Published in Mol Gen Genet on December 30, 1975
Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans. Proc Natl Acad Sci U S A (1979) 44.75
Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322. Proc Natl Acad Sci U S A (1978) 19.34
Filamentous coliphage M13 as a cloning vehicle: insertion of a HindII fragment of the lac regulatory region in M13 replicative form in vitro. Proc Natl Acad Sci U S A (1977) 18.85
A Tn3 lacZ transposon for the random generation of beta-galactosidase gene fusions: application to the analysis of gene expression in Agrobacterium. EMBO J (1985) 9.03
Heterogeneity of tetracycline resistance determinants in Streptococcus. J Bacteriol (1982) 6.20
Transposition of a plasmid deoxyribonucleic acid sequence that mediates ampicillin resistance: independence from host rec functions and orientation of insertion. J Bacteriol (1976) 4.13
Cloning and mapping of the replication origin of Escherichia coli. Proc Natl Acad Sci U S A (1977) 3.80
Evolution of Escherichia coli during growth in a constant environment. Genetics (1987) 3.44
Characterization of an Escherichia coli plasmid encoding for synthesis of heat-labile toxin: molecular cloning of the toxin determinant. Infect Immun (1978) 3.28
Determination of the functions of hemolytic plasmid pHly152 of Escherichia coli. J Bacteriol (1981) 2.77
Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo. Proc Natl Acad Sci U S A (1981) 2.63
Isolation and characterization of four plasmids from Bacillus subtilis. J Bacteriol (1977) 2.59
Control of ColE1 DNA replication: the rop gene product negatively affects transcription from the replication primer promoter. Proc Natl Acad Sci U S A (1982) 2.56
Studies of colicin E1 plasmid functions by analysis of deletions and TnA insertions of the plasmid. J Bacteriol (1977) 2.52
Hemolysis determinant common to Escherichia coli hemolytic plasmids of different incompatibility groups. J Bacteriol (1980) 2.51
Isolation, mapping, and examination of effects of TnA insertions in ColE1 plasmids. J Bacteriol (1977) 2.50
Cloning of replication, incompatibility, and stability functions of R plasmid NR1. J Bacteriol (1980) 2.40
Assignment of tra cistrons to EcoRI fragments of F sex factor DNA. J Bacteriol (1978) 2.32
Expression of the thymidylate synthetase gene of the Bacillus subtilis bacteriophage Phi-3-T in Escherichia coli. Proc Natl Acad Sci U S A (1976) 2.32
A plasmid cloning vehicle allowing regulated expression of eukaryotic DNA in bacteria. Proc Natl Acad Sci U S A (1976) 2.31
Exonucleases I, III, and V are required for stability of ColE1-related plasmids in Escherichia coli. J Bacteriol (1984) 2.29
Homology of the 3' terminal sequences of the 18S rRNA of Bombyx mori and the 16S rRNA of Escherchia coli. Nucleic Acids Res (1979) 2.08
Identification and characterization of the TolC protein, an outer membrane protein from Escherichia coli. J Bacteriol (1983) 2.00
Control of plasmid R1 replication: functions involved in replication, copy number control, incompatibility, and switch-off of replication. J Bacteriol (1980) 1.99
Clustering of genes involved in replication, copy number control, incompatibility, and stable maintenance of the resistance plasmid R1drd-19. J Bacteriol (1979) 1.80
Transformation-derived Neisseria gonorrhoeae plasmids with altered structure and function. J Bacteriol (1979) 1.78
Site-saturation studies of beta-lactamase: production and characterization of mutant beta-lactamases with all possible amino acid substitutions at residue 71. Proc Natl Acad Sci U S A (1986) 1.74
The nucleotide sequence of the bacteriocin promoters of plasmids Clo DF13 and Co1 E1: role of lexA repressor and cAMP in the regulation of promoter activity. Nucleic Acids Res (1982) 1.70
Molecular cloning of an Escherichia coli plasmid determinant than encodes for the production of heat-stable enterotoxin. J Bacteriol (1976) 1.69
Method for the genetic labeling of cryptic plasmids. J Bacteriol (1978) 1.69
Structural organization of a 67-kilobase streptococcal conjugative element mediating multiple antibiotic resistance. J Bacteriol (1985) 1.68
Expression of ribosomal protein genes cloned in a hybrid plasmid in Escherichia coli: gene dosage effects on synthesis of ribosomal proteins and ribosomal protein messenger ribonucleic acid. J Bacteriol (1979) 1.59
Aminoglycoside-modifying enzyme of an antibiotic-producing bacterium acts as a determinant of antibiotic resistance in Escherichia coli. Proc Natl Acad Sci U S A (1977) 1.57
Biochemical construction of specific chimeric plasmids from ColE1 DNA and unfractionated Escherichia coli DNA. Proc Natl Acad Sci U S A (1976) 1.53
recE4-Independent recombination between homologous deoxyribonucleic acid segments of Bacillus subtilis plasmids. J Bacteriol (1979) 1.53
Toluene transposons Tn4651 and Tn4653 are class II transposons. J Bacteriol (1989) 1.52
Tetracycline resistance genes from Bacillus plasmid pAB124 confer decreased accumulation of the antibiotic in Bacillus subtilis but not in Escherichia coli. J Bacteriol (1981) 1.52
Direct participation of lexA protein in repression of colicin E1 synthesis. J Bacteriol (1982) 1.51
Sequence and heterogeneity in the 5S RNA gene cluster of Drosophila melanogaster. Nucleic Acids Res (1980) 1.47
Sequence-specific recombination of plasmid ColE1. Proc Natl Acad Sci U S A (1980) 1.46
Regulated expression by readthrough translation from a plasmid-encoded beta-galactosidase. J Bacteriol (1978) 1.45
Sequence of the distal tRNA1Asp gene and the transcription termination signal in the Escherichia coli ribosomal RNA operon rrnF(or G). Nucleic Acids Res (1980) 1.45
Biochemical and immunological characterization of an R plasmid-encoded protein with properties resembling those of major cellular outer membrane proteins. J Bacteriol (1980) 1.45
Requirement of the Escherichia coli dnaA gene product for plasmid F maintenance. J Bacteriol (1986) 1.43
Cloning of the tyrP gene and further characterization of the tyrosine-specific transport system in Escherichia coli K-12. J Bacteriol (1984) 1.39
Fine cleavage map of a small colicin E1 plasmid carrying genes responsible for replication and colicin E1 immunity. J Bacteriol (1978) 1.39
Tn1331, a novel multiresistance transposon encoding resistance to amikacin and ampicillin in Klebsiella pneumoniae. Antimicrob Agents Chemother (1987) 1.36
Conjugative R plasmids in Streptococcus faecium (group D). Antimicrob Agents Chemother (1982) 1.35
Cointegrate formation between homologous plasmids in Escherichia coli. J Bacteriol (1982) 1.30
Isolation and genetic analysis of deletion mutants of colicin E1 plasmids carrying a TnA insertion. J Bacteriol (1977) 1.29
Self-assembly of single and closely spaced nucleosome core particles. Nucleic Acids Res (1980) 1.26
Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes. J Bacteriol (1991) 1.23
Identification and cloning of the genetic determinant that encodes for the K88ac adherence antigen. J Bacteriol (1981) 1.23
Genetic and molecular analysis of aroL, the gene for shikimate kinase II in Escherichia coli K-12. J Bacteriol (1986) 1.22
Biochemical characterization of HgCl2-inducible polypeptides encoded by the mer operon of plasmid R100. J Bacteriol (1982) 1.20
Characterization of ampicillin resistance plasmids from Haemophilus ducreyi. Antimicrob Agents Chemother (1982) 1.19
Plasmid-mediated susceptibility to intestinal microbial antagonisms in Escherichia coli. Infect Immun (1985) 1.19
Proteins synthesized in minicells containing plasmid ColE1 and its mutants. J Bacteriol (1978) 1.11
Isolation and characterization of ColE1-derived plasmid copy-number mutant. Proc Natl Acad Sci U S A (1978) 1.08
Molecular cloning and expression of the ilvGEDAY genes from Salmonella typhimurium. J Bacteriol (1981) 1.07
New mini-ColE1 as a molecular cloning vehicle. J Bacteriol (1977) 1.05
Binding between the par region of plasmids R1 and pSC101 and the outer membrane fraction of the host bacteria. EMBO J (1983) 1.03
Penicillinase-producing Neisseria gonorrhoeae: a molecular comparison of 5.3-kb and 7.4-kb beta-lactamase plasmids. J Bacteriol (1982) 1.01
Transduction of a bacterial gene into mammalian cells. Proc Natl Acad Sci U S A (1978) 1.00
Changes in protein synthesis on mitomycin C induction of wild-type and mutant CloDF13 plasmids. J Bacteriol (1977) 0.99
Isolation and characterization of a mutant ColE1 plasmid that allows constitutive colicin E1 synthesis. J Bacteriol (1979) 0.98
Location of an ampicillin resistance transposon, Tn1701, in a group of small, nontransferring plasmids. J Bacteriol (1979) 0.98
Plasmid pattern analysis of natural bacterial isolates and its epidemiological implication. J Hyg (Lond) (1983) 0.98
Involvement of DNA superhelicity in minichromosome maintenance in Escherichia coli. J Bacteriol (1985) 0.98
Studies on nucleic acid reassociation kinetics: V. Effects of disparity in tracer and driver fragment lengths. Nucleic Acids Res (1978) 0.97
Energetics of tetracycline transport into Escherichia coli. Antimicrob Agents Chemother (1984) 0.93
Mutations in the recD gene of Escherichia coli that raise the copy number of certain plasmids. J Bacteriol (1987) 0.92
Electron microscopic analysis of transcription: mapping of initiation sites and direction of transcription. Proc Natl Acad Sci U S A (1979) 0.91
Complementation of replication-deficient deletion derivatives of plasmid mini-F. J Bacteriol (1981) 0.86
A ColE1-encoded gene directs entry exclusion of the plasmid. J Bacteriol (1995) 0.86
Transcription of the stability operon of IncFII plasmid NR1. J Bacteriol (1991) 0.86
Studies on nucleic acid reassociation kinetics: retarded rate of hybridization of RNA with excess DNA. Proc Natl Acad Sci U S A (1977) 0.85
Four sizes of transcript produced by a single sea urchin gene expressed in early embryos. Proc Natl Acad Sci U S A (1980) 0.83
Corrected Version Distribution of Heterogeneous and Homologous Plasmids in Bacillus spp. Appl Environ Microbiol (1983) 0.80
Replication of plasmid DNA in Proteus mirabilis in limiting concentrations of thymine. J Bacteriol (1978) 0.76
Distribution of heterogeneous and homologous plasmids in Bacillus spp. Appl Environ Microbiol (1983) 0.75
dnaB analog function associated with plasmid R100drd-1. J Bacteriol (1983) 0.75
Spontaneous induction of colicin E1 in Escherichia coli strains deficient in both exonucleases I and V. J Bacteriol (1985) 0.75
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene (1977) 114.87
Simple agarose gel electrophoretic method for the identification and characterization of plasmid deoxyribonucleic acid. J Bacteriol (1976) 43.93
General method for the isolation of plasmid deoxyribonucleic acid. J Bacteriol (1973) 31.68
FACS-optimized mutants of the green fluorescent protein (GFP). Gene (1996) 24.12
The agent of bacillary angiomatosis. An approach to the identification of uncultured pathogens. N Engl J Med (1990) 15.92
Contribution of adhesion to bacterial persistence in the mouse urinary tract. Infect Immun (1983) 14.71
Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate. Infect Immun (1981) 14.05
Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis. Infect Immun (1981) 13.80
Identification of the uncultured bacillus of Whipple's disease. N Engl J Med (1992) 12.33
Uniform nomenclature for bacterial plasmids: a proposal. Bacteriol Rev (1976) 12.28
Polynucleotide sequence relationships among members of Enterobacteriaceae. J Bacteriol (1969) 11.27
Specific labeling and physical characterization of R-factor deoxyribonucleic acid in Escherichia coli. J Bacteriol (1970) 11.06
Coordinate regulation and sensory transduction in the control of bacterial virulence. Science (1989) 10.59
Common themes in microbial pathogenicity revisited. Microbiol Mol Biol Rev (1997) 10.52
Identification of invasin: a protein that allows enteric bacteria to penetrate cultured mammalian cells. Cell (1987) 9.80
A single genetic locus encoded by Yersinia pseudotuberculosis permits invasion of cultured animal cells by Escherichia coli K-12. Nature (1985) 9.45
Translocation of a plasmid DNA sequence which mediates ampicillin resistance: molecular nature and specificity of insertion. Proc Natl Acad Sci U S A (1975) 9.20
The enterotoxin plasmids of Escherichia coli. J Infect Dis (1974) 9.10
Origin of the TEM-beta-lactamase gene found on plasmids. J Bacteriol (1975) 8.70
Plasmid-linked ampicillin resistance in haempohilus influenza type b. Infect Immun (1975) 8.68
Tn5-induced mutations affecting virulence factors of Bordetella pertussis. Infect Immun (1983) 8.49
Molecular nature of two nonconjugative plasmids carrying drug resistance genes. J Bacteriol (1974) 8.42
Characterization of plasmid deoxyribonucleic acid from Neisseria gonorrhoeae. Infect Immun (1974) 8.30
Detection of enterotoxigenic Escherichia coli by DNA colony hybridization. J Infect Dis (1980) 8.15
Common themes in microbial pathogenicity. Microbiol Rev (1989) 7.78
Association of hemolysin production, hemagglutination of human erythrocytes, and virulence for chicken embryos of extraintestinal Escherichia coli isolates. Infect Immun (1978) 7.28
Pilus expression in Neisseria gonorrhoeae involves chromosomal rearrangement. Cell (1982) 7.19
A whole-genome microarray reveals genetic diversity among Helicobacter pylori strains. Proc Natl Acad Sci U S A (2000) 6.85
Evidence for two genetic loci in Yersinia enterocolitica that can promote invasion of epithelial cells. Infect Immun (1988) 6.68
Characterization of common virulence plasmids in Yersinia species and their role in the expression of outer membrane proteins. Infect Immun (1984) 6.63
The ability of Salmonella to enter mammalian cells is affected by bacterial growth state. Proc Natl Acad Sci U S A (1990) 6.57
Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc Natl Acad Sci U S A (1999) 6.34
Molecular epidemiology of Vibrio cholerae in the U.S. Gulf Coast. J Clin Microbiol (1982) 6.34
Plasmid-associated enterotoxin production in a strain of Escherichia coli isolated from humans. Infect Immun (1972) 6.21
Identification of enterotoxigenic Escherichia coli by colony hybridization using three enterotoxin gene probes. J Infect Dis (1982) 6.09
Amino acid sequence homology between cholera toxin and Escherichia coli heat-labile toxin. Nature (1980) 6.04
Polynucleotide sequence relationships among plasmids of the I compatibility complex. J Gen Microbiol (1974) 5.91
Haemolysin contributes to virulence of extra-intestinal E. coli infections. Nature (1981) 5.83
Organization and expression of genes responsible for type 1 piliation in Escherichia coli. J Bacteriol (1984) 5.83
Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches. J Exp Med (1994) 5.78
Shuttle mutagenesis: a method of transposon mutagenesis for Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1986) 5.75
Pilus retraction powers bacterial twitching motility. Nature (2000) 5.69
Nature of R-factor replication in the presence of chloramphenicol. Proc Natl Acad Sci U S A (1975) 5.64
Deletions affecting the transposition of an antibiotic resistance gene. Proc Natl Acad Sci U S A (1977) 5.48
Nucleotide sequence of the bacterial transposon Tn1681 encoding a heat-stable (ST) toxin and its identification in enterotoxigenic Escherichia coli strains. Proc Natl Acad Sci U S A (1980) 5.46
Cistrons encoding Escherichia coli heat-labile toxin. J Bacteriol (1979) 5.43
The problems of drug-resistant pathogenic bacteria. The replication of R-factor DNA in Escherichia coli K-12 following conjugation. Ann N Y Acad Sci (1971) 5.42
Pilus genes of Neisseria gonorrheae: chromosomal organization and DNA sequence. Proc Natl Acad Sci U S A (1984) 5.37
In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites. Proc Natl Acad Sci U S A (1978) 5.32
Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival. Mol Microbiol (1998) 5.25
Use of a single-strand specific nuclease for analysis of bacterial and plasmid deoxyribonucleic acid homo- and heteroduplexes. J Bacteriol (1973) 5.23
The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. Proc Natl Acad Sci U S A (1999) 5.17
Virulence-associated plasmids from Yersinia enterocolitica and Yersinia pestis. J Bacteriol (1981) 5.11
Salmonella typhimurium invasion induces apoptosis in infected macrophages. Proc Natl Acad Sci U S A (1996) 5.03
Genetic analysis of phase change in Bordetella pertussis. Infect Immun (1984) 5.03
Yeast-enhanced green fluorescent protein (yEGFP): a reporter of gene expression in Candida albicans. Microbiology (1997) 5.00
Fluorescence-based isolation of bacterial genes expressed within host cells. Science (1997) 4.98
Polynucleotide sequence divergence among strains of Escherichia coli and closely related organisms. J Bacteriol (1972) 4.87
Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence. Proc Natl Acad Sci U S A (1989) 4.87
Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. Proc Natl Acad Sci U S A (1989) 4.78
Intragenic recombination leads to pilus antigenic variation in Neisseria gonorrhoeae. Nature (1985) 4.60
Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant. Proc Natl Acad Sci U S A (1991) 4.57
Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Mol Microbiol (1996) 4.51
Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis. Cell (1990) 4.47
Molecular characterization of environmental and nontoxigenic strains of Vibrio cholerae. Infect Immun (1981) 4.45
Penetration of Salmonella through a polarized Madin-Darby canine kidney epithelial cell monolayer. J Cell Biol (1988) 4.44
Molecular relationships among the Salmonelleae. J Bacteriol (1973) 4.35
The meaning and impact of the human genome sequence for microbiology. Trends Microbiol (2001) 4.30
Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria. Nature (1993) 4.30
Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes. Nature (1999) 4.14
Isolation and nucleotide sequence determination of a gene encoding a heat-stable enterotoxin of Escherichia coli. Infect Immun (1983) 4.14
Transposition of a plasmid deoxyribonucleic acid sequence that mediates ampicillin resistance: independence from host rec functions and orientation of insertion. J Bacteriol (1976) 4.13
Salmonella interactions with polarized human intestinal Caco-2 epithelial cells. J Infect Dis (1990) 4.09
Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family. Science (2000) 4.08
Helicobacter pylori genetic diversity within the gastric niche of a single human host. Proc Natl Acad Sci U S A (2001) 4.05
Genetics of digalactoside-binding adhesin from a uropathogenic Escherichia coli strain. Infect Immun (1983) 4.03
Plasmid-mediated beta-lactamase production in Neisseria gonorrhoeae. Antimicrob Agents Chemother (1977) 4.02
The construction of a cloning vector designed for gene replacement in Bordetella pertussis. Gene (1986) 4.01
The E. coli gene encoding heat stable toxin is a bacterial transposon flanked by inverted repeats of IS1. Nature (1979) 3.94
Nucleotide sequence homology between the heat-labile enterotoxin gene of Escherichia coli and Vibrio cholerae deoxyribonucleic acid. J Bacteriol (1980) 3.89
Polynucleotide sequence relationships among Ent plasmids and the relationship between Ent and other plasmids. J Bacteriol (1975) 3.88
The molecular nature of R-factors. J Mol Biol (1966) 3.88
Comparison of the ability of enteroinvasive Escherichia coli, Salmonella typhimurium, Yersinia pseudotuberculosis, and Yersinia enterocolitica to enter and replicate within HEp-2 cells. Infect Immun (1987) 3.81
Identification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants. Proc Natl Acad Sci U S A (1992) 3.79
Molecular characterization of two beta-lactamase-specifying plasmids isolated from Neisseria gonorrhoeae. J Bacteriol (1977) 3.76
The ail locus is found uniquely in Yersinia enterocolitica serotypes commonly associated with disease. Infect Immun (1989) 3.75
Cloning and expression of an afimbrial adhesin (AFA-I) responsible for P blood group-independent, mannose-resistant hemagglutination from a pyelonephritic Escherichia coli strain. Infect Immun (1984) 3.75
Nucleotide sequence of the papA gene encoding the Pap pilus subunit of human uropathogenic Escherichia coli. J Bacteriol (1984) 3.73
Conjugal transfer of R plasmids in Neisseria gonorrhoeae. Nature (1977) 3.71
Analysis of sequences transposed by complementation of two classes of transposition-deficient mutants of Tn3. J Bacteriol (1978) 3.69
Detection of Shigella in feces using DNA amplification. J Infect Dis (1990) 3.61
Identification and characterization of TnphoA mutants of Salmonella that are unable to pass through a polarized MDCK epithelial cell monolayer. Mol Microbiol (1988) 3.59
Epithelial cell surfaces induce Salmonella proteins required for bacterial adherence and invasion. Science (1989) 3.55
Evidence for plasmid contribution to the virulence of fish pathogen Vibrio anguillarum. Infect Immun (1977) 3.49
Pertussis toxin and extracytoplasmic adenylate cyclase as virulence factors of Bordetella pertussis. J Infect Dis (1984) 3.48