal adhesion formation. PLoS One (2011) 0.83

Guidance cue netrin-1 and the regulation of inflammation in acute and chronic kidney disease. Mediators Inflamm (2014) 0.81

Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer. Oncotarget (2016) 0.79

Characterization and expression of netrin-1 and its receptors UNC5B and DCC in human placenta. J Histochem Cytochem (2009) 0.78

Netrin-1 induces epithelial-mesenchymal transition and promotes hepatocellular carcinoma invasiveness. Dig Dis Sci (2014) 0.78

The neuroimmune guidance cue netrin-1: a new therapeutic target in cardiovascular disease. Am J Cardiovasc Dis (2013) 0.78

The use of early and midpoint adenoma-carcinoma sequence biomarkers in prediction of neoplastic progression in patients with a history of colorectal neoplasia. Dig Dis Sci (2006) 0.75

The Netrin-4/ Neogenin-1 axis promotes neuroblastoma cell survival and migration. Oncotarget (2016) 0.75

Articles by these authors

Genetic alterations during colorectal-tumor development. N Engl J Med (1988) 26.82

Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science (1998) 17.91

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science (1989) 11.53

Mutations of mitotic checkpoint genes in human cancers. Nature (1998) 11.20

Suppression of human colorectal carcinoma cell growth by wild-type p53. Science (1990) 11.18

Genes expressed in human tumor endothelium. Science (2000) 10.75

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science (1994) 10.45

Myb-related Schizosaccharomyces pombe cdc5p is structurally and functionally conserved in eukaryotes. Mol Cell Biol (1998) 10.34

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell (1985) 10.17

Prevalence of ras gene mutations in human colorectal cancers. Nature (1987) 9.23

14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Mol Cell (1997) 7.20

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science (1997) 6.50

Beta-globin locus is linked to the parathyroid hormone (PTH) locus and lies between the insulin and PTH loci in man. Proc Natl Acad Sci U S A (1983) 6.50

Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Invest (1999) 6.13

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature (1996) 6.11

Allelotype of colorectal carcinomas. Science (1989) 5.54

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature (1999) 5.44

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med (2000) 5.04

Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum Mol Genet (1998) 4.72

Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat Genet (1998) 4.67

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae. EMBO J (1995) 4.40

Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes. Cell Growth Differ (1990) 4.32

Clonal analysis using recombinant DNA probes from the X-chromosome. Cancer Res (1987) 4.25

Genetic instability and darwinian selection in tumours. Trends Cell Biol (1999) 4.12

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nat Genet (1996) 4.09

Human aminopeptidase N is a receptor for human coronavirus 229E. Nature (1992) 3.91

A phosphatase associated with metastasis of colorectal cancer. Science (2001) 3.86

Securin is required for chromosomal stability in human cells. Cell (2001) 3.71

Scrambled exons. Cell (1991) 3.65

The DCC protein and prognosis in colorectal cancer. N Engl J Med (1996) 3.51

Conversion of diploidy to haploidy. Nature (2000) 3.28

Mutations of GTBP in genetically unstable cells. Science (1995) 3.23

Chromosome segregation and cancer: cutting through the mystery. Nat Rev Cancer (2001) 3.11

Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression. Mol Cell Biol (1999) 3.08

Evidence for an age cutoff greater than 365 days for neuroblastoma risk group stratification in the Children's Oncology Group. J Clin Oncol (2005) 2.97

Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia. Nat Genet (2004) 2.96

CpG methylation is maintained in human cancer cells lacking DNMT1. Nature (2000) 2.94

Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours. Nature (1984) 2.77

Myelopoiesis in the zebrafish, Danio rerio. Blood (2001) 2.67

Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis. Cancer Res (2001) 2.65

Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms. N Engl J Med (1992) 2.64

SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Mol Cell (1999) 2.52

Use of restriction fragment length polymorphisms to determine the clonal origin of human tumors. Science (1985) 2.49

Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome. Proc Natl Acad Sci U S A (1998) 2.46

Age, body mass index and Type 2 diabetes-associations modified by ethnicity. Diabetologia (2003) 2.37

The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials. Genes Dev (1991) 2.34

Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins. Mol Cell Biol (1999) 2.30

Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma. Am J Pathol (1999) 2.30

Clinical and pathological associations with allelic loss in colorectal carcinoma [corrected]. JAMA (1989) 2.29

Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway. Genes Dev (1997) 2.26

Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas. Cancer Res (1993) 2.24

Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia. Science (1992) 2.19

Cell surface expression of v-fms-coded glycoproteins is required for transformation. Mol Cell Biol (1984) 2.09

Cellular DNA content as a predictor of response to chemotherapy in infants with unresectable neuroblastoma. N Engl J Med (1984) 2.09

Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism. Mol Cell Biol (1997) 2.04

Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors. Mol Cell Biol (2001) 2.03

Characterization of MAD2B and other mitotic spindle checkpoint genes. Genomics (1999) 2.01

New chromosomal translocations correlate with specific immunophenotypes of childhood acute lymphoblastic leukemia. Cell (1984) 1.99

Genomic organization, chromosomal localization, and independent expression of human cyclin D genes. Genomics (1992) 1.99

Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles. Am J Pathol (2001) 1.95

Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colon. Am J Pathol (2001) 1.95

Comparative genome map of human and cattle. Genomics (1995) 1.93

Molecular cytogenetic analysis of formalin-fixed, paraffin-embedded solid tumors by comparative genomic hybridization after universal DNA-amplification. Hum Mol Genet (1993) 1.91

Loss of genes on the short arm of chromosome 11 in bladder cancer. Nature (1985) 1.91

Characterization of human FAST-1, a TGF beta and activin signal transducer. Mol Cell (1998) 1.90

gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin. Genes Dev (2000) 1.89

Diverse mechanisms of beta-catenin deregulation in ovarian endometrioid adenocarcinomas. Cancer Res (2001) 1.87

Amplification of the gli gene in childhood sarcomas. Cancer Res (1989) 1.84

Intrinsic distribution of magnetic anisotropy in thin films probed by patterned nanostructures. Phys Rev Lett (2006) 1.84

Intracellular leucine zipper interactions suggest c-Myc hetero-oligomerization. Mol Cell Biol (1991) 1.84

Retrovirus-mediated gene transfer of NPM-ALK causes lymphoid malignancy in mice. Blood (1997) 1.83

Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes. Proc Natl Acad Sci U S A (1997) 1.82

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3. Proc Natl Acad Sci U S A (1995) 1.82

Characterization of human homologs of the Drosophila seven in absentia (sina) gene. Genomics (1997) 1.79

Expression profiling suggested a regulatory role of liver-enriched transcription factors in human hepatocellular carcinoma. Cancer Res (2001) 1.78

Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1). Mol Cell Biol (1994) 1.77

Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells. Leukemia (2012) 1.77

Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key! Blood (1993) 1.77

Carcinogen-specific induction of genetic instability. Proc Natl Acad Sci U S A (2001) 1.76

Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. MBio (2011) 1.76

Expression of c-met is a strong independent prognostic factor in breast carcinoma. Cancer (1998) 1.75

Molecular heterogeneity of inherited antithrombin III deficiency. N Engl J Med (1983) 1.75

[German S3-guideline "Diagnosis and treatment of esophagogastric cancer"]. Z Gastroenterol (2011) 1.74

Mechanisms underlying losses of heterozygosity in human colorectal cancers. Proc Natl Acad Sci U S A (2001) 1.68

Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect. N Engl J Med (1986) 1.67

Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67

Treatment of acute lymphoblastic leukaemia in countries with limited resources; lessons from use of a single protocol in India over a twenty year period [corrected]. Eur J Cancer (2005) 1.67

The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1. Oncogene (1996) 1.65

Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics. Leukemia (2009) 1.63

Carrier detection in X-linked agammaglobulinemia by analysis of X-chromosome inactivation. N Engl J Med (1987) 1.63

The v-fms oncogene induces factor independence and tumorigenicity in CSF-1 dependent macrophage cell line. Nature (1987) 1.61

Tandem linkage of human CSF-1 receptor (c-fms) and PDGF receptor genes. Cell (1988) 1.59

Indoor coal combustion emissions, GSTM1 and GSTT1 genotypes, and lung cancer risk: a case-control study in Xuan Wei, China. Cancer Epidemiol Biomarkers Prev (2000) 1.59

Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56