Published in Blood on June 26, 2007
Modulating T-cell homeostasis with IL-7: preclinical and clinical studies. J Intern Med (2009) 1.14
IL-7 in human health and disease. Semin Immunol (2012) 1.08
Association of serum interleukin-7 levels with the development of acute graft-versus-host disease. J Clin Oncol (2008) 1.07
Interleukin-7 permits Th1/Tc1 maturation and promotes ex vivo expansion of cord blood T cells: a critical step toward adoptive immunotherapy after cord blood transplantation. Cancer Res (2010) 1.06
Overcoming immunological barriers in regenerative medicine. Nat Biotechnol (2014) 1.02
Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease. J Immunol (2010) 0.96
Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease. Expert Opin Pharmacother (2008) 0.87
Nonalloreactive T cells prevent donor lymphocyte infusion-induced graft-versus-host disease by controlling microbial stimuli. J Immunol (2012) 0.82
IL-7 receptor blockade following T cell depletion promotes long-term allograft survival. J Clin Invest (2014) 0.81
Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2. Mol Ther (2015) 0.78
Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults. BMC Immunol (2014) 0.77
IL-7 and SCF Levels Inversely Correlate with T Cell Reconstitution and Clinical Outcomes after Cord Blood Transplantation in Adults. PLoS One (2015) 0.76
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med (2006) 14.33
Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo. Nat Immunol (2000) 12.81
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med (1994) 8.97
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med (1995) 7.52
Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells. J Exp Med (2002) 7.11
IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A (2001) 6.91
Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans. Cell (1993) 6.83
Cytokine control of memory T-cell development and survival. Nat Rev Immunol (2003) 5.99
Graft-versus-host disease. N Engl J Med (1991) 5.35
Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. J Exp Med (2002) 5.09
Expression and function of the interleukin 7 receptor in murine lymphocytes. Proc Natl Acad Sci U S A (1993) 4.35
Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nat Immunol (2003) 3.82
Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nat Med (2001) 3.69
Cytokine-induced survival of activated T cells in vitro and in vivo. Proc Natl Acad Sci U S A (1998) 2.71
Cytokine dysregulation and acute graft-versus-host disease. Blood (1992) 2.43
The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity (1997) 2.33
Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing. J Immunol (1996) 2.24
Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation. Blood (2001) 2.15
IL-7 is a growth and maintenance factor for mature and immature thymocyte subsets. Int Immunol (1989) 2.10
Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment. Proc Natl Acad Sci U S A (1998) 2.10
Serum levels of IL-7 in bone marrow transplant recipients: relationship to clinical characteristics and lymphocyte count. Bone Marrow Transplant (1999) 1.96
Impaired survival and proliferation in IL-7 receptor-deficient peripheral T cells. J Immunol (1996) 1.76
Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging. Blood (2006) 1.71
Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets. J Clin Invest (2000) 1.65
Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo. Immunity (1995) 1.56
Enhancement of thymopoiesis after bone marrow transplant by in vivo interleukin-7. Blood (1996) 1.49
In vivo use of monoclonal antibodies against murine T cell antigens. Clin Immunol Immunopathol (1989) 1.41
Interleukin 7: effects on early events in lymphopoiesis. Immunol Today (1989) 1.32
Cytokine dysregulation as a mechanism of graft versus host disease. Curr Opin Immunol (1993) 1.25
Alloreactive memory T cells are responsible for the persistence of graft-versus-host disease. J Immunol (2005) 1.17
Interleukin 7 worsens graft-versus-host disease. Blood (2002) 1.16
Thymic involution in murine graft-versus-host reaction. Epithelial injury mimicking human thymic dysplasia. Am J Pathol (1977) 1.15
Thymic atrophy in murine acute graft-versus-host disease is effected by impaired cell cycle progression of host pro-T and pre-T cells. Blood (2000) 1.06
Heparan sulfate proteoglycans mediate interleukin-7-dependent B lymphopoiesis. Blood (1999) 1.05
Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease. J Immunol (2004) 0.94
Recent advances in the treatment of graft-versus-host disease. Clin Med Res (2004) 0.92
Functional histology of the human thymus. Anat Embryol (Berl) (1991) 0.91
Allogeneic hematopoietic cell transplantation as treatment for hematological malignancies: a review. Springer Semin Immunopathol (2004) 0.89
T lymphocyte development and function in dogs with X-linked severe combined immunodeficiency. J Immunol (1994) 0.85
Role of T cell subsets in lethal graft-versus-host disease (GVHD) directed to class I versus class II H-2 differences. II. Protective effects of L3T4+ cells in anti-class II GVHD. J Immunol (1990) 0.85
Pericapillary collagen in the human thymus: implications for the concept of the 'blood-thymus' barrier. J Anat (1992) 0.79
[Structure and function of blood-tissue barriers]. Dtsch Med Wochenschr (2002) 0.79
A CD133-expressing murine liver oval cell population with bilineage potential. Stem Cells (2007) 1.87
Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. Blood (2012) 1.85
Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging. Blood (2006) 1.71
Successful immune reconstitution decreases leukemic relapse and improves survival in recipients of unrelated cord blood transplantation. Biol Blood Marrow Transplant (2006) 1.65
Keratinocyte growth factor preserves normal thymopoiesis and thymic microenvironment during experimental graft-versus-host disease. Blood (2002) 1.58
High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment. Proc Natl Acad Sci U S A (2011) 1.48
Isolation of a putative progenitor subpopulation of alveolar epithelial type 2 cells. Am J Physiol Lung Cell Mol Physiol (2003) 1.42
alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. Int J Cancer (2002) 1.36
Mouse mesenchymal stem cells expressing PAX-FKHR form alveolar rhabdomyosarcomas by cooperating with secondary mutations. Cancer Res (2008) 1.36
Distinct homeostatic requirements of CD4+ and CD4- subsets of Valpha24-invariant natural killer T cells in humans. Blood (2004) 1.32
Stem cell transplantation (cord blood transplants). Hematology Am Soc Hematol Educ Program (2004) 1.28
Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice. Am J Physiol Lung Cell Mol Physiol (2008) 1.22
Severe papillomavirus infection progressing to metastatic squamous cell carcinoma in bone marrow-transplanted X-linked SCID dogs. J Virol (2006) 1.20
Stable gene transfer to human CD34(+) hematopoietic cells using the Sleeping Beauty transposon. Exp Hematol (2006) 1.13
Human intrathymic lineage commitment is marked by differential CD7 expression: identification of CD7- lympho-myeloid thymic progenitors. Blood (2007) 1.12
Antigen-specific T-lymphocyte function after cord blood transplantation. Biol Blood Marrow Transplant (2006) 1.08
Contribution of proliferation and DNA damage repair to alveolar epithelial type 2 cell recovery from hyperoxia. Am J Physiol Lung Cell Mol Physiol (2005) 1.05
Progressive declines in neurocognitive function among survivors of hematopoietic stem cell transplantation for pediatric hematologic malignancies. J Pediatr Hematol Oncol (2008) 0.99
Human CD34(+) and CD34(+)CD38(-) hematopoietic progenitors in sickle cell disease differ phenotypically and functionally from normal and suggest distinct subpopulations that generate F cells. Exp Hematol (2004) 0.97
Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report. Blood (2006) 0.95
Bone marrow fails to differentiate into liver epithelium during murine development and regeneration. Hepatology (2007) 0.94
Retinoid-induced G1 arrest and differentiation activation are associated with a switch to cyclin-dependent kinase-activating kinase hypophosphorylation of retinoic acid receptor alpha. J Biol Chem (2002) 0.92
Importance of interleukin-7 in the development of experimental graft-versus-host disease. Biol Blood Marrow Transplant (2007) 0.91
The effects of Campath 1H upon graft-versus-host disease, infection, relapse, and immune reconstitution in recipients of pediatric unrelated transplants. Biol Blood Marrow Transplant (2007) 0.88
Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. J Exp Med (2013) 0.88
Transplantation of X-linked severe combined immunodeficient dogs with CD34+ bone marrow cells. Biol Blood Marrow Transplant (2002) 0.87
Successful hematopoietic stem cell transplantation for Niemann-Pick disease type B. Pediatrics (2005) 0.84
Safety of hematopoietic stem cell transplantation in children less than three years of age. Pediatr Hematol Oncol (2008) 0.81
Early use of drastic therapy. N Engl J Med (2005) 0.81
T cell repertoire development in XSCID dogs following nonconditioned allogeneic bone marrow transplantation. Biol Blood Marrow Transplant (2007) 0.80
Anti-CD52 antibody-mediated immune ablation with autologous immune recovery for the treatment of refractory juvenile polymyositis. J Clin Immunol (2011) 0.78
Genetic modification of airway progenitors after lentiviral gene delivery to the amniotic fluid of murine fetuses. Am J Respir Cell Mol Biol (2010) 0.77
Tolerance induction by lentiviral gene therapy with a nonmyeloablative regimen. Blood (2005) 0.76
Combined effects of interleukin-7 and stem cell factor administration on lymphopoiesis after murine bone marrow transplantation. Biol Blood Marrow Transplant (2010) 0.76
Pre- and post-natal treatment of hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer (2009) 0.75
Low doses of celecoxib attenuate gut barrier failure during experimental peritonitis. Lab Invest (2013) 0.75
Identification, functional analysis and expression in a heterotopic heart transplant model of CXCL9 in the rat. Immunology (2004) 0.75
Second hematopoietic stem cell transplantation in pediatric patients: overall survival and long-term follow-up. Biol Blood Marrow Transplant (2002) 0.75
[Transplantation of genetically modified cells in the treatment of children with SCID: great hopes and recent disappointments]. Med Wieku Rozwoj (2003) 0.75
Preponderant mitotic activity of nonleukemic cells plays an important role in failures to detect abnormal clone in childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol (2003) 0.75
[Treatment progress of Duchenne Muscular Dystrophy (DMD)]. Med Wieku Rozwoj (2004) 0.75
T lymphocyte abnormalities in juvenile systemic sclerosis patients. Clin Immunol (2013) 0.75