Published in Bone Marrow Transplant on April 01, 1999
Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells. J Exp Med (2002) 7.11
Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets. J Exp Med (2008) 3.48
Age-dependent incidence, time course, and consequences of thymic renewal in adults. J Clin Invest (2005) 2.84
Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool. J Clin Invest (2005) 2.48
T cell immune reconstitution following lymphodepletion. Semin Immunol (2007) 2.35
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. Nat Immunol (2009) 1.98
Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants. Blood (2009) 1.95
Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. Blood (2012) 1.85
Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study. Clin Infect Dis (2012) 1.62
Phase I study of recombinant human interleukin-7 administration in subjects with refractory malignancy. Clin Cancer Res (2010) 1.44
Recombinant interleukin-7 induces proliferation of naive macaque CD4+ and CD8+ T cells in vivo. J Virol (2004) 1.44
Reconstitution of the immune system after hematopoietic stem cell transplantation in humans. Semin Immunopathol (2008) 1.42
Plasma viremia and cellular HIV-1 DNA persist despite autologous hematopoietic stem cell transplantation for HIV-related lymphoma. J Acquir Immune Defic Syndr (2013) 1.34
Immune reconstitution and implications for immunotherapy following haematopoietic stem cell transplantation. Best Pract Res Clin Haematol (2008) 1.26
New approaches for preventing and treating chronic graft-versus-host disease. Blood (2005) 1.20
Antigen and lymphopenia-driven donor T cells are differentially diminished by post-transplantation administration of cyclophosphamide after hematopoietic cell transplantation. Biol Blood Marrow Transplant (2013) 1.16
Modulating T-cell homeostasis with IL-7: preclinical and clinical studies. J Intern Med (2009) 1.14
IL-7 differentially regulates cell cycle progression and HIV-1-based vector infection in neonatal and adult CD4+ T cells. Proc Natl Acad Sci U S A (2001) 1.10
IL-7 in human health and disease. Semin Immunol (2012) 1.08
Association of serum interleukin-7 levels with the development of acute graft-versus-host disease. J Clin Oncol (2008) 1.07
Interleukin-7 permits Th1/Tc1 maturation and promotes ex vivo expansion of cord blood T cells: a critical step toward adoptive immunotherapy after cord blood transplantation. Cancer Res (2010) 1.06
Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia. Arthritis Res Ther (2004) 1.04
Sustained CD4(+) T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide. Oncoimmunology (2014) 1.03
Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response. J Biol Chem (2010) 0.99
Acute inducible ablation of GRP78 reveals its role in hematopoietic stem cell survival, lymphogenesis and regulation of stress signaling. PLoS One (2012) 0.97
IL-7: the global builder of the innate lymphoid network and beyond, one niche at a time. Semin Immunol (2012) 0.94
Homeostatic T cell proliferation as a barrier to T cell tolerance. Philos Trans R Soc Lond B Biol Sci (2005) 0.91
Prevention of graft-versus-host disease by anti IL-7Ralpha antibody. Blood (2007) 0.91
History and current status of newborn screening for severe combined immunodeficiency. Semin Perinatol (2015) 0.89
Increased plasma-immune cytokines throughout the high-dose melphalan-induced lymphodepletion in patients with multiple myeloma: a window for adoptive immunotherapy. J Immunol (2009) 0.89
IL-7 production in murine lymphatic endothelial cells and induction in the setting of peripheral lymphopenia. Int Immunol (2013) 0.88
Chimeric SCID-hu Model as a Human Hematopoietic Stem Cell Host That Recapitulates the Effects of HIV-1 on Bone Marrow Progenitors in Infected Patients. J Stem Cells (2006) 0.88
Mechanism of Action of IL-7 and Its Potential Applications and Limitations in Cancer Immunotherapy. Int J Mol Sci (2015) 0.88
CD40 regulates human dendritic cell-derived IL-7 production that, in turn, contributes to CD8(+) T-cell antigen-specific expansion. Immunol Cell Biol (2008) 0.87
Cytopenia and leukocyte recovery shape cytokine fluctuations after myeloablative allogeneic hematopoietic stem cell transplantation. Haematologica (2011) 0.87
Different profiles of immune reconstitution in children and adults with HIV-infection after highly active antiretroviral therapy. BMC Infect Dis (2006) 0.87
Increased circulating interleukin-7 levels in HIV-1-infected women. J Acquir Immune Defic Syndr (2005) 0.87
Variations in serum IL-7 and 90K/Mac-2 binding protein (Mac-2 BP) levels analysed in cohorts of HIV-1 patients and correlated with clinical changes following antiretroviral therapy. Clin Exp Immunol (2001) 0.86
Suboptimal immune reconstitution in vertically HIV infected children: a view on how HIV replication and timing of HAART initiation can impact on T and B-cell compartment. Clin Dev Immunol (2012) 0.86
Increased interleukin-7 plasma levels are associated with recovery of CD4+ T cells in HIV-infected children. J Clin Immunol (2003) 0.85
T-lymphocyte recovery and function after cord blood transplantation. Immunol Res (2011) 0.85
Regulatory T cells in HIV infection: can immunotherapy regulate the regulator? Clin Dev Immunol (2012) 0.85
Kinetics of IL-7 and IL-15 levels after allogeneic peripheral blood stem cell transplantation following nonmyeloablative conditioning. PLoS One (2013) 0.84
Oral complications in hematopoietic stem cell recipients: the role of inflammation. Mediators Inflamm (2014) 0.84
The impact of chemotherapy-associated neutrophil/ lymphocyte counts on prognosis of adjuvant chemotherapy in colorectal cancer. BMC Cancer (2013) 0.84
Activation of islet autoreactive naïve T cells in infants is influenced by homeostatic mechanisms and antigen-presenting capacity. Diabetes (2013) 0.83
Increased bone marrow interleukin-7 (IL-7)/IL-7R levels but reduced IL-7 responsiveness in HIV-positive patients lacking CD4+ gain on antiviral therapy. PLoS One (2010) 0.83
Emergence of exhausted B cells in asymptomatic HIV-1-infected patients naïve for HAART is related to reduced immune surveillance. Clin Dev Immunol (2012) 0.82
Impact of chemotherapy for HIV-1 related lymphoma on residual viremia and cellular HIV-1 DNA in patients on suppressive antiretroviral therapy. PLoS One (2014) 0.81
IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway. PLoS One (2011) 0.81
Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection. PLoS One (2012) 0.79
The immunobiology of cord blood transplantation. Korean J Hematol (2010) 0.78
Redirecting the immune response: role of adoptive T cell therapy. Hum Gene Ther (2010) 0.77
Niche marketing: regulation of the homeostasis of naive CD4+ T cells. Nat Immunol (2009) 0.76
Rapid T cell repopulation after rabbit anti-thymocyte globulin (rATG) treatment is driven mainly by cytomegalovirus. Clin Exp Immunol (2012) 0.76
IL-7 and SCF Levels Inversely Correlate with T Cell Reconstitution and Clinical Outcomes after Cord Blood Transplantation in Adults. PLoS One (2015) 0.76
Adjuvant IL-7 potentiates adoptive T cell therapy by amplifying and sustaining polyfunctional antitumor CD4+ T cells. Sci Rep (2017) 0.75
Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science (1991) 8.85
T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates. Nat Med (1998) 3.95
Aberrations of suppressor T cells in human graft-versus-host disease. N Engl J Med (1979) 3.10
Severe combined immunodeficiency due to a specific defect in the production of interleukin-2. N Engl J Med (1990) 2.84
High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells. J Exp Med (1994) 2.70
Terminal deoxynucleotidyl transferase activity in human leukemic cells and in normal human thymocytes. N Engl J Med (1975) 2.69
Severe combined immunodeficiency and adenosine deaminase deficiency. N Engl J Med (1975) 2.35
Fatal crash involvement and laws against alcohol-impaired driving. J Public Health Policy (1989) 2.29
Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat Med (1995) 2.15
Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells. J Virol (1995) 1.90
Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome. J Exp Med (1984) 1.68
The application of bone marrow transplantation to the treatment of genetic diseases. Science (1986) 1.62
NHLBI workshop summary. Idiopathic pneumonia syndrome after bone marrow transplantation. Am Rev Respir Dis (1993) 1.54
Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome. Blood (1986) 1.53
Histiocytosis-X. N Engl J Med (1981) 1.51
Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7. Blood (1996) 1.49
Localization of a gene for Duane retraction syndrome to chromosome 2q31. Am J Hum Genet (1999) 1.46
Selection of patients for bone marrow transplantation in severe aplastic anemia. Blood (1975) 1.46
Graft-versus-host disease: an alternative hypothesis. Immunol Today (1989) 1.44
Correction of antigen-specific T-lymphocyte function by recombinant cytokines in children infected with human immunodeficiency virus type 1. J Pediatr (1992) 1.43
Abelson virus-transformed lymphocytes: null cells that modulate H-2. Cell (1977) 1.37
Posthepatitic severe aplastic anemia--an indication for early bone marrow transplantation. Blood (1974) 1.36
Complete correction of the Wiskott-Aldrich syndrome by allogeneic bone-marrow transplantation. N Engl J Med (1978) 1.35
Surface protein abnormalities in lymphocytes and platelets from patients with Wiskott-Aldrich syndrome. Lancet (1982) 1.33
A novel, myeloid transcription factor, C/EBP epsilon, is upregulated during granulocytic, but not monocytic, differentiation. Blood (1997) 1.29
Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes. J Exp Med (1995) 1.27
Morphology and lytic mechanisms of interleukin 3-dependent natural cytotoxic cells: tumor necrosis factor as a possible mediator. J Immunol (1986) 1.23
Concomitant presence of tumor-specific cytotoxic and inhibitor lymphocytes in patients with osteogenic sarcoma. N Engl J Med (1977) 1.22
Adenosine-deaminase deficiency in a child diagnosed prenatally. Lancet (1975) 1.22
Spontaneous apoptosis in lymphocytes from patients with Wiskott-Aldrich syndrome: correlation of accelerated cell death and attenuated bcl-2 expression. Blood (1999) 1.20
Altered O-glycan synthesis in lymphocytes from patients with Wiskott-Aldrich syndrome. J Exp Med (1991) 1.18
Radiosensitivity of thymic interleukin-7 production and thymopoiesis after bone marrow transplantation. Blood (2001) 1.14
Proliferative and interferon responses by peripheral blood mononuclear cells after bone marrow transplantation in humans. Infect Immun (1978) 1.13
Detection of leukemic cells in the CD34(+)CD38(-) bone marrow progenitor population in children with acute lymphoblastic leukemia. Blood (2001) 1.11
Murine sarcoma virus: the question of defectiveness. Science (1970) 1.10
Biosynthesis of C4 (fourth component of complement) by hybrids of C4-deficient guinea pig cells and HeLa cells. Science (1972) 1.09
Apoptosis and DNA damage in type 2 alveolar epithelial cells cultured from hyperoxic rats. Am J Physiol (1998) 1.09
T lymphocyte ontogeny in adenosine deaminase-deficient severe combined immune deficiency after treatment with polyethylene glycol-modified adenosine deaminase. J Clin Invest (1993) 1.09
Increased serum immunoglobulin E levels following allogeneic bone marrow transplantation. J Allergy Clin Immunol (1980) 1.09
Neonatal thymectomy: does it affect immune function? J Thorac Cardiovasc Surg (1998) 1.09
Tumor hybrid cells: an immunotherapeutic agent. J Natl Cancer Inst (1974) 1.06
Anti-recipient cytotoxic T lymphocyte precursors are present in the spleens of mice with acute graft versus host disease due to minor histocompatibility antigens. J Immunol (1981) 1.05
Studies on immunoglobulin gene rearrangement in formalin-fixed, paraffin-embedded pathology specimens. Am J Pathol (1988) 1.04
Acute graft-versus-host disease in recipients of bone-marrow transplants from identical twin donors. Lancet (1979) 1.04
Purine nucleoside metabolism in the erythrocytes of patients with adenosine deaminase deficiency and severe combined immunodeficiency. J Clin Invest (1976) 1.03
Isolation on discontinuous gradients of bovine albumin of a subpopulation of human lymphocytes exhibiting precursor characteristics. Eur J Immunol (1975) 1.03
ERK activation protects against DNA damage and apoptosis in hyperoxic rat AEC2. Am J Physiol (1999) 1.02
The pathophysiology and treatment of graft-versus-host disease. Clin Haematol (1983) 1.01
Clonal analysis of murine graft-vs-host disease. I. Phenotypic and functional analysis of T lymphocyte clones. J Immunol (1986) 0.99
T3-p28 is a protein associated with the delta and epsilon chains of the T cell receptor-T3 antigen complex during biosynthesis. J Biol Chem (1987) 0.99
The effect of thymic function on immunocompetence following bone marrow transplantation. Biol Blood Marrow Transplant (1995) 0.98
Cell-mediated cytotoxicity against skin fibroblasts in atopic dermatitis. J Immunol (1982) 0.97
Identification of a subpopulation of lymphocytes in human peripheral blood cytotoxic to autologous fibroblasts. J Exp Med (1976) 0.97
Clonal analysis of murine graft-vs-host disease. II. Leukokines that stimulate fibroblast proliferation and collagen synthesis in graft-vs. host disease. J Immunol (1986) 0.96
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes. Blood (1985) 0.94
Graft-versus-host disease after intrauterine and exchange transfusions for hemolytic disease of the newborn. N Engl J Med (1974) 0.94
Gene therapy in the United States: a five-year status report. Hum Gene Ther (1996) 0.94
Molecular heterogeneity of a lymphocyte glycoprotein in immunodeficient patients. J Clin Invest (1987) 0.93
Discontinuous density gradient analysis of human bone marrow: presence of alloantigen--responsive, PHA--unresponsive cells in norman bone marrow; absence of B lymphocytes in the bone marrow of patients with X--linked agammaglobulinemia. Clin Immunol Immunopathol (1974) 0.92
The control of autoreactivity. I. Lack of autoreactivity in murine spleens is due to concomitant presence of suppressor and autocytotoxic lymphocytes. J Immunol (1978) 0.91
IL-7 enhances the responsiveness of human T cells that develop in the bone marrow of athymic mice. J Immunol (2001) 0.91
The selective growth of murine newborn-derived suppressor cells and their probable mode of action. J Immunol (1986) 0.89
Hepatic veno-occlusive disease post-bone marrow transplantation in children conditioned with busulfan and cyclophosphamide: incidence, risk factors, and clinical outcome. Bone Marrow Transplant (1991) 0.89
Detection of genetically determined histocompatibility antigen differences between HL-A identical and MLC nonreactive siblings. Transplantation (1976) 0.89
T cell depleted haploidentical bone marrow transplantation for the treatment of children with severe combined immunodeficiency. Arch Immunol Ther Exp (Warsz) (2000) 0.88
Age, the thymus, and T lymphocytes. N Engl J Med (1995) 0.88
Regulation of human immunoglobulin E synthesis in acute graft versus host disease. J Clin Invest (1983) 0.88
In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling. Am J Physiol Lung Cell Mol Physiol (2004) 0.87
Discovery of a regulatory motif that controls the exposure of specific upstream cyclin-dependent kinase sites that determine both conformation and growth suppressing activity of pRb. J Biol Chem (1999) 0.87
The toxicity of human serum stored in flexible polyvinylchloride containers on human fibroblast cell cultures: an effect of di-2-ethylhexyl phthalate. Res Commun Chem Pathol Pharmacol (1974) 0.86
Pathological evidence of Wolman's disease following hematopoietic stem cell transplantation despite correction of lysosomal acid lipase activity. Bone Marrow Transplant (2009) 0.86
Immune abnormalities in patients lacking a lymphocyte surface glycoprotein. Clin Immunol Immunopathol (1984) 0.86
Application of bone marrow transplantation in genetic diseases. Clin Haematol (1983) 0.85
Abrogation of cyclin D1 expression predisposes lung cancer cells to serum deprivation-induced apoptosis. Am J Physiol (1999) 0.85
Immature T lymphocytes in the peripheral blood of bone marrow transplant recipients. Transplantation (1983) 0.85
Differential activation of the tyrosine kinases ZAP-70 and Syk after Fc gamma RI stimulation. Blood (1997) 0.85
Correction of infantile agranulocytosis (Kostmann's syndrome) by allogeneic bone marrow transplantation. Am J Med (1980) 0.85
Antithoracic duct lymphocyte globulin therapy of severe aplastic anemia. Blood (1983) 0.84
Membrane antigens of human bronchial epithelial cells identified by monoclonal antibodies. In Vitro Cell Dev Biol (1988) 0.83
Lymphocyte phenotype does not predict immune function in pediatric patients infected with human immunodeficiency virus type 1. J Pediatr (1989) 0.83
Bone marrow transplantation for the treatment of immune deficiency states. Bone Marrow Transplant (1990) 0.83
Umbilical cord blood cell transduction by retroviral vectors: preclinical studies to optimize gene transfer. Blood Cells (1994) 0.83
Human graft versus host disease. J Invest Dermatol (1980) 0.82
Allogeneic bone marrow transplantation for chronic granulomatous disease. J Pediatr (1982) 0.82
Acute and chronic graft-versus-host disease induced by minor histocompatibility antigens in mice. Transplantation (1983) 0.82
Gene therapy for adenosine deaminase deficiency. Annu Rev Med (2000) 0.81
Kinetics of the anti-recipient cytotoxic cell response of mice with minor histocompatibility antigen graft-vs-host disease. J Immunol (1982) 0.81
Whole antilymphocyte serum: a potent safe immunosuppressive agent for intravenous use in man. Transplant Proc (1977) 0.81