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A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome (PLATO)
Clinical Trial ID NCT00391872
PubWeight™ 68.80
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🔗 Visit the ClinicalTrials.gov page for NCT00391872
Top papers
Rank
Title
Journal
Year
PubWeight™
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1
Ticagrelor versus clopidogrel in patients with acute coronary syndromes.
N Engl J Med
2009
18.03
2
Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study.
Lancet
2010
2.98
3
Cost-effectiveness of treating acute coronary syndrome patients with ticagrelor for 12 months: results from the PLATO study.
Eur Heart J
2012
2.16
4
Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: an analysis from the prospective, randomized PLATO trial.
Circulation
2013
2.03
5
Ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials.
Stroke
2013
1.99
6
Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial.
Eur Heart J
2011
1.98
7
Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial.
Circulation
2010
1.96
8
Association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from the platelet inhibition and patient outcomes trial.
Circulation
2012
1.84
9
Biomarkers in relation to the effects of ticagrelor in comparison with clopidogrel in non-ST-elevation acute coronary syndrome patients managed with or without in-hospital revascularization: a substudy from the Prospective Randomized Platelet Inhibition and Patient Outcomes (PLATO) trial.
Circulation
2013
1.77
10
Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial.
BMJ
2011
1.74
11
Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack.
Circulation
2012
1.66
12
Reduction in first and recurrent cardiovascular events with ticagrelor compared with clopidogrel in the PLATO Study.
Circulation
2012
1.62
13
Ticagrelor vs. clopidogrel in patients with non-ST-elevation acute coronary syndrome with or without revascularization: results from the PLATO trial.
Eur Heart J
2014
1.51
14
Economic analysis of ticagrelor therapy from a U.S. perspective: results from the PLATO study.
J Am Coll Cardiol
2015
1.48
15
Causes of mortality with ticagrelor compared with clopidogrel in acute coronary syndromes.
Heart
2014
1.46
16
Angiographic outcomes in the PLATO Trial (Platelet Inhibition and Patient Outcomes).
JACC Cardiovasc Interv
2013
1.46
17
Ticagrelor Versus Clopidogrel in Patients With Acute Coronary Syndromes and Chronic Obstructive Pulmonary Disease: An Analysis From the Platelet Inhibition and Patient Outcomes (PLATO) Trial.
J Am Heart Assoc
2015
1.46
18
Baseline Q waves as a prognostic modulator in patients with ST-segment elevation: insights from the PLATO trial.
CMAJ
2012
1.45
19
Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial.
Circulation
2011
1.33
20
Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis.
Circulation
2010
1.30
21
ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial: insights from the ECG substudy.
Circulation
2011
1.13
22
Importance of cardiovascular disease risk management in patients with type 2 diabetes mellitus.
Diabetes Metab Syndr Obes
2014
1.05
23
Prior smoking status, clinical outcomes, and the comparison of ticagrelor with clopidogrel in acute coronary syndromes-insights from the PLATelet inhibition and patient Outcomes (PLATO) trial.
Am Heart J
2012
0.96
24
Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: a substudy from the prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial.
Circ Cardiovasc Qual Outcomes
2012
0.96
25
The incidence of bradyarrhythmias and clinical bradyarrhythmic events in patients with acute coronary syndromes treated with ticagrelor or clopidogrel in the PLATO (Platelet Inhibition and Patient Outcomes) trial: results of the continuous electrocardiographic assessment substudy.
J Am Coll Cardiol
2011
0.94
26
Considerable variability in platelet activity among patients with coronary artery disease in response to an increased maintenance dose of clopidogrel.
Coron Artery Dis
2009
0.86
27
Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.
Eur Heart J
2015
0.86
28
Ticagrelor effects on myocardial infarction and the impact of event adjudication in the PLATO (Platelet Inhibition and Patient Outcomes) trial.
J Am Coll Cardiol
2014
0.85
29
Factors contributing to the lower mortality with ticagrelor compared with clopidogrel in patients undergoing coronary artery bypass surgery.
J Am Coll Cardiol
2012
0.84
30
Genome-wide association and Mendelian randomization study of NT-proBNP in patients with acute coronary syndrome.
Hum Mol Genet
2016
0.84
31
Cost-effectiveness of ticagrelor versus clopidogrel for the prevention of atherothrombotic events in adult patients with acute coronary syndrome in Germany.
Clin Res Cardiol
2013
0.83
32
Health economic analysis of ticagrelor in patients with acute coronary syndromes intended for non-invasive therapy.
Heart
2014
0.83
33
Growth differentiation factor-15 level predicts major bleeding and cardiovascular events in patients with acute coronary syndromes: results from the PLATO study.
Eur Heart J
2015
0.80
34
Biomarkers and Coronary Lesions Predict Outcomes after Revascularization in Non-ST-Elevation Acute Coronary Syndrome.
Clin Chem
2016
0.80
35
Safety and efficacy of ticagrelor and clopidogrel in primary percutaneous coronary intervention.
Heart
2016
0.79
36
Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared with clopidogrel: Data from the PLATO Trial.
Eur J Prev Cardiol
2014
0.79
37
Meta-analysis of intracranial hemorrhage in acute coronary syndromes: incidence, predictors, and clinical outcomes.
J Am Heart Assoc
2015
0.78
38
Ticagrelor versus clopidogrel in Asian patients with acute coronary syndrome: A retrospective analysis from the Platelet Inhibition and Patient Outcomes (PLATO) Trial.
Am Heart J
2015
0.77
39
Biomarkers for risk stratification of patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention: Insights from the Platelet Inhibition and Patient Outcomes trial.
Am Heart J
2015
0.77
40
Effect of ticagrelor on the outcomes of patients with prior coronary artery bypass graft surgery: insights from the PLATelet inhibition and patient outcomes (PLATO) trial.
Am Heart J
2013
0.76
41
The efficacy of ticagrelor is maintained in women with acute coronary syndromes participating in the prospective, randomized, PLATelet inhibition and patient Outcomes (PLATO) trial.
Eur Heart J
2014
0.76
42
Antiplatelet agents for chronic kidney disease.
Cochrane Database Syst Rev
2022
0.75
43
Baseline Q waves and time from symptom onset to ST-segment elevation myocardial infarction: insights from PLATO on the influence of sex.
Am J Med
2015
0.75
44
Relationship Between Early and Late Nonsustained Ventricular Tachycardia and Cardiovascular Death in Patients With Acute Coronary Syndrome in the Platelet Inhibition and Patient Outcomes (PLATO) Trial.
Circ Arrhythm Electrophysiol
2016
0.75
45
Extent of coronary artery disease and outcomes after ticagrelor administration in patients with an acute coronary syndrome: Insights from the PLATelet inhibition and patient Outcomes (PLATO) trial.
Am Heart J
2014
0.75
46
Long-term cost effectiveness of ticagrelor in patients with acute coronary syndromes in Thailand.
Health Econ Rev
2014
0.75
47
Response to letter regarding article, "Ticagrelor in patients with acute coronary syndromes and stroke: interpretation of subgroups in clinical trials".
Stroke
2013
0.75
48
Molecule of the month. Ticagrelor.
Drug News Perspect
2007
0.75
49
Outcome and causes of renal deterioration evaluated by serial cystatin C measurements in acute coronary syndrome patients -- results from the PLATelet inhibition and patient Outcomes (PLATO) study.
Am Heart J
2012
0.75
50
Ticagrelor for the treatment of atherosclerotic disease: insights from the PARTHENON clinical development program.
Future Cardiol
2016
0.75
51
Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial.
J Am Heart Assoc
2020
0.75
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