Mechanisms of myofibroblast activity and phenotypic modulation.

PubWeight™: 3.78‹?› | Rank: Top 1%

🔗 View Article (PMID 10413583)

Published in Exp Cell Res on August 01, 1999

Authors

G Serini1, G Gabbiani

Author Affiliations

1: Institute for Cancer Research and Treatment, Department of Genetics, Biology and Biochemistry, University of Torino School of Medicine, Str. Prov. 142, Km. 3.95, Candiolo (TO), 10060, Italy.

Articles citing this

(truncated to the top 100)

Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest (2003) 12.56

Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest (2002) 12.22

Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev (2008) 10.28

Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. J Clin Invest (2004) 7.91

Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol (2005) 5.88

Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell (2001) 4.25

An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers. Am J Pathol (2009) 3.15

Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation. Am J Pathol (2001) 3.07

Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proc Natl Acad Sci U S A (2010) 3.03

WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis. Am J Respir Cell Mol Biol (2009) 2.36

Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression. Semin Cell Dev Biol (2009) 2.25

Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair. Am J Pathol (2003) 2.22

Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury. Am J Pathol (2004) 2.17

Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching. Am J Pathol (2003) 2.14

Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylyl cyclase. Proc Natl Acad Sci U S A (2004) 2.02

Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction. Circ Res (2010) 2.00

Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. J Clin Invest (2011) 1.96

Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer. Proc Natl Acad Sci U S A (2011) 1.88

Caveolin-1-/- null mammary stromal fibroblasts share characteristics with human breast cancer-associated fibroblasts. Am J Pathol (2009) 1.87

The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo. J Cell Biol (2002) 1.82

NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts. J Am Soc Nephrol (2009) 1.80

Thy-1 expression in human fibroblast subsets defines myofibroblastic or lipofibroblastic phenotypes. Am J Pathol (2003) 1.75

Cancer-associated fibroblasts drive the progression of metastasis through both paracrine and mechanical pressure on cancer tissue. Mol Cancer Res (2012) 1.73

Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts. Mol Biol Cell (2003) 1.70

Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells. Br J Cancer (2004) 1.63

Myofibroblast development is characterized by specific cell-cell adherens junctions. Mol Biol Cell (2004) 1.56

The origin of interstitial myofibroblasts in chronic kidney disease. Pediatr Nephrol (2011) 1.55

Cell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3. Mol Cell Biol (2003) 1.49

Melanoma miRNA trafficking controls tumour primary niche formation. Nat Cell Biol (2016) 1.49

Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury. Am J Pathol (2005) 1.46

Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts. Lung (2005) 1.42

Fibronectin is an important regulator of flow-induced vascular remodeling. Arterioscler Thromb Vasc Biol (2009) 1.40

Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39

Characterisation of corneal fibrotic wound repair at the LASIK flap margin. Br J Ophthalmol (2003) 1.36

Extracellular matrix roles during cardiac repair. Life Sci (2010) 1.32

In vivo imaging of the systemic recruitment of fibroblasts to the angiogenic rim of ovarian carcinoma tumors. Cancer Res (2007) 1.30

Delayed stress fiber formation mediates pulmonary myofibroblast differentiation in response to TGF-β. Am J Physiol Lung Cell Mol Physiol (2011) 1.26

Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy? Semin Cell Dev Biol (2009) 1.23

Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiation. EMBO J (2005) 1.22

Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A. J Exp Med (2013) 1.21

Diminished type III collagen promotes myofibroblast differentiation and increases scar deposition in cutaneous wound healing. Cells Tissues Organs (2011) 1.19

Transient myofibroblast differentiation of interstitial fibroblastic cells relevant to tubular dilatation in uranyl acetate-induced acute renal failure in rats. Virchows Arch (2004) 1.18

TNF-alpha suppresses alpha-smooth muscle actin expression in human dermal fibroblasts: an implication for abnormal wound healing. J Invest Dermatol (2007) 1.16

Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation. J Invest Dermatol (2011) 1.16

Angiotensin II induces IL-6 expression and the Jak-STAT3 pathway in aortic adventitia of LDL receptor-deficient mice. Atherosclerosis (2006) 1.15

P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype. J Clin Invest (2002) 1.14

Myofibroblast numbers are elevated in human elbow capsules after trauma. Clin Orthop Relat Res (2004) 1.14

P21waf1/cip1/sdi1 as a central regulator of inducible smooth muscle actin expression and differentiation of cardiac fibroblasts to myofibroblasts. Mol Biol Cell (2007) 1.13

Factor Xa stimulates proinflammatory and profibrotic responses in fibroblasts via protease-activated receptor-2 activation. Am J Pathol (2008) 1.13

Ccr1 deficiency reduces inflammatory remodelling and preserves left ventricular function after myocardial infarction. J Cell Mol Med (2007) 1.12

Stretch-activated force shedding, force recovery, and cytoskeletal remodeling in contractile fibroblasts. J Biomech (2008) 1.09

CXCR4 and matrix metalloproteinase-1 are elevated in breast carcinoma-associated fibroblasts and in normal mammary fibroblasts exposed to factors secreted by breast cancer cells. Mol Cancer Res (2009) 1.09

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators. Mol Biol Cell (2004) 1.09

Reversal of TGF-β1 stimulation of α-smooth muscle actin and extracellular matrix components by cyclic AMP in Dupuytren's-derived fibroblasts. BMC Musculoskelet Disord (2011) 1.06

The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure. J Cell Biol (2002) 1.05

Skeletal myosin heavy chain function in cultured lung myofibroblasts. J Cell Biol (2003) 1.05

Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer. J Autoimmun (2009) 1.04

Differential trafficking of transforming growth factor-beta receptors and ligand in polarized epithelial cells. Mol Biol Cell (2004) 1.04

Acceleration of wound healing by growth hormone-releasing hormone and its agonists. Proc Natl Acad Sci U S A (2010) 1.03

Breast cancer stromal fibroblasts promote the generation of CD44+CD24- cells through SDF-1/CXCR4 interaction. J Exp Clin Cancer Res (2010) 1.03

Enhanced upregulation of smooth muscle related transcripts by TGF beta2 in asthmatic (myo) fibroblasts. Thorax (2006) 1.02

Reversible differentiation of myofibroblasts by MyoD. Exp Cell Res (2011) 1.02

Carcinoma-associated fibroblasts are a promising therapeutic target. Cancers (Basel) (2013) 1.01

Nuclear factor I-C links platelet-derived growth factor and transforming growth factor beta1 signaling to skin wound healing progression. Mol Cell Biol (2009) 1.00

Tumor-secreted LOXL2 activates fibroblasts through FAK signaling. Mol Cancer Res (2013) 0.99

Alteration of transforming growth factor-beta1 response involves down-regulation of Smad3 signaling in myofibroblasts from skin fibrosis. Am J Pathol (2001) 0.99

Exercise training reduces fibrosis and matrix metalloproteinase dysregulation in the aging rat heart. FASEB J (2010) 0.97

Cellular and molecular processes in ovarian cancer metastasis. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis. Am J Physiol Cell Physiol (2015) 0.97

In vitro effects of pirfenidone on cardiac fibroblasts: proliferation, myofibroblast differentiation, migration and cytokine secretion. PLoS One (2011) 0.96

Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function. Transl Res (2011) 0.96

The CXCR4-SDF1alpha axis is a critical mediator of rhabdomyosarcoma metastatic signaling induced by bone marrow stroma. Clin Exp Metastasis (2007) 0.95

Protease-activated receptor-2 induces myofibroblast differentiation and tissue factor up-regulation during bleomycin-induced lung injury: potential role in pulmonary fibrosis. Am J Pathol (2010) 0.95

In vitro wounding: effects of hypoxia and transforming growth factor beta1 on proliferation, migration and myofibroblastic differentiation in an endothelial cell-fibroblast co-culture model. J Mol Histol (2007) 0.94

Role of extracellular signal-regulated kinase, p38 kinase, and activator protein-1 in transforming growth factor-beta1-induced alpha smooth muscle actin expression in human fetal lung fibroblasts in vitro. Lung (2006) 0.94

Emerging roles of the tumor-associated stroma in promoting tumor metastasis. Cell Adh Migr (2012) 0.94

Typing of hepatic nonparenchymal cells using fibulin-2 and cytoglobin/STAP as liver fibrogenesis-related markers. Histochem Cell Biol (2004) 0.94

Cholesteatoma-associated fibroblasts modulate epithelial growth and differentiation through KGF/FGF7 secretion. Histochem Cell Biol (2012) 0.94

Cadherin-11 regulates cell-cell tension necessary for calcific nodule formation by valvular myofibroblasts. Arterioscler Thromb Vasc Biol (2012) 0.92

Dupuytren's: a systems biology disease. Arthritis Res Ther (2011) 0.91

Role of immune cells and inflammatory cytokines in regulation of fibrosis around silicone expander implants. J Mater Sci Mater Med (2010) 0.89

Pharmacological blockade of adenosine A2A receptors diminishes scarring. FASEB J (2012) 0.89

A unique element in the cytoplasmic tail of the type II transforming growth factor-beta receptor controls basolateral delivery. Mol Biol Cell (2007) 0.88

A cell-regulatory mechanism involving feedback between contraction and tissue formation guides wound healing progression. PLoS One (2014) 0.88

Smooth muscle α-actin is a direct target of PLZF: effects on the cytoskeleton and on susceptibility to oncogenic transformation. Oncotarget (2010) 0.88

AICAR-dependent AMPK activation improves scar formation in the aged heart in a murine model of reperfused myocardial infarction. J Mol Cell Cardiol (2013) 0.86

Role of IGF-1 pathway in lung fibroblast activation. Respir Res (2013) 0.85

Extra cellular matrix remodelling after heterotopic rat heart transplantation: gene expression profiling and involvement of ED-A+ fibronectin, alpha-smooth muscle actin and B+ tenascin-C in chronic cardiac allograft rejection. Histochem Cell Biol (2010) 0.84

GLIPR-2 overexpression in HK-2 cells promotes cell EMT and migration through ERK1/2 activation. PLoS One (2013) 0.84

Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients. J Transl Med (2012) 0.83

Suppression of injury-induced epithelial-mesenchymal transition in a mouse lens epithelium lacking tenascin-C. Mol Vis (2010) 0.83

The effect of the pro-inflammatory cytokine tumor necrosis factor-alpha on human joint capsule myofibroblasts. Arthritis Res Ther (2010) 0.83

Retromer maintains basolateral distribution of the type II TGF-β receptor via the recycling endosome. Mol Biol Cell (2013) 0.82

Inhibition of fibrous adhesion formation in the temporomandibular joint of tenascin-C knockout mice. Eur J Histochem (2014) 0.81

Interactions of the Extracellular Matrix and Progenitor Cells in Cutaneous Wound Healing. Adv Wound Care (New Rochelle) (2013) 0.81

Transforming growth factor-beta1 mediated up-regulation of lysyl oxidase in the kidneys of hereditary nephrotic mouse with chronic renal fibrosis. Virchows Arch (2005) 0.81

Nicotine inhibits myofibroblast differentiation in human gingival fibroblasts. J Cell Biochem (2005) 0.81

Response of fibroblasts to transforming growth factor-β1 on two-dimensional and in three-dimensional hyaluronan hydrogels. Tissue Eng Part A (2012) 0.81

Epithelial-mesenchymal transitions and the intersecting cell fate of fibroblasts and metastatic cancer cells. Trans Am Clin Climatol Assoc (2003) 0.81

Targeting Stromal-Cancer Cell Crosstalk Networks in Ovarian Cancer Treatment. Biomolecules (2016) 0.80

Overexpression of caveolin-1 in cancer-associated fibroblasts predicts good outcome in breast cancer. Breast Care (Basel) (2012) 0.80

Articles by these authors

(truncated to the top 100)

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol (1993) 8.36

A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol (1986) 6.83

Granulation tissue as a contractile organ. A study of structure and function. J Exp Med (1972) 5.42

Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia (1971) 5.14

Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing. Lab Invest (1990) 4.67

Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell (2001) 4.25

Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol (1995) 4.00

The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1. J Cell Biol (1998) 3.65

Human smooth muscle autoantibody. Its identification as antiactin antibody and a study of its binding to "nonmuscular" cells. Am J Pathol (1973) 3.36

Contraction of granulation tissue in vitro: similarity to smooth muscle. Science (1971) 3.29

Differentiation repertoire of fibroblastic cells: expression of cytoskeletal proteins as marker of phenotypic modulations. Lab Invest (1990) 3.15

Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation. Am J Pathol (2001) 3.07

Immunochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist. Am J Pathol (1981) 2.94

Vascular smooth muscle cells differ from other smooth muscle cells: predominance of vimentin filaments and a specific alpha-type actin. Proc Natl Acad Sci U S A (1981) 2.94

Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture. J Submicrosc Cytol Pathol (1992) 2.72

Morphological and immunochemical differences between keloid and hypertrophic scar. Am J Pathol (1994) 2.44

Dupuytren's contracture: fibroblast contraction? An ultrastructural study. Am J Pathol (1972) 2.31

Myofibroblasts from diverse pathologic settings are heterogeneous in their content of actin isoforms and intermediate filament proteins. Lab Invest (1989) 2.30

Alpha-smooth muscle actin, a differentiation marker of smooth muscle cells, is present in microfilamentous bundles of pericytes. J Histochem Cytochem (1989) 2.23

Expression of class II transplantation antigen on vascular smooth muscle cells in human atherosclerosis. J Clin Invest (1985) 2.16

Cytoskeleton of rat aortic smooth muscle cells. Normal conditions and experimental intimal thickening. Lab Invest (1984) 2.15

"Contractile interstitial cells" in pulmonary alveolar septa: a possible regulator of ventilation-perfusion ratio? Ultrastructural, immunofluorescence, and in vitro studies. J Cell Biol (1974) 2.11

Actin and tubulin co-cap with surface immunoglobulins in mouse B lymphocytes. Nature (1977) 2.10

Smooth-muscle differentiation in stromal cells of malignant and non-malignant breast tissues. Int J Cancer (1988) 2.01

Actin expression in smooth muscle cells of rat aortic intimal thickening, human atheromatous plaque, and cultured rat aortic media. J Clin Invest (1984) 1.95

The role of cytoskeletal and cytocontractile elements in pathologic processes. Am J Pathol (1983) 1.91

The myofibroblast: a quarter century after its discovery. Am J Surg Pathol (1998) 1.82

Heterogeneity of myofibroblast phenotypic features: an example of fibroblastic cell plasticity. Virchows Arch (1994) 1.79

Phalloidin-induced hyperplasia of actin filaments in rat hepatocytes. Lab Invest (1975) 1.78

Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors. J Cell Sci (2001) 1.75

Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells. J Exp Med (1989) 1.70

Myofibroblasts in human granulation tissue. Hum Pathol (1974) 1.68

Cytoskeletal protein modulation in pulmonary alveolar myofibroblasts during idiopathic pulmonary fibrosis. Possible role of transforming growth factor beta and tumor necrosis factor alpha. Am J Respir Crit Care Med (1995) 1.67

Proliferation and phenotypic modulation of portal fibroblasts in the early stages of cholestatic fibrosis in the rat. Lab Invest (1996) 1.65

Cellular events and intracellular survival of Campylobacter jejuni during infection of HEp-2 cells. Infect Immun (1989) 1.65

Alpha-smooth muscle actin is expressed in a subpopulation of cultured and cloned fibroblasts and is modulated by gamma-interferon. Exp Cell Res (1992) 1.64

Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers. Am J Pathol (1991) 1.62

Malignant soft tissue tumors of probable histiocytic origin (malignant fibrous histiocytomas): general considerations and electron microscopic and tissue culture studies. Cancer (1975) 1.62

Effect of gamma-interferon on the clinical and biologic evolution of hypertrophic scars and Dupuytren's disease: an open pilot study. Plast Reconstr Surg (1994) 1.58

Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques. Atherosclerosis (1988) 1.57

Cytoplasmic filaments and gap junctions in epithelial cells and myofibroblasts during wound healing. J Cell Biol (1978) 1.52

Distribution of vimentin and desmin filaments in smooth muscle tissue of mammalian and avian aorta. Exp Cell Res (1982) 1.52

Alpha-smooth muscle actin in parenchymal cells of bleomycin-injured rat lung. Lab Invest (1989) 1.50

The contractile fibroblast. Its relevance in plastic surgery. Plast Reconstr Surg (1973) 1.46

Intranuclear injection of anti-actin antibodies into Xenopus oocytes blocks chromosome condensation. Nature (1979) 1.45

Rat alveolar myofibroblasts acquire alpha-smooth muscle actin expression during bleomycin-induced pulmonary fibrosis. Am J Pathol (1993) 1.44

Differentiation of smooth muscle cells in human blood vessels as defined by smoothelin, a novel marker for the contractile phenotype. Arterioscler Thromb Vasc Biol (1997) 1.44

Collagen and myofibroblasts of granulation tissue. A chemical, ultrastructural and immunologic study. Virchows Arch B Cell Pathol (1976) 1.43

Identification of self-renewing myoblasts in the progeny of single human muscle satellite cells. Differentiation (1996) 1.43

Cytoskeletal features of rat aortic cells during development. An electron microscopic, immunohistochemical, and biochemical study. Circ Res (1985) 1.43

Polarized distribution of actin isoforms in gastric parietal cells. Mol Biol Cell (1995) 1.41

Cytoplasmic contractile apparatus in aortic endothelial cells of hypertensive rats. Lab Invest (1975) 1.41

Fibroblasts of granulation tissue: immunofluorescent staining with antismooth muscle serum. Proc Soc Exp Biol Med (1971) 1.41

An actin-destabilizing factor is present in human plasma. Experientia (1979) 1.41

A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture. Hepatology (1999) 1.40

Alpha-smooth muscle actin is transiently expressed in embryonic rat cardiac and skeletal muscles. Differentiation (1988) 1.39

Colonic pericryptal fibroblasts. Differentiation pattern in embryogenesis and phenotypic modulation in epithelial proliferative lesions. Virchows Arch A Pathol Anat Histopathol (1989) 1.39

Cytoskeletal features of normal and atheromatous human arterial smooth muscle cells. Hum Pathol (1986) 1.39

Apoptosis participates in cellularity regulation during rat aortic intimal thickening. Am J Pathol (1995) 1.39

Smooth muscle differentiation in scleroderma fibroblastic cells. Am J Pathol (1990) 1.36

Vimentin-containing smooth muscle cells in aortic intimal thickening after endothelial injury. Lab Invest (1982) 1.34

Actin isoform synthesis and mRNA levels in quiescent and proliferating rat aortic smooth muscle cells in vivo and in vitro. Lab Invest (1986) 1.33

Increase of contractile proteins in human cancer cells. Lancet (1975) 1.32

Apoptosis during wound healing, fibrocontractive diseases and vascular wall injury. Int J Biochem Cell Biol (1997) 1.32

Cytodifferentiation and expression of alpha-smooth muscle actin mRNA and protein during primary culture of aortic smooth muscle cells. Correlation with cell density and proliferative state. Arteriosclerosis (1989) 1.32

Locally applied GM-CSF induces the accumulation of alpha-smooth muscle actin containing myofibroblasts. Virchows Arch B Cell Pathol Incl Mol Pathol (1991) 1.31

Interferon-gamma inhibits experimental renal fibrosis. Kidney Int (1999) 1.30

Inhibition of rat hepatic lipocyte activation in culture by interferon-gamma. Hepatology (1992) 1.30

Mechanisms of neointima formation and remodeling in the porcine coronary artery. Circulation (2001) 1.28

Rat fibroblasts cultured from various organs exhibit differences in alpha-smooth muscle actin expression, cytoskeletal pattern, and adhesive structure organization. Exp Cell Res (1998) 1.27

Actin microfilaments, cell shape, and secretory processes in isolated rat hepatocytes. Effect of phalloidin and cytochalasin D. J Cell Biol (1979) 1.25

Phenotypic features of smooth muscle cells during the evolution of experimental carotid artery intimal thickening. Biochemical and morphologic studies. Lab Invest (1991) 1.25

Blood pressure-independent cardiac hypertrophy induced by locally activated renin-angiotensin system. Hypertension (1998) 1.25

The area of attachment of cytotoxic T lymphocytes to their target cells shows high motility and polarization of actin, but not myosin. J Immunol (1982) 1.23

Cultured porcine coronary artery smooth muscle cells. A new model with advanced differentiation. Circ Res (1999) 1.22

Specific demonstration of myoepithelial cells by anti-alpha smooth muscle actin antibody. J Histochem Cytochem (1988) 1.22

Intermediate filament proteins and actin isoforms as markers for soft tissue tumor differentiation and origin. II. Rhabdomyosarcomas. Am J Pathol (1988) 1.22

alpha-Actinin attached to membranes of secretory vesicles. Nature (1977) 1.20

The myofibroblast: a key cell for wound healing and fibrocontractive diseases. Prog Clin Biol Res (1981) 1.20

Lymphocyte alpha-actinin. Relationship to cell membrane and co-capping with surface receptors. J Cell Biol (1980) 1.20

Intermediate filament proteins and actin isoforms as markers for soft tissue tumor differentiation and origin. I. Smooth muscle tumors. Am J Pathol (1987) 1.19

Cytoskeletal remodeling of rat aortic smooth muscle cells in vitro: relationships to culture conditions and analogies to in vivo situations. J Submicrosc Cytol (1986) 1.19

Human plasma actin-depolymerizing factor. Purification, biological activity and localization in leukocytes and platelets. Eur J Biochem (1985) 1.19

Actin-isoform pattern as a marker of normal or pathological smooth-muscle and fibroblastic tissues. Differentiation (1987) 1.19

Organization of actin cytoskeleton in normal and regenerating arterial endothelial cells. Proc Natl Acad Sci U S A (1983) 1.18

Contractile proteins in human cancer cells. Immunofluorescent and electron microscopic study. Am J Pathol (1976) 1.18

Correlation between the distribution of smooth muscle or non muscle myosins and alpha-smooth muscle actin in normal and pathological soft tissues. Cell Motil Cytoskeleton (1988) 1.18

The intermediate filament proteins of rabbit normal epidermal Merkel cells are cytokeratins. J Invest Dermatol (1984) 1.17

Proteins of intermediate filaments. An immunohistochemical and biochemical approach to the classification of soft tissue tumors. Am J Pathol (1983) 1.16

Relationship between alpha-smooth muscle actin expression and fibrotic changes in human kidney. Exp Nephrol (1997) 1.16

Characterization of stromal cells with myoid features in lymph nodes and spleen in normal and pathologic conditions. Am J Pathol (1987) 1.15

Morphologic and functional changes of the aortic intima during experimental hypertension. Am J Pathol (1979) 1.15

Extracellular matrix deposition, lysyl oxidase expression, and myofibroblastic differentiation during the initial stages of cholestatic fibrosis in the rat. Lab Invest (1997) 1.12

Heparin induces alpha-smooth muscle actin expression in cultured fibroblasts and in granulation tissue myofibroblasts. Lab Invest (1992) 1.12

Coexpression of alpha-sarcomeric actin, alpha-smooth muscle actin and desmin during myogenesis in rat and mouse embryos I. Skeletal muscle. Differentiation (1990) 1.12

Distribution of intermediate filament proteins in normal and diseased human glomeruli. Am J Pathol (1986) 1.11

Cytoskeletal features of alveolar myofibroblasts and pericytes in normal human and rat lung. J Histochem Cytochem (1992) 1.11

Increased cardiac angiotensin II levels induce right and left ventricular hypertrophy in normotensive mice. Hypertension (2000) 1.11

Proliferative activity and alpha-smooth muscle actin expression in cultured rat aortic smooth muscle cells are differently modulated by transforming growth factor-beta 1 and heparin. Exp Cell Res (1994) 1.10

Biochemistry and histology of the connective tissue of Dupuytren's disease lesions. Eur J Clin Invest (1980) 1.10