Published in J Bacteriol on October 01, 1970
Nonchromosomal antibiotic resistance in bacteria: genetic transformation of Escherichia coli by R-factor DNA. Proc Natl Acad Sci U S A (1972) 57.06
General method for the isolation of plasmid deoxyribonucleic acid. J Bacteriol (1973) 31.68
Plasmid-controlled colonization factor associated with virulence in Esherichia coli enterotoxigenic for humans. Infect Immun (1975) 14.65
Molecular structure of bacterial plasmids. Bacteriol Rev (1972) 13.61
Properties of a R factor which originated in Pseudomonas aeruginosa 1822. J Bacteriol (1972) 8.56
Molecular nature of two nonconjugative plasmids carrying drug resistance genes. J Bacteriol (1974) 8.42
Nature of R-factor replication in the presence of chloramphenicol. Proc Natl Acad Sci U S A (1975) 5.64
Electron microscope heteroduplex studies of sequence relations among bacterial plasmids: identification and mapping of the insertion sequences IS1 and IS2 in F and R plasmids. J Bacteriol (1975) 5.44
Use of a single-strand specific nuclease for analysis of bacterial and plasmid deoxyribonucleic acid homo- and heteroduplexes. J Bacteriol (1973) 5.23
Molecular specificities of R factor-determined beta-lactamases: correlation with plasmid compatibility. J Bacteriol (1974) 5.06
Molecular and genetic studies of an R factor system consisting of independent transfer and drug resistance plasmids. J Bacteriol (1973) 4.81
Utilization of two distinct modes of replication by a hybrid plasmid constructed in vitro from separate replicons. Proc Natl Acad Sci U S A (1974) 4.27
Polynucleotide sequence relationships among some bacterial plasmids. J Bacteriol (1971) 3.38
Mutations in R factors of Escherichia coli causing an increased number of R-factor copies per chromosome. J Bacteriol (1972) 3.36
Studies on resistance transfer factor deoxyribonucleic acid in Escherichia coli. J Bacteriol (1970) 2.37
Genetic and physical characteristics of an enterotoxin plasmid. J Bacteriol (1975) 2.36
Absence of circular plasmid deoxyribonucleic acid attributable to a genetic determinant for methicillin resistance in Staphylococcus aureus. J Bacteriol (1973) 2.25
Physical properties and mechanism of transfer of R factors in Escherichia coli. J Bacteriol (1971) 2.06
Genetic and physiological analysis of an envB spherelike mutant of Escherichia coli K-12 and characterization of its transductants. J Bacteriol (1975) 2.05
Molecular structure of an R factor, its component drug-resistance determinants and transfer factor. J Bacteriol (1973) 1.94
Physical and functional characteristics of R-factor deoxyribonucleic acid segregated into Escherichia coli minicells. J Bacteriol (1971) 1.94
Properties of RP4, an R factor which originated in Pseudomonas aeruginosa S8. J Bacteriol (1972) 1.85
Replication of R-factor R1 in Scherichia coli K-12 at different growth rates. J Bacteriol (1975) 1.48
R62, a naturally occurring hybrid R plasmid. J Bacteriol (1974) 1.48
Molecular nature of R-factor deoxyribonucleic acid isolated from Salmonella typhimurium minicells. J Bacteriol (1973) 1.29
Elimination of resistance determinants from R-factor R1 by intercalative compounds. Antimicrob Agents Chemother (1976) 1.27
Additive recombination in bacteria. Bacteriol Rev (1977) 1.26
Suppression of an Escherichia coli dnaA mutation by the integrated R factor R100.1: generation of small plasmids after integration. J Bacteriol (1977) 1.11
Physical studies of the drug-resistance transfer factor in Proteus. J Bacteriol (1971) 1.11
Radioactive labelling of multiple-drug resistance factor in Escherichia coli. Biochem J (1971) 1.08
Extrachromosomal deoxyribonucleic acid in different enterobacteria. J Bacteriol (1973) 1.02
R-mediated beta-lactamases and episomal resistance to the beta-lactam drugs in different bacterial hosts. Antimicrob Agents Chemother (1974) 1.02
Molecular nature of the deoxyribonucleic acid of a thermosensitive R factor, Rts1. J Bacteriol (1974) 0.98
Membrane attachment of R-factor deoxyribonucleic acid in compatible and incompatible cell pairs following conjugation. J Bacteriol (1973) 0.98
Extrachromosomal deoxyribonucleic acid in R factor-harboring Enterobacteriaceae. J Bacteriol (1976) 0.93
Location of the region controlling host specificity (hsII) with respect to drug resistance markers on the fi - R factor, N-3. J Bacteriol (1972) 0.83
Genetic expression of sex-factor after transfer into irradiated cells of Escherichia coli uvrA. Biochem J (1971) 0.75
Replication of the deoxyribonucleic acid of multiple-drug-resistance factor in Escherichia coli. Biochem J (1976) 0.75
A method for determining the sedimentation behavior of enzymes: application to protein mixtures. J Biol Chem (1961) 59.20
SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA. J Mol Biol (1965) 36.76
Infective heredity of multiple drug resistance in bacteria. Bacteriol Rev (1963) 19.90
Physical and topological properties of circular DNA. J Gen Physiol (1966) 13.71
Episome-mediated transfer of drug resistance in Enterobacteriaceae. I. Transfer of resistance factors by conjugation. J Bacteriol (1961) 11.32
Evidence for circular DNA forms of a bacterial plasmid. Proc Natl Acad Sci U S A (1967) 10.45
Mutant drug resistant factors of high transmissibility. Nature (1967) 9.87
Multiple molecular species of circular R-factor DNA isolated from Escherichia coli. Nature (1969) 9.02
Composite circular forms of R factor deoxyribonucleic acid molecules. J Bacteriol (1969) 8.46
A general method for the isolation of RNA complementary to DNA. Proc Natl Acad Sci U S A (1962) 8.21
The ecology of transferable drug resistance in the enterobacteria. Annu Rev Microbiol (1968) 8.10
Studies on Escherichia coli sex factors. I. Specific labeling of F'Lac DNA. J Mol Biol (1968) 6.66
Molecular nature of the drug-resistance factors of the Enterobacteriaceae. J Mol Biol (1966) 6.11
Thymineless induction in Escherichia coli K12 (lambda). Biochim Biophys Acta (1962) 4.05
The molecular nature of R-factors. J Mol Biol (1966) 3.88
Studies on Escherichia coli sex factors. IV. Molecular weights of the DNA of several F' elements. J Mol Biol (1968) 3.30
Vegetative bacteriophage lambda-DNA. II. Physical characterization and replication. J Mol Biol (1967) 2.74
Transduction of various R factors by phage P1 in Escherichia coli and by phage P22 in Salmonella typhimurium. J Bacteriol (1968) 2.52
Studies on Escherichia coli sex factors. 3. Covalently closed F'Lac DNA molecules. J Mol Biol (1968) 2.45
Loss and repair of conjugal fertility and infectivity of the resistance factor and sex factor in Escherichia coli. J Bacteriol (1966) 1.95
Thermal chromatography of DNA-DNA reactions. Biophys J (1967) 1.92
The physical characterization of DNA molecules released from T2 and T4 bacteriophage. J Mol Biol (1961) 1.61
Transmissible drug-ressistance factor R with special reference to replication. Gunma J Med Sci (1965) 1.50
Episome-mediated transfer of drug resistance in Enterobacteriaceae. IX. Recombination of an R factor with F. J Bacteriol (1966) 1.43
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene (1977) 114.87
Simple agarose gel electrophoretic method for the identification and characterization of plasmid deoxyribonucleic acid. J Bacteriol (1976) 43.93
General method for the isolation of plasmid deoxyribonucleic acid. J Bacteriol (1973) 31.68
FACS-optimized mutants of the green fluorescent protein (GFP). Gene (1996) 24.12
The agent of bacillary angiomatosis. An approach to the identification of uncultured pathogens. N Engl J Med (1990) 15.92
Contribution of adhesion to bacterial persistence in the mouse urinary tract. Infect Immun (1983) 14.71
Plasmid-controlled colonization factor associated with virulence in Esherichia coli enterotoxigenic for humans. Infect Immun (1975) 14.65
Construction and expression of recombinant plasmids encoding type 1 or D-mannose-resistant pili from a urinary tract infection Escherichia coli isolate. Infect Immun (1981) 14.05
Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis. Infect Immun (1981) 13.80
Identification of the uncultured bacillus of Whipple's disease. N Engl J Med (1992) 12.33
Uniform nomenclature for bacterial plasmids: a proposal. Bacteriol Rev (1976) 12.28
Polynucleotide sequence relationships among members of Enterobacteriaceae. J Bacteriol (1969) 11.27
Coordinate regulation and sensory transduction in the control of bacterial virulence. Science (1989) 10.59
Common themes in microbial pathogenicity revisited. Microbiol Mol Biol Rev (1997) 10.52
Identification of invasin: a protein that allows enteric bacteria to penetrate cultured mammalian cells. Cell (1987) 9.80
A single genetic locus encoded by Yersinia pseudotuberculosis permits invasion of cultured animal cells by Escherichia coli K-12. Nature (1985) 9.45
Translocation of a plasmid DNA sequence which mediates ampicillin resistance: molecular nature and specificity of insertion. Proc Natl Acad Sci U S A (1975) 9.20
The enterotoxin plasmids of Escherichia coli. J Infect Dis (1974) 9.10
The generation of a ColE1-Apr cloning vehicle which allows detection of inserted DNA. Mol Gen Genet (1975) 8.80
Origin of the TEM-beta-lactamase gene found on plasmids. J Bacteriol (1975) 8.70
Plasmid-linked ampicillin resistance in haempohilus influenza type b. Infect Immun (1975) 8.68
Tn5-induced mutations affecting virulence factors of Bordetella pertussis. Infect Immun (1983) 8.49
Molecular nature of two nonconjugative plasmids carrying drug resistance genes. J Bacteriol (1974) 8.42
Six widespread bacterial clones among Escherichia coli K1 isolates. Infect Immun (1983) 8.35
Characterization of plasmid deoxyribonucleic acid from Neisseria gonorrhoeae. Infect Immun (1974) 8.30
Detection of enterotoxigenic Escherichia coli by DNA colony hybridization. J Infect Dis (1980) 8.15
Common themes in microbial pathogenicity. Microbiol Rev (1989) 7.78
Association of hemolysin production, hemagglutination of human erythrocytes, and virulence for chicken embryos of extraintestinal Escherichia coli isolates. Infect Immun (1978) 7.28
A whole-genome microarray reveals genetic diversity among Helicobacter pylori strains. Proc Natl Acad Sci U S A (2000) 6.85
Evidence for two genetic loci in Yersinia enterocolitica that can promote invasion of epithelial cells. Infect Immun (1988) 6.68
Characterization of common virulence plasmids in Yersinia species and their role in the expression of outer membrane proteins. Infect Immun (1984) 6.63
The ability of Salmonella to enter mammalian cells is affected by bacterial growth state. Proc Natl Acad Sci U S A (1990) 6.57
Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc Natl Acad Sci U S A (1999) 6.34
Molecular epidemiology of Vibrio cholerae in the U.S. Gulf Coast. J Clin Microbiol (1982) 6.34
Plasmid-associated enterotoxin production in a strain of Escherichia coli isolated from humans. Infect Immun (1972) 6.21
Identification of enterotoxigenic Escherichia coli by colony hybridization using three enterotoxin gene probes. J Infect Dis (1982) 6.09
Amino acid sequence homology between cholera toxin and Escherichia coli heat-labile toxin. Nature (1980) 6.04
Polynucleotide sequence relationships among plasmids of the I compatibility complex. J Gen Microbiol (1974) 5.91
Haemolysin contributes to virulence of extra-intestinal E. coli infections. Nature (1981) 5.83
Organization and expression of genes responsible for type 1 piliation in Escherichia coli. J Bacteriol (1984) 5.83
Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches. J Exp Med (1994) 5.78
Nature of R-factor replication in the presence of chloramphenicol. Proc Natl Acad Sci U S A (1975) 5.64
Deletions affecting the transposition of an antibiotic resistance gene. Proc Natl Acad Sci U S A (1977) 5.48
Cistrons encoding Escherichia coli heat-labile toxin. J Bacteriol (1979) 5.43
The problems of drug-resistant pathogenic bacteria. The replication of R-factor DNA in Escherichia coli K-12 following conjugation. Ann N Y Acad Sci (1971) 5.42
Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival. Mol Microbiol (1998) 5.25
Use of a single-strand specific nuclease for analysis of bacterial and plasmid deoxyribonucleic acid homo- and heteroduplexes. J Bacteriol (1973) 5.23
The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. Proc Natl Acad Sci U S A (1999) 5.17
Virulence-associated plasmids from Yersinia enterocolitica and Yersinia pestis. J Bacteriol (1981) 5.11
Salmonella typhimurium invasion induces apoptosis in infected macrophages. Proc Natl Acad Sci U S A (1996) 5.03
Genetic analysis of phase change in Bordetella pertussis. Infect Immun (1984) 5.03
Yeast-enhanced green fluorescent protein (yEGFP): a reporter of gene expression in Candida albicans. Microbiology (1997) 5.00
Fluorescence-based isolation of bacterial genes expressed within host cells. Science (1997) 4.98
Polynucleotide sequence divergence among strains of Escherichia coli and closely related organisms. J Bacteriol (1972) 4.87
Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence. Proc Natl Acad Sci U S A (1989) 4.87
Nonchromosomal antibiotic resistance in bacteria. V. Isolation and characterization of R factor mutants exhibiting temperature-sensitive repression of fertility. J Bacteriol (1972) 4.85
Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. Proc Natl Acad Sci U S A (1989) 4.78
Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant. Proc Natl Acad Sci U S A (1991) 4.57
Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Mol Microbiol (1996) 4.51
Recognition of a bacterial adhesion by an integrin: macrophage CR3 (alpha M beta 2, CD11b/CD18) binds filamentous hemagglutinin of Bordetella pertussis. Cell (1990) 4.47
Molecular characterization of environmental and nontoxigenic strains of Vibrio cholerae. Infect Immun (1981) 4.45
Penetration of Salmonella through a polarized Madin-Darby canine kidney epithelial cell monolayer. J Cell Biol (1988) 4.44
Molecular relationships among the Salmonelleae. J Bacteriol (1973) 4.35
The meaning and impact of the human genome sequence for microbiology. Trends Microbiol (2001) 4.30
Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria. Nature (1993) 4.30
Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes. Nature (1999) 4.14
Isolation and nucleotide sequence determination of a gene encoding a heat-stable enterotoxin of Escherichia coli. Infect Immun (1983) 4.14
Transposition of a plasmid deoxyribonucleic acid sequence that mediates ampicillin resistance: independence from host rec functions and orientation of insertion. J Bacteriol (1976) 4.13
Salmonella interactions with polarized human intestinal Caco-2 epithelial cells. J Infect Dis (1990) 4.09
Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE-PGRS family. Science (2000) 4.08
Helicobacter pylori genetic diversity within the gastric niche of a single human host. Proc Natl Acad Sci U S A (2001) 4.05
Genetics of digalactoside-binding adhesin from a uropathogenic Escherichia coli strain. Infect Immun (1983) 4.03
Plasmid-mediated beta-lactamase production in Neisseria gonorrhoeae. Antimicrob Agents Chemother (1977) 4.02
The construction of a cloning vector designed for gene replacement in Bordetella pertussis. Gene (1986) 4.01
Isolation of catenated forms of R factor DNA from minicells. Nat New Biol (1971) 3.99
Nucleotide sequence homology between the heat-labile enterotoxin gene of Escherichia coli and Vibrio cholerae deoxyribonucleic acid. J Bacteriol (1980) 3.89
Polynucleotide sequence relationships among Ent plasmids and the relationship between Ent and other plasmids. J Bacteriol (1975) 3.88
The molecular nature of R-factors. J Mol Biol (1966) 3.88
Comparison of the ability of enteroinvasive Escherichia coli, Salmonella typhimurium, Yersinia pseudotuberculosis, and Yersinia enterocolitica to enter and replicate within HEp-2 cells. Infect Immun (1987) 3.81
Identification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants. Proc Natl Acad Sci U S A (1992) 3.79
Molecular characterization of two beta-lactamase-specifying plasmids isolated from Neisseria gonorrhoeae. J Bacteriol (1977) 3.76
The ail locus is found uniquely in Yersinia enterocolitica serotypes commonly associated with disease. Infect Immun (1989) 3.75
Cloning and expression of an afimbrial adhesin (AFA-I) responsible for P blood group-independent, mannose-resistant hemagglutination from a pyelonephritic Escherichia coli strain. Infect Immun (1984) 3.75
Nucleotide sequence of the papA gene encoding the Pap pilus subunit of human uropathogenic Escherichia coli. J Bacteriol (1984) 3.73
Conjugal transfer of R plasmids in Neisseria gonorrhoeae. Nature (1977) 3.71
Analysis of sequences transposed by complementation of two classes of transposition-deficient mutants of Tn3. J Bacteriol (1978) 3.69
Detection of Shigella in feces using DNA amplification. J Infect Dis (1990) 3.61
Identification and characterization of TnphoA mutants of Salmonella that are unable to pass through a polarized MDCK epithelial cell monolayer. Mol Microbiol (1988) 3.59
Epithelial cell surfaces induce Salmonella proteins required for bacterial adherence and invasion. Science (1989) 3.55
Evidence for plasmid contribution to the virulence of fish pathogen Vibrio anguillarum. Infect Immun (1977) 3.49
Pertussis toxin and extracytoplasmic adenylate cyclase as virulence factors of Bordetella pertussis. J Infect Dis (1984) 3.48
Phase variation in Bordetella pertussis by frameshift mutation in a gene for a novel two-component system. Nature (1989) 3.48
Genetics of the Enterobacteriaceae. C. Molecular relationships among members of the Enterobacteriaceae. Adv Genet (1971) 3.43
Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death. Proc Natl Acad Sci U S A (1997) 3.43
Salmonellosis: host immune responses and bacterial virulence determinants. Annu Rev Immunol (1996) 3.41
Signal transduction in the mammalian cell during bacterial attachment and entry. Cell (1993) 3.41
Polynucleotide sequence relationships among some bacterial plasmids. J Bacteriol (1971) 3.38
Attaching and effacing locus of a Citrobacter freundii biotype that causes transmissible murine colonic hyperplasia. Infect Immun (1993) 3.34