Published in Mol Biol Cell on February 01, 1999
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A (2001) 11.06
NF-kappaB and AP-1 connection: mechanism of NF-kappaB-dependent regulation of AP-1 activity. Mol Cell Biol (2004) 1.96
Salmonella-induced caspase-2 activation in macrophages: a novel mechanism in pathogen-mediated apoptosis. J Exp Med (2000) 1.79
Sphingosine kinase protects lipopolysaccharide-activated macrophages from apoptosis. Mol Cell Biol (2004) 1.12
NFkappaB in the mechanism of ammonia-induced astrocyte swelling in culture. J Neurochem (2008) 1.07
Sustained nitric oxide (NO)-releasing compound reverses dysregulated NO signal transduction in priapism. FASEB J (2013) 1.07
Requirement of the inducible nitric oxide synthase pathway for IL-1-induced osteoclastic bone resorption. Proc Natl Acad Sci U S A (2000) 0.98
Thioredoxin 1-mediated post-translational modifications: reduction, transnitrosylation, denitrosylation, and related proteomics methodologies. Antioxid Redox Signal (2011) 0.97
Nitric oxide (NO)-releasing statin derivatives, a class of drugs showing enhanced antiproliferative and antiinflammatory properties. Proc Natl Acad Sci U S A (2004) 0.94
Role of Rac and Cdc42 in lysophosphatidic acid-mediated cyclo-oxygenase-2 gene expression. Biochem J (2002) 0.89
Ergolide, sesquiterpene lactone from Inula britannica, inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-kappaB. Br J Pharmacol (2001) 0.86
Neuronal differentiation and protection from nitric oxide-induced apoptosis require c-Jun-dependent expression of NCAM140. Mol Cell Biol (2002) 0.84
Nitric oxide at a low concentration protects murine macrophage RAW264 cells against nitric oxide-induced death via cGMP signaling pathway. Br J Pharmacol (2003) 0.82
Nitric oxide and apoptosis induced in Peyer's patches by attenuated strains of Salmonella enterica serovar Enteritidis. Infect Immun (2002) 0.80
Beneficial effects of caffeic acid phenethyl ester in a rat model of vascular injury. Br J Pharmacol (2002) 0.79
Cytoplasmic translocation of high-mobility group box-1 protein is induced by diabetes and high glucose in retinal pericytes. Mol Med Rep (2016) 0.78
Cyclic GMP protects human macrophages against peroxynitrite-induced apoptosis. J Inflamm (Lond) (2009) 0.78
Anti-apoptotic mechanism of Bacoside rich extract against reactive nitrogen species induced activation of iNOS/Bax/caspase 3 mediated apoptosis in L132 cell line. Cytotechnology (2013) 0.77
Activation of c-Jun N-terminal kinase (JNK) signalling in experimentally induced gastric lesions in rats. Clin Exp Immunol (2006) 0.76
A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J (1956) 124.75
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell (1987) 20.61
Nitric oxide as a secretory product of mammalian cells. FASEB J (1992) 13.38
NF-kappa B: ten years after. Cell (1996) 12.80
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science (1996) 11.29
Mitogen-activated protein kinase pathways. Curr Opin Cell Biol (1997) 9.10
AP-1 function and regulation. Curr Opin Cell Biol (1997) 8.29
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell (1995) 6.69
Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. EMBO J (1995) 5.24
Biosynthesis and metabolism of endothelium-derived nitric oxide. Annu Rev Pharmacol Toxicol (1990) 5.14
Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem J (1996) 5.14
Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell (1994) 5.12
Nitric oxide activates cyclooxygenase enzymes. Proc Natl Acad Sci U S A (1993) 3.93
Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc Natl Acad Sci U S A (1994) 3.20
Inflammation, immunoregulation, and inducible nitric oxide synthase. J Leukoc Biol (1993) 3.07
Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration. Arch Biochem Biophys (1989) 3.07
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. J Clin Invest (1997) 2.99
Reactive oxygen species and programmed cell death. Trends Biochem Sci (1996) 2.68
Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells. J Biol Chem (1997) 2.66
Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells. J Biol Chem (1995) 2.60
Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J Immunol (1993) 2.59
An essential role for free radicals and derived species in signal transduction. FASEB J (1997) 2.50
Suppression of oncogene-induced transformation by a deletion mutant of c-jun. Oncogene (1993) 2.07
Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. J Exp Med (1998) 1.96
Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B. Proc Natl Acad Sci U S A (1995) 1.95
Activate NF-kappa B or die? Curr Biol (1997) 1.85
Mechanism of action of a dominant-negative mutant of c-Jun. Oncogene (1994) 1.81
Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta. Biochem Biophys Res Commun (1997) 1.63
Nitric oxide synthase induces macrophage death by apoptosis. Biochem Biophys Res Commun (1993) 1.63
Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway. Proc Natl Acad Sci U S A (1994) 1.59
Activation of human peripheral blood mononuclear cells by nitric oxide-generating compounds. J Immunol (1993) 1.53
Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer. FASEB J (1997) 1.50
v-src induction of the TIS10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element. Mol Cell Biol (1994) 1.42
Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis. Proc Natl Acad Sci U S A (1996) 1.40
Accommodation of vascularized xenografts: expression of "protective genes" by donor endothelial cells in a host Th2 cytokine environment. Nat Med (1997) 1.38
v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor. J Biol Chem (1995) 1.35
Manipulation of distinct NFkappaB proteins alters interleukin-1beta-induced human rheumatoid synovial fibroblast prostaglandin E2 formation. J Biol Chem (1996) 1.20
Pathways of peroxynitrite oxidation of thiol groups. Biochem J (1997) 1.19
Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression. FASEB J (1997) 1.16
Expression of mitogen-inducible cyclooxygenase induced by lipopolysaccharide: mediation through both mitogen-activated protein kinase and NF-kappaB signaling pathways in macrophages. Biochem Pharmacol (1997) 1.13
Nitric oxide and cGMP analogs activate transcription from AP-1-responsive promoters in mammalian cells. FASEB J (1995) 1.09
Nitric oxide-induced apoptosis in RAW 264.7 macrophages is antagonized by protein kinase C- and protein kinase A-activating compounds. Mol Pharmacol (1995) 1.09
Nuclear factor kB is activated by arachidonic acid but not by eicosapentaenoic acid. Biochem Biophys Res Commun (1996) 1.08
Prostanoid receptors of murine NIH 3T3 and RAW 264.7 cells. Structure and expression of the murine prostaglandin EP4 receptor gene. J Biol Chem (1996) 1.06
Cyclooxygenase-2: an essential regulator of NO-mediated apoptosis. FASEB J (1997) 1.05
Nitric oxide induced poly(ADP-ribose) polymerase cleavage in RAW 264.7 macrophage apoptosis is blocked by Bcl-2. FEBS Lett (1996) 1.05
Nitric oxide regulates nitric oxide synthase-2 gene expression by inhibiting NF-kappaB binding to DNA. Biochem J (1997) 1.03
Etoposide and cisplatin induced apoptosis in activated RAW 264.7 macrophages is attenuated by cAMP-induced gene expression. Oncogene (1998) 1.02
Nitric oxide amplifies interleukin 1-induced cyclooxygenase-2 expression in rat mesangial cells. J Clin Invest (1996) 0.99
Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators. J Clin Invest (1996) 0.99
Nitric oxide (NO) in apoptotic versus necrotic RAW 264.7 macrophage cell death: the role of NO-donor exposure, NAD+ content, and p53 accumulation. Arch Biochem Biophys (1996) 0.98
Co-stimulatory effect of nitric oxide on endothelial NF-kappaB implies a physiological self-amplifying mechanism. Eur J Immunol (1998) 0.95
Transcription factor decoy approach to decipher the role of NF-kappa B in oncogenesis. Anticancer Res (1996) 0.93
Activation of the NF-kappaB transcription factor in a T-lymphocytic cell line by hypochlorous acid. Biochem J (1997) 0.92
Tyrosine kinase inhibitors, genistein and herbimycin A, do not block interleukin-1 beta-induced activation of NF-kappa B in rat mesangial cells. Biochem Biophys Res Commun (1996) 0.89
Nitric oxide effects on cell growth: GMP-dependent stimulation of the AP-1 transcription complex and cyclic GMP-independent slowing of cell cycling. Br J Pharmacol (1997) 0.85
Involvement of a putative protein-tyrosine phosphatase and I kappa B-alpha serine phosphorylation in nuclear factor kappa B activation by tumor necrosis factor. J Biol Chem (1995) 0.84
The dual role of S-nitrosoglutathione (GSNO) during thymocyte apoptosis. Cell Signal (1996) 0.82
Synthesis of prostaglandin H synthase-2 by human alveolar macrophages in response to lipopolysaccharide is inhibited by decreased cell oxidant tone. J Biol Chem (1994) 0.82
Nitric oxide-induced S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase inhibits enzymatic activity and increases endogenous ADP-ribosylation. J Biol Chem (1992) 2.03
Nitric oxide causes ADP-ribosylation and inhibition of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem (1992) 1.60
Posttranslational modification of glyceraldehyde-3-phosphate dehydrogenase by S-nitrosylation and subsequent NADH attachment. J Biol Chem (1996) 1.58
Nitric oxide-induced S-glutathionylation and inactivation of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem (1999) 1.56
Accumulation of HIF-1alpha under the influence of nitric oxide. Blood (2001) 1.55
Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. Biochem J (1996) 1.50
p53 expression in nitric oxide-induced apoptosis. FEBS Lett (1994) 1.42
Interleukin-1 beta-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells. Exp Cell Res (1994) 1.28
Mechanism of covalent modification of glyceraldehyde-3-phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents. FEBS Lett (1994) 1.28
Extracellular ATP causes apoptosis and necrosis of cultured mesangial cells via P2Z/P2X7 receptors. Am J Physiol (1998) 1.28
Regulation of the hypoxia-inducible factor 1alpha by the inflammatory mediators nitric oxide and tumor necrosis factor-alpha in contrast to desferroxamine and phenylarsine oxide. J Biol Chem (2001) 1.24
Bcl-2 protects macrophages from nitric oxide-induced apoptosis. J Biol Chem (1996) 1.23
Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway. Biochem Biophys Res Commun (2000) 1.18
Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide. Biochem Biophys Res Commun (1997) 1.14
Activation of the cell death program by nitric oxide involves inhibition of the proteasome. J Biol Chem (1999) 1.12
Nitric oxide-induced apoptosis in RAW 264.7 macrophages is antagonized by protein kinase C- and protein kinase A-activating compounds. Mol Pharmacol (1995) 1.09
Cyclooxygenase-2: an essential regulator of NO-mediated apoptosis. FASEB J (1997) 1.05
Nitric oxide induced poly(ADP-ribose) polymerase cleavage in RAW 264.7 macrophage apoptosis is blocked by Bcl-2. FEBS Lett (1996) 1.05
Mass spectrometric analysis of nitric oxide-modified caspase-3. J Biol Chem (1999) 1.04
Delayed activation of PPARgamma by LPS and IFN-gamma attenuates the oxidative burst in macrophages. FASEB J (2001) 1.03
Etoposide and cisplatin induced apoptosis in activated RAW 264.7 macrophages is attenuated by cAMP-induced gene expression. Oncogene (1998) 1.02
Superoxide attenuates macrophage apoptosis by NF-kappa B and AP-1 activation that promotes cyclooxygenase-2 expression. J Immunol (1999) 0.99
Recognition of apoptotic cells by macrophages activates the peroxisome proliferator-activated receptor-gamma and attenuates the oxidative burst. Cell Death Differ (2005) 0.98
Nitric oxide (NO) in apoptotic versus necrotic RAW 264.7 macrophage cell death: the role of NO-donor exposure, NAD+ content, and p53 accumulation. Arch Biochem Biophys (1996) 0.98
Exogenous nitric oxide (NO) generation or IL-1 beta-induced intracellular NO production stimulates inhibitory auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase in RINm5F cells. J Immunol (1993) 0.98
Mechanisms for nitric oxide-induced cell death: involvement of apoptosis. Adv Neuroimmunol (1995) 0.96
Nitric oxide donors induce apoptosis in glomerular mesangial cells, epithelial cells and endothelial cells. Eur J Pharmacol (1996) 0.96
Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis. Biochemistry (1999) 0.95
Low-molecular-weight hyaluronic acid induces nuclear factor-kappaB-dependent resistance against tumor necrosis factor alpha-mediated liver injury in mice. Hepatology (2001) 0.93
Hypoxia and HIF-1alpha protect A549 cells from drug-induced apoptosis. Cell Death Differ (2006) 0.93
The balance between nitric oxide and superoxide determines apoptotic and necrotic death of rat mesangial cells. J Immunol (1997) 0.92
Overexpression of CuZn superoxide dismutase protects RAW 264.7 macrophages against nitric oxide cytotoxicity. Biochem J (1999) 0.92
Nitric oxide and superoxide inhibit platelet-derived growth factor receptor phosphotyrosine phosphatases. Free Radic Biol Med (1999) 0.91
Superoxide and nitric oxide--participation in cell communication. Cell Death Differ (2002) 0.90
U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activation. Exp Cell Res (1998) 0.90
p53 accumulation in apoptotic macrophages is an energy demanding process that precedes cytochrome c release in response to nitric oxide. Oncogene (1999) 0.88
Characterization of a nitric-oxide-catalysed ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase. Eur J Biochem (1992) 0.87
Reversible activation of soluble guanylate cyclase by oxidizing agents. Arch Biochem Biophys (1992) 0.86
Endotoxic shock leads to apoptosis in vivo and reduces Bcl-2. Shock (1996) 0.86
Attenuation of macrophage apoptosis by the cAMP-signaling system. Mol Cell Biochem (2000) 0.86
Heat shock proteins and macrophage resistance to the toxic effects of nitric oxide. Biochem J (1996) 0.86
Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis. Kidney Int (1997) 0.85
Apoptosis is triggered by the cyclic AMP signalling pathway in renal mesangial cells. FEBS Lett (1996) 0.85
Rapid and delayed p42/p44 mitogen-activated protein kinase activation by nitric oxide: the role of cyclic GMP and tyrosine phosphatase inhibition. J Immunol (1998) 0.84
The sulfhydryl reagent thimerosal elicits human platelet aggregation by mobilization of intracellular calcium and secondary prostaglandin endoperoxide formation. Biochem Biophys Res Commun (1989) 0.84
L-arginine stimulates an endogenous ADP-ribosyltransferase. Biochem Biophys Res Commun (1991) 0.83
The dual role of S-nitrosoglutathione (GSNO) during thymocyte apoptosis. Cell Signal (1996) 0.82
Modification of macrophage glyceraldehyde-3-phosphate dehydrogenase in response to nitric oxide. Eur J Pharmacol (1996) 0.82
The role of TRKA signaling in IL-10 production by apoptotic tumor cell-activated macrophages. Oncogene (2012) 0.82
Protease activation during nitric oxide-induced apoptosis: comparison between poly(ADP-ribose) polymerase and U1-70kDa cleavage. Eur J Pharmacol (1998) 0.82
Nitric oxide preferentially stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase compared to alcohol or lactate dehydrogenase. FEBS Lett (1993) 0.81
Redox regulation in acute and chronic inflammation. Cell Death Differ (2009) 0.81
Wortmannin interferes with thrombin-evoked secondary calcium redistribution in human platelets. Cell Signal (1997) 0.81
Attenuation of p53 expression and Bax down-regulation during phorbol ester mediated inhibition of apoptosis. Br J Pharmacol (1997) 0.80
The interaction of superoxide with nitric oxide destabilizes hypoxia-inducible factor-1alpha. Cell Mol Life Sci (2007) 0.80
NO-Evoked macrophage apoptosis is attenuated by cAMP-induced gene expression. Mol Med (1999) 0.80
Modulation of nitric oxide-evoked apoptosis by the p53-downstream target p21(WAF1/CIP1). J Leukoc Biol (2000) 0.80
Nitrosative and oxidative stress induced heme oxygenase-1 accumulation in rat mesangial cells. Eur J Pharmacol (1998) 0.79
Protection against nitric oxide-induced apoptosis in rat mesangial cells demands mitogen-activated protein kinases and reduced glutathione. Mol Pharmacol (1999) 0.78
Ebselen prevents inositol (1,4,5)-trisphosphate binding to its receptor. Biochem Pharmacol (1991) 0.78
Up-regulation of Bcl-2 by redox signals in glomerular mesangial cells. Cell Death Differ (2000) 0.78
Modulation of inducible nitric oxide synthase in RINm5F cells. Cell Signal (1994) 0.78
Efflux of cyclic GMP from activated human platelets. Mol Pharmacol (1993) 0.77
Superinduction of cyclooxygenase-2 by NO(*) and agonist challenge involves transcriptional regulation mediated by AP-1 activation. Biochemistry (2000) 0.77
Nitric oxide-induced F-actin disassembly is mediated via cGMP, cAMP, and protein kinase A activation in rat mesangial cells. Exp Cell Res (2001) 0.77
Apoptosis and expression of inducible nitric oxide synthase are mutually exclusive in renal mesangial cells. Am J Pathol (1997) 0.77
Activation of PPARgamma is not involved in butyrate-induced epithelial cell differentiation. Exp Cell Res (2005) 0.76
Redox regulation and the metabolic syndrome. Cell Death Differ (2011) 0.76
Physiological targets of superoxide anion and hydrogen peroxide in reperfusion injury. Free Radic Res Commun (1989) 0.75
Molecular actions of nitric oxide in mesangial cells. Histol Histopathol (2000) 0.75
Calabria: sun, sand, and cell death. Cell Death Differ (2002) 0.75
Modulation of glyceraldehyde-3-phosphate dehydrogenase in Salmonella abortus equi lipopolysaccharide-treated mice. Eur J Pharmacol (1994) 0.75
Redox regulation by ischemia/reperfusion. Cell Death Differ (2006) 0.75