Published in Mol Cell Biol on July 01, 1999
Phosphoinositides: tiny lipids with giant impact on cell regulation. Physiol Rev (2013) 3.21
Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. Proc Natl Acad Sci U S A (2003) 2.89
Sorting it out: AP-2 and alternate clathrin adaptors in endocytic cargo selection. J Cell Biol (2003) 2.65
Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor. EMBO J (2002) 2.53
Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron (2008) 2.31
Substrate specificity of gamma-secretase and other intramembrane proteases. Cell Mol Life Sci (2008) 2.29
Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts. PLoS Comput Biol (2009) 1.90
Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage. Proc Natl Acad Sci U S A (2004) 1.76
The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway. EMBO J (2001) 1.72
Receptor clustering is involved in Reelin signaling. Mol Cell Biol (2004) 1.66
The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery. Proc Natl Acad Sci U S A (2002) 1.66
Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport. EMBO J (2002) 1.66
Regulated trafficking of the MSP/Eph receptor during oocyte meiotic maturation in C. elegans. Curr Biol (2008) 1.64
Reelin expression and glycosylation patterns are altered in Alzheimer's disease. Proc Natl Acad Sci U S A (2006) 1.57
Proteolytic processing of Alzheimer's β-amyloid precursor protein. J Neurochem (2011) 1.50
Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays. Mol Cell Biol (2006) 1.41
Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortex. Proc Natl Acad Sci U S A (2000) 1.36
Nck beta interacts with tyrosine-phosphorylated disabled 1 and redistributes in Reelin-stimulated neurons. Mol Cell Biol (2003) 1.34
The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor. EMBO J (2002) 1.34
The involvement of Reelin in neurodevelopmental disorders. Neuropharmacology (2012) 1.32
Endocytic adaptors--social networking at the plasma membrane. J Cell Sci (2011) 1.29
Biochemical and functional interaction of disrupted-in-schizophrenia 1 and amyloid precursor protein regulates neuronal migration during mammalian cortical development. J Neurosci (2010) 1.29
Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb. EMBO J (2000) 1.23
Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin. Biochem J (2000) 1.21
Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1. Biochem J (2004) 1.20
Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibody. Proc Natl Acad Sci U S A (2000) 1.18
Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway. J Biol Chem (2009) 1.16
The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains. Mol Neurodegener (2009) 1.12
Long-term prevention of Alzheimer's disease-like behavioral deficits in PDAPP mice carrying a mutation in Asp664. Behav Brain Res (2008) 1.12
Structural basis of SNT PTB domain interactions with distinct neurotrophic receptors. Mol Cell (2000) 1.10
Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network. Mol Biol Cell (2007) 1.09
Differential functions of ApoER2 and very low density lipoprotein receptor in Reelin signaling depend on differential sorting of the receptors. J Biol Chem (2009) 1.08
A genetic interaction between the APP and Dab1 genes influences brain development. Mol Cell Neurosci (2007) 1.08
Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family. Biol Chem (2010) 1.07
The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis. Mol Biol Cell (2008) 1.05
Identification of a major cyclic AMP-dependent protein kinase A phosphorylation site within the cytoplasmic tail of the low-density lipoprotein receptor-related protein: implication for receptor-mediated endocytosis. Mol Cell Biol (2001) 1.02
Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1. BMC Dev Biol (2008) 0.99
Gleevec increases levels of the amyloid precursor protein intracellular domain and of the amyloid-beta degrading enzyme neprilysin. Mol Biol Cell (2007) 0.99
Reconstitution of the Reelin signaling pathway in fibroblasts demonstrates that Dab1 phosphorylation is independent of receptor localization in lipid rafts. Mol Cell Biol (2006) 0.98
Functional roles of short sequence motifs in the endocytosis of membrane receptors. Front Biosci (Landmark Ed) (2009) 0.94
Mouse disabled 1 regulates the nuclear position of neurons in a Drosophila eye model. Mol Cell Biol (2006) 0.94
Reversal of learning deficits in hAPP transgenic mice carrying a mutation at Asp664: a role for early experience. Behav Brain Res (2009) 0.94
Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR. EMBO J (2007) 0.93
Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans. Genes Dev (2003) 0.93
Disabled-2 heterozygous mice are predisposed to endometrial and ovarian tumorigenesis and exhibit sex-biased embryonic lethality in a p53-null background. Am J Pathol (2006) 0.92
Amyloid precursor protein mediates a tyrosine kinase-dependent activation response in endothelial cells. J Neurosci (2009) 0.91
Analysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related protein. Biochem J (2001) 0.90
Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling. J Toxicol (2012) 0.90
Amyloid precursor protein mediates monocyte adhesion in AD tissue and apoE(-)/(-) mice. Neurobiol Aging (2008) 0.90
Molecular mechanisms of SH2- and PTB-domain-containing proteins in receptor tyrosine kinase signaling. Cold Spring Harb Perspect Biol (2013) 0.89
The generation and function of soluble apoE receptors in the CNS. Mol Neurodegener (2006) 0.89
Reelin signaling in development, maintenance, and plasticity of neural networks. Ageing Res Rev (2013) 0.87
Phospholipid transfer protein reduces phosphorylation of tau in human neuronal cells. J Neurosci Res (2009) 0.85
p67 isoform of mouse disabled 2 protein acts as a transcriptional activator during the differentiation of F9 cells. Biochem J (2000) 0.85
The role of lipoprotein receptors on the physiological function of APP. Exp Brain Res (2011) 0.84
Macrophage VLDL receptor promotes PAFAH secretion in mother's milk and suppresses systemic inflammation in nursing neonates. Nat Commun (2012) 0.84
Identification of alternatively spliced dab1 isoforms in zebrafish. Dev Genes Evol (2006) 0.84
Identification of alternatively spliced Dab1 and Fyn isoforms in pig. BMC Neurosci (2011) 0.83
Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance. PLoS One (2013) 0.83
The role of Vldlr in intraretinal angiogenesis in mice. Invest Ophthalmol Vis Sci (2011) 0.82
The inositol phosphatase SHIP-1 inhibits NOD2-induced NF-κB activation by disturbing the interaction of XIAP with RIP2. PLoS One (2012) 0.81
The amyloid precursor protein intracellular domain-fe65 multiprotein complexes: a challenge to the amyloid hypothesis for Alzheimer's disease? Int J Alzheimers Dis (2012) 0.81
Both the phosphoinositide and receptor binding activities of Dab1 are required for Reelin-stimulated Dab1 tyrosine phosphorylation. Brain Res Mol Brain Res (2005) 0.81
Sulfatides partition disabled-2 in response to platelet activation. PLoS One (2009) 0.81
Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice. PLoS One (2012) 0.80
Adapting for endocytosis: roles for endocytic sorting adaptors in directing neural development. Front Cell Neurosci (2015) 0.79
Splice-mediated motif switching regulates disabled-1 phosphorylation and SH2 domain interactions. Mol Cell Biol (2012) 0.79
RNAi-mediated knock-down of Dab and Numb attenuate Aβ levels via γ-secretase mediated APP processing. Transl Neurodegener (2012) 0.79
Serine phosphorylation regulates disabled-1 early isoform turnover independently of Reelin. Cell Signal (2010) 0.79
New Insights into Reelin-Mediated Signaling Pathways. Front Cell Neurosci (2016) 0.78
Reelin-mediated Signaling during Normal and Pathological Forms of Aging. Aging Dis (2010) 0.78
CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development. Neuron (2017) 0.77
Amyloid precursor family proteins are expressed by thymic and lymph node stromal cells but are not required for lymphocyte development. Int Immunol (2009) 0.77
Canonical and Non-canonical Reelin Signaling. Front Cell Neurosci (2016) 0.77
Localization of reelin signaling pathway components in murine midbrain and striatum. Cell Tissue Res (2014) 0.76
Effects of electromagnetic fields on reelin and Dab1 expression in the developing cerebral cortex. Neurol Sci (2014) 0.76
The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila. Development (2017) 0.76
Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain. Sci Rep (2017) 0.75
Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses. J Biol Chem (2016) 0.75
C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus. J Neurosci (2017) 0.75
How does Reelin signaling regulate the neuronal cytoskeleton during migration? Neurogenesis (Austin) (2016) 0.75
Functional Roles of the Interaction of APP and Lipoprotein Receptors. Front Mol Neurosci (2017) 0.75
Fyn tyrosine kinase increases Apolipoprotein E Receptor 2 levels and phosphorylation. PLoS One (2014) 0.75
Possible Involvement of Standardized Bacopa monniera Extract (CDRI-08) in Epigenetic Regulation of reelin and Brain-Derived Neurotrophic Factor to Enhance Memory. Front Pharmacol (2016) 0.75
Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell (1993) 16.91
Protein modules and signalling networks. Nature (1995) 12.53
NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor. J Biol Chem (1990) 5.91
Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol Cell Biol (1995) 5.71
Evidence that production and release of amyloid beta-protein involves the endocytic pathway. J Biol Chem (1994) 4.78
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature (1994) 4.49
Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain. Proc Natl Acad Sci U S A (1995) 4.10
The low density lipoprotein receptor. Identification of amino acids in cytoplasmic domain required for rapid endocytosis. J Biol Chem (1987) 3.84
Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain. Cell (1995) 3.65
Neuronal position in the developing brain is regulated by mouse disabled-1. Nature (1997) 3.60
Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice. Nature (1997) 3.22
A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains. J Biol Chem (1997) 3.19
An alternative to SH2 domains for binding tyrosine-phosphorylated proteins. Science (1994) 2.80
p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity. Genes Dev (1996) 2.77
Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein. J Biol Chem (1998) 2.71
Structure and ligand recognition of the phosphotyrosine binding domain of Shc. Nature (1995) 2.59
The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein. Mol Cell Biol (1996) 2.57
Ras-Raf interaction: two-hybrid analysis. Methods Enzymol (1995) 2.45
A phosphotyrosine interaction domain. Cell (1995) 2.28
A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors. J Biol Chem (1994) 2.06
Getting membrane flow and the cytoskeleton to cooperate in moving cells. Cell (1996) 2.04
Reelin-induced tyrosine [corrected] phosphorylation of disabled 1 during neuronal positioning. Genes Dev (1999) 2.02
Mouse disabled (mDab1): a Src binding protein implicated in neuronal development. EMBO J (1997) 1.95
Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor. Cell (1996) 1.92
SPOT synthesis. Epitope analysis with arrays of synthetic peptides prepared on cellulose membranes. Methods Mol Biol (1996) 1.89
Drosophila abl tyrosine kinase in embryonic CNS axons: a role in axonogenesis is revealed through dosage-sensitive interactions with disabled. Cell (1989) 1.85
Phosphoinositide-specific phospholipase C-delta 1 binds with high affinity to phospholipid vesicles containing phosphatidylinositol 4,5-bisphosphate. Biochemistry (1992) 1.82
The PTB domain: a new protein module implicated in signal transduction. Trends Biochem Sci (1995) 1.78
Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain. Mol Cell Biol (1995) 1.77
The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein. J Biol Chem (1995) 1.73
PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine. Science (1995) 1.68
pGSTag--a versatile bacterial expression plasmid for enzymatic labeling of recombinant proteins. Biotechniques (1992) 1.64
The role of the PH domain in the signal-dependent membrane targeting of Sos. EMBO J (1997) 1.54
Identification of a second SH2-domain-containing protein closely related to the phosphatidylinositol polyphosphate 5-phosphatase SHIP. Biochem Biophys Res Commun (1997) 1.54
Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product. J Biol Chem (1995) 1.52
Aberrant splicing of a mouse disabled homolog, mdab1, in the scrambler mouse. Neuron (1997) 1.49
Molecular cloning of differentially expressed genes in human epithelial ovarian cancer. Gynecol Oncol (1994) 1.48
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. EMBO J (1997) 1.48
The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion. J Biol Chem (1998) 1.45
Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system. Mol Cell Biol (1994) 1.41
Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein. J Biol Chem (1999) 1.38
Use of the two hybrid system to detect the association of the protein-tyrosine-phosphatase, SHPTP2, with another SH2-containing protein, Grb7. Oncogene (1996) 1.36
The LDL receptor clustering motif interacts with the clathrin terminal domain in a reverse turn conformation. J Cell Biol (1998) 1.29
The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system. FEBS Lett (1996) 1.27
The beta-amyloid domain is essential for axonal sorting of amyloid precursor protein. EMBO J (1996) 1.26
Intracellular routing of human amyloid protein precursor: axonal delivery followed by transport to the dendrites. J Neurosci Res (1995) 1.22
Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain. J Biol Chem (1995) 1.21
cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein. Hum Mol Genet (1996) 1.17
Trafficking of cell-surface amyloid beta-protein precursor. II. Endocytosis, recycling and lysosomal targeting detected by immunolocalization. J Cell Sci (1996) 1.17
High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif. Proc Natl Acad Sci U S A (1997) 1.15
Dosage-sensitive modifiers of Drosophila abl tyrosine kinase function: prospero, a regulator of axonal outgrowth, and disabled, a novel tyrosine kinase substrate. Genes Dev (1993) 1.14
Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo. Mol Cell Biol (1997) 1.08
Identification of residues within the SHC phosphotyrosine binding/phosphotyrosine interaction domain crucial for phosphopeptide interaction. J Biol Chem (1996) 0.97
The 'amyloid cascade hypothesis' of AD: decoy or real McCoy? Trends Neurosci (1997) 0.91
Disabled is a putative adaptor protein that functions during signaling by the sevenless receptor tyrosine kinase. Mol Cell Biol (1998) 0.87
Academic information in the academic health sciences center. Roles for the library in information management. J Med Educ (1982) 28.04
Predicting DNA duplex stability from the base sequence. Proc Natl Acad Sci U S A (1986) 21.73
Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell (1993) 16.91
Protein-tyrosine kinases. Annu Rev Biochem (1985) 14.83
Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector. Gene (1986) 13.92
Detection and quantification of phosphotyrosine in proteins. Methods Enzymol (1983) 11.89
Actin and actin-binding proteins. A critical evaluation of mechanisms and functions. Annu Rev Biochem (1986) 9.17
Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein. Nature (1985) 8.36
Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta. Nature (1987) 8.28
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature (2001) 7.31
Right ventricular dysplasia: a report of 24 adult cases. Circulation (1982) 6.54
Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA (2005) 5.60
Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. EMBO J (1997) 5.49
Regulation, substrates and functions of src. Biochim Biophys Acta (1996) 5.45
Pyrene actin: documentation of the validity of a sensitive assay for actin polymerization. J Muscle Res Cell Motil (1983) 5.36
Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin. Cell (1991) 5.10
Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells. Cell (1981) 5.08
Src family kinases are required for integrin but not PDGFR signal transduction. EMBO J (1999) 5.05
Tyr527 is phosphorylated in pp60c-src: implications for regulation. Science (1986) 4.99
Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature (1995) 4.95
A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability. EMBO J (1989) 4.91
The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid. Cell (1982) 4.66
Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins. Cell (1989) 4.52
Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane. Nature (1984) 4.27
Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro. J Biol Chem (1984) 4.20
Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation. Curr Biol (2001) 4.16
Homology of 54K protein of signal-recognition particle, docking protein and two E. coli proteins with putative GTP-binding domains. Nature (1989) 4.05
Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src. Mol Cell Biol (1986) 3.99
Dynamics of capping protein and actin assembly in vitro: uncapping barbed ends by polyphosphoinositides. J Cell Biol (1996) 3.97
Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src. Nature (1991) 3.97
Negative regulation of fibroblast motility by Ena/VASP proteins. Cell (2000) 3.89
Binding of GAP to activated PDGF receptors. Science (1990) 3.89
C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. J Biol Chem (1984) 3.88
The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol (2007) 3.81
Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast. Curr Opin Cell Biol (1995) 3.79
A yeast actin-related protein homologous to that in vertebrate dynactin complex is important for spindle orientation and nuclear migration. Cell (1994) 3.77
Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin. J Cell Biol (1994) 3.74
Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation. Neuron (1999) 3.70
Utility of a lung biopsy for the diagnosis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2001) 3.69
Neuronal position in the developing brain is regulated by mouse disabled-1. Nature (1997) 3.60
The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. Nat Immunol (2000) 3.58
The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain. Cell (1989) 3.51
Inducible expression vectors incorporating the Escherichia coli atpE translational initiation region. Gene (1987) 3.46
Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo. Mol Cell Biol (1999) 3.46
Movement of cortical actin patches in yeast. J Cell Biol (1996) 3.40
The return of Phineas Gage: clues about the brain from the skull of a famous patient. Science (1994) 3.40
Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation. Nature (1991) 3.30
Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation. Proc Natl Acad Sci U S A (1982) 3.28
Microtubule interactions with the cell cortex causing nuclear movements in Saccharomyces cerevisiae. J Cell Biol (2000) 3.25
Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice. Nature (1997) 3.22
DNA chain length markers and the influence of base composition on electrophoretic mobility of oligodeoxyribonucleotides in polyacrylamide-gels. Nucleic Acids Res (1979) 3.17
Quantitative analysis of the effect of Acanthamoeba profilin on actin filament nucleation and elongation. Biochemistry (1984) 3.15
In vitro translation of immediate early, early, and late classes of RNA from vaccinia virus-infected cells. Virology (1979) 2.97
Disruption of the actin cytoskeleton in yeast capping protein mutants. Nature (1990) 2.94
Mena is required for neurulation and commissure formation. Neuron (1999) 2.94
Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J Cell Biol (2000) 2.94
Similar effects of platelet-derived growth factor and epidermal growth factor on the phosphorylation of tyrosine in cellular proteins. Cell (1982) 2.92
Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro. Mol Cell Biol (1993) 2.87
Requirements for phosphorylation of MAP kinase during meiosis in Xenopus oocytes. Science (1992) 2.83
Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. Neuron (2000) 2.82
Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck). Mol Cell Biol (1988) 2.80
Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo. EMBO J (1992) 2.79
Phosphorylation of the PDGF receptor beta subunit creates a tight binding site for phosphatidylinositol 3 kinase. EMBO J (1990) 2.76
Visualization and molecular analysis of actin assembly in living cells. J Cell Biol (1998) 2.70
A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase. Mol Cell Biol (1994) 2.66
Cloned neuronal IK(A) channels reopen during recovery from inactivation. Nature (1991) 2.65
Expression of the vaccinia virus genome: analysis and mapping of mRNAs encoded within the inverted terminal repetition. Cell (1980) 2.63
Protein kinase C phosphorylates pp60src at a novel site. Cell (1985) 2.63
The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein. J Cell Biol (1986) 2.63
Role of proteins of the Ena/VASP family in actin-based motility of Listeria monocytogenes. J Cell Biol (1999) 2.62
Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA. EMBO J (1988) 2.60
Partial purification and characterization of early and late endosomes from yeast. Identification of four novel proteins. J Biol Chem (1993) 2.55
A new general approach for the simultaneous chemical synthesis of large numbers of oligonucleotides: segmental solid supports. Nucleic Acids Res (1983) 2.48
Hybridization selection and cell-free translation of mRNA's encoded within the inverted terminal repetition of the vaccinia virus genome. J Virol (1981) 2.48
Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virus. Nature (1983) 2.47
Flexural rigidity of microtubules measured with the use of optical tweezers. J Cell Sci (1996) 2.44
Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction. J Biol Chem (1998) 2.42
Statistical quality control of radioimmunoassays. J Clin Endocrinol Metab (1968) 2.41
Clinical pharmacology and therapeutic applications of the antiarrhythmic agent amiodarone. Am Heart J (1981) 2.41
Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways. Mol Cell Biol (1999) 2.39
Extension of the transcriptional and translational map of the left end of the vaccinia virus genome to 21 kilobase pairs. J Virol (1981) 2.39
Kinetic evidence for a monomer activation step in actin polymerization. Biochemistry (1983) 2.38
Effects of CapZ, an actin capping protein of muscle, on the polymerization of actin. Biochemistry (1989) 2.38
Evidence of apoptosis in arrhythmogenic right ventricular dysplasia. N Engl J Med (1996) 2.37
p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes. J Biol Chem (1997) 2.37
Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts. Mol Cell Biol (1991) 2.36
Tissue engineering: orthopedic applications. Annu Rev Biomed Eng (1999) 2.36
Regulation of cell growth and transformation by tyrosine-specific protein kinases: the search for important cellular substrate proteins. Curr Top Microbiol Immunol (1983) 2.32
Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen. Mol Cell Biol (1986) 2.32
Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2. Traffic (2001) 2.31
Rho family members: activators of MAP kinase cascades. Cell (1995) 2.29
Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells. J Biol Chem (1992) 2.29
Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells. Mol Cell Biol (1984) 2.28
Efficient construction of cDNA libraries in plasmid expression vectors using an adaptor strategy. Nucleic Acids Res (1986) 2.28
Restriction of the in vitro and in vivo tyrosine protein kinase activities of pp60c-src relative to pp60v-src. Mol Cell Biol (1985) 2.25